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Showing 1 to 20 of 48 found. Next | Sort by date

1 Trehalose : a review of properties, history of use and human tolerance, and results of multiple safety studies
article 2002    
Author: Richards, A.B. · Krakowka, S. · Dexter, L.B. · Schmid, H. · Wolterbeek, A.P.M. · Waalkens-Berendsen, D.H. · Shigoyuki, A. · Kurimoto, M.
Keywords: Nutrition · Animals · Female · Humans · Male · Toxicity Tests · Trehalose · Animalia
[Abstract]

2 Refinement of risk assessment of dermally and intermittently exposed pesticide workers : a critique
article 2001    
Author: Hakkert, B.C.
Keywords: Workplace · Administration, Cutaneous · Administration, Oral · Animals · Guidelines · Humans · Occupational Exposure · Pesticides · Risk Assessment · Toxicity Tests
[Abstract]

3 Risk assessment of worker and residential exposure to pesticides : conclusions and recommendations
article 2001    
Author: Hemmen, J.J. van · Groeneveld, C.N. · Drooge, H. van · Haelst, A.G. van · Schipper, A.H.J. · Jagt, K.E. van der
Keywords: Workplace · Environmental Exposure · Humans · Models, Statistical · Occupational Exposure · Pesticides · Public Policy · Risk Assessment · Toxicity Tests
[Abstract]

4 Animal behavioral methods in neurotoxicity assessment : SGOMSEC joint report
article 1996    
Author: Kulig, B. · Alleva, E. · Bignami, G. · Cohn, J. · Cory-Slechta, D. · Landa, V. · O'donoghue, J. · Peakall, D.
Keywords: Toxicology · Animals · Behavior, Animal · Cognition · Drug Evaluation, Preclinical · Ethology · Motor Activity · Nervous System Diseases · Neurotoxins · Risk Assessment · Toxicity Tests
[Abstract]

5 Prediction of local irritant effects after repeated dermal and respiratory exposure to chemicals
article 2002    
Author: Rennen, M.A.J. · Nordheim, K. · Houben, G.F. · Heer, C. de
Keywords: Nutrition · Administration, Cutaneous · Animals · Databases, Factual · Disease Models, Animal · Humans · Inhalation Exposure · Irritants · Models, Theoretical · Occupational Exposure · Predictive Value of Tests · Respiratory System · Risk Assessment · Skin · Toxicity Tests
[Abstract]

6 The chicken enucleated eye test (CEET) : a practical (pre)screen for the assessment of eye irritation/corrosion potential of test materials
article 1996    
Author: Prinsen, M.K.
Keywords: Toxicology · Animal Testing Alternatives · Animals · Chickens · Cornea · Corneal Opacity · Drug Evaluation, Preclinical · Epithelium · Eye Enucleation · Irritants · Rabbits · Toxicity Tests · Animalia · Gallus gallus · Oryctolagus cuniculus
[Abstract]

7 Strategies to replace in vivo acute systemic toxicity testing: The report and recommendations of ECVAM workshop 50
article 2004    
Author: Gennari, A. · Berghe, C. van den · Casati, S. · Castell, J. · Clemedson, C. · Coecke, S. · Colombo, A. · Curren, R. · Dal Negro, G. · Goldberg, A. · Gosmore, C. · Hartung, T. · Langezaal, I. · Lessigiarska, I. · Maas, W. · Mangelsdorf, I. · Parchment, R. · Prieto, P. · Sintes, J.R. · Ryan, M. · Schmuck, G. · Stitzel, K. · Stokes, W. · Vericat, J.A. · Gribaldo, L.
Keywords: Toxicology Health · Physiological Sciences · acute toxicity · conference paper · cytotoxicity · environmental protection · European Union · in vivo study · LD 50 · priority journal · toxicity testing · Acute Toxicity Tests · Animal Testing Alternatives · Animals · Cell Death · Cosmetics · Europe · Guidelines · Lethal Dose 50 · Mouth Diseases · Registries · Reproducibility of Results · Toxicity Tests · United States

8 Toxicity to nasal-associated lymphoid tissue
article 2003    
Author: Kuper, C.F. · Arts, J.H.E. · Feron, V.J.
Keywords: Toxicology Health · Toxicology and Applied Pharmacology · Immunotoxicity · Mucosal immunity · NALT · clinical examination · conference paper · histopathology · immune system · lymphoid tissue · nonhuman · nose · practice guideline · priority journal · toxicity · Hazardous Substances · Humans · Nasal Mucosa · Toxicity Tests · Animalia
[Abstract]

