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1 Role of apoCs in lipoprotein metabolism : Functional differences between ApoC1, ApoC2, and ApoC3
article 1999    
Author: Jong, M.C. · Hofker, M.H. · Havekes, L.M.
Keywords: Biology · Apolipoproteins · Lipoprotein lipase · Lipoproteins, VLDL · Mice, transgenic · Animals · Apolipoprotein C-I · Apolipoprotein C-II · Apolipoprotein C-III · Apolipoproteins C · Humans · Lipoproteins · Mice · Mice, Transgenic · Mutation
[Abstract]

2 Hyperlipidemia and cutaneous abnormalities in transgenic mice overexpressing human apolipoprotein C1
article 1998    
Author: Jong, M.C. · Gijbels, M.J.J. · Dahlmans, V.E.H. · Gorp, P.J.J. van · Koopman, S.-J. · Ponec, M. · Hofker, M.H. · Havekes, L.M.
Keywords: Health · Apolipoprotein C · Hypertriglyceridemia · Sebaceous glands · Sebum production · Triglycerides · Animals · Apolipoprotein C-I · Apolipoproteins C · Epidermis · Female · Humans · Hyperlipidemias · Lipids · Male · Mice · Mice, Inbred C57BL · Mice, Transgenic · Skin Abnormalities
[Abstract]

3 Wet-wrap treatment using dilutions of tacrolimus ointment and fluticasone propionate cream in human APOC1 (+/+) mice with atopic dermatitis
article 2009    
Author: Oranje, A.P. · Verbeek, R. · Verzaal, P. · Haspels, I. · Prens, E. · Nagelkerken, L.
Keywords: Biology · Biomedical Research · Apolipoprotein C · Atopic dermatitis · Mouse model · Transepidermal water loss · Wet-wrap treatment · apolipoprotein C1 · fluticasone propionate · tacrolimus · animal experiment · animal model · animal tissue · article · atopic dermatitis · clinical feature · controlled study · disease severity · drug effect · drug formulation · histopathology · mouse · nonhuman · occlusive dressing · priority journal · skin water loss · skinfold thickness · treatment response · weight reduction · Androstadienes · Animals · Apolipoprotein C-I · Bandages · Dermatitis, Atopic · Disease Progression · Dose-Response Relationship, Drug · Emollients · Humans · Mice · Mice, Transgenic · Models, Animal · Ointments · Tacrolimus
[Abstract]

4 Apolipoprotein CI knock-out mice display impaired memory functions
article 2011    
Author: Berbée, J.F.P. · Abildayeva, K. · Blokland, A. · Jansen, P.J. · Lütjohann, D. · Gautier, T. · Sijbrands, E. · Prickaerts, J. · Hadfoune, M. · Ramaekers, F.C.S. · Kuipers, F. · Rensen, P.C.N.
Keywords: Health · APOC1 · Apolipoprotein C-I · Cholesterol · Cognition and brain · Memory · Life · MHR - Metabolic Health Research · EELS - Earth, Environmental and Life Sciences
[Abstract]

5 Development of atopic dermatitis in mice transgenic for human apolipoprotein C1
article 2008    
Author: Nagelkerken, L. · Verzaal, P. · Lagerweij, T. · Persoon-Deen, C. · Berbee, J.F.P. · Prens, E.P. · Havekes, L.M. · Oranje, A.P.
Keywords: Biology · Physiological Sciences · apolipoprotein C1 · corticosteroid · immunoglobulin E · animal tissue · article · atopic dermatitis · controlled study · histopathology · inflammatory cell · lichenoid eruption · lipid metabolism · mouse · nonhuman · priority journal · protein expression · Administration, Topical · Adrenal Cortex Hormones · Animals · Apolipoprotein C-I · Dermatitis, Atopic · Eosinophils · Epidermis · Female · Humans · Immunoglobulin E · Liver · Male · Mast Cells · Mice · Mice, Transgenic · Neutrophils · Pruritus
[Abstract]

