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Showing 1 to 8 of 8 found. | Sort by date

1 Genomics and systems biology - How relevant are the developments to veterinary pharmacology, toxicology and therapeutics?
article 2005    
Author: Witkamp, R.F.
Keywords: Health · Biomedical Research · messenger RNA · protein · analytic method · data analysis · data base · DNA microarray · DNA sequence · gas chromatography · genomics · liquid chromatography · mass spectrometry · medical research · metabolite · metabolomics · nuclear magnetic resonance · priority journal · proteomics · review · transcriptomics · veterinary medicine · Animals · Genomics · Pharmaceutical Preparations · Proteomics · Veterinary Drugs · Animalia · PharmacologyToxicology
[Abstract]

2 The introduction of toxicogenomics; potential new markers of hepatotoxicity.
article 2005    
Author: Heijne, W.H. · Stierum, R.H. · Leeman, W.R. · Ommen, B. van
Keywords: Toxicology · Physiological Sciences · biological marker · drug · animal · biological model · chemically induced disorder · drug toxicity · gene expression profiling · genetics · human · liver disease · methodology · review · toxicogenetics · toxicology · Animals · Biological Markers · Drug Toxicity · Gene Expression Profiling · Humans · Liver Diseases · Models, Biological · Pharmaceutical Preparations · Toxicogenetics · Toxicology

3 4-Week oral toxicity study of a combination of eight chemicals in rats: Comparison with the toxicity of the individual compounds
article 1990    
Author: Jonker, D. · Woutersen, R.A. · Bladeren, P.J. van · Til, H.P. · Feron, V.J.
Keywords: dioctyltin dichloride · hemoglobin · loperamide · lysinoalanine · metaldehyde · mirex · potassium nitrite · sodium metabisulfite · stannous chloride · unclassified drug · animal experiment · article · drug mixture · female · kidney mass · male · nonhuman · priority journal · rat · toxicity · Administration, Oral · Animal · Blood · Body Weight · Drug Synergism · Drug Toxicity · Eating · Female · Male · Organ Weight · Pharmaceutical Preparations · Rats · Rats, Inbred Strains · Support, Non-U.S. Gov't · Animalia · Rattus norvegicus
[Abstract]

4 Generic solid phase extraction-liquid chromatography-tandem mass spectrometry method for fast determination of drugs in biological fluids
article 2003    
Author: Schellen, A. · Ooms, B. · Lagemaat, D. van de · Vreeken, R. · Dongen, W.D. van
Keywords: Drugs Pharmacology · Analytical research · Drug analysis · Generic method · Body fluids · Drug products · Mass spectrometers · Solid phase extraction · High performance liquid chromatography · caffeine · carbamazepine · paclitaxel · paracetamol · procainamide · propranolol · ranitidine · sulfadiazine · sulfamerazine · theobromine · theophylline · accuracy · article · controlled study · drug blood level · drug determination · high performance liquid chromatography · human · linear system · physical chemistry · priority journal · quantitative analysis · solid phase extraction · tandem mass spectrometry · technique · time · Chromatography, High Pressure Liquid · Humans · Mass Spectrometry · Pharmaceutical Preparations · Reproducibility of Results · Sensitivity and Specificity · Spectrophotometry, Ultraviolet
[Abstract]

5 Prediction of interindividual variation in drug plasma levels in vivo from individual enzyme kinetic data and physiologically based pharmacokinetic modeling
article 2000    
Author: Bogaards, J.J.P. · Hissink, E.M. · Briggs, M. · Weaver, R. · Jochemsen, R. · Jackson, P. · Bertrand, M. · Bladeren, P. van
Keywords: Nutrition · Cytochrome P450 · Interindividual variation · Metabolism · Physiologically based pharmacokinetic modeling · Agomelatine · Bufuralol · Chlorzoxazone · Coumarin · Cytochrome P450 · Diclofenac · Ethoxyresorufin · Mephenytoin · Testosterone · Clinical trial · Controlled clinical trial · Controlled study · Drug blood level · Enzyme kinetics · Food drug interaction · Genetic polymorphism · Human · Human cell · Human experiment · Human tissue · Liver microsome · Male · Model · Normal human · Phase 1 clinical trial · Phenotype · Priority journal · Acetamides · Cell Line · Cytochrome P-450 Enzyme System · Humans · Hypnotics and Sedatives · Isoenzymes · Kinetics · Microsomes, Liver · Models, Biological · Pharmaceutical Preparations · Pharmacokinetics · Recombinant Proteins · Transfection
[Abstract]

