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1 Retinoid (vitamin A) metabolism : a review
article 1996    
Author: Hendriks, H.F.J.
Keywords: Nutrition · Carboxylic Ester Hydrolases · Humans · Intestines · Liver · Receptors, Cell Surface · Receptors, Retinoic Acid · Retinoids · Tretinoin · Vitamin A · Metabolism · Overview · Proteins
[Abstract]

2 Rapid metabolism of retinoic acid by cultured human vascular endothelial cells as compared to the human hepatoma cell line HepG2
article 1996    
Author: Lansink, M. · Blaner, W.S. · Kooistra, T.
Keywords: Biology · cytochrome p450 · retinoic acid · conference paper · hepatoma cell · human · human cell · metabolic rate · vascular endothelium · vitamin metabolism
[Abstract]

3 Retinoid signalling during embryogenesis
article 1996    
Author: Pijnappel, W.W.M. · Hendriks, H.F.J. · Durston, A.J.
Keywords: Central nervous system · Embryogenesis · Nuclear receptors · Retinoids · Vitamin A · cell nucleus receptor · retinoic acid · retinoic acid receptor · retinoid · retinoid x receptor · vitamin receptor · conference paper · embryo development · human · signal transduction · Animals · Cell Nucleus · Central Nervous System · Embryonic and Fetal Development · Extremities · Humans · Receptors, Retinoic Acid · Retinoids · Signal Transduction
[Abstract]

4 Inhibition of apolipoprotein(a) synthesis in cynomolgus monkey hepatocytes by retinoids via involvement of the retinoic acid receptor
article 1999    
Author: Neele, D.M. · Wit, E.C.M. de · Princen, H.M.G.
Keywords: Biology · Apolipoprotein(a) · Cynomolgus monkey hepatocytes · RAR · Retinoids · RXR · alitretinoin · apolipoprotein A · isotretinoin · retinoic acid · retinoic acid receptor · retinoid · retinoid X receptor · retinol · animal cell · article · concentration response · controlled study · dose time effect relation · drug effect · enzyme linked immunosorbent assay · gene expression · lipoprotein synthesis · liver cell · monkey · nonhuman · priority journal · Animals · Antineoplastic Agents · Apolipoproteins A · Benzoates · Dose-Response Relationship, Drug · Ligands · Lipoproteins · Liver · Macaca fascicularis · Receptors, Retinoic Acid · Retinoid X Receptors · Retinoids · RNA, Messenger · Tetrahydronaphthalenes · Time Factors · Transcription Factors
[Abstract]

5 Retinoid metabolism and all-trans retinoic acid-induced growth inhibition in head and neck squamous cell carcinoma cell lines
article 1997    
Author: Braakhuis, B.J.M. · Klaassen, I. · Leede, B.M. van der · Cloos, J. · Brakenhoff, R.H. · Copper, M.P. · Teerlink, T. · Hendriks, H.F.J. · Saag, P.T. van der · Snow, G.B.
Keywords: CRABP-II · Head and neck cancer · Metabolism · Squamous · alitretinoin · isotretinoin · messenger RNA · retinoic acid · retinoic acid binding protein · cancer cell culture · cancer inhibition · cell metabolism · controlled study · drug blood level · drug metabolism · head cancer · homeostasis · human cell · neck cancer · squamous cell carcinoma · Antineoplastic Agents · Carcinoma, Squamous Cell · Cell Division · Chromatography, High Pressure Liquid · Culture Media · Head and Neck Neoplasms · Humans · Receptors, Retinoic Acid · Retinoids · Tretinoin · Tumor Cells, Cultured
[PDF] [Abstract]

6 Acute release of tissue-type plasminogen activator (t-PA) from the endothelium ; regulatory mechanisms and therapeutic target
article 1994    
Author: Schrauwen, Y. · Vries, R.E.M. de · Kooistra, T. · Emeis, J.J.
Keywords: Biology · endothelium · fibrinolysis · regulated secretion · tissue-type plasminogen activator (t-PA) · bradykinin · butyric acid · cholera toxin · retinoic acid · thrombin · tissue plasminogen activator · animal cell · animal experiment · conference paper · endothelium cell · fibrinolysis · protein secretion · rat
[Abstract]

