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Showing 1 to 9 of 9 found. | Sort by date

1 Proteolytic shedding of the macrophage scavenger receptor CD163 in multiple sclerosis
article 2007    
Author: Fabriek, B.O. · Møller, H.J. · Vloet, R.P.M. · Winsen, L.M. van · Hanemaaijer, R. · Teunissen, C.E. · Uitdehaag, B.M.J. · Berg, T.K. van den · Dijkstra, C.D.
Keywords: Health · Biomedical Research · CD163 · Metalloproteinase · Monocytes · Multiple sclerosis · Scavenger receptor · sCD163 · CD163 antigen · cytokine · gelatinase B · scavenger receptor · adult · aged · analytic method · article · comparative study · controlled study · cytokine production · down regulation · enzyme activity · female · human · major clinical study · male · multiple sclerosis · priority journal · protein degradation · upregulation · Adolescent · Adult · Aged · Aged, 80 and over · Animals · Antigens, CD · Antigens, Differentiation, Myelomonocytic · Cell Line, Transformed · Cricetinae · Cricetulus · Cytokines · Enzyme Inhibitors · Enzyme-Linked Immunosorbent Assay · Female · Humans · Hydrocortisone · Male · Matrix Metalloproteinase 2 · Matrix Metalloproteinase 9 · Middle Aged · Multiple Sclerosis · Receptors, Cell Surface · Statistics, Nonparametric · Transfection
[Abstract]

2 Macrophage specific overexpression of the human macrophage scavenger receptor in transgenic mice, using a 180-kb yeast artificial chromosome, leads to enhanced foam cell formation of isolated peritoneal macrophages
article 1999    
Author: Winther, M.P.J. de · Dijk, K.W. van · Vlijmen, B.J.M. van · Gijbels, M.J.J. · Heus, J.J. · Wijers, E.R. · Bos, A.C. van den · Breuer, M. · Frants, R.R. · Havekes, L.M. · Hofker, M.H.
Keywords: Biology · Acetyl-low density lipoprotein · Macrophage scavenger receptor · Transgenics · Yeast artificial chromosome · acetyl low density lipoprotein · cholesterol ester · scavenger receptor · animal cell · animal experiment · article · atherogenesis · cell proliferation · controlled study · foam cell · gene overexpression · immunohistochemistry · mouse · nonhuman · peritoneum macrophage · priority journal · transgenic mouse · yeast artificial chromosome · Animals · Base Sequence · Cells, Cultured · Chromosomes, Artificial, Yeast · Disease Models, Animal · Foam Cells · Gene Expression · Humans · Kupffer Cells · Lipoproteins, LDL · Macrophages, Peritoneal · Mice · Mice, Transgenic · Molecular Sequence Data · Polymerase Chain Reaction · Receptors, Immunologic · Receptors, Scavenger · RNA, Messenger · Scavenger Receptors, Class A · Sensitivity and Specificity · Species Specificity · Tissue Distribution
[Abstract]

3 Scavenger Receptor BI Plays a Role in Facilitating Chylomicron Metabolism
article 2004    
Author: Out, R. · Kruijt, J.K. · Rensen, P.C.N. · Hildebrand, R.B. · Vos, P. de · Eck, M. van · Berkel, T.J.C. van
Keywords: Biology · Biomedical Research · Emulsions · Metabolism · Proteins · Cell association · High density lipoproteins (HDL) · Biochemistry · Chylomicron · High density lipoprotein cholesterol · Low density lipoprotein receptor · Low density lipoprotein receptor related protein · Oxidized low density lipoprotein · Scavenger receptor · Scavenger receptor BI · Triacylglycerol · Unclassified drug · Animal cell · Animal experiment · Cholesterol transport · Controlled study · Emulsion · Internalization · Lipid metabolism · Liver cell · Molecular recognition · Mouse · Nonhuman · Postprandial state · Animals · Antigens, CD36 · Binding Sites · Biological Transport · Chylomicron Remnants · Chylomicrons · Emulsions · Hepatocytes · Mice · Mice, Mutant Strains · Receptors, Immunologic · Receptors, Scavenger · Scavenger Receptors, Class B · Tissue Distribution · Triglycerides · Animalia
[PDF] [Abstract]

