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Showing 1 to 12 of 12 found. | Sort by date

1 Olmesartan and pravastatin additively reduce development of atherosclerosis in APOE*3Leiden transgenic mice
article 2007    
Author: Hoorn, J.W.A. van der · Kleemann, R. · Havekes, L.M. · Kooistra, T. · Princen, H.M.G. · Jukema, J.W.
Keywords: Biology · Biomedical Research · APOE*3Leiden mice · Atherosclerosis · Combination therapy · Olmesartan · Pravastatin · T lymphocyte · transgenic mouse · Angiotensin II Type 1 Receptor Blockers · Animals · Apolipoprotein E3 · Atherosclerosis · Blood Pressure · Collagen · Diet, Atherogenic · Drug Synergism · Female · Humans · Hydroxymethylglutaryl-CoA Reductase Inhibitors · Imidazoles · Inflammation · Lipids · Macrophages · Mice · Mice, Transgenic · Monocytes · Muscle, Smooth, Vascular · Pravastatin · Recombinant Proteins · Serum Amyloid A Protein · T-Lymphocytes · Tetrazoles
[PDF] [Abstract]

2 Different effects of 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors on sterol synthesis in various human cell types
article 1995    
Author: Vliet, A.K. van · Thiel, G.C.F. van · Huisman, R.H. · Moshage, H. · Yap, S.H. · Cohen, L.H.
Keywords: Biology · HMG-CoA reductase inhibitor · Human cell · Lovastatin · Pravastatin · Simvastatin · Sterol synthesis · Transport · hydroxymethylglutaryl coenzyme a reductase inhibitor · mevinolin · pravastatin · simvastatin · controlled study · human · human cell · liver cell · priority journal · sterol synthesis · Blotting, Northern · Cells, Cultured · Endothelium, Vascular · Female · Granulosa Cells · Human · Hydroxymethylglutaryl-CoA Reductase Inhibitors · Liver · Lovastatin · Pigment Epithelium of Eye · RNA, Messenger · Simvastatin · Sterols · Umbilical Veins
[Abstract]

3 Different effects of the hypolipidemic drugs pravastatin and lovastatin on the cholesterol biosynthesis of the human ocular lens in organ culture and on the cholesterol content of the rat lens in vivo
article 1993    
Author: Vries, A.C.J. de · Cohen, L.H.
Keywords: Health · HMG-CoA reductase inhibitor · Ocular lens · Pravastatin · Vastatin · hydroxymethylglutaryl coenzyme a reductase · mevinolin · animal experiment · cholesterol synthesis · human tissue · lens · Adult · Aged · Animal · Cholesterol · Comparative Study · Fatty Acids · Human · Lens, Crystalline · Lovastatin · Middle Age · Organ Culture · Pravastatin · Rats · Rats, Wistar · Animalia · Rattus norvegicus
[Abstract]

4 C-reactive protein: A cardiovascular risk factor report on the CRP hot-topic workshop october 1, 1997
article 1998    
Author: Maat, M.P.M. de · Haverkate, F. · Kluft, C.
Keywords: Biology · Antilipemic agent · C reactive protein · Estradiol · Estrogen receptor · Pravastatin · Acute phase response · Agina pectoris · Animal model · Atherosclerosis · Cardiovascular disease · Chlamydophila pneumoniae · Controlled study · Coronary artery disease · Disease association · Estrogen therapy · Human · Hyperlipidemia · Inflammation · Nonhuman · Rrisk factor
[Abstract]

5 Vastatins inhibit cholesterol ester accumulation in human monocyte-derived macrophages
article 1991    
Author: Kempen, H.J.M. · Vermeer, M. · Wit, E.de · Havekes, L.M.
Keywords: Biology · Acetyl low density lipoproteins · Mevastatin · Modified low density lipoproteins · Cholesterol ester · Compactin · Mevinolin · Pravastatin · Human cell · Anticholesteremic Agents · Cholesterol Esters · Esterification · Human · In Vitro · Lipoproteins, LDL · Lipoproteins, VLDL · Lovastatin · Macrophages · Monocytes · Oleic Acids · Phospholipids · Simvastatin
[Abstract]

