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Showing 1 to 15 of 15 found. | Sort by date

1 Correlation network analysis for data integration and biomarker selection
article 2008    
Author: Adourian, A. · Jennings, E. · Balasubramanian, R. · Hines, W.M. · Damian, D. · Plasterer, T.N. · Clish, C.B. · Stroobant, P. · McBurney, R. · Verheij, E.R. · Bobeldijk, I. · Greef, J. van der · Lindberg, J. · Kenne, K. · Andersson, U. · Hellmold, H. · Nilsson, K. · Salter, H. · Schuppe-Koistinen, I.
Keywords: Nutrition · Biological marker · Glycosyltransferase · Lipid · Ornithine · Animal · Article · Blood · Enzymology · Liver · Male · Metabolism · Rat · Systems biology · Wistar rat · Animals · Biological Markers · Glycosyltransferases · Lipids · Liver · Male · Ornithine · Rats · Rats, Wistar · Systems Biology · Animalia · Rattus · Rodentia
[PDF] [Abstract]

2 Allergic inflammation in the upper respiratory tract of the rat upon repeated inhalation exposure to the contact allergen dinitrochlorobenzene (DNCB).
article 2010    
Author: Triel, J.J. van · Arts, J.H. · Muijser, H. · Kuper, C.F.
Keywords: Chemistry · 1 chloro 2,4 dinitrobenzene · allergen · autacoid · animal · article · breathing mechanics · comparative study · drug effect · exposure · female · immunology · inhalational drug administration · pathology · pathophysiology · rat · respiratory system · skin allergy · Wistar rat · Administration, Inhalation · Allergens · Animals · Dermatitis, Allergic Contact · Dinitrochlorobenzene · Female · Inflammation Mediators · Inhalation Exposure · Rats · Rats, Wistar · Respiratory Mechanics · Respiratory System
[Abstract]

3 Lack of clastogenic effects in cultured human lymphocytes treated with hydroquinone
article 2003    
Author: Roza, L. · Vogel, N. de · Delft, J.H.M. van
Keywords: Biology Health · Physiological Sciences · Antimutagen · Clastogenicity · Human lymphocytes · Hydroquinone · Mutagenicity · hydrogen peroxide · hydroquinone · hydroquinone derivative · mutagenic agent · oxidizing agent · article · concentration response · controlled study · cytotoxicity · genotoxicity · human · human cell · lymphocyte culture · male · metabolic activation · mutagenicity · normal human · structural chromosome aberration · animal · biotransformation · cell culture · chromatid · chromosome aberration · drug effect · in vitro study · liver · lymphocyte · metabolism · mutagen testing · rat · Wistar rat · Animalia · Animals · Biotransformation · Cells, Cultured · Chromatids · Chromosome Aberrations · Humans · Hydrogen Peroxide · Hydroquinones · Liver · Lymphocytes · Male · Mutagenicity Tests · Mutagens · Oxidants · Rats · Rats, Wistar
[Abstract]

4 Effects of cyclosporin A and cyclophosphamide on Peyer's patches in rat, exposed in utero and neonatally or during adult age
article 2007    
Author: Kuper, C.F. · Zijverden, M. van · Klaassen, C. · Tegelenbosch-Schouten, M. · Wolterbeek, A.P.M.
Keywords: Biology · Toxicology and Applied Pharmacology · Adult exposure · Cyclophosphamide · Cyclosporin · Fetal exposure · Peyer's patches · Rat · cyclophosphamide · cyclosporin A · animal experiment · animal tissue · article · controlled study · drug effect · female · fetotoxicity · germinal center · gestation period · immunotoxicity · lactation · lymphocyte · male · microscopy · newborn period · nonhuman · Peyer patch · pregnancy · priority journal · rat · small intestine · Wistar rat · Administration, Oral · Aging · Animals · Cell Count · Cyclophosphamide · Cyclosporine · Female · Germinal Center · Immunosuppressive Agents · Injections, Intravenous · Male · Peyer's Patches · Pregnancy · Prenatal Exposure Delayed Effects · Rats · Rats, Wistar · Animalia · Rattus · Rattus norvegicus
[Abstract]

