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1 Dose effects of ammonium perfluorooctanoate on Lipoprotein Metabolism in APOE*3-Leiden.CETP mice
article 2019    
Author: Pouwer, M.G. · Pieterman, E.J. · Chang, S.C. · Olsen, G.W. · Verschuren, L. · Jukema, J.W. · Princen, H.M.G.
Keywords: Health · Cholesterol · Lipoproteins · Non-HDL cholesterol · Perfluorooctanoic acid (PFOA) · Peroxisome proliferator-activated receptor (PPAR)α · Triglycerides · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · ELSS - Earth, Life and Social Sciences
[PDF] [Abstract]

2 Comparative transcriptomic and metabolomic analysis of fenofibrate and fish oil treatments in mice
article 2011    
Author: Lu, Y. · Boekschoten, M.V. · Wopereis, S. · Müller, M. · Kersten, S.
Keywords: Biology · Complement and coagulation cascades · Lipid metabolism · Liver · Peroxisome proliferator-activated receptor · amino acid · cholesterol · fenofibrate · fish oil · peroxisome proliferator activated receptor alpha · triacylglycerol · amino acid blood level · animal experiment · arachidonic acid metabolism · article · cardiovascular risk · cholesterol blood level · citric acid cycle · comparative study · controlled study · down regulation · fatty acid metabolism · fatty acid synthesis · gene control · male · metabolomics · mouse · nonhuman · priority journal · transcriptomics · treatment duration · triacylglycerol blood level · upregulation · Healthy Living · Life · MSB - Microbiology and Systems Biology · EELS - Earth, Environmental and Life Sciences
[Abstract]

3 Evidence for anti-inflammatory activity of statins and PPARα activators in human C-reactive protein transgenic mice in vivo and in cultured human hepatocytes in vitro
article 2004    
Author: Kleemann, R. · Verschuren, L. · Rooij, B.J. de · Lindeman, J. · Maat, M.M.de · Szalai, A.J. · Princen, H.M.G. · Kooistra, T.
Keywords: Biomedical Research · Antilipemic agent · C reactive protein · CCAAT enhancer binding protein · Cholesterol · Fenofibrate · Hydroxymethylglutaryl coenzyme A reductase inhibitor · I kappa B alpha · Immunoglobulin enhancer binding protein · Interleukin 1beta · Peroxisome proliferator activated receptor agonist · Peroxisome proliferator activated receptor alpha · Peroxisome proliferator activated receptor alpha agonist · Pirinixic acid · Protein p50 · Unclassified drug · Animal experiment · Animal model · Animal tissue · Antiinflammatory activity · Atherogenesis · Atherosclerosis · Cardiovascular risk · Cell culture · Cholesterol blood level · Controlled study · Hepatoma cell · Human cell · Inflammation · Liver cell · Mouse · Nonhuman · Transgenic mouse · Animals · C-Reactive Protein · Carcinoma, Hepatocellular · CCAAT-Enhancer-Binding Proteins · Cell Line, Tumor · Cholesterol · Down-Regulation · Gene Expression · Hepatocytes · Heptanoic Acids · Humans · Hydroxymethylglutaryl-CoA Reductase Inhibitors · I-kappa B Proteins · Interleukin-1 · Male · Mice · Mice, Transgenic · NF-kappa B · NF-kappa B p50 Subunit · Pyrroles · Receptors, Cytoplasmic and Nuclear · Simvastatin · Transcription Factors · Up-Regulation
[Abstract]

4 The dual PPARα/γ agonist tesaglitazar blocks progression of pre-existing atherosclerosis in APOE*3Leiden.CETP transgenic mice
article 2009    
Author: Hoorn, J.W.A. van der · Jukema, J.W. · Havekes, L.M. · Lundholm, E. · Camejo, G. · Rensen, P.C.N. · Princen, H.M.G.
Keywords: Biology · Biomedical Research · 3Leiden.CETP mice · APOE · Atherogenic triad · Atherosclerosis · PPARα/γ · Tesaglitazar · 2 ethoxy 3 (4 ((4 (methylsulfonyloxy)phenethyl)oxy)phenyl)propanoic acid · Alkanesulfonic acid · High density lipoprotein cholesterol · Peroxisome proliferator activated receptor alpha · Peroxisome proliferator activated receptor gamma · Phenylpropionic acid derivative · Very low density lipoprotein cholesterol · Biosynthesis · Blood · Drug potentiation · Genetics · Inflammation · Metabolism · Mouse · Mutation · Pathology · Transgenic mouse · Alkanesulfonates · Animals · Aortic Valve · Apolipoprotein E3 · Atherosclerosis · Cholesterol Ester Transfer Proteins · Cholesterol, HDL · Cholesterol, VLDL · Female · Humans · Inflammation · Mice · Mice, Transgenic · Mutation · Phenylpropionates · PPAR alpha · PPAR gamma
[Abstract]

