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1 Monolayers of IEC-18 cells as an in vitro model for screening the passive transcellular and paracellular transport across the intestinal barrier: Comparison of active and passive transport with the human colon carcinoma Caco-2 cell line
article 2002    
Author: Versantvoort, C.H.M. · Ondrewater, R.C.A. · Duizer, E. · Sandt, J.J.M. van de · Gilde, A.J. · Groten, J.P.
Keywords: Caco-2 · Carrier-mediated transport · H+-di/tripeptide carrier · IEC-18 · Intestinal cell lines · MRP · P-Glycoprotein · acetylsalicylic acid · calcein · carrier protein · dinitrophenylglutathione · glucose derivative · glutathione derivative · glycoprotein P · glycylsarcosine · hydrocortisone · macrogol 4000 · mannitol · methylglucose · multidrug resistance protein · probenecid · propranolol · rhodamine 123 · salicylic acid · testosterone · unclassified drug · verapamil · vincristine · animal cell · article · cell membrane permeability · cell strain CACO 2 · cell transport · colon carcinoma · controlled study · drug transport · human · human cell · in vitro study · ion transport · model · nonhuman · priority journal · protein expression · rat · screening
[Abstract]

2 Aspirin reduces hypertriglyceridemia by lowering VLDL-triglyceride production in mice fed a high-fat diet
article 2011    
Author: Diepen, J.A. van · Vroegrijk, I.O.C.M. · Berbée, J.F.P. · Shoelson, S.E. · Romijn, J.A. · Havekes, L.M. · Rensen, P.C.N. · Voshol, P.J.
Keywords: Biology · Inflammation · Lipid metabolism · Very low-density lipoprotein · acetylsalicylic acid · apolipoprotein C1 · immunoglobulin enhancer binding protein · transcription factor RelA · triacylglycerol · very low density lipoprotein cholesterol · animal experiment · animal model · article · cholesterol blood level · controlled study · drug mechanism · drug targeting · enzyme inhibition · gene expression · hypertriglyceridemia · in vivo study · lipid diet · lipogenesis · lipoprotein blood level · male · metabolic syndrome X · mouse · nonhuman · priority journal · protein expression · risk factor · triacylglycerol blood level · aspirin · Healthy Living · Life · MHR - Metabolic Health Research · EELS - Earth, Environmental and Life Sciences
[Abstract]

3 Oxidation of LDL and extent of peripheral atherosclerosis
article 1999    
Author: Vijver, L.P.L. van de · Kardinaal, A.F.M. · Duyvenvoorde, W. van · Kruijssen, D.A.C.M. · Grobbee, D.E. · Poppel, G. van · Princen, H.M.G.
Keywords: Biology · Ankle-arm index · LDL composition · LDL oxidation · Peripheral atherosclerosis · Resistance time · Acetylsalicylic acid · Antihypertensive agent · Copper · Coumarin derivative · High density lipoprotein cholesterol · Low density lipoprotein · Low density lipoprotein cholesterol · Triacylglycerol · Adult · Aged · Arm · Atherosclerosis · Cholesterol blood level · Diet · Disease severity · Drug use · Human · Leg · Aged · Aged, 80 and over · Anticoagulants · Antihypertensive Agents · Arteriosclerosis · Aspirin · Cholesterol, Dietary · Coumarins · Diet, Fat-Restricted · Humans · Lipid Peroxidation · Lipoproteins, LDL · Male · Middle Aged · Odds Ratio · Risk Factors
[Abstract]

4 Use of factorial designs in combination toxicity studies
article 1996    
Author: Groten, J.P. · Schoen, E.D. · Feron, V.J.
Keywords: Toxicology · Acetylsalicylic acid · Butylated hydroxyanisole · Cadmium · Calcium · Chemical agent · Dichloromethane · Formaldehyde · Iron · Loperamide · Magnesium · Manganese · Mineral · Phosphorus · Phthalic acid bis(2 ethylhexyl) ester · Phthalic acid derivative · Phthalic acid ester · Polycyclic aromatic hydrocarbon · Selenium · Sermine · Sannous chloride · Tace element · Zinc · Animal experiment · Bioaccumulation · Carcinogenic activity · Chemical interaction · Controlled study · Drug mixture · Economic aspect · Factorial analysis · Administration, Oral · Alanine Transaminase · Analysis of Variance · Animals · Aspartate Aminotransferases · Body Weight · Cadmium · Drug Interactions · Kidney · Liver · Male · Minerals · Models, Chemical · Rats · Rats, Wistar · Toxicology · Xenobiotics
[Abstract]

