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1 Purification of the stress protein αB-crystallin and its differentially phosphorylated forms
article 1998    
Author: Noort, J.M. van · Veelen, P. van · Hopstaken, F.
Keywords: Animals · Cattle · Chromatography, Gel · Chromatography, High Pressure Liquid · Chromatography, Ion Exchange · Crystallins · Lens, Crystalline · Mass Spectrometry · Phosphorylation · Bovinae · Rodentia
[Abstract]

2 Identification of multiple post-translational modifications in the porcine brain specific p25α
article 2008    
Author: Kleinnijenhuis, A.J. · Hedegaard, C. · Lundvig, D. · Sundbye, S. · Issinger, O.G. · Jensen, O.N. · Jensen, P.H.
Keywords: Biology · Citrullination · Methylation · O-glycosylation · Oligodendrocyte · P25α · Phosphorylation · phosphoprotein · protein p25alpha · unclassified drug · nerve protein · amino acid sequence · animal tissue · article · brain · liquid chromatography · methylation · nonhuman · priority journal · protein analysis · protein phosphorylation · swine · tandem mass spectrometry · translation regulation · animal · chromosome map · genetics · metabolism · methodology · molecular cloning · molecular genetics · mutation · phosphorylation · physiology · protein processing · Sus · Animals · Brain · Chromosome Mapping · Cloning, Molecular · Molecular Sequence Data · Mutation · Nerve Tissue Proteins · Phosphorylation · Protein Processing, Post-Translational · Swine · Tandem Mass Spectrometry · Healthy for Life · Healthy Living
[Abstract]

3 14-3-3 Proteins and a 13-lipoxygenase form associations in a phosphorylation-dependent manner
article 2000    
Author: Holtman, W.L. · Roberts, M.R. · Wang, M.
Keywords: Lipid metabolism · Protein interactions · lipoxygenase · M protein · barley · conference paper · dephosphorylation · embryo · gel filtration · germination · molecular weight · priority journal · protein interaction · protein phosphorylation · reversed phase high performance liquid chromatography · surface plasmon resonance · 14-3-3 Proteins · Blotting, Western · Chromatography, Gel · Electrophoresis, Polyacrylamide Gel · Hordeum · Lipoxygenase · Phosphorylation · Protein Binding · Seeds · Tyrosine 3-Monooxygenase · Hordeum vulgare subsp. vulgare
[Abstract]

4 T cells discriminate between differentially phosphorylated forms of αB-crystallin, a major central nervous system myelin antigen
article 1998    
Author: Stipdonk, M.J.B. van · Willems, A.A. · Amor, S. · Persoon-Deen, C. · Travers, P.J. · Boog, C.J.P. · Noort, J.M. van
Keywords: Health · αB-crystallin · Epitope analysis · Heal shock protein · I-A(s) binding motif · Phosphorylation · Post-translational modification · TCR · Amino Acid Sequence · Animals · Binding Sites · Cattle · Computer Simulation · Crystallins · Epitopes · Female · Lymphocyte Activation · Mice · Mice, Inbred Strains · Models, Molecular · Molecular Sequence Data · Phosphorylation · Receptors, Antigen, T-Cell · Serine · T-Lymphocytes
[Abstract]

5 Endothelial permeability for macromolecules: Mechanistic aspects of pathophysiological modulation
article 1997    
Author: Hinsbergh, V.W.M. van
Keywords: Actins · Animals · Base Sequence · Blood Proteins · Calcium · Capillary Permeability · Cyclic AMP · Cyclic GMP · Endothelium, Vascular · Humans · Intercellular Junctions · Macromolecular Substances · Molecular Sequence Data · Myosin-Light-Chain Kinase · Myosins · Nitric Oxide · Permeability · Phosphoprotein Phosphatase · Phosphorylation