5 Overexpression of APOC1 in obob mice leads to hepatic steatosis and severe hepatic insulin resistance
article 2004    
Author: Muurling, M. · Hoek, A.M. van den · Mensink, R.P. · Pijl, H. · Romijn, J.A. · Havekes, L.M. · Voshol, P.J.
Keywords: Biology · Biomedical Research · Free fatty acid metabolism · Hepatic fat accumulation · Lipid metabolism · Peroxisome proliferator-activated receptor-γ · Rosiglitazone · Diacylglycerol · Glucose · Ketone body · Peroxisome proliferator activated receptor gamma · Rosiglitazone · Triacylglycerol · Adipose tissue · Animal experiment · Animal model · Animal tissue · APOC1 gene · Cholesterol blood level · Controlled study · Fatty acid metabolism · Gene · Gene overexpression · Gluconeogenesis · Glucose blood level · Glucose transport · Hyperglycemia · Hyperinsulinemia · Hyperlipidemia · Insulin blood level · Insulin resistance · Lipid metabolism · Lipid storage · Mouse · Nonhuman · Obesity · Transgenic mouse · Triacylglycerol blood level · Weight reduction · Animals · Apolipoprotein C-I · Apolipoproteins C · Blood Glucose · Body Weight · Fatty Acids · Fatty Liver · Gene Expression · Humans · Hyperglycemia · Hyperinsulinism · Hyperlipidemias · Insulin · Insulin Resistance · Mice · Mice, Transgenic
[PDF] [Abstract]

6 Dual PPARα/γ agonist tesaglitazar reduces atherosclerosis in insulin-resistant and hypercholesterolemic ApoE*3Leiden mice
article 2006    
Author: Zadelaar, A.S.M. · Boesten, L.S.M. · Jukema, J.W. · Vlijmen, B.J.M. van · Kooistra, T. · Emeis, J.J. · Lundholm, E. · Camejo, G. · Havekes, L.M.
Keywords: Cholesterol · Inhibitors · Collagen · Immunoglobulin enhancer binding protein · Serum amyloid A · Tesaglitazar · 2 ethoxy 3 (4 ((4 (methylsulfonyloxy)phenethyl)oxy)phenyl)propanoic acid · Alkanesulfonic acid · Apolipoprotein E3 (Leidein) · Biological marker · Lipoprotein · Peroxisome proliferator activated receptor alpha · Peroxisome proliferator activated receptor gamma · Phenylpropionic acid derivative · Animal cell · Animal experiment · Animal model · Animal tissue · Blood vessel wall · Cholesterol blood level · Controlled study · Diet · Enzyme activity · Monocyte · Mouse · Nonhuman · Protein blood level · Transgenic mouse · Blood · Cholesterol intake · Drug potentiation · Fat intake · Metabolism · Pathology · Pathophysiology · Alkanesulfonates · Animals · Apolipoprotein E3 · Apolipoproteins E · Atherosclerosis · Biological Markers · Blood Vessels · Cell Adhesion · Cholesterol · Cholesterol, Dietary · Collagen · Dietary Fats · Female · Hypercholesterolemia · Inflammation · Insulin Resistance · Lipids · Lipoproteins · Macrophages · Mice · Mice, Transgenic · Monocytes · NF-kappa B · Phenylpropionates · PPAR alpha · PPAR gamma
[Abstract]

