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1 1H-NMR spectroscopy combined with pattern recognition analysis reveals characteristic chemical patterns in urines of MS patients and non-human primates with MS-like disease
article 2003    
Author: Hart, B.A. 't · Vogels, J.T.W.E. · Spijksma, G. · Brok, H.P.M. · Polman, C. · Greef, J. van der
Keywords: Biology · Analytical research · Inflammatory demyelination · MS disease markers · NMR spectroscopy · Pattern recognition · Urine · myelin protein · organic compound · glycoprotein · tritium · animal model · article · autoimmune disease · chemical composition · clinical article · controlled study · disease course · encephalomyelitis · female · human · male · marmoset · molecular recognition · multiple sclerosis · multivariate analysis · nonhuman · primate · priority journal · proton nuclear magnetic resonance · urinalysis · validation process · allergic encephalomyelitis · animal · automated pattern recognition · chemistry · comparative study · disease model · immunization · immunology · methodology · nuclear magnetic resonance spectroscopy · species difference · time · urine · Animals · Callithrix · Disease Models, Animal · Encephalomyelitis, Autoimmune, Experimental · Female · Glycoproteins · Humans · Immunization · Magnetic Resonance Spectroscopy · Male · Multiple Sclerosis · Multivariate Analysis · Myelin Proteins · Pattern Recognition, Automated · Species Specificity · Time Factors · Tritium · Urine
[Abstract]

2 Uniform procedure of 1H NMR analysis of rat urine and toxicometabonomics Part II : Comparison of NMR profiles classification of hepatotoxicity
article 2007    
Author: Schoonen, W.G.E.J. · Kloks, C.P.A.M. · Ploemen, J.-P.H.T.M. · Smit, M.J. · Zandberg, P. · Horbach, G.J. · Mellema, J.-R. · Zuylen, C.T. van · Tas, A.C. · Nesselrooij, J.H.J. van · Vogels, J.T.W.E.
Keywords: Biology · Analytical research · Cholestasis · Hepatotoxicity · Metabonomics · Necrosis · NMR · Steatosis · Urinalysis · 1 naphthyl isothiocyanate · biological marker · bromobenzene · carbon tetrachloride · chlorpromazine · ethinylestradiol · ibuprofen · iproniazid · isoniazid · methyltestosterone · mianserin · paracetamol · phenobarbital · placebo · tetracycline · thioacetamide · animal experiment · animal tissue · article · controlled study · diagnostic accuracy · diagnostic value · drug blood level · drug urine level · early diagnosis · fatty liver · histopathology · intermethod comparison · intrahepatic cholestasis · liver necrosis · liver toxicity · male · nonhuman · pattern recognition · prediction · principal component analysis · proton nuclear magnetic resonance · rat · urinalysis · Animals · Biological Markers · Cholestasis · Fatty Liver · Hepatitis, Toxic · Liver · Magnetic Resonance Spectroscopy · Male · Necrosis · Pattern Recognition, Automated · Principal Component Analysis · Rats · Rats, Wistar · Urine · Animalia · Rattus
[Abstract]

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