7 Synthesis, storage and regulated secretion of tissue-type plasminogen activator by cultured rat heart endothelial cells
article 1998    
Author: Emeis, J.J. · Hoogen, C.M. van den · Diglio, C.A.
Keywords: Health · 8 bromo cyclic amp · calcimycin · cholera toxin · forskolin · phorbol 13 acetate 12 myristate · plasminogen activator inhibitor · retinoic acid · thrombin · tissue plasminogen activator · urokinase · animal cell · article · controlled study · heart · nonhuman · priority journal · protein secretion · protein synthesis · rat · vascular endothelium
[Abstract]

8 Mechanism of the slow induction of apolipoprotein A-I synthesis by retinoids in cynomolgus hepatocytes: Involvement of retinoic acid and retinoid X receptors
article 1997    
Author: Kaptein, A. · Neele, D.M. · Twisk, J. · Hendriks, H.F.J. · Kooistra, T. · Princen, H.M.G.
Keywords: Apolipoprotein A-I · Cynomolgus hepatocytes · MRNA · RAP · Receptor-selective ligands · Retinoids · RXR · Transcriptional regulation · apolipoprotein a1 · retinoic acid · retinoid x receptor · animal cell · article · lipogenesis · lipoprotein metabolism · liver cell · liver metabolism · monkey · nonhuman · transcription regulation · Animals · Apolipoprotein A-I · Benzoates · Blotting, Northern · Cells, Cultured · Female · Gene Expression Regulation · Liver · Macaca fascicularis · Male · Receptors, Retinoic Acid · Retinoid X Receptors · Retinoids · RNA, Messenger · Tetrahydronaphthalenes · Time Factors · Trans-Activation (Genetics) · Transcription Factors · Tretinoin
[PDF] [Abstract]

9 Prediction of in vivo developmental toxicity of all-trans-retinoic acid based on in vitro toxicity data and in silico physiologically based kinetic modeling
article 2015    
Author: Louisse, J. · Bosgra, S. · Blaauboer, B.J. · Rietjens, I.M.C.M. · Verwei, M.
Keywords: Toxicology · All-trans-retinoic acid · Developmental toxicity · In vitro–in vivo extrapolation · Physiologically based kinetic modeling · Reverse dosimetry · Solid phase microextraction · Animalia · Rattus · Biomedical Innovation · Healthy Living · Life Triskelion BV · RAPID - Risk Analysis for Products in Development ARF - Analytical Research (Food) · ELSS - Earth, Life and Social Sciences
[Abstract]

10 Effect of steroid hormones and retinoids on the formation of capillary-like tubular structures of human microvascular endothelial cells in fibrin matrices is related to urokinase expression
article 1998    
Author: Lansink, M. · Koolwijk, P. · Hinsbergh, V. van · Kooistra, T.
Keywords: Health · Aprotinin · Calcitriol · Capillaries · Cell Culture Techniques · Cells, Cultured · Drug Interactions · Endothelium, Vascular · Extracellular Matrix · Fibrin · Fibroblast Growth Factor 2 · Gene Expression Regulation · Gonadal Steroid Hormones · Humans · Male · Morphogenesis · Neovascularization, Physiologic · Plasmin · Polymerase Chain Reaction · Receptors, Cell Surface · Receptors, Retinoic Acid · Receptors, Steroid · Retinoids · RNA, Messenger · Steroids · Tissue Plasminogen Activator · Triiodothyronine · Tumor Necrosis Factor-alpha · Urinary Plasminogen Activator
[Abstract]

11 Development of an androgen reporter gene assay (AR-LUX) utilizing a human cell line with an endogenously regulated androgen receptor
article 2001    
Author: Blankvoort, B.M.G. · Groene, E.M. de · Meeteren-Kreikamp, A.P. van · Witkamp, R.F. · Rodenburg, R.J.T. · Aarts, J.M.M.J.G.
Keywords: Nutrition · Aldosterone · Androgen · Androgen receptor · Androstanolone · Bolasterone · Dexamethasone · Epigallocatechin gallate · Estradiol · Forskolin · Luciferase · Progesterone · Retinoic acid · Trenbolone · Vitamin D · Assay · Cancer cell culture · Controlled study · Genetic transcription · Genetic transfection · Human · Human cell · Priority journal · Reliability · Reporter gene · Transcription regulation · Validation process · Aldosterone · Androgens · Breast Neoplasms · Dexamethasone · Down-Regulation · Estradiol · Genes, Regulator · Genes, Reporter · Humans · Luciferases · Metribolone · Receptors, Androgen · Transfection · Tumor Cells, Cultured
[Abstract]