7 Global Suppression of IL-6-induced Acute Phase Response Gene Expression after Chronic in Vivo Treatment with the Peroxisome Proliferator-activated Receptor-α Activator Fenofibrate
article 2004    
Author: Gervois, P. · Kleemann, R. · Pilon, A. · Percevault, F. · Koenig, W. · Staels, B. · Kooistra, T.
Keywords: Biology · Biomedical Research · Biological organs · Enzyme kinetics · Lipids · Metabolism · Patient treatment · Plasmas · Acute phase response (APR) · Gene expression · Genetic engineering · Albumin · Alpha 2 macroglobulin · CCAAT enhancer binding protein · CCAAT enhancer binding protein alpha · CCAAT enhancer binding protein beta · CCAAT enhancer binding protein delta · Fenofibrate · Fibrinogen · Interleukin 6 · peroxisome proliferator activated receptor agonist · peroxisome proliferator activated receptor alpha · serum amyloid A · STAT3 protein · Stress activated protein kinase · Transcription factor · Unclassified drug · Acute phase response · Animal experiment · Animal tissue · Clinical article · Controlled study · Down regulation · Enzyme activation · Fibrinogen blood level · Gene expression regulation · Hyperlipidemia · In vivo study · Knockout mouse · Liver · Long term care · Male · Mouse · Nonhuman · Protein expression · Protein function · Protein phosphorylation · Transcription regulation · Wild type · Acute-Phase Reaction · Animals · Antilipemic Agents · Apolipoproteins · Down-Regulation · Fibrinogen · Haptoglobins · Humans · Interleukin-6 · Mice · Procetofen · Receptors, Cytoplasmic and Nuclear · Serum Amyloid A Protein · Signal Transduction · Transcription Factors · Animalia · Eukaryota
[PDF] [Abstract]

8 Fenofibrate increases HDL-cholesterol by reducing cholesteryl ester transfer protein expression
article 2007    
Author: Hoogt, C.C. van der · Haan, W. de · Westerterp, M. · Hoekstra, M. · Dallinga-Thie, G.M. · Romijn, J.A. · Princen, H.M.G. · Jukema, J.W. · Havekes, L.M. · Rensen, P.C.N.
Keywords: Health · Biomedical Research · Fibrate · High density lipoprotein · Peroxisome proliferator-activated receptor α · Transgenic mice · apolipoprotein E · cholesterol ester transfer protein · fenofibrate · high density lipoprotein cholesterol · very low density lipoprotein · animal experiment · cholesterol transport · controlled study · drug mechanism · food intake · gene expression · lipid metabolism · mouse · nonhuman · priority journal · protein expression · protein function · steady state · transgene · Animals · Antilipemic Agents · Apolipoproteins B · Cholesterol Ester Transfer Proteins · Cholesterol Esters · Cholesterol, HDL · Gene Expression · Humans · Liver · Male · Mice · Mice, Transgenic · Procetofen · RNA, Messenger
[PDF] [Abstract]

9 Differentiation of adipose stem cells by nucleus pulposus cells: Configuration effect
article 2007    
Author: Lu, Z.F. · Zandieh Doulabi, B. · Wuisman, P.I. · Bank, R.A. · Helder, M.N.
Keywords: Biomedical Research · Adipose tissue · Chondrogenic differentiation · Co-culture · Disc regeneration · Gene expression · Mesenchymal stem cells · Nucleus pulposus · aggrecan · collagen type 1 · collagen type 3 · osteopontin · peroxisome proliferator activated receptor gamma · adipose tissue cell · chondrogenesis · controlled study · down regulation · gene expression · genetic analysis · monolayer culture · nucleus pulposus · phenotype · priority journal · real time polymerase chain reaction · stem cell · upregulation · Adipocytes · Cell Culture Techniques · Cell Differentiation · Cells, Cultured · Coculture Techniques · Humans · Intervertebral Disk · Stem Cells
[Abstract]