6 A 16-Residue Peptide Fragment of Macrophage Migration Inhibitory Factor, MIF-(50-65), Exhibits Redox Activity and Has MIF-like Biological Functions
article 2003    
Author: Nguyen, M.T. · Beck, J. · Lue, H. · Fünfzig, H. · Kleemann, R. · Koolwijk, P. · Kapurniotu, A. · Bernhagen, J.
Keywords: Biology · Biomedical Research · Cells · Conformations · Enzymes · Molecular biology · Redox reactions · Phosphorylation · Biochemistry · Animalia · 3T3 Cells · Amino Acid Motifs · Amino Acid Sequence · Animals · Biotinylation · Catalysis · Cell Cycle Proteins · Cell Division · Cells, Cultured · Chromatography, High Pressure Liquid · Circular Dichroism · Cyclin-Dependent Kinase Inhibitor p27 · Cysteine · Disulfides · Endocytosis · Endothelium, Vascular · Glutathione · Humans · Inflammation · Kinetics · Macrophage Migration-Inhibitory Factors · Mass Spectrometry · Mice · Mitogen-Activated Protein Kinase 1 · Mitogen-Activated Protein Kinase 3 · Mitogen-Activated Protein Kinases · Molecular Sequence Data · Oxidation-Reduction · Oxygen · Peptides · Phosphorylation · Protein Binding · Protein Conformation · Serine · Signal Transduction · Sulfhydryl Compounds · Time Factors · Tumor Suppressor Proteins
[PDF] [Abstract]

7 Retrospective detection of exposure to organophosphorus anti-cholinesterases: Mass spectrometric analysis of phosphylated human butyrylcholinesterase
article 2002    
Author: Fidder, A. · Hulst, A.G. · Noort, D. · Ruiter, R. de · Schans, M.J. van der · Benschop, H.P. · Langenberg, J.P.
Keywords: Warfare · Cholinesterase · Cholinesterase inhibitor · Nerve gas · Organophosphorus compound · Pronase · Sarin · Article · Colorimetry · Enzyme activity · Enzyme assay · High performance liquid chromatography · Hydrolysis · Intoxication · Mass spectrometry · Protein phosphorylation · Spectrometry · Synthesis · Butyrylcholinesterase · Cholinesterase Inhibitors · Environmental Exposure · Environmental Monitoring · Humans · Insecticides · Peptide Fragments · Sarin · Spectrometry, Mass, Electrospray Ionization · Terrorism · Butyrylcholinesterase, EC 3.1.1.- · Cholinesterase Inhibitors · Insecticides · Peptide fragments · Sarin, 107-44-8
[Abstract]

8 Simultaneous determination of endogenous deoxynucleotides and phosphorylated nucleoside reverse transcriptase inhibitors in peripheral blood mononuclear cells using ion-pair liquid chromatography coupled to mass spectrometry
article 2008    
Author: Coulier, L. · Kampen, J.J.A. van · Groot, R. de · Gerritsen, H.W. · Bas, R.C. · Dongen, W.D. van · Brüll, L.P. · Luider, T.M.
Keywords: Biology · Analytical research · HIV · Intracellular · Ion-pair · Nucleoside reverse transcriptase inhibitor · Nucleotide · abacavir · carbovir · stavudine · tenofovir · zidovudine · cell lysate · controlled study · drug cell level · human cell · ion pair chromatography · isolation procedure · performance measurement system · peripheral blood mononuclear cell · protein phosphorylation · quadrupole mass spectrometry · separation technique
[Abstract]

9 Filamentous fungi as production organisms for glycoproteins of bio-medical interest
article 1999    
Author: Maras, M. · Die, I. van · Contreras, R. · Hondel, C.A.M.J.J. van den
Keywords: Filamentous fungi · Homologous and heterologous protein secretion · N-glycosylation · O-glycosylation · Phosphorylation · Protein-linked carbohydrates · Carbohydrate · Fungal protein · Glycan · Glycoprotein · Mannose · Recombinant protein · Drug industry · Fungus · Gene fusion · Genetic engineering · Nonhuman · Priority journal · Protein secretion · Protein synthesis · Review · Biotechnology · Carbohydrate Sequence · Fungi · Glycoproteins · Glycosylation · Humans · Molecular Sequence Data · Oligosaccharides · Protein Engineering · Recombinant Proteins · Fungi · Mammalia
[Abstract]

10 Role of RhoA and Rho kinase in lysophosphatidic acid-induced endothelial barrier dysfunction.
article 2000    
Author: Nieuw Amerongen, G.P. van · Vermeer, M.A. · Hinsbergh, V.W. van
Keywords: Biology · Amides · Calcium · Cell Membrane Permeability · Cells, Cultured · Cyclic AMP · Cytoskeleton · Dose-Response Relationship, Drug · Endothelium, Vascular · Enzyme Activation · Enzyme Inhibitors · Horseradish Peroxidase · Humans · Intracellular Signaling Peptides and Proteins · Myosin Light Chains · Phosphatidic Acids · Phosphorylation · Protein-Serine-Threonine Kinases · Pyridines · rhoA GTP-Binding Protein · Thrombin · Time Factors · Umbilical Veins
[Abstract]