6 Review on the toxicity of ethylmercury including its presence as a preservative in biological and pharmaceutical products
article 2001    
Author: Magos, L.
Keywords: Toxicology · Biological preparations · Clinical studies · Dietary exposure · Ethylmercury · Kinetics · Methylmercury · Occupational exposure · Thimerosal · Ethylmercury derivative · Methylmercury · Natural product · Thiomersal · Acrodynia · Adolescent · Adult · Aged · Blood brain barrier · Child · Clinical article · Contact allergy · Decomposition · Female · Human · Intoxication · Neurotoxicology · Occupational exposure · Protein losing gastroenteropathy · Review · Toxicity testing · Animals · Biological Products · Environmental Exposure · Ethylmercury Compounds · Food Additives · Food Contamination · Humans · Mercury Poisoning · Nervous System Diseases · Occupational Exposure · Pharmaceutical Preparations · Preservatives, Pharmaceutical · Thimerosal
[Abstract]

7 Systems biology, connectivity and the future of medicine
article 2005    
Author: Greef, J. van der
Keywords: Biology · Analytical research · Disease progression · Disease system fingerprints · Diseases · Drug perturbations · Drugs · Medicine · Patient treatment · Reversed-pharmacology · Systems biology · Systems pathology · Systems pharmacology · Systems-based combinatorial-therapies approach · Biology · Diseases · Drug therapy · Pathology · Pharmacokinetics · Disease system fingerprints · Pharmacology · Systems biology · Drug products · amlodipine plus atorvastatin · berberine · biological marker · fluticasone propionate plus salmeterol · ginseng extract · glibenclamide plus metformin · article · asthma · bioinformatics · biostatistics · cardiovascular disease · clinical protocol · disease course · drug design · drug industry · drug research · human · hypercholesterolemia · in vivo study · medicine · metabolic syndrome X · methodology · molecular biology · non insulin dependent diabetes mellitus · nonhuman · quality control · quality of life · Cell Physiology · Drug Design · Models, Biological · Pharmaceutical Preparations · Pharmacology · Pharmacology, Clinical · Systems Biology · Panax ginseng
[Abstract]

8 Pediatric Mïcrodose and Microtracer Studies Using 14C in Europe
article 2015    
Author: Turner, M.A. · Mooij, M.G. · Vaes, W.H.J. · Windhorst, A.D. · Hendrikse, N.H. · Knibbe, C.A.J. · Körgvee, L.T. · Maruszak, W. · Grynkiewicz, G. · Garner, R.C. · Tibbocl, D. · Park, B.K. · Wildt, S.N. de
Keywords: Nutrition · Carbon · Drug · Age · Dose calculation · Dose response · Drug-Related Side Effects and Adverse Reactions · Economics · Ethics · Legislation and jurisprudence · Metabolism · Newborn · Phase 1 clinical trial (topic) · Preschool child · Age Factors · Carbon Radioisotopes · Child · Child, Preschool · Clinical Trials, Phase I as Topic · Dose-Response Relationship, Drug · Drug Approval · Drug Costs · Drug Dosage Calculations · Drug-Related Side Effects and Adverse Reactions · Europe · Government Regulation · Humans · Infant · Infant, Newborn · Patient Safety · Pharmaceutical Preparations · Pharmacokinetics · Risk Assessment · Risk Factors · Food and Nutrition · Healthy Living · Life · MSB - Microbiology and Systems Biology · ELSS - Earth, Life and Social Sciences
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 8 of 8 found. | Sort by date