10 The direct peroxisome proliferator-activated receptor target fasting-induced adipose factor (FIAF/PGAR/ANGPTL4) is present in blood plasma as a truncated protein that is increased by fenofibrate treatment
article 2004    
Author: Mandard, S. · Zandbergen, F. · Nguan, S.T. · Escher, P. · Patsouris, D. · Koenig, W. · Kleemann, R. · Bakker, A. · Veenman, F. · Wahli, W. · Müller, M. · Kersten, S.
Keywords: Biology · Biomedical Research · Biochemistry · Biological membranes · Blood · Precipitation (chemical) · RNA · Tissue · Adipose tissue · Blood plasma · Fasting induced adipose factors · Immunoprecipitation · Proteins · Cytokine · Fasting induced adipose factor · Fenofibrate · Messenger RNA · Peroxisome proliferator activated receptor alpha · Peroxisome proliferator activated receptor delta · Peroxisome proliferator activated receptor gamma · Unclassified drug · Adiponectin · ANGPTL4 protein, human · cell receptor · protein · RNA · Signal peptide · Transcription factor · Adipocyte · Animal cell · Blood level · Body mass · Cell differentiation · Chromatin · Controlled study · DNA responsive element · Gene control · Hepatoma cell · Human · Human cell · Human tissue · Immunoprecipitation · Intron · Liver · Mouse · Nonhuman · Rat · Transactivation · Upregulation · White adipose tissue · Animal · Blood · C57BL mouse · Cell culture · Cell line · Cell strain 3T3 · Genetic transcription · Metabolism · Molecular genetics · Nucleotide sequence · Reverse transcription polymerase chain reaction · Serodiagnosis · Tumor cell line · Western blotting · Animalia · Eukaryota · 3T3-L1 Cells · Adipocytes · Adiponectin · Adipose Tissue · Animals · Base Sequence · Blotting, Western · Cell Differentiation · Cell Line · Cell Line, Tumor · Cells, Cultured · Chromatin · Cytokines · Humans · Intercellular Signaling Peptides and Proteins · Introns · Liver · Mice · Mice, Inbred C57BL · Molecular Sequence Data · Precipitin Tests · Procetofen · Proteins · Rats · Receptors, Cytoplasmic and Nuclear · Reverse Transcriptase Polymerase Chain Reaction · RNA · RNA, Messenger · Trans-Activation (Genetics) · Transcription Factors · Transcription, Genetic · Up-Regulation
[PDF] [Abstract]

11 Differential modulation by Akkermansia muciniphila and faecalibacterium prausnitzii of host peripheral lipid metabolism and histone acetylation in mouse gut organoids
article 2014    
Author: Lukovac, S. · Belzer, C. · Pellis, L. · Keijser, B.J. · Vos, W.M. de · Montijn, R.C. · Roeselers, G.
Keywords: Biology · G protein coupled receptor 43 · Histone deacetylase · Membrane protein · Peroxisome proliferator activated receptor gamma · Protein Fiaf · Short chain fatty acid · Unclassified drug · Adult · Animal experiment · Animal tissue · Bacterial strain · Cell cycle regulation · Cell metabolism · Controlled study · Down regulation · Epigenetics · Ex vivo study · Fiaf gene · Gene · Gene control · Gene expression · Gene silencing · Gpr43 gene · Hdac3 gene · Hdac5 gene · Histone acetylation · Host pathogen interaction · Ileum · In vivo study · Intestine flora · Lipid metabolism · Lipolysis · Male · Mouse · Nonhuman · Nucleotide sequence · Ppargamma gene · Satiety · Transcription regulation · Akkermansia muciniphila · Faecalibacterium prausnitzii · Biomedical Innovation · Healthy Living · Life · MSB - Microbiology and Systems Biology · ELSS - Earth, Life and Social Sciences
[Abstract]

12 Salsalate attenuates diet induced non-alcoholic steatohepatitis in mice by decreasing lipogenic and inflammatory processes
article 2015    
Author: Liang, W. · Verschuren, L. · Mulder, P. · Hoorn, J.W.A. van der · Verheij, J. · Dam, A.D. van · Boon, M.R. · Princen, H.M.G. · Havekes, L.M. · Kleemann, R. · Hoek, A.M. van den
Keywords: Biology · Alanine aminotransferase · Aspartate aminotransferase · Glucose · High density lipoprotein cholesterol · Insulin · Interleukin 6 · Low density lipoprotein cholesterol · Peroxisome proliferator activated receptor alpha · Salsalate · Triacylglycerol · Alanine aminotransferase blood level · Animal cell · Animal experiment · Animal model · Animal tissue · Aspartate aminotransferase blood level · Body weight · Controlled study · Down regulation · Drug efficacy · Drug response · Dyslipidemia · Energy metabolism · Fatty acid oxidation · Fatty liver · Gene expression · Glucose blood level · Glycemic control · Hepatitis · Insulin blood level · Insulin resistance · Lipid metabolism · Lipogenesis · Male · Mouse · Nonalcoholic fatty liver · Nonhuman · Treatment duration · Treatment outcome · Triacylglycerol blood level · Upregulation · Weight gain · Biomedical Innovation · Healthy Living · Life · MSB - Microbiology and Systems Biology MHR - Metabolic Health Research · ELSS - Earth, Life and Social Sciences
[Abstract]

