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1 Anacetrapib reduces (V)LDL-cholesterol by inhibition of CETP activity and reduction of plasma PCSK9
article 2015    
Author: Tuin, S.J. van der · Kühnast, S. · Berbée, J. · Verschuren, L. · Pieterman, E.J. · Havekes, L.M. · Hoorn, J.W. van der · Rensen, P.C. · Jukema, J.W. · Princen, H.M. · Willems van Dijk, K. · Wang, Y.
Keywords: Health · CETP · Cholesterol · Metabolism · Drug therapy · Hypolipidemic drugs · LDL · Metabolism · Lipids · Lipoproteins · PCSK9 · Anacetrapib · Apolipoprotein B · Cholesterol ester transfer protein · Low density lipoprotein receptor · Proprotein convertase subtilisin kexin type 9 · RNA · Serine proteinase · Sterol regulatory element binding protein 1 · Sterol regulatory element binding protein 2 · Triacylglycerol · Unclassified drug · Very low density lipoprotein cholesterol · Animal experiment · Animal tissue · Atherosclerosis · Cholesterol synthesis · Controlled study · Down regulation · Drug mechanism · Enzyme blood level · Female · Liver · Microarray analysis · Mouse · Nonhuman · Polymerase chain reaction · Protein expression · RNA isolation · Western diet · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research MSB - Microbiology and Systems Biology · ELSS - Earth, Life and Social Sciences
[PDF] [Abstract]

2 Atorvastatin accelerates clearance of lipoprotein remnants generated by activated brown fat to further reduce hypercholesterolemia and atherosclerosis
article 2017    
Author: Hoeke, G. · Wang, Y. · Dam, A.D. van · Mol, M. · Gart, E. · Klop, H.G. · Berg, S.M. van den · Pieterman, E.H. · Princen, H.M.G. · Groen, A.K. · Rensen, P.C.N. · Berbée, J.F.P. · Boon, M.R.
Keywords: Biology · Atherosclerosis · Brown adipose tissue · Hypercholesterolemia · Cholesterol metabolism · Lipid and lipoprotein metabolism · 5 [2 [[2 (3 chlorophenyl) 2 hydroxyethyl]amino]propyl] 1,3 benzodioxole 2,2 dicarboxylic acid · Atorvastatin · Cholesterol · Fatty acid · High density lipoprotein cholesterol · Lipoprotein · Proprotein convertase 9 · Triacylglycerol · Animal experiment · Animal model · Animal tissue · Atherosclerosis · Brown adipose tissue · Cholesterol blood level · Controlled study · Drug effect · Drug potentiation · Energy expenditure · Female · Gene expression · Hypercholesterolemia · Lipid composition · Lipid liver level · Lipid metabolism · Lipid oxidation · Lipid transport · Lipoprotein metabolism · Mouse · Nonhuman · Triacylglycerol blood level · Western diet · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · EELS - Earth, Environmental and Life Sciences
[Abstract]

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