6 Plasma apolipoprotein CI correlates with increased survival in patients with severe sepsis
article 2008    
Author: Berbée, J.F.P. · Hoogt, C.C. van der · Haas, C.J.C. de · Kessel, K.P.M. van · Dallinga-Thie, G.M. · Romijn, J.A. · Havekes, L.M. · Leeuwen, H.J. van · Rensen, P.C.N.
Keywords: Health · Physiological Sciences · Apolipoprotein · Bacteria · Intensive care · Lipoprotein · Mortality · Sepsis · apolipoprotein A1 · apolipoprotein C1 · apolipoprotein C3 · high density lipoprotein cholesterol · lipid · low density lipoprotein cholesterol · triacylglycerol · adult · article · blood sampling · cholesterol blood level · clinical article · controlled study · correlation analysis · disease severity · female · hospitalization · human · intensive care unit · lipid blood level · male · outcome assessment · prospective study · protein blood level · sepsis · survival · Aged · Apolipoprotein C-I · Biological Markers · Female · Humans · Male · Middle Aged · Prospective Studies · Sepsis · Survival Analysis · Healthy for Life · Healthy Living
[Abstract]

7 Apolipoprotein C-III deficiency accelerates triglyceride hydrolysis by lipoprotein lipase in wild-type and apoE knockout mice
article 2001    
Author: Jong, M.C. · Rensen, P.C.N. · Dahlmans, V.E.H. · Boom, H. van der · Berkel, T.J.C. van · Havekes, L.M.
Keywords: Animals · Apolipoprotein C-III · Apolipoproteins C · Apolipoproteins E · Chylomicrons · Crosses, Genetic · Female · Gene Deletion · Hydrolysis · Lipoprotein Lipase · Lipoproteins, VLDL · Male · Mice · Mice, Inbred C57BL · Mice, Knockout · Time Factors · Triglycerides
[PDF] [Abstract]

8 ApoE2-associated hypertriglyceridemia is ameliorated by increased levels of apoA-V but unaffected by apoC-III deficiency
article 2008    
Author: Gerritsen, G. · Hoogt, C.C. van der · Schaap, F.G. · Voshol, P.J. · Kypreos, K.E. · Maeda, N. · Groen, A.K. · Havekes, L.M. · Rensen, P.C.N. · Dijk, K.W. van
Keywords: Health · Physiological Sciences · Adenovirus-mediated gene transfer · APOE2-knockin mice · Apolipoprotein A-V · Apolipoprotein C-III · Apolipoprotein E2 · Lipoprotein lipase-mediated very low density lipoprotein-triglyceride hydrolysis · apolipoprotein A · apolipoprotein A5 · apolipoprotein B · apolipoprotein C · apolipoprotein C3 · apolipoprotein D · apolipoprotein E · apolipoprotein M · beta2 glycoprotein 1 · clusterin · heparin · Apoa5 protein, mouse · apolipoprotein · Adenovirus · animal experiment · animal model · cholesterol blood level · conference paper · controlled study · disease association · female · gene overexpression · hypertriglyceridemia · in vivo study · lipoprotein deficiency · mouse · nonhuman · stimulation · triacylglycerol blood level · animal · blood · gene transfer · genetics · mouse mutant · physiology · Adenoviridae · Animals · Apolipoprotein C-III · Apolipoprotein E2 · Apolipoproteins · Gene Transfer Techniques · Hypertriglyceridemia · Lipids · Lipoprotein Lipase · Male · Mice · Mice, Knockout
[PDF] [Abstract]