5 Subacute toxicity of a mixture of nine chemicals in rats: Detecting interactive effects with a fractionated two-level factorial design
article 1997    
Author: Groten, J.P. · Schoen, E.D. · Bladeren, P.J. van · Kuper, C.F. · Zorge, J.A. van · Feron, V.J.
Keywords: Acetylsalicylic acid · Butylated hydroxyanisole · Cadmium chloride · Dichloromethane · Formaldehyde · Loperamide · Phthalic acid bis(2 ethylhexyl) ester · Spermine · Stannous chloride · Animal experiment · Controlled study · Drug mixture · Factorial analysis · Male · Model · Nonhuman · Oral drug administration · Prognosis · Rat · Risk assessment · Theory · Toxicity · Administration, Inhalation · Animals · Blood Chemical Analysis · Body Weight · Drug Combinations · Drug Interactions · Epithelium · Hazardous Substances · Hematologic Tests · Hypertrophy · Liver · Male · Models, Statistical · Multiple Chemical Sensitivity · Nasal Cavity · No-Observed-Adverse-Effect Level · Organ Size · Rats · Rats, Wistar
[Abstract]

6 A high throughput screening system for predicting chemically-induced reproductive organ deformities
article 2015    
Author: Burg, B. van der · Pieterse, B. · Rorije, E. · Lewin, G. · Linden, S.C. van der · Man, H.Y. · Piersma, A.H. · Mangelsdorf, I. · Wolterbeek, A.P.M. · Kroese, E.D. · Vugt-Lussenburg, B.M.A. van
Keywords: Nutrition · High throughput screening · Reproductive organ deformities · Estrogen–androgen reporter gene assay · Mechanistic validation · 2 ethylhexanoic acid · 2 methoxyethanol · 2,4 dextro isopropylamine salt · 2,4 pyrimethamine · Acetylsalicylic acid · Androgen receptor · Benomyl · Bis(trichloromethyl)sulfone · Carbamazepine · Carbendazim · Cellosolve acetate · Cyanazine · Cyproconazole · Di(n hexyl)phthalate · Dibutyltindichloride · Diglyme · Fenachlorazol ethyl · Glycolic acid · Halosulfuron methyl · Mancozeb · Molinate · Pentachlorophenol · Phthalic acid benzyl butyl ester · Prothioconazole · Toxic substance · Triclopyr · Unclassified drug · Animal experiment · Animal model · Controlled study · Estrogen activity · Genital malformation · Nonhuman · Prediction · Rat · Reporter gene · Reproductive toxicity · Toxicity testing · Food and Nutrition · Healthy Living · Life · RAPID - Risk Analysis for Products in Development · ELSS - Earth, Life and Social Sciences
[Abstract]

7 Early spontaneous intermittent myocardial reperfusion during acute myocardial infarction is associated with augmented thrombogenic activity and less myocardial damage
article 1995    
Author: Haider, A.W. · Andreotti, F. · Hackett, D.R. · Tousoulis, D. · Kluft, C. · Maseri, A. · Davies, G.J.
Keywords: Biology · acetylsalicylic acid · alteplase · c reactive protein · creatine kinase mb · diltiazem · fibrin · heparin · tissue plasminogen activator · acute heart infarction · adult · aged · angiocardiography · article · clinical trial · controlled clinical trial · controlled study · coronary artery thrombosis · female · heart muscle injury · heart ventriculography · human · intravenous drug administration · major clinical study · male · oral drug administration · priority journal · reperfusion · thrombogenesis · Analysis of Variance · Chi-Square Distribution · Coronary Angiography · Coronary Circulation · Coronary Thrombosis · Creatine Kinase · Electrocardiography, Ambulatory · Enzyme Tests · Female · Heart Ventricles · Hemostasis · Humans · Isoenzymes · Male · Middle Aged · Myocardial Infarction · Myocardial Reperfusion Injury · Statistics, Nonparametric · Thrombolytic Therapy · Time Factors
[Abstract]