9 The Draize Eye Test and in vitro alternatives; a left-handed marriage?
article 2006    
Author: Prinsen, M.K.
Keywords: Biology · Toxicology and Applied Pharmacology · Draize Eye Test · In vitro assay · Validation · article · draize eye test · exposure · in vitro study · nonhuman · solid · technique · validation process · Acute Toxicity Tests · Animal Testing Alternatives · Animals · Eye · Irritants · Rabbits · Reproducibility of Results

10 Assessment factors for human health risk assessment: A discussion paper
article 1999    
Author: Vermeire, T. · Stevenson, H. · Pieters, M.N. · Rennen, M. · Slob, W. · Hakkert, B.C.
Keywords: Nutrition · Data base · Dose response · Health hazard · Human · Motivation · Probability · Risk assessment · Standard · Animals · Benchmarking · Dose-Response Relationship, Drug · Health · Humans · No-Observed-Adverse-Effect Level · Probability · Risk Assessment · Risk Factors · Toxicity Tests
[Abstract]

11 The benchmark approach applied to a 28-day toxicity study with rhodorsil silane in rats : the impact of increasing the number of dose groups
article 2001    
Author: Woutersen, R.A. · Jonker, D. · Stevenson, H. · Biesebeek, J.D. te · Slob, W.
Keywords: Nutrition · Alanine Transaminase · Animals · Aspartate Aminotransferases · Dose-Response Relationship, Drug · Erythrocyte Count · Female · Hematopoiesis · Hemoglobins · Liver · No-Observed-Adverse-Effect Level · Organ Size · Rats · Rats, Wistar · Research Design · Silanes · Silicates · Spleen · Toxicity Tests · Animalia · Zea mays
[Abstract]

12 Release of arachidonic and linoleic acid metabolites in skin organ cultures as characteristics of in vitro skin irritancy
article 1995    
Author: Sandt, J.J.M. van de · Maas, W.J.M. · Doornink, P.C. · Rutten, A.A.J.J.L.
Keywords: Biology · Animal · Animal Testing Alternatives · Arachidonic Acid · Benzalkonium Compounds · Eicosanoids · Epidermis · Female · Formaldehyde · Human · Hydroxyeicosatetraenoic Acids · In Vitro · Irritants · Linoleic Acid · Linoleic Acids · Male · Organ Culture · Rabbits · Skin · Sodium Dodecyl Sulfate · Support, Non-U.S. Gov't · Toxicity Tests
[Abstract]

13 Toxicology of chemical mixtures : challenges for today and the future
article 1995    
Author: Feron, V.J. · Groten, J.P. · Jonker, D. · Cassee, F.R. · Bladeren, P.J. van
Keywords: Toxicology · Administration, Inhalation · Administration, Oral · Aldehydes · Animals · Drug Interactions · Hazardous Substances · Kidney Diseases · Organ Specificity · Rats · Rats, Wistar · Research Design · Risk Assessment · Toxicity Tests · Xenobiotics · Animalia · Complex mixtures · Defined · Standard setting · Study designs
[Abstract]

14 Safety evaluation of an α-cyclodextrin glycosyltranferase preparation
article 2004    
Author: Bär, A. · Krul, C.A.M. · Jonker, D. · Vogel, N. de
Keywords: Biology · Toxicology and Applied Pharmacology · alpha cyclodextrin glycosyltransferase · amylase · unclassified drug · Ames test · animal experiment · animal model · animal tissue · article · aspiration · bacterial strain · batch fermentation · chromosome aberration · controlled study · Escherichia coli · evaluation · female · food safety · foraging · gastroesophageal reflux · genetic recombination · genotoxicity · Klebsiella oxytoca · lymphocyte culture · male · nonhuman · priority journal · rat · respiratory tract disease · toxicity testing · Animals · Chromosome Aberrations · Escherichia coli · Female · Food Additives · Glucosyltransferases · Humans · Klebsiella · Lymphocytes · Male · Mutagenicity Tests · Rats · Rats, Wistar · Toxicity Tests · Toxicity Tests, Chronic · Escherichia coli · Klebsiella oxytoca
[Abstract]

15 Evaluation of potential neurotoxic effects of occupational exposure to (L)-Lactates
article 2001    
Author: Clary, J.J. · Feron, V.J. · Velthuijsen, J.A. van
Keywords: Toxicology · Chronic neurotoxicity · Chronic toxic encephalopathy · Lactate esters · Organo psycho syndrome · Solvents · 2 ethylhexanol · 2 propanol · alcohol · butanol · isobutanol · lactic acid derivative · methanol · propanol · animal experiment · article · brain disease · disease association · hydrolysis · mouse · neurotoxicity · nonhuman · occupational exposure · priority journal · rat · risk assessment · toxicity testing · Alcohols · Animals · Esters · Humans · Hydrolysis · Lactates · Neurotoxicity Syndromes · No-Observed-Adverse-Effect Level · Occupational Exposure · Solvents · Toxicity Tests · Volatilization
[Abstract]