9 Effects of simvastatin on plasma lipids and apolipoproteins in familial hypercholesterolemic swine
article 1996    
Author: Hasler-Rapacz, J. · Kempen, H.J. · Princen, H.M.G. · Kudchodkar, B.J. · Lacko, A. · Rapacz, J.
Keywords: Biology · animal model · apolipoproteins · familial hypercholesterolemia · simvastatin · swine · apolipoprotein a · apolipoprotein b · apolipoprotein c3 · apolipoprotein e · high density lipoprotein cholesterol · hydroxymethylglutaryl coenzyme a reductase · lathosterol · lipid · low density lipoprotein cholesterol · phosphatidylcholine sterol acyltransferase · simvastatin · triacylglycerol · very low density lipoprotein cholesterol · animal experiment · animal model · animal tissue · article · calculation · cholesterol blood level · dose response · enzyme activity · hypercholesterolemia · hyperlipidemia · lipid analysis · lipid blood level · lipoprotein blood level · nonhuman · priority journal · statistical analysis · swine · Animals · Apolipoprotein A-I · Apolipoprotein C-III · Apolipoproteins · Apolipoproteins B · Apolipoproteins C · Apolipoproteins E · Cholesterol · Cholesterol, HDL · Cholesterol, LDL · Enzyme Inhibitors · Female · Hydroxymethylglutaryl-CoA Reductase Inhibitors · Hyperlipoproteinemia Type II · Lipids · Male · Swine · Swine Diseases · Triglycerides
[Abstract]

10 Apolipoprotein CI aggravates atherosclerosis development in ApoE-knockout mice despite mediating cholesterol efflux from macrophages
article 2007    
Author: Westerterp, M. · Eck, M. van · Haan, W. de · Offerman, E.H. · Berkel, T.J.C. van · Havekes, L.M. · Rensen, P.C.N.
Keywords: Biology · Biomedical Research · ApoCI · Cholesterol efflux · Hyperlipidemia · Macrophages · Transgenic mice · Triacylglycerol · Adipose tissue · Aorta root · Artery wall · Atherosclerosis · Protein expression · Statistical significance · Triacylglycerol blood level · Animals · Apolipoprotein C-I · Apolipoproteins E · Atherosclerosis · Bone Marrow Cells · Bone Marrow Transplantation · Cholesterol · Female · Gene Expression Regulation · Liver · Macrophages · Male · Mice · Mice, Knockout · Mice, Transgenic
[Abstract]

11 Hepatic lipid accumulation in apolipoprotein C-I-deficient mice is potentiated by cholesteryl ester transfer protein
article 2007    
Author: Gautier, T. · Tietge, U.J.F. · Boverhof, R. · Perton, F.G. · Le Guern, N. · Masson, D. · Rensen, P.C.N. · Havekes, L.M. · Lagrost, L. · Kuipers, F.
Keywords: Biology · Biomedical Research · Bile · Cholesterol · Triglycerides · bile acid · cholesterol · cholesterol ester transfer protein · high density lipoprotein · triacylglycerol · very low density lipoprotein · animal model · bile secretion · cholesterol blood level · controlled study · insulin metabolism · lipid metabolism · lipid storage · mouse · nonhuman · stress · Animals · Apolipoprotein C-I · Cholesterol Ester Transfer Proteins · Gallbladder · Lipids · Liver · Mice · Mice, Inbred C57BL · Mice, Knockout · Polymerase Chain Reaction · RNA
[PDF] [Abstract]

12 Both lipolysis and hepatic uptake of VLDL are impaired in transgenic mice coexpressing human apolipoprotein E*3Leiden and human apolipoprotein C1
article 1996    
Author: Jong, M.C. · Dahlmans, V.E.H. · Gorp, P.J.J. van · Breuer, M.L. · Mol, M.J.T.M. · Zee, A. van der · Frants, R.R. · Hofker, M.H. · Havekes, L.M.
Keywords: Health · Transgenic mice · Triacylglycerol · Very low density lipoprotein · Animal experiment · Animal model · Atherosclerosis · Cholesterol blood level · Controlled study · Female · Lipolysis · Liver clearance · Liver metabolism · Male · Nonhuman · Protein transport · Transgenic mouse · Triacylglycerol blood level · Animals · Apolipoprotein C-I · Apolipoprotein E3 · Apolipoproteins C · Apolipoproteins E · Arteriosclerosis · Cholesterol · Cholesterol, Dietary · Gene Expression · Humans · Hyperlipoproteinemias · Lipolysis · Lipoproteins, VLDL · Liver · Mice · Mice, Transgenic · Triglycerides
[Abstract]