8 Moderate alcohol consumption reduces plasma C-reactive protein and fibrinogen levels : a randomized, diet-controlled intervention study
article 2002    
Author: Sierksma, A. · Gaag, M.S. van der · Kluft, C. · Hendriks, H.F.J.
Keywords: Nutrition · Alcohol · Atherosclerosis · C-reactive protein · Fibrinogen · Inflammation · Acetylsalicylic acid · Acute phase protein · Alanine aminotransferase · Aspartate aminotransferase · Estradiol · Follitropin · Gamma glutamyltransferase · Glucose · Hemoglobin · High density lipoprotein cholesterol · Low density lipoprotein cholesterol · Paracetamol · Triacylglycerol · Adult · Alcohol consumption · Antiinflammatory activity · Cardiovascular risk · Cigarette smoking · Clinical trial · Controlled clinical trial · Controlled study · Crossover procedure · Diet therapy · Fibrinogen blood level · Food composition · Human experiment · Netherlands · Postmenopause · Protein blood level · Randomized controlled trial · Alcohol Drinking · Beer · C-Reactive Protein · Cardiovascular Diseases · Cholesterol, HDL · Cross-Over Studies · Diet · Female · Humans · Liver · Male · Middle Aged · Postmenopause · Triglycerides
[Abstract]

9 PAF-acether-induced release of tissue-type plasminogen activator from vessel walls
article 1985    
Author: Emeis, J.J. · Kluft, C.
Keywords: Biology · 3 amino 1 (3 trifluoromethylphenyl) 2 pyrazoline · 4 bromophenacyl bromide · Acetylsalicylic acid · Diethylcarbamazine · Docebenone · Endetic acid · Indometacin · Mepacrine · Nordihydroguaiaretic acid · Plasminogen activator · Thrombocyte activating factor · Tissue plasminogen activator · Animal experiment · Biological model · Blood and hemopoietic system · Blood clotting · Blood vessel wall · Cardiovascular system · Dose response · Drug accumulation · Drug analysis · Drug blood level · Drug comparison · Drug determination · Drug identification · Drug inhibition · Drug isolation · Drug mechanism · Drug response · Histology · Intravenous drug administration · Nonhuman · Peripheral vascular system · Regional perfusion · Spectrophotometry · Thrombocyte aggregating factor · Animal · Blood Vessels · Calcium · Cyclooxygenase Inhibitors · Fibrinolysis · Lipoxygenase Inhibitors · Male · Phospholipases · Plasminogen Activators · Platelet Activating Factor · Rats · Rats, Inbred Strains · Support, Non-U.S. Gov't
[Abstract]

10 Current PTCA practice and clinical outcomes in the Netherlands: The real world in the pre-drug-eluting stent era
article 2004    
Author: Agema, W.R.P. · Monraats, P.S. · Zwinderman, A.H. · Winter, R.J. de · Tio, R.A. · Doevendans, P.A.F.M. · Waltenberger, J. · Maat, M.P.M. de · Frants, R.R. · Atsma, D.E. · Laarse, A. van der · Wall, E.E. van der · Jukema, J.W.
Keywords: Biology · Biomedical Research · Percutaneous transluminal coronary angioplasty · Restenosis · acetylsalicylic acid · clopidogrel · fibrinogen receptor antagonist · ticlopidine · acute heart infarction · adult · aged · clinical trial · coronary artery bypass graft · diabetes mellitus · drug eluting stent · follow up · heart death · heart disease · hypertension · interventional cardiovascular procedure · major clinical study · multicenter study · peripheral vascular disease · practice guideline · restenosis · revascularization · risk factor · stable angina pectoris · transluminal coronary angioplasty · treatment outcome · Angioplasty, Transluminal, Percutaneous Coronary · Coronary Restenosis · Drug Implants · Female · Follow-Up Studies · Humans · Male · Middle Aged · Myocardial Revascularization · Netherlands · Professional Practice · Prospective Studies · Risk Factors · Stents · Treatment Outcome
[Abstract]