5 Histopathology of a spontaneously developing mast cell sarcoma in a Wistar rat
article 1996    
Author: Baselmans, A.H.C. · Kuijpers, M.H.M. · Dijk, J.E. van
Keywords: Toxicology · blood basophilia · eosinophilic granulocytes · eyelid · intracytoplasmatic granules · Mast cell tumor · metachromasia · animal model · animal tissue · article · basophil · cancer diagnosis · eosinophil · female · histopathology · immunohistochemistry · male · nonhuman · priority journal · rat · sarcoma · animal · animal disease · case report · eye · eyelid tumor · leukocyte count · liver tumor · lymph node metastasis · metastasis · pathology · rodent disease · ultrastructure · Wistar rat · Animalia · Exophthalmus · Rattus norvegicus · Animals · Eye · Eyelid Neoplasms · Female · Leukocyte Count · Liver Neoplasms · Lymphatic Metastasis · Mast-Cell Sarcoma · Rats · Rats, Wistar · Rodent Diseases
[Abstract]

6 Disposition of 14C-erythritol in germfree and conventional rats
article 1996    
Author: Ommen, B. van · Bie, B. de · Bar, A.
Keywords: Toxicology · erythritol · carbon · carbon dioxide · diagnostic agent · sweetening agent · animal experiment · article · controlled study · drug disposition · drug elimination · drug metabolism · female · germfree animal · male · nonhuman · priority journal · rat · absorption · animal · body weight · intestine · kidney · metabolism · microbiology · physiology · tissue distribution · urine · Wistar rat · Absorption · Animals · Body Weight · Carbon Dioxide · Carbon Radioisotopes · Erythritol · Female · Germ-Free Life · Intestines · Kidney · Male · Rats · Rats, Wistar · Sweetening Agents · Tissue Distribution
[Abstract]

7 Differential effects of 17α-ethinylestradiol on the neutral and acidic pathways of bile salt synthesis in the rat
article 1999    
Author: Koopen, N.R. · Post, S.M. · Wolters, H. · Havinga, R. · Stellaard, F. · Boverhof, R. · Kuipers, F. · Princen, H.M.G.
Keywords: Δ-<sup>22</sup>-β-muricholate · Bile · Cholestasis · Cholesterol-7α- hydroxylase · Enterohepatic circulation · Estrogens · Sterol-27-hydroxylase · Wistar rat · Animals · Aryl Hydrocarbon Hydroxylases · Bile Acids and Salts · Chenodeoxycholic Acid · Cholates · Cholesterol 7-alpha-Hydroxylase · Cytochrome P-450 CYP27A1 · Cytochrome P-450 Enzyme System · Enterohepatic Circulation · Ethinyl Estradiol · Hydrogen-Ion Concentration · Liver · Male · Rats · Rats, Wistar · RNA, Messenger · Steroid 12-alpha-Hydroxylase · Steroid Hydroxylases
[PDF] [Abstract]

8 Comparative in vitro-in vivo percutaneous penetration of the fungicide ortho-phenylphenol
article 2002    
Author: Cnubben, N.H.P. · Elliott, G.R. · Hakkert, B.C. · Meuling, W.J.A. · Sandt, J.J.M. van de
Keywords: Health · Dermal penetration · In vitro-in vivo comparison · Ortho-phenylphenol · Risk assessment · 2 hydroxybiphenyl · 2-phenylphenol · Biphenyl derivative · Fungicide · Animal tissue · Biotransformation · Controlled study · Human · Human tissue · In vitro study · In vivo study · Male · Nonhuman · Skin absorption · Skin culture · Skin penetration · Thickness · Toxicokinetics · Urinary excretion · Adult · Animal · Comparative study · Dose response · Epidermis · Intradermal drug administration · Membrane · Metabolism · Outbred strain · Permeability · Swine · Wistar rat · Administration, Cutaneous · Adult · Animal · Animals, Outbred Strains · Biphenyl Compounds · Comparative Study · Dose-Response Relationship, Drug · Epidermis · Female · Fungicides, Industrial · Human · In Vitro · Male · Membranes · Permeability · Rats · Rats, Wistar · Skin Absorption · Support, Non-U.S. Gov't · Swine · Animals · Humans · Sus scrofa
[Abstract]

9 Ninety-day oral toxicity study of lycopene from Blakeslea trispora in rats
article 2003    
Author: Jonker, D. · Kuper, C.F. · Fraile, N. · Estrella, A. · Rodríguez Otero, C.
Keywords: Toxicology · Toxicology and Applied Pharmacology · Diet · Lycopene · NOEL · Oral · Subchronic toxicity · Wistar rat · lycopene · animal experiment · animal tissue · article · blood examination · body weight · calculation · clinical chemistry · clinical observation · cognition · dietary intake · female · food intake · functional assessment · fungal biomass · histopathology · male · motor activity · nonhuman · ophthalmoscope · organ weight · priority journal · rat · urinalysis · Administration, Oral · Animals · Antioxidants · Behavior, Animal · Biomass · Body Weight · Carotenoids · Chemistry, Clinical · Diet · Dose-Response Relationship, Drug · Female · Hematologic Tests · Male · Motor Activity · Mucorales · No-Observed-Adverse-Effect Level · Rats · Rats, Wistar · Blakeslea trispora · Helianthus · Rattus norvegicus
[Abstract]

