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1 Atherosclerosis and liver inflammation induced by increased dietary cholesterol intake: A combined transcriptomics and metabolomics analysis
article 2007    
Author: Kleemann, R. · Verschuren, L. · Erk, M.J. van · Nikolsky, Y. · Cnubben, N.H.P. · Verheij, E.R. · Smilde, A.K. · Hendriks, H.F.J. · Zadelaar, A.S.M. · Smith, G.J. · Kaznacheev, V. · Nikolskaya, T. · Melnikov, A. · Hurt-Camejo, E. · Greef, J. van der · Ommen, B. van · Kooistra, T.
Keywords: Analytical research · Biomedical research · alanine aminotransferase · aspartate aminotransferase · cholesterol · endothelial leukocyte adhesion molecule 1 · gamma interferon · high density lipoprotein · hydroxymethylglutaryl coenzyme A reductase · immunoglobulin enhancer binding protein · interleukin 1 · low density lipoprotein · peroxisome proliferator activated receptor alpha · platelet derived growth factor · protein p53 · retinoid X receptor · retinoid X receptor alpha · serum amyloid A · Smad3 protein · STAT1 protein · STAT3 protein · STAT5 protein · sterol regulatory element binding protein 1 · sterol regulatory element binding protein 2 · transcription factor FKHR · transcription factor Sp1 · transcription factor YY1 · triacylglycerol · tumor necrosis factor alpha · very low density lipoprotein · alanine aminotransferase blood level · animal experiment · animal model · animal tissue · article · aspartate aminotransferase blood level · atherosclerosis · cholesterol blood level · cholesterol diet · cholesterol intake · controlled study · diet supplementation · female · gene control · genetic transcription · hepatitis · hypercholesterolemia · lipid metabolism · metabolomics · mouse · nonhuman · pathophysiology · protein blood level · stress · transcription regulation · transcriptomics · triacylglycerol blood level · upregulation · animal · biological model · diet · disease model · gene expression regulation · inflammation · liver · metabolism · pathology · systems biology · Mus · Animals · Atherosclerosis · Cholesterol, Dietary · Diet · Disease Models, Animal · Female · Gene Expression Regulation · Inflammation · Lipid Metabolism · Liver · Metabolism · Mice · Models, Biological · Systems Biology · Transcription, Genetic
[Abstract]

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