11 The role of cyclooxygenase in n-6 and n-3 polyunsaturated fatty acid mediated effects on cell proliferation, PGE2 synthesis and cytotoxicity in human colorectal carcinoma cell lines
article 2003    
Author: Dommels, Y.E.M. · Haring, M.M.G. · Keestra, N.G.M. · Alink, G.M. · Bladeren, P.J. van · Ommen, B. van
Keywords: Biology · Analytical research · 5 (4 fluorophenyl) 1 [(4 methylsulfonyl)phenyl] 3 trifluoromethylpyrazole · 5,8,11,14,17 icosapentaenoic acid · acetylsalicylic acid · alpha tocopherol · antioxidant · arachidonic acid · ascorbic acid · carbene · celecoxib · cyclooxygenase 2 inhibitor · docosahexaenoic acid · indometacin · interleukin 1beta · linoleic acid · malonaldehyde · nonsteroid antiinflammatory agent · omega 3 fatty acid · omega 6 fatty acid · prostaglandin E2 · prostaglandin synthase · antineoplastic activity · cancer cell · cell growth · cell proliferation · colon cancer · colorectal carcinoma · controlled study · cytotoxicity · drug effect · drug mechanism · enzyme activation · enzyme activity · fatty acid synthesis · growth inhibition · human · human cell · hypothesis · incubation time · lipid peroxidation · priority journal · review · signal transduction · Antioxidants · Caco-2 Cells · Cell Division · Colorectal Neoplasms · Cyclooxygenase Inhibitors · Dinoprostone · Fatty Acids, Omega-3 · Fatty Acids, Omega-6 · Fatty Acids, Unsaturated · HT29 Cells · Humans · Lipid Peroxidation · Prostaglandin-Endoperoxide Synthases
[Abstract]

12 Pharmacological modulation of the endotoxin-induced increase in plasminogen activator inhibitor activity in rats
article 1992    
Author: Emeis, J.J. · Hoogen, C.M. van den
Keywords: 2 (3,4 dihydro 3,4 dioxo 1 naphthylamino)benzoic acid methyl ester · 2,3 diethyl 4 methoxy 1 naphthol acetate · 3 [3 tert butylthio 1 (4 chlorobenzyl) 5 isopropyl 2 indolyl] 2,2 dimethylpropionic acid · 3 amino 1 (3 trifluoromethylphenyl) 2 pyrazoline · Acetylsalicylic acid · Argipressin[1 (3,3 cyclopentamethylene 3 mercaptopropionic acid) 2 (2 methyltyrosine)] · Cycloheximide · Dexamethasone · Diltiazem · Endotoxin · Forskolin · Ginkgolide b · Heparin · Hirudin · Indometacin · Isobutylmethylxanthine · Mepyramine maleate · n (3 phenoxy 3 phenylallyl)acetohydroxamic acid · n [3 (3 phenoxyphenyl)allyl]acetohydroxamic acid · n(g) nitroarginine methyl ester · Naloxone · Phentolamine · Phentolamine mesylate · Propranolol · Unclassified drug · Verapamil · Animal experiment · Controlled study · Fibrinolysis · Intraperitoneal drug administration · Intravenous drug administration · Nonhuman · Oral drug administration · Pharmacology · 1-Methyl-3-isobutylxanthine · Animal · Aspirin · BW-755C · Dose-Response Relationship, Drug · Enzyme Activation · Indomethacin · Lipopolysaccharides · Male · Plasminogen Activator Inhibitor 1 · Rats · Rats, Wistar · Tissue Plasminogen Activator
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 12 of 12 found. | Sort by date