4 Characterization of atherosclerotic lesions in apo E3-leiden transgenic mice
article 1998    
Author: Leppänen, P. · Luoma, J.S. · Hofker, M.H. · Havekes, L.M. · Ylä-Herttuala, S.
Keywords: Health · Apo E · Familial dyslipoproteinemia · LRP · Oxidized LDL · Scavenger receptor · Animals · Aorta · Apolipoprotein E3 · Apolipoproteins E · Arteriosclerosis · Cholesterol · Electrophoresis, Agar Gel · Foam Cells · Humans · LDL-Receptor Related Protein 1 · Lipoproteins, LDL · Mice · Mice, Inbred C57BL · Mice, Transgenic · Receptors, Immunologic · Receptors, LDL
[Abstract]

5 Apolipoprotein CI inhibits scavenger receptor BI and increases plasma HDL levels in vivo
article 2008    
Author: Haan, W. de · Out, R. · Berbée, J.F.P. · Hoogt, C.C. van der · Dijk, K.W.v. · Berkel, T.J.C. van · Romijn, J.A. · Wouter Jukema, J. · Havekes, L.M. · Rensen, P.C.N.
Keywords: Health · Physiological Sciences · High density lipoprotein · Oxidized LDL · SR-BI · Transgenic mice · cholesterol ester · high density lipoprotein cholesterol · scavenger receptor BI · Adenovirus · animal cell · cholesterol metabolism · dose response · in vivo study · liver cell · mouse · nonhuman · particle size · protein expression · Adenoviridae · Animals · Apolipoprotein C-I · Cholesterol, HDL · Gene Transfer Techniques · Hepatocytes · Humans · Mice · Mice, Knockout · Scavenger Receptors, Class B · Adenoviridae · Murinae · Mus · Mus musculus
[Abstract]

6 The hepatic uptake of VLDL in lrp-ldlr-/-vldlr-/- mice is regulated by LPL activity and involves proteoglycans and SR-BI
article 2008    
Author: Hu, L. · Hoogt, C.C. van der · Espirito Santo, S.M.S. · Out, R. · Kypreos, K.E. · Vlijmen, B.J.M. van · Berkel, T.J.C. van · Romijn, J.A. · Havekes, L.M. · Dijk, K.W. van · Rensen, P.C.N.
Keywords: Biology · Apolipoprotein · Denovirus-mediated gene transfer · Lipoprotein lipase · Low density lipoprotein receptor · Low density lipoprotein receptor-related protein · Transgenic mice · Triglyceride-rich emulsion particles · Very low density lipoprotein receptor · apolipoprotein E · cell surface protein · cholesterol · lipoprotein lipase · low density lipoprotein receptor · low density lipoprotein receptor related protein · proteoglycan · proteoheparan sulfate · scavenger receptor BI · triacylglycerol · very low density lipoprotein · very low density lipoprotein receptor · CD36 antigen · ligand · very low density lipoprotein cholesterol · Adenovirus · animal cell · animal experiment · animal tissue · article · cell isolation · cell surface · controlled study · enzyme activity · in vitro study · in vivo study · internalization · lipid analysis · liver cell · male · mouse · nonhuman · priority journal · protein expression · regulatory mechanism · animal · blood · emulsion · genetics · liver · metabolism · mouse mutant · Animals · Antigens, CD36 · Cholesterol, VLDL · Emulsions · LDL-Receptor Related Proteins · Ligands · Lipoprotein Lipase · Liver · Male · Mice · Mice, Knockout · Proteoglycans · Receptors, LDL · Healthy for Life · Healthy Living
[Abstract]

7 DMBT1 functions as pattern-recognition molecule for poly-sulfated and poly-phosphorylated ligands
article 2009    
Author: End, C. · Bikker, F.J. · Renner, M. · Bergmann, G. · Lyer, S. · Blaich, S. · Hudler, M. · Helmke, B. · Gassler, N. · Autschbach, F. · Ligtenberg, A.J.M. · Benner, A. · Holmskov, U. · Schirmacher, P. · Nieuw Amerongen, A.V. · Rosenstiel, P. · Sina, C. · Franke, A. · Hafner, M. · Kioschis, P. · Schreiber, S. · Poustka, A. · Mollenhauer, J.
Keywords: Health · Inflammatory bowel disease · Innate immunity · Mucosal immunity · Pattern recognition · Scavenger receptor cysteine-rich · Carrageenan · Deleted in malignant brain tumors 1 · Dextran sulfate · Glycoprotein · Heparan sulfate · Lipopolysaccharide · Lipoteichoic acid · Unclassified drug · Cell surface receptor · DMBT1 protein, human · Ligand · Phosphate · Animal experiment · Animal model · Antiinflammatory activity · Antimicrobial activity · Binding competition · Cell aggregation · Colitis · Controlled study · Crohn disease · Cytotoxicity · Dose response · Enzyme linked immunosorbent assay · Escherichia coli · Experimental mouse · Host pathogen interaction · Human · Human cell · In vitro study · Innate immunity · Intestine epithelium cell · Mouse · Nonhuman · Protein binding · Protein determination · Protein expression · Protein function · Protein motif · Protein phosphorylation · Salmonella minnesota · Salmonella typhimurium · Streptococcus gordonii · Sulfation · Bacterium · Cell line · Drug antagonism · Epithelium cell · Genetics · Immunology · Intestine · Metabolism · Microbiology · Bacteria · Carrageenan · Cell Line · Dextran Sulfate · Epithelial Cells · Humans · Intestines · Ligands · Phosphates · Receptors, Cell Surface
[Abstract]