6 Vastatins have a distinct effect on sterol synthesis and progesterone secretion in human granulosa cells in vitro
article 1996    
Author: Vliet, A.K. van · Thiel, G.C.F. van · Naaktgeboren, N. · Cohen, L.H.
Keywords: Biology · HMG-CoA reductase inhibitor · Progesterone secretion · Simvastatin · Sterol synthesis · Cholesterol · Low density lipoprotein · Methysticin · Cholesterol synthesis · Controlled study · Human cell · Cells, Cultured · Cholesterol · Culture Media · Enzyme Inhibitors · Female · Follicle Stimulating Hormone · Granulosa Cells · Humans · Hydroxymethylglutaryl-CoA Reductase Inhibitors · Lovastatin · Luteinizing Hormone · Pravastatin · Progesterone · Simvastatin
[Abstract]

7 Predicting individual responses to pravastatin using a physiologically based kinetic model for plasma cholesterol concentrations
article 2014    
Author: Pas, N.C.A. van de · Rullmann, J.A.C. · Woutersen, R.A. · Ommen, B. van · Rietjens, I.M.C.M. · Graaf, A.A. de
Keywords: Biology · Cholesterol · LDL · PBK modeling · Personalized medicine · Statin response · Virtual subjects · cholesterol · High density lipoprotein cholesterol · Low density lipoprotein cholesterol · Low density lipoprotein receptor · Pravastatin · Very low density lipoprotein cholesterol · Cholesterol blood level · Cholesterol synthesis · Drug effect · Drug mechanism · Human · Kinetics · Major clinical study · Monte Carlo method · Physiologically based kinetic · Protein expression · Biomedical Innovation · Healthy Living · Life · MSB - Microbiology and Systems Biology · ELSS - Earth, Life and Social Sciences
[Abstract]

8 Action of lovastatin, simvastatin, and pravastatin on sterol synthesis and their antiproliferative effect in cultured myoblasts from human striated muscle
article 1996    
Author: Vliet, A.K. van · Nègre-Arrariou, P. · Thiel, G.C.F. van · Bolhuis, P.A. · Cohen, L.H.
Keywords: Biology · HMG-CoA reductase inhibitors · Human myoblasts · Sterol synthesis · Adenosine triphosphate · Hydroxymethylglutaryl coenzyme a reductase inhibitor · Mevinolin · Mitochondrial enzyme · Cell culture · Cell proliferation · Cell viability · Concentration response · Controlled study · Dna synthesis · Human cell · Human tissue · Muscle biopsy · Myoblast · Myopathy · Skeletal muscle · Acetic Acid · Adenosine Triphosphate · Anticholesteremic Agents · Cell Division · Cell Survival · Cells, Cultured · DNA · Enzyme Inhibitors · Humans · Hydroxymethylglutaryl-CoA Reductase Inhibitors · Lovastatin · Mitochondria · Muscle, Skeletal · Oxidoreductases · Pravastatin · Simvastatin · Sterols
[Abstract]

9 Cholestrol content of the rat lens is lowered by administration of simvastatin, but not pravastatin
article 1993    
Author: Vries, A.C.J. de · Vermeer, M.A. · Bredman, J.J. · Bar, P.R. · Cohen, L.H.
Keywords: Pharmacology · 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors · hypocholesterolaemic drugs · antilipemic agent · drug derivative · hydroxymethylglutaryl coenzyme A reductase inhibitor · hypocholesterolemic agent · mevinolin · animal experiment · cholesterol metabolism · oral drug administration · biosynthesis · dose response · drug effect · enzymology · liver microsome · metabolism · organ culture · rat strain · time · Aging · Animal · Anticholesteremic Agents · Antilipemic Agents · Cholesterol · Dose-Response Relationship, Drug · Hydroxymethylglutaryl-CoA Reductase Inhibitors · Lens, Crystalline · Lovastatin · Microsomes, Liver · Organ Culture · Pravastatin · Rats · Rats, Wistar · Simvastatin · Time Factors
[Abstract]