13 Integrative Biological Analysis of the APOE*3-Leiden Transgenic Mouse
article 2004    
Author: Clish, C.B. · Davidov, E. · Oresic, M. · Plasterer, T.N. · Lavine, G. · Londo, T. · Meys, M. · Snell, P. · Stochaj, W. · Adourian, A. · Zhang, X. · Morel, N. · Neumann, E. · Verheij, E. · Vogels, J.T.W.E. · Havekes, L.M. · Afeyan, N. · Regnier, F. · Greef, J. van der · Naylor, S.
Keywords: Biology Pharmacology · Analytical research · Biomedical research · DNA · Fatty acid binding protein · Lipid · Liver protein · Lysophosphatidylcholine · Messenger RNA · Peroxisome proliferator activated receptor alpha · Protein · Triacylglycerol · Animal model · Animal tissue · Controlled study · Gene · Gene expression · High performance liquid chromatography · Mass spectrometry · Mouse · Nonhuman · Principal component analysis · Transgenic mouse · Animals · Apolipoprotein E3 · Apolipoproteins E · Arteriosclerosis · Carrier Proteins · Chromatography, High Pressure Liquid · Chromatography, Liquid · Fatty Acid-Binding Proteins · Genome · Humans · Lipid Metabolism · Liver · Lysophosphatidylcholines · Mass Spectrometry · Mice · Mice, Transgenic · Models, Biological · Multivariate Analysis · Oligonucleotide Array Sequence Analysis · Receptors, Cytoplasmic and Nuclear · RNA · RNA, Messenger · Transcription Factors · Trypsin · Animalia · Mammalia · Mus musculus
[Abstract]

14 Moderate alcohol consumption increases insulin sensitivity and ADIPOQ expression in postmenopausal women: A randomised, crossover trial
article 2008    
Author: Joosten, M.M. · Beulens, J.W.J. · Kersten, S. · Hendriks, H.F.J.
Keywords: Biomedical Research · Adiponectin · Alcohol consumption · Gene expression · High molecular weight adiponectin · Insulin sensitivity · Lipid profile · Peroxisome proliferator-activated receptor gamma · Postmenopausal women · Alcohol · Low density lipoprotein cholesterol · Messenger RNA · Adiponectin gene · Adult · Alcohol consumption · Body mass · Cholesterol blood level · Controlled study · Correlation analysis · Gene · Gene expression · Grape juice · Homeostasis · Human experiment · Insulin resistance · Insulin sensitivity · Netherlands · Postmenopause · Protein blood level · Protein expression · Real time polymerase chain reaction · Statistical significance · Subcutaneous fat · Wine · Adiponectin · Alcohol Drinking · Cross-Over Studies · Female · Gene Expression Regulation · Humans · Insulin · Lipids · Middle Aged · Postmenopause · PPAR gamma · Random Allocation · Food and Nutrition · Healthy Living
[PDF] [Abstract]

15 Transcriptome and proteome profiling of colon mucosa from quercetin fed F344 rats point to tumor preventive mechanisms, increased mitochondrial fatty acid degradation and decreased glycolysis
article 2008    
Author: Dihal, A.A. · Woude, H. van der · Hendriksen, P.J.M. · Charif, H. · Dekker, L.J. · IJsselstijn, L. · Boer, V.C.J. de · Alink, G.M. · Burgers, P.C. · Rietjens, I.M.C.M. · Woutersen, R.A. · Stierum, R.H.
Keywords: Biology · Toxicology and Applied Pharmacology · Biomarker · Colorectal cancer · Quercetin · Transcriptomics · fatty acid · glutathione peroxidase 2 · heat shock protein · mitogen activated protein kinase · peroxisome proliferator activated receptor alpha · quercetin · transcriptome · animal experiment · animal model · article · cancer prevention · cell cycle · colon mucosa · colorectal cancer · controlled study · down regulation · energy metabolism · Fischer 344 rat · gene expression · gene targeting · genetic analysis · glycolysis · lipid degradation · male · nonhuman · nucleotide sequence · priority journal · proteomics · rat · statistical significance · tumor biopsy · Animals · Colon · Colorectal Neoplasms · Diet · Down-Regulation · Fatty Acids · Gene Expression Profiling · Glycolysis · Intestinal Mucosa · Male · Mitochondria · Proteome · Quercetin · Rats · Rats, Inbred F344 · Rattus
[Abstract]