11 Activation of rhoa by thrombin in endothelial hyperpermeability: Role of rho kinase and protein tyrosine kinases
article 2000    
Author: Nieuw Amerongen, G.P. van · Delft, S.V. · Vermeer, M.A. · Collard, J.G. · Hinsbergh, V.W.M. van
Keywords: Amides · Calcium · Cell Membrane Permeability · Cells, Cultured · Cytoskeleton · Endothelium, Vascular · Enzyme Activation · Enzyme Inhibitors · Hemostatics · Humans · Intracellular Signaling Peptides and Proteins · Myosin Light Chains · Phosphorylation · Protein Binding · Protein-Serine-Threonine Kinases · Protein-Tyrosine Kinases · Proto-Oncogene Proteins c-akt · Pyridines · rhoA GTP-Binding Protein · Thrombin · Umbilical Veins
[Abstract]

12 Direct determination of the chemical composition of acetylcholinesterase phosphonylation products utilizing electrospray-ionization mass spectrometry
article 1997    
Author: Barak, R. · Ordentlich, A. · Barak, D. · Fischer, M. · Benschop, H.P. · Jong, L.P.A. de · Segall, Y. · Velan, B. · Shafferman, A.
Keywords: Determination · Chemical compounds · Acetylcholinesterase · Electrospray · Mass spectroscopy · Ionization · Aging (biology) · Inhibitors · Organic phosphates · Acetylcholinesterase, EC 3.1.1.7 · Cholinesterase Inhibitors · Organophosphorus Compounds · Recombinant Proteins · Acetylcholinesterase · Aging · ESI-MS · Organophosphonate inhibitor · Enzyme activity · Enzyme phosphorylation · Mass spectrometry · Alkylation · Cholinesterase inhibitors · Humans · Mass spectrometry · Molecular structure · Molecular weight · Organophosphorus compounds · Recombinant proteins
[PDF] [Abstract]

13 14-3-3 proteins interact with a 13-lipoxygenase, but not with a 9-lipoxygenase
article 2000    
Author: Holtman, W.L. · Roberts, M.R. · Oppedijk, B.J. · Testerink, C. · Zeijl, M.J. van · Wang, M.
Keywords: Interaction · 13 lipoxygenase · 9 lipoxygenase · lipoxygenase · unclassified drug · barley · enzyme purification · enzyme substrate complex · germination · immunoprecipitation · nucleotide sequence · protein family · protein phosphorylation · surface plasmon resonance · Western blotting · 14-3-3 Proteins · Antibodies, Monoclonal · Chemistry, Physical · Escherichia coli · Hordeum · Immunosorbent Techniques · Isoenzymes · Lipoxygenase · Proteins · Recombinant Proteins · Surface Plasmon Resonance · Tyrosine 3-Monooxygenase · Hordeum vulgare subsp. vulgare
[PDF] [Abstract]

14 Expression of cGMP-dependent protein kinase I and phosphorylation of its substrate, vasodilator-stimulated phosphoprotein, in human endothelial cells of different origin
article 1995    
Author: Draijer, R. · Vaandrager, A.B. · Nolte, C. · Jonge, H.R. de · Walter, U. · Hinsbergh, V.W.M. van
Keywords: Biology · aortic endothelial cells · cGMP · endothelial contraction · microvascular endothelial cells · permeability · 8 (4 chlorophenylthio) cyclic GMP · calcium ion · cyclic GMP · cyclic GMP derivative · fura 2 · horseradish peroxidase · phosphoprotein · protein kinase · thrombin · unclassified drug · vasodilator stimulated phosphoprotein · aorta · article · calcium cell level · cell membrane permeability · endothelium cell · human · human cell · iliac artery · iliac vein · prepuce · priority journal · protein phosphorylation · umbilical vein · vascular endothelium · Aorta · Autoradiography · Blotting, Northern · Calcium Channels · Capillary Permeability · Cell Adhesion Molecules · Cells, Cultured · Comparative Study · Cyclic GMP · Cyclic GMP-Dependent Protein Kinases · Cytoplasm · Endothelium, Vascular · Enzyme Activation · Hemostasis · Human · Iliac Artery · Iliac Vein · Immunohistochemistry · Microcirculation · Microfilament Proteins · Models, Biological · Phosphoproteins · Phosphorylation · Platelet Aggregation Inhibitors · RNA · Support, Non-U.S. Gov't · Thionucleotides · Thrombin · Time Factors · Umbilical Veins
[Abstract]

