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Showing 1 to 12 of 12 found. | Sort by date

1 The mechanism of N-acetylcysteine photoprotection is not related to dipyrimidine photoproducts
article 1998    
Author: Nijmeijer, B.A. · Steenvoorden, D.P.T. · Beijersbergen Van Henegouwen, G.M.J. · Roza, L. · Vink, A.A.
Keywords: Nutrition · DNA damage · Immunosuppression · Photoprotection · Acetylcysteine · Cyclobutane · Pyrimidine dimer · Urocanic acid · Animal experiment · Contact allergy · Dna damage · Mouse · Nonhuman · Priority journal · Ultraviolet b radiation · Acetylcysteine · Animals · DNA Damage · Epidermis · Glutathione · Male · Mice · Mice, Inbred BALB C · Pyrimidines · Ultraviolet Rays · Animalia
[Abstract]

2 Studies on the role of PPAR in the fibrate-modulated gene expression of apolipoprotein A-I, plasminogen activator inhibitor 1, and fibrinogen in primary hepatocyte cultures from cynomolgus monkey
article 1996    
Author: Kockx, M. · Princen, H.M.G. · Kooistra, T.
Keywords: Animals · Antilipemic Agents · Apolipoprotein A-I · Cells, Cultured · Female · Fibrinogen · Gene Expression Regulation · Macaca fascicularis · Male · Microbodies · Plasminogen Activator Inhibitor 1 · Pyrimidines · Receptors, Cytoplasmic and Nuclear · Transcription Factors · Animalia · Macaca fascicularis
[Abstract]

3 The influence of the wavelength of ultraviolet radiation on survival, mutation induction and DNA repair in irradiated Chinese hamster cells
article 1980    
Author: Zelle, B. · Reynolds, R.J. · Kottenhagen, M.J. · Schuite, A. · Lohman, P.H.M.
Keywords: Biology · DNA repair · Hamster · Mutation · Ultraviolet radiation · Animal · Cell Survival · Cells, Cultured · Comparative Study · Cricetulus · Deoxyribodipyrimidine Photo-Lyase · DNA · DNA Repair · Dose-Response Relationship, Radiation · Female · Hamsters · Mutation · Ovary · Pyrimidines · Substrate Specificity · Support, Non-U.S. Gov't · Ultraviolet Rays
[Abstract]

4 Inhibition of zaleplon metabolism by cimetidine in the human liver : in vitro studies with subcellular fractions and precision-cut liver slices
article 2002    
Author: Renwick, A.B. · Ball, S.E. · Tredger, J.M. · Price, R.J. · Walters, D.G. · Kao, J. · Scatina, J.A. · Lake, B.G.
Keywords: Nutrition · Aldehyde oxidase · Cimetidine · Cytochrome P450 3A · Reduced nicotinamide adenine dinucleotide phosphate · Zaleplon · Cell fractionation · Drug inhibition · Drug metabolism · Human · Human cell · Human tissue · In vitro study · Liver metabolism · Liver microsome · Liver slice · Acetamides · Cimetidine · Cytosol · Dose-Response Relationship, Drug · Drug Interactions · Enzyme Inhibitors · Humans · Hypnotics and Sedatives · Inhibitory Concentration 50 · Kinetics · Liver · Models, Chemical · Pyrimidines · Subcellular Fractions · Staphylococcus phage 3A
[Abstract]

5 Fibrate-modulated expression of fibrinogen, plasminogen activator inhibitor-1 and apolipoprotein A-I in cultured cynomolgus monkey hepatocytes. Role of the peroxisome proliferator-activated receptor-α
article 1998    
Author: Kockx, M. · Princen, H.M.G. · Kooistra, T.
Keywords: Health · Animals · Antilipemic Agents · Apolipoprotein A-I · Cells, Cultured · Clofibrate · Clofibric Acid · Dimerization · Female · Fibrinogen · Gemfibrozil · Gene Expression Regulation · Genes, Reporter · Liver · Macaca fascicularis · Male · Peroxisome Proliferators · Plasminogen Activator Inhibitor 1 · Procetofen · Pyrimidines · Receptors, Cytoplasmic and Nuclear · Receptors, Retinoic Acid · Retinoid X Receptors · Trans-Activation (Genetics) · Transcription Factors · Tretinoin
[Abstract]