16 Approaches to risk assessment in food allergy: Report from a workshop ''developing a framework for assessing the risk from allergenic foods"
article 2009    
Author: Madsen, C.B. · Hattersley, S. · Buck, J. · Gendel, S.M. · Houben, G.F. · Hourihane, J.OB. · Mackie, A. · Mills, E.N.C. · Nørhede, P. · Taylor, S.L. · Crevel, R.W.R.
Keywords: Chemistry Nutrition · Food and Chemical Risk Analysis · Food allergy · Margin of Exposure · Probabilistic · Risk assessment · Uncertainty factors · food allergen · allergy · article · food allergy · food intake · human · peanut allergy · probability · risk assessment · scoring system · statistical model · Animals · Disease Models, Animal · Food · Food Hypersensitivity · Food Supply · Humans · Plant Proteins · Risk Assessment · Toxicity Tests
[Abstract]

17 Inhalation toxicity studies: OECD guidelines in relation to REACH and scientific developments
article 2008    
Author: Arts, J.H.E. · Muijser, H. · Jonker, D. · Sandt, J.J.M. van de · Bos, P.M.J. · Feron, V.J.
Keywords: Health · Chemicals · Guidelines · Hazard · Inhalation · OECD · Reach · Toxicity · acute toxicity · animal testing alternative · article · health hazard · inhalation · nonhuman · practice guideline · risk assessment · safety · toxicity · Animal Testing Alternatives · Animals · European Union · Government Regulation · Guidelines as Topic · Inhalation Exposure · Risk Assessment · Tissue Culture Techniques · Toxicity Tests · Xenobiotics · Animalia
[Abstract]

18 Skin sensitisation and epidermal disposition: The relevance of epidermal disposition for sensitisation hazard identification and risk assessment: The report and recommendations of ECVAM workshop 59a
article 2007    
Author: Basketter, D. · Pease, C. · Kasting, G. · Kimber, I. · Casati, S. · Cronin, M. · Diembeck, W. · Gerberick, F. · Hadgraft, J. · Hartung, T. · Marty, J.P. · Nikolaidis, E. · Patlewicz, G. · Roberts, D. · Roggen, E. · Rovida, C. · Sandt, J. van de
Keywords: Food and Chemical Risk Analysis · cosmetic · analytic method · clearance · conference paper · environmental exposure · epidermis cell · gap junction · hazard assessment · immunity · mathematical computing · priority journal · protein binding · risk assessment · sensitization · skin sensitization · steady state · theoretical model · Allergens · Animal Testing Alternatives · Animals · Cells, Cultured · Guidelines · Humans · Risk Assessment · Skin · Skin Absorption · Skin Tests · Toxicity Tests

19 Animal models to test respiratory allergy of low molecular weight chemicals: A guidance
article 2007    
Author: Arts, J.H.E. · Kuper, C.F.
Keywords: Health · Toxicology and Applied Pharmacology · Animal model · Challenge · LMW chemical · Respiratory allergy · Sensitisation · Test method · allergen · chemical compound · allergic asthma · animal experiment · animal model · article · controlled study · dose response · maximum allowable concentration · mouse · nonhuman · priority journal · rat · respiratory tract allergy · risk assessment · sensitivity analysis · sensitization · Allergens · Animals · Asthma · Disease Models, Animal · Guidelines · Hypersensitivity · Irritants · Molecular Weight · Toxicity Tests · Animalia
[Abstract]

20 Subchronic (13-week) oral toxicity study of α-cyclodextrin in dogs
article 2004    
Author: Lina, B.A.R. · Bär, A.
Keywords: Biology Toxicology · Toxicology and Applied Pharmacology · alpha cyclodextrin · animal experiment · animal model · animal tissue · article · cecum · colon · controlled study · diarrhea · dietary intake · dog · female · food intake · histopathology · intestine · male · mortality · nonhuman · ophthalmoscopy · priority journal · statistical significance · urine · urine pH · Administration, Oral · alpha-Cyclodextrins · Animals · Cyclodextrins · Diarrhea · Dogs · Female · Male · No-Observed-Adverse-Effect Level · Organ Size · Toxicity Tests, Chronic · Canis familiaris
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 48 found. Next | Sort by date