16 Species differences in hepatic peroxisome proliferation, cell replication and transforming growth factor-β1 gene expression in the rat, Syrian hamster and guinea pig
article 2000    
Author: Lake, B.G. · Rumsby, P.C. · Price, R.J. · Cunninghame, M.E.
Keywords: Hepatic peroxisome proliferation · Replicative DNA synthesis · Species differences · Syrian hamster · Transforming growth factor-β1 · ciprofibrate · messenger RNA · methylclofenapate · peroxisome proliferator · peroxisome proliferator activated receptor · pirinixic acid · somatomedin B receptor · transforming growth factor beta1 · animal model · animal tissue · cell division · controlled study · DNA synthesis · enzyme activity · fatty acid oxidation · liver weight · nonhuman · species difference · Syrian hamster · Animals · Cell Division · Clofenapate · Clofibric Acid · Cricetinae · DNA · Gene Expression · Guinea Pigs · Liver · Male · Mesocricetus · Molecular Structure · Organ Size · Peroxisome Proliferators · Pyrimidines · Rats · Rats, Sprague-Dawley · Receptor, IGF Type 2 · Species Specificity · Transforming Growth Factor beta · Cavia · Cavia porcellus · Cricetinae · Mesocricetus auratus · Rodentia · Sus scrofa · Zea mays
[Abstract]

17 Studies on the mechanism of fibrate-inhibited expression of plasminogen activator inhibitor-1 in cultured hepatocytes from cynomolgus monkey
article 1997    
Author: Arts, J. · Kooistra, T.
Keywords: Biology · 9-cis retinoic acid · fibrates · hepatocytes · peroxisome proliferator-activated receptor · plasminogen activator inhibitor-1 · 2 [1 (3 amidinothiopropyl) 1h indol 3 yl] 3 (1 methyl 1h indol 3 yl)maleimide · alitretinoin · antilipemic agent · epidermal growth factor · fibric acid derivative · gemfibrozil · peroxisome proliferator · phorbol 13 acetate 12 myristate · plasminogen activator inhibitor 1 · protein kinase C · protein kinase C inhibitor · retinoid X receptor · transforming growth factor beta · animal cell · controlled study · dose time effect relation · drug mechanism · enzyme activity · gene expression · hyperlipidemia · liver cell culture · monkey · nonhuman · Animals · Antilipemic Agents · Cells, Cultured · Dose-Response Relationship, Drug · Liver · Macaca fascicularis · Plasminogen Activator Inhibitor 1 · RNA, Messenger
[Abstract]

18 Leptin deficiency unmasks the deleterious effects of impaired peroxisome proliferator-activated receptor γ function (P465L PPARγ) in mice
article 2006    
Author: Gray, S.L. · Dalla Nora, E. · Grosse, J. · Manieri, M. · Stoeger, T. · Medina-Gomez, G. · Burling, K. · Wattler, S. · Russ, A. · Yeo, G.S.H. · Chatterjee, V.K. · O'Rahilly, S. · Voshol, P.J. · Cinti, S. · Vidal-Puig, A.
Keywords: Biology · Peroxisome proliferator activated receptor gamma · Adipose tissue · Animal cell · Animal experiment · Animal model · Animal tissue · Carbohydrate metabolism · Controlled study · Energy balance · Female · Gene expression · gene mutation · Homozygosity · Hyperphagia · Insulin resistance · Insulin sensitivity · Lipid metabolism · Lipid storage · Lipogenesis · Male · Metabolic disorder · Nonhuman · Obesity · Point mutation · Protein deficiency · Protein function · Tissue distribution · Tissue expansion · Blood · Genetics · Glucose blood level · Homozygote · Lethal gene · Metabolism · Mouse mutant · Pathology · Physiology · Adipose Tissue · Animals · Blood Glucose · Gene Expression Profiling · Genes, Lethal · Homozygote · Insulin · Insulin Resistance · Leptin · Lipid Metabolism · Mice · Mice, Obese · PPAR gamma
[Abstract]