6 Negative Regulation of Human Fibrinogen Gene Expression by Peroxisome Proliferator-activated Receptor α Agonists via Inhibition of CCAAT Box/Enhancer-binding Protein β
article 2001    
Author: Gervois, P. · Vu-Dac, N. · Kleemann, R. · Kockx, M. · Dubois, G. · Laine, B. · Kosykh, V. · Fruchart, J.C. · Kooistra, T. · Staels, B.
Keywords: Western blotting · Blotting, Northern · Blotting, Western · CCAAT-Enhancer-Binding Protein-alpha · Cell Line · Dose-Response Relationship, Drug · Down-Regulation · Fibrinogen · Hepatocytes · Humans · Inflammation · Interleukin-6 · Liver · Mutagenesis, Site-Directed · Nuclear Receptor Coactivator 2 · Peroxisome Proliferators · Plasmids · Precipitin Tests · Promoter Regions (Genetics) · Pyrimidines · Receptors, Cytoplasmic and Nuclear · Transcription Factors · Transcription, Genetic · Transfection · Tumor Cells, Cultured
[PDF] [Abstract]

7 Fibrates suppress bile acid synthesis via peroxisome proliferator-activated receptor-α-mediated downregulation of cholesterol 7α-hydroxylase and sterol 27-hydroxylase expression
article 2001    
Author: Post, S.M. · Duez, H. · Gervois, P.P. · Staels, B. · Kuipers, F. · Princen, H.M.G.
Keywords: Animals · Antilipemic Agents · Bile Acids and Salts · Cells, Cultured · Cholesterol · Cholesterol 7-alpha-Hydroxylase · Clofibric Acid · Cytochrome P-450 CYP27A1 · Cytochrome P-450 Enzyme System · Down-Regulation · Hepatocytes · Mice · Mice, Knockout · Pyrimidines · Rats · Receptors, Cytoplasmic and Nuclear · RNA, Messenger · Steroid Hydroxylases · Transcription Factors · Transcription, Genetic
[Abstract]

8 Isolation and molecular characterisation of the gene encoding eburicol 14α-demethylase (CYP51) from Penicillium italicum
article 1996    
Author: Nistelrooy, J.G.M. van · Brink, J.M. van den · Kan, J.A.L. van · Gorcom, R.F.M. van · Waard, M.A. de
Keywords: Biology · 14α-demethylase · Cytochrome P450 · Fungicides · Penicillium italicum · Sterol biosynthesis inhibitors · Cytochrome p450 isoenzyme · Enilconazole · Etaconazole · Fenarimol · Fungicide · Unclassified drug · Article · Controlled study · Gene isolation · Genetic analysis · Molecular cloning · Molecular genetics · Nonhuman · Penicillium · Priority journal · Sterol synthesis · Yeast · Amino Acid Sequence · Base Sequence · Blotting, Northern · Cloning, Molecular · Cytochrome P-450 Enzyme System · DNA Primers · Fungal Proteins · Fungicides, Industrial · Genes, Fungal · Lanosterol · Molecular Sequence Data · Oxidoreductases · Penicillium · Pyrimidines · Restriction Mapping · Sequence Analysis, DNA · Sequence Homology, Amino Acid
[Abstract]

9 Lipidomic approach to evaluate rosuvastatin and atorvastatin at various dosages: Investigating differential effects among statins
article 2008    
Author: Bergheanu, S.C. · Reijmers, T. · Zwinderman, A.H. · Bobeldijk, I. · Ramaker, R. · Liem, A.-H. · Greef, J. van der · Hankemeier, T. · Jukema, J.W.
Keywords: Biology · Atorvastatin · Cardiovascular risk · Phosphatidylcholines · Rosuvastatin · Sphingomyelins · Atorvastatin · Cholesterol · High density lipoprotein cholesterol · Hydroxymethylglutaryl coenzyme A reductase inhibitor · Low density lipoprotein cholesterol · Phosphatidylcholine · Rosuvastatin · Sphingomyelin · Triacylglycerol · Adult · Aged · Article · Cardiovascular risk · Cholesterol blood level · Clinical trial · Controlled clinical trial · Controlled study · Coronary artery disease · Drug dose increase · Drug efficacy · Drug megadose · Female · Human · Lipid blood level · Lipid metabolism · Lipidomics · Liquid chromatography · Low drug dose · Major clinical study · Male · Mass spectrometry · Multicenter study · Phase 3 clinical trial · Randomized controlled trial · Therapy effect · Treatment outcome · Chromatography, Liquid · Dose-Response Relationship, Drug · Fluorobenzenes · Heptanoic Acids · Humans · Hydroxymethylglutaryl-CoA Reductase Inhibitors · Lipids · Mass Spectrometry · Prospective Studies · Pyrimidines · Pyrroles · Sulfonamides
[Abstract]