10 Disposition of 14C-α-cyclodextrin in germ-free and conventional rats
article 2004    
Author: Ommen, B. van · Bie, A.T.H.J. de · Bär, A.
Keywords: Biology · Physiological Sciences · alpha cyclodextrin · carbon 14 · alpha cyclodextrin derivative · alpha-cyclodextrin · carbon · cyclodextrin · animal experiment · animal tissue · article · blood analysis · carcass · controlled study · dietary fiber · female · fermentation · gastrointestinal tract · germfree animal · high performance liquid chromatography · intestine flora · isotope labeling · kidney tubule excretion · lung alveolus carbon dioxide tension · male · metabolic regulation · nonhuman · priority journal · radioisotope distribution · rat · rat strain · small intestine absorption · species comparison · stomach content · animal · blood · drug detoxification · intravenous drug administration · oral drug administration · tissue distribution · urine · Wistar rat · Mammalia · Microbiota · Rattus norvegicus · Administration, Oral · alpha-Cyclodextrins · Animals · Carbon Radioisotopes · Cyclodextrins · Female · Germ-Free Life · Injections, Intravenous · Male · Metabolic Detoxication, Drug · Rats · Rats, Wistar · Tissue Distribution
[Abstract]

11 Pathological and immunological effects of respirable coal fly ash in male Wistar rats
article 1999    
Author: Dormans, J.A.M.A. · Steerenberg, P.A. · Arts, J.H.E. · Bree, L. van · Klerk, A. de · Verlaan, A.P.J. · Bruijntjes, J.P. · Beekhof, P. · Soolingen, D. van · Loveren, H. van
Keywords: Nutrition · carbon · coal · immunoglobulin · air pollutant · air quality control · animal · article · B lymphocyte · biosynthesis · blood analysis · body weight · cytology · drug effect · exposure · fly ash · immunology · industrial waste · lung · lung lavage · male · natural killer cell · Netherlands · organ size · particulate matter · pathology · phagocytosis · rat · risk assessment · serum bactericidal activity · T lymphocyte · Wistar rat · Air Pollutants, Occupational · Animals · Atmosphere Exposure Chambers · B-Lymphocytes · Blood Bactericidal Activity · Blood Chemical Analysis · Body Weight · Bronchoalveolar Lavage Fluid · Carbon · Coal · Immunoglobulins · Industrial Waste · Inhalation Exposure · Killer Cells, Natural · Lung · Male · Netherlands · Organ Size · Particulate Matter · Phagocytosis · Rats · Rats, Wistar · Risk Assessment · T-Lymphocytes · Animalia · Listeria · Rattus norvegicus
[Abstract]

12 Intracerebroventricular administration of neuropeptide Y induces hepatic insulin resistance via sympathetic innervation
article 2008    
Author: Hoek, A.M. van den · Heijningen, C. van · Schröder - Elst, J.P. van der · Ouwens, D.M. · Havekes, L.M. · Romijn, J.A. · Kalsbeek, A. · Pijl, H.
Keywords: corticosterone · glucose · insulin · liothyronine · neuropeptide Y · testosterone · thyroxine · antidiabetic agent · animal experiment · animal model · animal tissue · article · controlled study · drug mechanism · glucose metabolism · hormone blood level · insulin resistance · liver · male · nonhuman · parasympathetic innervation · priority journal · rat · sympathetic innervation · adrenergic system · animal · drug effect · glucose blood level · glucose clamp technique · hyperinsulinism · innervation · intracerebroventricular drug administration · metabolism · pathophysiology · physiology · sympathectomy · vagotomy · Wistar rat · Animals · Blood Glucose · Glucose Clamp Technique · Hyperinsulinism · Hypoglycemic Agents · Injections, Intraventricular · Insulin · Insulin Resistance · Liver · Male · Neuropeptide Y · Parasympathectomy · Rats · Rats, Wistar · Sympathectomy · Sympathetic Nervous System
[Abstract]