13 Severe hyperlipidemia in apolipoprotein E2 homozygotes due to a combined effect of hyperinsulinemia and an SstI polymorphism
article 1999    
Author: Sijbrands, E.J.G. · Hoffer, M.J.V. · Meinders, A.E. · Havekes, L.M. · Frants, R.R. · Smelt, A.H.M. · Knijff, P. de
Keywords: Apolipoprotein E · Hyperinsulinemia · Hyperlipoproteinemia type III · Xanthomas · Adult · Aged · Aged, 80 and over · Apolipoprotein A-I · Apolipoprotein C-III · Apolipoprotein E2 · Apolipoproteins A · Apolipoproteins C · Apolipoproteins E · Cholesterol, HDL · Cholesterol, LDL · Cholesterol, VLDL · Family Health · Female · Gene Expression · Haplotypes · Homozygote · Humans · Hyperinsulinism · Hyperlipidemias · Male · Middle Aged · Pedigree · Polymorphism, Single Nucleotide · Promoter Regions (Genetics) · Xanthomatosis
[Abstract]

14 Reduced very-low-density lipoprotein fractional catabolic rate in apolipoprotein C1-deficient mice
article 1997    
Author: Jong, M.C. · Ree, J.H. van · Dahlmans, V.E.H. · Frants, R.R. · Hofker, M.H. · Havekes, L.M.
Keywords: Biology · very low density lipoprotein · animal experiment · catabolism · controlled study · human · hyperlipoproteinemia · lipolysis · metabolism · mouse · nonhuman · priority journal · protein degradation · protein metabolism · transgenic mouse · Animals · Apolipoprotein C-I · Apolipoproteins B · Apolipoproteins C · Cholesterol, Dietary · Female · Lipolysis · Lipoproteins, VLDL · Mice · Mice, Mutant Strains · Triglycerides · Ultracentrifugation · Animalia · Mus musculus
[Abstract]

15 Apolipoprotein CI stimulates the response to lipopolysaccharide and reduces mortality in gram-negative sepsis.
article 2006    
Author: Berbée, J.F. · Hoogt, C.C. van der · Kleemann, R. · Schippers, E.F. · Kitchens, R.L. · Dissel, J.T. van · Bakker-Woudenberg, I.A. · Havekes, L.M. · Rensen, P.C.
Keywords: Biology · Drug effect · Gram negative bacterium · Immunology · Mortality · Mouse · Mouse mutant · Nucleotide sequence · Transgenic mouse · Animals · Antigen Presentation · Apolipoprotein C-I · Apolipoproteins C · Binding Sites · Conserved Sequence · Gram-Negative Bacteria · Humans · Immunity · Inflammation · Lipopolysaccharides · Macrophages · Mice · Mice, Knockout · Mice, Transgenic · Sepsis
[Abstract]

16 Apolipoprotein CI inhibits scavenger receptor BI and increases plasma HDL levels in vivo
article 2008    
Author: Haan, W. de · Out, R. · Berbée, J.F.P. · Hoogt, C.C. van der · Dijk, K.W.v. · Berkel, T.J.C. van · Romijn, J.A. · Wouter Jukema, J. · Havekes, L.M. · Rensen, P.C.N.
Keywords: Health · Physiological Sciences · High density lipoprotein · Oxidized LDL · SR-BI · Transgenic mice · cholesterol ester · high density lipoprotein cholesterol · scavenger receptor BI · Adenovirus · animal cell · cholesterol metabolism · dose response · in vivo study · liver cell · mouse · nonhuman · particle size · protein expression · Adenoviridae · Animals · Apolipoprotein C-I · Cholesterol, HDL · Gene Transfer Techniques · Hepatocytes · Humans · Mice · Mice, Knockout · Scavenger Receptors, Class B · Adenoviridae · Murinae · Mus · Mus musculus
[Abstract]

17 Preoperative apolipoprotein CI levels correlate positively with the proinflammatory response in patients experiencing endotoxemia following elective cardiac surgery
article 2008    
Author: Schippers, E.F. · Berbée, J.F.P. · Disseldorp, I.M. van · Versteegh, M.I.M. · Havekes, L.M. · Rensen, P.C.N. · Dissel, J.T. van
Keywords: Biology · Biomedical Research · Aged · Apolipoprotein C-I · Cardiac Surgical Procedures · Cardiopulmonary Bypass · Cholesterol · Endotoxemia · Female · Humans · Intraoperative Care · Male · Middle Aged · Postoperative Complications · Predictive Value of Tests · Surgical Procedures, Elective · Tumor Necrosis Factor-alpha · ApoCI · Cardiopulmonary bypass · Endotoxemia · Endotoxin · SIRS · TNF-α
[Abstract]