15 Sustained activation of the mammalian target of rapamycin nutrient sensing pathway is associated with hepatic insulin resistance, but not with steatosis, in mice
article 2006    
Author: Korsheninnikova, E. · Zon, G.C.M. van der · Voshol, P.J. · Janssen, G.M. · Havekes, L.M. · Grefhorst, A. · Kuipers, F. · Reijngoud, D.-J. · Romijn, J.A. · Ouwens, D.M. · Maassen, J.A.
Keywords: Biology · Biomedical Research · Hepatic steatosis · High-fat feeding · Nutrient sensing · Enzyme inhibitor · Glucose · Hydroxymethylglutaryl coenzyme A reductase kinase · Mammalian target of rapamycin · Protein kinase B · Protein S6 · S6 kinase · Tetradecylglycidic acid · Unclassified drug · Animal experiment · Animal model · Animal tissue · Controlled study · Diabetic obesity · Diabetogenesis · Enzyme activation · Glucose clamp technique · Hyperinsulinemia · Insulin resistance · Lipid diet · Liver homogenate · Liver mitochondrion · Mitochondrial membrane · Nonhuman · Nutrient concentration · Nutrient content · Protein blood level · Protein induction · Protein phosphorylation · Protein synthesis · Protein targeting · Species comparison · 1-Phosphatidylinositol 3-Kinase · Animals · Blood Glucose · Dietary Fats · DNA, Mitochondrial · Electron Transport Complex IV · Fatty Acids · Fatty Liver · Insulin · Insulin Resistance · Leucine · Liver · Male · Mice · Mice, Inbred C57BL · Phosphorylation · Protein Kinases · Ribosomal Proteins
[Abstract]

16 Increased hepatic insulin sensitivity together with decreased hepatic triglyceride stores in hormone-sensitive lipase-deficient mice
article 2003    
Author: Voshol, P.J. · Haemmerle, G. · Ouwens, D.M. · Zimmermann, R. · Zechner, R. · Teusink, B. · Maassen, J.A. · Havekes, L.M. · Romijn, J.A.
Keywords: Health · Glucose · Hormone sensitive lipase · Insulin receptor · Protein kinase B · Triacylglycerol · Triacylglycerol lipase · Unclassified drug · Animal tissue · Controlled study · Enzyme activity · Enzyme deficiency · Enzyme mechanism · Enzyme phosphorylation · Fatty acid blood level · Gluconeogenesis · Glucose transport · Hormone sensitivity · Hyperinsulinemia · Insulin sensitivity · Knockout mouse · Lipid liver level · Lipolysis · Mouse · Nonhuman · Western blotting · Adiponectin · Animals · Blood Glucose · Cholesterol · Cholesterol Esterase · Fasting · Fatty Acids, Nonesterified · Glucose · Insulin · Intercellular Signaling Peptides and Proteins · Liver · Male · Mice · Mice, Knockout · Muscle, Skeletal · Proteins · Receptor, Insulin · Triglycerides
[Abstract]

17 Tolerance controls encephalitogenicity of αB-crystallin in the Lewis rat
article 2000    
Author: Stipdonk, M.J.B. van · Willems, A.A. · Plomp, A.C. · Noort, J.M. van · Boog, C.J.P.
Keywords: Health · Tolerance · Autoantigen · Crystallin · Myelin · Myelin associated glycoprotein · Allergic encephalomyelitis · Animal cell · Animal experiment · Autoimmune disease · Central nervous system · Controlled study · Immunization · Lymphocyte proliferation · Multiple sclerosis · Nonhuman · Rat strain · T lymphocyte · Animals · Autoantigens · Cattle · Crystallins · Dose-Response Relationship, Immunologic · Encephalomyelitis, Autoimmune, Experimental · Hypersensitivity, Delayed · Immune Tolerance · Immunity, Cellular · Immunodominant Epitopes · Lymphoid Tissue · Male · Mice · Organ Specificity · Peptide Fragments · Phosphorylation · Rats · Rats, Inbred Lew · Reverse Transcriptase Polymerase Chain Reaction · RNA, Messenger · Species Specificity · T-Lymphocytes
[Abstract]