12 Stimulators of tissue-type plasminogen activator
article 1996    
Author: Kooistra, T. · Lansink, M. · Emeis, J.J.
Keywords: Health · 4 [2 (5,6,7,8 tetrahydro 5,5,8,8 tetramethyl 2 naphthyl) 1 propenyl]benzoic acid · Benzodiazepine derivative · Butyric acid · Cyclic amp · Protein kinase c · Retinoic acid · Retinoid · Tissue plasminogen activator · Trichostatin a · U 34599 · U 46195 · U 51477 · Unclassified drug · Endothelium cell · Fibrinolysis · Human · Nonhuman · Review
[Abstract]

13 Fibrate-modulated expression of fibrinogen, plasminogen activator inhibitor-1 and apolipoprotein A-I in cultured cynomolgus monkey hepatocytes. Role of the peroxisome proliferator-activated receptor-α
article 1998    
Author: Kockx, M. · Princen, H.M.G. · Kooistra, T.
Keywords: Health · Animals · Antilipemic Agents · Apolipoprotein A-I · Cells, Cultured · Clofibrate · Clofibric Acid · Dimerization · Female · Fibrinogen · Gemfibrozil · Gene Expression Regulation · Genes, Reporter · Liver · Macaca fascicularis · Male · Peroxisome Proliferators · Plasminogen Activator Inhibitor 1 · Procetofen · Pyrimidines · Receptors, Cytoplasmic and Nuclear · Receptors, Retinoic Acid · Retinoid X Receptors · Trans-Activation (Genetics) · Transcription Factors · Tretinoin
[Abstract]

14 Stimulation of tissue-type plasminogen activator expression by retinoic acid in human endothelial cells requires retinoic acid receptor β2 induction
article 1996    
Author: Lansink, M. · Kooistra, T.
Keywords: Biology · Antisense oligodeoxynucleotide · Cycloheximide · Tetinoic acid receptor · Alternative rna splicing · Antibody response · Cell stimulation · competitive inhibition · Endothelium cell · Enzyme active site · Fibrinolysis · Gene induction · Human cell · Protein degradation · Base Sequence · Benzoates · Cells, Cultured · Chromans · Cycloheximide · DNA, Complementary · Endothelium, Vascular · Gene Expression Regulation · Humans · Molecular Sequence Data · Oligonucleotides, Antisense · Protein Synthesis Inhibitors · Receptors, Retinoic Acid · Tissue Plasminogen Activator · Tretinoin · Umbilical Veins
[Abstract]

15 Prediction of in vivo developmental toxicity of all‑trans‑retinoic acid based on in vitro toxicity data and in silico physiologically based kinetic modeling
article 2014    
Author: Louisse, J. · Bosgra, S. · Blaauboer, B.J. · Rietjens, Y.M.C.M. · Verwei, M.
Keywords: Toxicology · All-trans-retinoic acid · Developmental toxicity · In vitro-in vivo extrapolation · Physiologically based kinetic modeling · Reverse dosimetry · Solid phase microextraction · Food and Nutrition · Healthy Living · Life Triskelion BV · RAPID - Risk Assessment Products in Developmentv ARF - Analytical Research (Food) · ELSS - Earth, Life and Social Sciences TNO Bedrijven

16 Stimulation of lipogenesis by pharmacological activation of the liver X receptor leads to production of large, triglyceride-rich very low density lipoprotein particles
article 2002    
Author: Grefhorst, A. · Elzinga, B.M. · Voshol, P.J. · Plösch, T. · Kok, T. · Bloks, V.W. · Sluijs, F.H. van der · Havekes, L.M. · Romijn, J.A. · Verkade, H.J. · Kuipers, F.
Keywords: Animals · Anticholesteremic Agents · Apolipoproteins E · Carrier Proteins · Cell Line · DNA-Binding Proteins · Hypertriglyceridemia · Lipids · Lipoproteins, VLDL · Liver · Male · Membrane Proteins · Mice · Mice, Inbred C57BL · Phospholipid Transfer Proteins · Rats · Receptors, Cytoplasmic and Nuclear · Receptors, LDL · Receptors, Retinoic Acid · Receptors, Thyroid Hormone · Sulfonamides · Triglycerides · Animalia · Mus musculus
[PDF] [Abstract]

