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1 Prediction of in vivo embryotoxic effect levels with a combination of in vitro studies and PBPK modelling
article 2006    
Author: Verwei, M. · Burgsteden, J.A. van · Krul, C.A.M. · Sandt, J.J.M. van de · Freidig, A.P.
Keywords: Biology · Biomedical Research · Alternative test method · Developmental toxicity · Embryonic stem cells · PBPK model · 2 ethoxyethanol · 2 methoxyethanol · acetic acid derivative · ethoxyacetic acid · fluorouracil · methotrexate · methoxyacetic acid · retinoic acid · unclassified drug · animal cell · article · computer model · controlled study · embryo · embryo development · embryonic stem cell · embryotoxicity · exposure · metabolism · mouse · nonhuman · prediction · priority journal · risk assessment · rodent · Animal Testing Alternatives · Animals · Cell Line · Cell Survival · Dose-Response Relationship, Drug · Embryo · Mice · Models, Biological · Predictive Value of Tests · Rats · Risk Assessment · Stem Cells · Teratogens · Toxicity Tests · Rodentia
[Abstract]

2 Free and total urinary 2-butoxyacetic acid following dermal and inhalation exposure to 2-butoxyethanol in human volunteers
article 2004    
Author: Kezic, S. · Meuling, W.J.A. · Jakasa, I.
Keywords: Health · Physiological Sciences · 2-Butoxyacetic acid · 2-Butoxyethanol · Dermal exposure · Skin absorption · 2 butoxyacetic acid · 2 butoxyethanol · acetic acid derivative · biochemical marker · unclassified drug · adult · aqueous solution · article · blood level · calculation · conjugation · controlled study · dermis · environmental exposure · forearm · half life time · human · human experiment · inhalation · kinetics · male · mouth · normal human · sampling · urinalysis · urinary excretion · urine level · volunteer · Administration, Cutaneous · Administration, Inhalation · Adult · Ethylene Glycols · Glycolates · Half-Life · Humans · Male · Middle Aged · Skin Absorption
[Abstract]

3 Decrease of intracellular pH as possible mechanism of embryotoxicity of glycol ether alkoxyacetic acid metabolites
article 2010    
Author: Louisse, J. · Bai, Y. · Verwei, M. · Sandt, J.J.M. van de · Blaauboer, B.J. · Rietjens, I.M.C.M.
Keywords: Biology · Biomedical Research · BALB/c-3T3 cells · Embryonic stem cells · Embryotoxicity · Glycol ethers · Intracellular pH · Mechanism · acetazolamide · acetic acid derivative · alkoxyacetic acid glycol ether derivative · amiloride · butoxyacetic acid · ethoxyacetic acid · fluorouracil · methoxyacetic acid · phenoxyacetic acid · retinoic acid · unclassified drug · valproic acid · acidification · animal cell · animal cell culture · article · cell differentiation · cell pH · cell strain 3T3 · controlled study · embryonic stem cell · embryotoxicity · metabolite · mouse · nonhuman · pH measurement · Acetazolamide · Acetic Acids · Animals · BALB 3T3 Cells · Cell Differentiation · Embryo, Mammalian · Embryonic Stem Cells · Ethylene Glycols · Glycolates · Hydrogen-Ion Concentration · Intracellular Fluid · Mice · Teratogens · Valproic Acid
[Abstract]

4 Prenatal developmental toxicity study with 7-hydroxymatairesinol potassium acetate (HMRlignan) in rats
article 2004    
Author: Wolterbeek, A.P.M. · Roberts, A. · Korte, H. · Unkila, M. · Waalkens-Berendsen, D.H.
Keywords: Toxicology · Toxicology and Applied Pharmacology · 7 hydroxymatairesinol potassium acetate · acetic acid derivative · enterolactone · lignan derivative · unclassified drug · animal experiment · article · body weight · controlled study · corpus luteum · diet · dose response · drug dose regimen · female · fertility · fetus development · fetus resorption · food intake · gestation period · male · nonhuman · palatability · prenatal development · priority journal · rat · sex ratio · skeleton malformation · toxicity testing · Administration, Oral · Animal Feed · Animals · Animals, Outbred Strains · Chemistry, Pharmaceutical · Eating · Female · Fetus · Lignans · Male · Maternal Exposure · Molecular Structure · No-Observed-Adverse-Effect Level · Potassium Acetate · Pregnancy · Rats · Reproduction · Seeds · Sesamum · Animalia · Mammalia · Rattus norvegicus
[Abstract]

5 Modification and re-validation of the ethyl acetate-based multi-residue method for pesticides in produce
article 2007    
Author: Mol, H.G.J. · Rooseboom, A. · Dam, R. van · Roding, M. · Arondeus, K. · Sunarto, S.
Keywords: Agriculture Chemistry · Analytical research · Foods/Beverages · GC-MS · LC-MS/MS · Multi-residue analysis · Pesticides · Amines · Carbon black · Degradation · Extraction · Fruits · Gas chromatography · Liquid chromatography · Mass spectrometry · Ethyl acetate · Limits of quantification · Multi-residue analysis · Solid phase extraction · Pesticides · acetic acid derivative · acetic acid ethyl ester · amine · carbon · pesticide residue · article · chemistry · food contamination · gas chromatography · liquid chromatography · methodology · plant · reproducibility · sensitivity and specificity · solid phase extraction · tandem mass spectrometry · Acetates · Amines · Carbon · Chromatography, Gas · Chromatography, Liquid · Food Contamination · Pesticide Residues · Plants, Edible · Reproducibility of Results · Sensitivity and Specificity · Solid Phase Extraction · Tandem Mass Spectrometry
[Abstract]

6 Linking phylogenetic identities of bacteria to starch fermentation in an in vitro model of the large intestine by RNA-based stable isotope probing
article 2009    
Author: Kovatcheva-Datchary, P. · Egert, M. · Maathuis, A. · Rajilić-Stojanović, M. · Graaf, A.A.de · Smidt, H. · Vos, W.M.de · Venema, K.
Keywords: Biology · biomedical research · acetic acid derivative · bacterial DNA · bacterial RNA · butyric acid derivative · isotope · propionic acid derivative · ribosome DNA · RNA 16S · starch · article · bacterium · chemistry · classification · DNA fingerprinting · DNA sequence · fermentation · genetics · growth, development and aging · human · in vitro study · large intestine · metabolism · microbiology · molecular genetics · nucleotide sequence · phylogeny · restriction fragment length polymorphism · RNA gene · sequence homology · staining · Acetates · Bacteria · Butyrates · DNA Fingerprinting · DNA, Bacterial · DNA, Ribosomal · fermentation · genes, rRNA · humans · large intestine · isotopes · molecular sequence data · phylogeny · polymorphism · restriction fragment length · propionates · bacterial RNA · ribosomal RNA 16S · sequence analysis DNA · sequence homology · nucleic acid · staining and labeling · starch · bacteria (microorganisms) · bifidobacterium adolescentis · eubacterium rectale · prevotella · ruminococcus · ruminococcus bromii
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 6 of 6 found. | Sort by date