19 Mouse models for atherosclerosis and pharmaceutical modifiers
article 2007    
Author: Zadelaar, A.S.M. · Kleemann, R. · Verschuren, L. · Vries-van der Weij, J. de · Hoorn, J. van der · Princen, H.M. · Kooistra, T.
Keywords: Biology · Biomedical Research · ACE inhibitors · AT1 receptor antagonists · Atherosclerosis · LXR · Mouse models · Pharmaceutical drugs · PPAR · Statins · atorvastatin · avasimibe · candesartan · captopril · cholesterol acyltransferase inhibitor · dipeptidyl carboxypeptidase inhibitor · hydralazine · hydroxymethylglutaryl coenzyme A reductase inhibitor · irbesartan · losartan · ly 465608 · n (2,2,2 trifluoroethyl) n [4 [2,2,2 trifluoro 1 hydroxy 1 (trifluoromethoxy)ethyl]phenyl]benzenesulfonamide · olmesartan · perindopril · peroxisome proliferator activated receptor alpha agonist · pirinixic acid · pitavastatin · pravastatin · quinapril · ramipril · rosuvastatin · simvastatin · telmisartan · temocapril · unindexed drug · valsartan · zofenopril · antihypertensive agent · antilipemic agent · apolipoprotein E · atherosclerosis · pathophysiology · sensitivity and specificity · Animals · Antihypertensive Agents · Antilipemic Agents · Apolipoproteins E · Atherosclerosis · Disease Models, Animal · Dose-Response Relationship, Drug · Drug Administration Schedule · Dyslipidemias · Humans · Hydroxymethylglutaryl-CoA Reductase Inhibitors · Hypertension · Male · Mice · Mice, Knockout · Mice, Transgenic · Sensitivity and Specificity
[Abstract]

20 cAMP-dependent signaling regulates the adipogenic effect of n-6 polyunsaturated fatty acids
article 2008    
Author: Madsen, L. · Pedersen, L.M. · Liaset, B. · Ma, T. · Petersen, R.K. · Berg, S. van den · Pan, J. · Müller-Decker, K.M. · Dülsner, E.D. · Kleemann, R. · Kooistra, T. · Døskeland, S.O. · Kristiansen, K.
Keywords: Acids · Biomolecules · Carbohydrates · Cell culture · Cytology · Ecology · Fetal monitoring · Metabolism · Organic compounds · Oxygen · Urea · Adipogenesis · Cyclooxygenase · Demanding processes · Gluconeogenesis · Heat productions · Hepatic expressions · High protein diets · In vitro · Oxygen consumptions · Peroxisome proliferator- activated receptors · Polyunsaturated fatty acids · Prostaglandin synthesis · Protein kinases · Urea syntheses · Nutrition · Cyclic AMP dependent protein kinase · Glucagon · Glucose · Insulin · Omega 6 fatty acid · Peroxisome proliferator activated receptor gamma coactivator 1alpha · Prostaglandin synthase · Urea · Carbohydrate · Unsaturated fatty acid · Adipocyte · Adipogenesis · Amino acid sequence · Animal cell · Animal cell culture · Animal experiment · Animal model · Animal tissue · Carbohydrate diet · Controlled study · Energy conservation · Enzyme activity · Enzyme induction · Gluconeogenesis · In vitro study · In vivo study · Nonhuman · Prostaglandin synthesis · Protein diet · Protein expression · Signal transduction · Urea cycle · Biological model · C57BL mouse · Cell strain 3T3 · Chemistry · Cytology · Genetics · Mus · 3T3-L1 Cells · Adipocytes · Adipogenesis · Animals · Carbohydrates · Cyclic AMP · Fatty Acids, Omega-6 · Fatty Acids, Unsaturated · Male · Mice · Mice, Inbred C57BL · Models, Biological · Obesity · Signal Transduction · Urea · Healthy for Life · Healthy Living
[PDF] [Abstract]

Search results also available in MS Excel format.

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