13 Disposition of [14C]γ-cyclodextrin in germ-free and conventional rats
article 1998    
Author: Bie, A.T.H.J. de · Ommen, B. van · Bär, A.
Keywords: Nutrition · Carbon 14 · Carbon dioxide · Drug metabolite · Gamma cyclodextrin · Carbon · Cyclodextrin · Gamma cyclodextrin derivative · Gamma-cyclodextrin · Animal experiment · Animal tissue · Carcass · Controlled study · Dose response · Drug bile level · Drug blood level · Drug disposition · Drug feces level · Drug identification · Drug metabolism · Drug saliva level · Drug tissue level · Drug urine level · Female · Gastrointestinal tract · Germfree animal · High performance liquid chromatography · Intravenous drug administration · Isotope labeling · Male · Nonhuman · Oral drug administration · Priority journal · Rat · Animal · Animal food · Bile · Breath analysis · Chemistry · Comparative study · Digestive system · Feces · Intestine absorption · Metabolism · Wistar rat · Administration, Oral · Animal Feed · Animals · Breath Tests · Carbon Dioxide · Carbon Radioisotopes · Cyclodextrins · Digestive System · Feces · Female · gamma-Cyclodextrins · Germ-Free Life · Injections, Intravenous · Intestinal Absorption · Male · Rats · Rats, Wistar
[Abstract]

14 Developmental immunotoxicity of ethanol in an extended one-generation reproductive toxicity study
article 2013    
Author: Tonk, E.C.M. · Groot, D.M.G. de · Wolterbeek, A.P.M. · Penninks, A.H. · Waalkens-Berendsen, I.D.H. · Piersma, A.H. · Loveren, H. van
Keywords: Biology · Benchmark dose approach · Developmental immunotoxicity · Ethanol · Extended one-generation reproductive toxicity study · Alcohol · Concanavalin A · Drinking water · Keyhole limpet hemocyanin · Lipopolysaccharide · Nitric oxide · Tumor necrosis factor alpha · Adaptive immunity · Adult animal · Animal experiment · Animal model · blood cell · Cell adhesion · Cell proliferation · Cell stimulation · Cell subpopulation · Chemical parameters · Controlled study · Cytokine production · Developmental parameters · Developmental toxicity · Female · Immune response · Immunization · Immunological parameters · Immunomodulation · Immunotoxicity · Innate immunity · Lactation · Male · Mating · Medical parameters · Perinatal period · Priority journal · Rat · Reproductive toxicity · Spleen cell · Toxicity testing · Wistar rat · Rattus norvegicus · Biomedical Innovation · Healthy Living · Life Triskelion BV · QS - Quality & Safety TARA - Toxicology and Risk Assessment RAPID - Risk Analysis for Products in Development · EELS - Earth, Environmental and Life Sciences TNO Bedrijven
[Abstract]

15 Therapeutic efficacy of the adenosine A1 receptor agonist N6-cyclopentyladenosine (CPA) against organophosphate intoxication
article 2002    
Author: Bueters, T.J.H. · Groen, B. · Danhof, M. · IJzerman, A.P. · Helden, H.P.M. van
Keywords: Biology · Acetylcholine release · Adenosine A1 receptor · N6-Cyclopentyladenosine · Organophosphate · Adenosine A1 receptor agonist · Adenosine receptor stimulating agent · Cyclohexyladenosine · Methylphosphonothioic acid s (2 diisopropylaminoethyl) o ethyl ester · Adenosine receptor · Cholinesterase · Drug derivative · N(6) cyclopentyladenosine · Organophosphate · Phosphorothioic acid derivative · Bioaccumulation · Cholinergic system · Concentration response · Controlled study · Corpus striatum · Crug efficacy · Enzyme activity · Hippocampus · Intoxication · Male · Microdialysis · Nonhuman · Rat · Reduction · Animal · Drug potentiation · Enzymology · Metabolism · Secretion · Wistar rat · Animals · Cholinesterase Inhibitors · Cholinesterases · Corpus Striatum · Male · Microdialysis · Organothiophosphorus Compounds · Parathion · Phosphoric Acid Esters · Rats · Rats, Wistar · Receptors, Purinergic P1 · Sarin · Acetylcholinesterase, 9000-81-1 · Cyclohexyladenosine, 36396-99-3 · Methylphosphonothioic acid s (2 diisopropylaminoethyl) o ethyl ester, 50782-69-9 · Parathion, 3270-86-8, 56-38-2, 597-88-6 · Sarin, 107-44-8; tabun, 77-81-6 · Acetylcholine, 51-84-3 · Adenosine, 58-61-7; · Cholinesterase Inhibitors · Cholinesterases, EC 3.1.1.8 · N(6)-cyclopentyladenosine, 41552-82-3 · Organothiophosphorus Compounds · Parathion, 56-38- · Phosphoric Acid Esters · Receptors, Purinergic P1 · Sarin, 107-44-8 · Tabun, 77-81-6 · VX, 50782-69-9
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 15 of 15 found. | Sort by date