10 Interaction between a genetic variant of the platelet fibrinogen receptor and fibrinogen levels in determining the risk of cardiovascular events
article 2004    
Author: Boekholdt, S.M. · Peters, R.J.G. · Maat, M.P.M. de · Zwinderman, A.H. · Wall, E.E. van der · Reitsma, P.H. · Jukema, J.W. · Kastelein, J.J.P.
Keywords: fibrinogen receptor · glycoprotein IIIa · adult · angiography · cardiovascular risk · clinical trial · controlled clinical trial · controlled study · coronary artery atherosclerosis · DNA polymorphism · genetic risk · genetic variability · genotype · heterozygote · major clinical study · multicenter study · priority journal · randomized controlled trial · risk factor · survival · thrombocyte · Coronary Arteriosclerosis · Disease-Free Survival · Fibrinogen · Genotype · Humans · Integrin beta3 · Male · Middle Aged · Platelet Aggregation · Platelet Glycoprotein GPIIb-IIIa Complex · Polymorphism, Genetic · Pravastatin · Proportional Hazards Models · Receptors, Fibrinogen · Risk Assessment
[Abstract]

11 An integrated evaluation of endothelial constitutive nitric oxide synthase polymorphisms and coronary artery disease in men
article 2004    
Author: Agema, W.R.P. · Maat, M.P.M. de · Zwinderman, A.H. · Kastelein, J.J.P. · Rabelink, T.J. · Boven, A.J. van · Feskens, E.J.M. · Boer, J.M.A. · Wall, E.E. van der · Jukema, J.W.
Keywords: Biology · Biomedical Research · Atherosclerosis · Coronary artery disease · Endothelial constitutive nitric oxide synthase (ecNOS) · Genetic polymorphism · Endothelial nitric oxide synthase · Angiography · Cigarette smoking · Clinical trial · Controlled clinical trial · Controlled study · Disease course · Disease severity · DNA polymorphism · Enzyme polymorphism · Genetic association · Genotype · Heart infarction · Heart muscle ischemia · Major clinical study · Randomized controlled trial · ST segment · Anticholesteremic Agents · Case-Control Studies · Coronary Angiography · Coronary Disease · Disease Progression · Genetic Predisposition to Disease · Humans · Male · Middle Aged · Myocardial Infarction · Myocardial Ischemia · Nitric Oxide Synthase · Nitric Oxide Synthase Type III · Polymorphism, Genetic · Pravastatin · Statistics, Nonparametric
[Abstract]

12 Mouse models for atherosclerosis and pharmaceutical modifiers
article 2007    
Author: Zadelaar, A.S.M. · Kleemann, R. · Verschuren, L. · Vries-van der Weij, J. de · Hoorn, J. van der · Princen, H.M. · Kooistra, T.
Keywords: Biology · Biomedical Research · ACE inhibitors · AT1 receptor antagonists · Atherosclerosis · LXR · Mouse models · Pharmaceutical drugs · PPAR · Statins · atorvastatin · avasimibe · candesartan · captopril · cholesterol acyltransferase inhibitor · dipeptidyl carboxypeptidase inhibitor · hydralazine · hydroxymethylglutaryl coenzyme A reductase inhibitor · irbesartan · losartan · ly 465608 · n (2,2,2 trifluoroethyl) n [4 [2,2,2 trifluoro 1 hydroxy 1 (trifluoromethoxy)ethyl]phenyl]benzenesulfonamide · olmesartan · perindopril · peroxisome proliferator activated receptor alpha agonist · pirinixic acid · pitavastatin · pravastatin · quinapril · ramipril · rosuvastatin · simvastatin · telmisartan · temocapril · unindexed drug · valsartan · zofenopril · antihypertensive agent · antilipemic agent · apolipoprotein E · atherosclerosis · pathophysiology · sensitivity and specificity · Animals · Antihypertensive Agents · Antilipemic Agents · Apolipoproteins E · Atherosclerosis · Disease Models, Animal · Dose-Response Relationship, Drug · Drug Administration Schedule · Dyslipidemias · Humans · Hydroxymethylglutaryl-CoA Reductase Inhibitors · Hypertension · Male · Mice · Mice, Knockout · Mice, Transgenic · Sensitivity and Specificity
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 12 of 12 found. | Sort by date