10 Species differences in hepatic peroxisome proliferation, cell replication and transforming growth factor-β1 gene expression in the rat, Syrian hamster and guinea pig
article 2000    
Author: Lake, B.G. · Rumsby, P.C. · Price, R.J. · Cunninghame, M.E.
Keywords: Hepatic peroxisome proliferation · Replicative DNA synthesis · Species differences · Syrian hamster · Transforming growth factor-β1 · ciprofibrate · messenger RNA · methylclofenapate · peroxisome proliferator · peroxisome proliferator activated receptor · pirinixic acid · somatomedin B receptor · transforming growth factor beta1 · animal model · animal tissue · cell division · controlled study · DNA synthesis · enzyme activity · fatty acid oxidation · liver weight · nonhuman · species difference · Syrian hamster · Animals · Cell Division · Clofenapate · Clofibric Acid · Cricetinae · DNA · Gene Expression · Guinea Pigs · Liver · Male · Mesocricetus · Molecular Structure · Organ Size · Peroxisome Proliferators · Pyrimidines · Rats · Rats, Sprague-Dawley · Receptor, IGF Type 2 · Species Specificity · Transforming Growth Factor beta · Cavia · Cavia porcellus · Cricetinae · Mesocricetus auratus · Rodentia · Sus scrofa · Zea mays
[Abstract]

11 Use of physicochemical calculation of pKa and CLogP to predict phospholipidosis-inducing potential: A case study with structurally related piperazines
article 2004    
Author: Ploemen, J.P.H.T.M. · Kelder, J. · Hafmans, T. · Sandt, H. van de · Burgsteden, J.A. van · Salemink, P.J.M. · Esch, E. van
Keywords: Health Physiology · Physiological Sciences · Alveolar histiocystosis · Electron microscopy · Foamy macrophages · Gepirone · Lung · Phospholipidosis · Physicochemical calculated parameters · Piperazines · Sprague-Dawley rats · gepirone · piperazine · animal experiment · animal model · article · cell proliferation · cell type · controlled study · electron microscopy · histiocytosis · lipidosis · lung alveolus epithelium · lung alveolus macrophage · lymphoid tissue · macrophage activation · male · nonhuman · partition coefficient · pKa · prediction · rat · Administration, Oral · Animals · Antidepressive Agents · Chemistry, Physical · Diet · Dose-Response Relationship, Drug · Female · Foam Cells · Humans · Lipidoses · Male · Phospholipids · Pulmonary Alveoli · Pyrimidines · Rats · Rats, Sprague-Dawley · Toxicity Tests · U937 Cells · Animalia
[Abstract]

12 Rosuvastatin reduces atherosclerosis development beyond and independent of its plasma cholesterol-lowering effect in APOE*3-Leiden transgenic mice: Evidence for antiinflammatory effects of rosuvastatin
article 2003    
Author: Kleemann, R. · Princen, H.M.G. · Emeis, J.J. · Jukema, J.W. · Fontijn, R.D. · Horrevoets, A.J.G. · Kooistra, T. · Havekes, L.M.
Keywords: Biology · Biomedical Research · Cell adhesion molecules · Inhibitors · Amyloid A protein · Cell adhesion molecule · Fibrinogen · Monocyte chemotactic protein 1 · Rosuvastatin · Statine derivative · Tumor necrosis factor alpha · Antiinflammatory agent · Apolipoprotein E · Apolipoprotein E3 (Leidein) · Cytokine · Fluorobenzene · Hydroxymethylglutaryl coenzyme A reductase inhibitor · Lipid · Lipoprotein · Pyrimidine derivative · Sulfonamide · Animal cell · Animal experiment · Animal model · Animal tissue · Aorta root · Cell adhesion · Cholesterol blood level · Cholesterol diet · Controlled study · Inflammation · Monocyte · Mouse · Nonhuman · Nucleotide sequence · Transgenic mouse · Blood · Drug effect · Genetics · Immunology · Metabolism · Pathology · Animals · Anti-Inflammatory Agents · Aorta · Apolipoprotein E3 · Apolipoproteins E · Arteriosclerosis · Cell Adhesion · Cholesterol · Cytokines · Female · Fluorobenzenes · Hydroxymethylglutaryl-CoA Reductase Inhibitors · Lipids · Lipoproteins · Macrophages · Mice · Mice, Transgenic · Monocytes · Pyrimidines · Sulfonamides
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 12 of 12 found. | Sort by date