17 Effect of retinol and cigarette-smoke and condensate on dye-coupled intercellular communication between hamster tracheal epithelial cells
article 1988    
Author: Rutten, A.A.J.J.L. · Jongen, W.M.F. · Haan, L.H.J.de · Hendriksen, E.G.J. · Koeman, J.H.
Keywords: cigarette smoke · lucifer yellow · radioisotope · retinoic acid · retinol · animal cell cell junction · cytochemistry · cytology · female · male · nonhuman · trachea · ultrastructure · Animal · Cell Communication · Cells, Cultured · Dimethyl Sulfoxide · Epithelial Cells · Epithelium · Fluorescent Dyes · Hamsters · Isoquinolines · Mesocricetus · Mucociliary Clearance · Plants, Toxic · Smoke · Support, Non-U.S. Gov't · Tobacco · Trachea · Vitamin A
[Abstract]

18 Influence of retinoids on the mutagenicity of cigarette-smoke condensate in Salmonella typhimurium TA98
article 1986    
Author: Wilmer, J.W.G.M. · Spit, B.J.
Keywords: Cigarette smoke condensate · Retinoic acid · Retinol · Retinol acetate · Tobacco · Ames test · Chemical mutagenesis · Heredity · In vitro study · Mutagenicity · Nonhuman · Priority journal · Salmonella typhimurium · Comparative Study · Mutagenicity Tests · Mutagens · Mutation · Retinoids · Salmonella typhimurium · Smoke · Smoking · Structure-Activity Relationship · Support, Non-U.S. Gov't
[Abstract]

19 Differences in metabolism and isomerization of all-trans-retinoic acid and 9-cis-retinoic acid between human endothelial cells and hepatocytes
article 1997    
Author: Lansink, M. · Bennekum, A.M. van · Blaner, W.S. · Kooistra, T.
Keywords: Health · Human endothelial cell · Human hepatocyte · Isomerization · Metabolism · Liarozole · Plasminogen activator · Retinoic acid · Cell culture · Controlled study · Drug metabolism · Endothelium cell · High performance liquid chromatography · Human cell · In vitro study · Isomerism · Isotope labeling · Liver cell culture · Lliver metabolism · Biotransformation · Cells, Cultured · Chromatography, High Pressure Liquid · Endothelium, Vascular · Humans · Isomerism · Kinetics · Liver · Tretinoin · Umbilical Veins
[Abstract]

20 Retinoids increase human apo C-III expression at the transcriptional level via the retinoid X receptor : Contribution to the hypertriglyceridemic action of retinoids
article 1998    
Author: Vu-Dac, N. · Gervois, P. · Torra, I.P. · Fruchart, J.C. · Kosykh, V. · Kooistra, T. · Princen, H.M.G. · Dallongeville, J. · Staels, B.
Keywords: Health · Gene regulation · Hyperlipidemia · Nuclear receptors · Retinoids · Triglycerides · Adult · Apolipoprotein C-III · Apolipoproteins C · Benzoates · Carcinoma, Hepatocellular · Cells, Cultured · Dimerization · Double-Blind Method · Gene Expression Regulation · Hela Cells · Humans · Hypertriglyceridemia · Isotretinoin · Liver · Liver Neoplasms · Male · Mutagenesis, Site-Directed · Promoter Regions (Genetics) · Receptors, Cytoplasmic and Nuclear · Receptors, Retinoic Acid · Recombinant Fusion Proteins · Regulatory Sequences, Nucleic Acid · Retinoid X Receptors · Retinoids · Tetrahydronaphthalenes · Transcription Factors · Transcription, Genetic · Transfection · Tumor Cells, Cultured
[PDF] [Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 28 found. Next | Sort by date