8 Atorvastatin increases HDL cholesterol by reducing CETP expression in cholesterol-fed APOE*3-Leiden.CETP mice
article 2008    
Author: Haan, W. de · Hoogt, C.C. van der · Westerterp, M. · Hoekstra, M. · Dallinga-Thie, G.M. · Princen, H.M.G. · Romijn, J.A. · Jukema, J.W. · Havekes, L.M. · Rensen, P.C.N.
Keywords: Health · CETP · High-density lipoprotein · HMGCoA reductase · Statin · Transgenic mice · ABC transporter A1 · apolipoprotein A1 · apolipoprotein E3 · atorvastatin · cholesterol ester transfer protein · high density lipoprotein · high density lipoprotein cholesterol · messenger RNA · phospholipid transfer protein · scavenger receptor BI · very low density lipoprotein · very low density lipoprotein cholesterol · animal experiment · animal model · article · cholesterol blood level · cholesterol diet · controlled study · drug effect · gene expression · hypercholesterolemia · lipoprotein blood level · lipoprotein metabolism · male · mouse · nonhuman · priority journal · protein expression · transgenic mouse · Animals · Apolipoprotein E3 · Cholesterol Ester Transfer Proteins · Cholesterol, Dietary · Cholesterol, HDL · Cholesterol, VLDL · Dose-Response Relationship, Drug · Female · Gene Expression · Heptanoic Acids · Humans · Hydroxymethylglutaryl-CoA Reductase Inhibitors · Hypercholesterolemia · Liver · Male · Mice · Mice, Inbred C57BL · Mice, Transgenic · Pyrroles · RNA, Messenger
[Abstract]

9 Innovative pharmaceutical interventions in cardiovascular disease: Focusing on the contribution of non-HDL-C/LDL-C-lowering versus HDL-C-raisingA systematic review and meta-analysis of relevant preclinical studies and clinical trials
article 2015    
Author: Kühnast, S. · Fiocco, M. · Hoorn, J.W.A. van der · Princen, H.M.G. · Jukema, J.W.
Keywords: Biology · 3Leiden.CETP mice · ABCA1 degradation inhibitors · APOE · Apolipoprotein A-I inducer · Apolipoprotein A-I Milano · Apolipoprotein A-I mimetic · Atherosclerosis · Cardiovascular disease · CETP inhibition · Clinical outcome · Clinical trials · Delipidated HDL · Fibrates · Glitazones · Hamster · HDL-cholesterol · LCAT · LDL-cholesterol · Mouse · Myocardial infarction · Niacin · Non-HDL-cholesterol · PPAR agonists · Rabbit · Reconstituted HDL · SR-BI inhibitor · Agents affecting lipid metabolism · ATP binding cassette A1 degradation inhibitor · Cardiovascular agent · Cholesterol ester transfer protein · Cholesterol ester transfer protein inhibitor · Dalcetrapib · Fibric acid derivative · Glitazar derivative · Glitazone derivative · High density lipoprotein cholesterol · Liver X receptor agonist · Low density lipoprotein cholesterol · Nicotinic acid · Peptide derivative · Peroxisome proliferator activated receptor agonist · Placebo · Receptor blocking agent · Scavenger receptor BI inhibitor · Unclassified drug · Adverse outcome · Cardiovascular risk · Cholesterol blood level · Clinical trial (topic) · Disease association · Drug effect · Drug targeting · Heart infarction · Human · Meta analysis · Mortality · Nonhuman · Protein expression · Randomized controlled trial (topic) · Risk management · Risk reduction · Systematic review · Treatment response · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · ELSS - Earth, Life and Social Sciences
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 9 of 9 found. | Sort by date