18 GIT1 Mediates Thrombin Signaling in Endothelial Cells: Role in Turnover of RhoA-Type Focal Adhesions
article 2004    
Author: Nieuw Amerongen, G.P. van · Natarajan, K. · Yin, G. · Hoefen, R.J. · Osawa, M. · Haendeler, J. · Ridley, A.J. · Fujiwara, K. · Hinsbergh, V.W.M. van · Berk, B.C.
Keywords: Biology · Biomedical Research · Contractility · Endothelium · Focal adhesion kinase · Thrombin · 4 (1 aminoethyl) n (4 pyridyl)cyclohexanecarboxamide · antisense oligonucleotide · focal adhesion kinase · G protein coupled receptor kinase · G protein coupled receptor kinase interacting protein · GIT1 protein · guanosine triphosphatase · protein tyrosine kinase · Rho kinase · RhoA guanine nucleotide binding protein · thrombin · unclassified drug · vinculin · Adenovirus · animal cell · article · cell migration · cell shape · cell structure · cellular distribution · controlled study · depletion · endothelium cell · enzyme activation · enzyme metabolism · enzyme phosphorylation · enzyme substrate · focal adhesion · genetic transfection · human · human cell · membrane permeability · negative feedback · nonhuman · priority journal · protein function · protein localization · protein phosphorylation · protein protein interaction · protein transport · regulatory mechanism · signal transduction · umbilical vein · Adaptor Proteins, Signal Transducing · Amides · Animals · Aorta · Cattle · Cell Cycle Proteins · Cell Size · Cells, Cultured · Endothelial Cells · Endothelium, Vascular · Enzyme Inhibitors · Feedback, Biochemical · Focal Adhesion Kinase 1 · Focal Adhesion Protein-Tyrosine Kinases · Focal Adhesions · GTPase-Activating Proteins · Humans · Oligodeoxyribonucleotides, Antisense · Phosphoproteins · Phosphorylation · Protein Processing, Post-Translational · Protein Transport · Protein-Tyrosine Kinases · Proto-Oncogene Proteins pp60(c-src) · Pyridines · rac GTP-Binding Proteins · rhoA GTP-Binding Protein · RNA, Small Interfering · Signal Transduction · Thrombin · Transduction, Genetic · Transfection · Umbilical Veins · Vinculin
[Abstract]

19 Bace1 activity in cerebrospinal fluid and its relation to markers of ad pathology
article 2010    
Author: Mulder, S.D. · Flier, W.M. van der · Verheijen, J.H. · Mulder, C. · Scheltens, P. · Blankenstein, M.A. · Hack, C.E. · Veerhuis, R.
Keywords: Biology · Biomedical Research · Aβ<sub>-{40}Aβ</sub> · Alzheimer's disease · BACE1 activity · CSF biomarker profile · p-tau · t-tau · {42} · amyloid beta protein[1-40] · amyloid beta protein[1-42] · beta secretase · tau protein · threonine · adult · aged · Alzheimer disease · article · cerebrospinal fluid analysis · clinical article · controlled study · correlational study · enzyme activity · female · human · male · mild cognitive impairment · mini mental state examination · priority journal · protein phosphorylation · Aged · Alzheimer Disease · Amyloid beta-Protein · Amyloid Precursor Protein Secretases · Apolipoproteins E · Aspartic Acid Endopeptidases · Cognition Disorders · Enzyme-Linked Immunosorbent Assay · Female · Humans · Male · Middle Aged · Peptide Fragments · Statistics as Topic · tau Proteins
[Abstract]

20 Structure-function relationship of the human antimicrobial peptide LL-37 and LL-37 fragments in the modulation of TLR responses
article 2009    
Author: Molhoek, E.M. · Hertog, A.L. den · Vries, A.M.B.C. de · Nazmi, K. · Veerman, E.C.I. · Hartgers, F.C. · Yazdanbakhsh, M. · Bikker, F.J. · Kleij, D. van der
Keywords: Chemistry · Cathelicidins · Immunomodulation · MAP kinases · Physico-chemical properties · Bacterium lipopolysaccharide · Cathelicidin antimicrobial peptide LL 37 · Cytokine · Mitogen activated protein kinase · Mitogen activated protein kinase p38 · Toll like receptor · Toll like receptor 1 · Toll like receptor 2 · Toll like receptor 4 · Toll like receptor 5 · Toll like receptor 6 · Toll like receptor 7 · Toll like receptor 8 · Antiinflammatory activity · Antimicrobial activity · Article · Cytokine release · Human · Human cell · Hydrophobicity · Immunomodulation · Peripheral blood mononuclear cell · Priority journal · Protein phosphorylation · Structure activity relation · Amino Acid Sequence · Antimicrobial Cationic Peptides · Cells, Cultured · Chromatography, High Pressure Liquid · Circular Dichroism · Humans · Ligands · Molecular Sequence Data · Signal Transduction · Structure-Activity Relationship · Toll-Like Receptors · Bacteria (microorganisms)
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 24 found. Next | Sort by date