18 Apolipoprotein CI enhances the biological response to LPS via the CD14/TLR4 pathway by LPS-binding elements in both its N- and C-terminal helix
article 2010    
Author: Berbé, J.F.P. · Coomans, C.P. · Westerterp, M. · Romijn, J.A. · Havekes, L.M. · Rensen, P.C.N.
Keywords: Biology · Biomedical Research · Endotoxins · Inflammation · Mice · Peptide · Tnfα · Apolipoprotein C1 · CD14 antigen · Lipopolysaccharide · Lipopolysaccharide binding protein · Toll like receptor 4 · Tumor necrosis factor alpha · Amino terminal sequence · Animal cell · Animal experiment · Carboxy terminal sequence · Controlled study · Cytokine release · Electrophoretic mobility · Mouse · Nonhuman · Peritoneum macrophage · Plasma clearance · Signal transduction
[PDF] [Abstract]

19 Translational research in genomics of Alzheimer's disease: A review of current practice and future perspectives
article 2010    
Author: Mihaescu, R. · Detmar, S.B. · Cornel, M.C. · Flier, W.M. van der · Heutink, P. · Hol, E.M. · Rikkert, M.G.M.O. · Duijn, C.M. van · Janssens, A.C.J.W.
Keywords: Health · Leefomgeving en gezondheid · Alzheimer's disease · genomics · review · translational research · amyloid precursor protein · antidepressant agent · antiinflammatory agent · apolipoprotein C1 · apolipoprotein C2 · apolipoprotein E · bapineuzumab · cholinergic receptor stimulating agent · clathrin assembly protein · clozapine · complement component C3b receptor · cystatin C · disrupted in schizophrenia 1 protein · endothelial nitric oxide synthase · galantamine · growth factor receptor bound protein 2 · growth hormone · mitochondrial transcription factor A · phosphatidylinositol · phosphoenolpyruvate carboxykinase (GTP) · presenilin 1 · presenilin 2 · progranulin · risperidone · rosiglitazone · sortilin · tau protein · transient receptor potential channel 4 · unindexed drug · zinc finger protein · Alzheimer disease · autosomal dominant inheritance · clinical trial · diagnostic accuracy · differential diagnosis · drug efficacy · early diagnosis · evidence based medicine · evidence based practice · gene expression profiling · gene locus · genetic analysis · genetic association · genetic counseling · genetic polymorphism · genetic risk · genetic screening · genetic variability · genomics · genotype · health care management · high risk patient · high risk population · human · incidence · medical research · pharmacogenomics · practice guideline · prediction · priority journal · review · treatment response
[Abstract]

20 Apolipoprotein C-I binds free fatty acids and reduces their intracellular esterification
article 2007    
Author: Westerterp, M. · Berbée, J.F.P. · Delsing, D.J.M. · Jong, M.C. · Gijbels, M.J.J. · Dahlmans, V.E.H. · Offerman, E.H. · Romijn, J.A. · Havekes, L.M. · Rensen, P.C.N.
Keywords: Biology · Biomedical Research · Lipoprotein · Lipoprotein lipase · Skin · Triglyceride · very low density lipoprotein · animal cell · animal experiment · animal tissue · controlled study · electricity · esterification · female · in vitro study · mouse · nonhuman · phenotype · skin transplantation · wild type · Animals · Apolipoprotein C-I · Cells, Cultured · Enzyme-Linked Immunosorbent Assay · Esterification · Fatty Acids, Nonesterified · Female · Humans · Lipoproteins, VLDL · Macrophages · Male · Mice · Mice, Inbred C57BL · Mice, Knockout · Mice, Transgenic · Oleic Acid · Phenotype · Protein Binding · Skin · Skin Abnormalities · Skin Transplantation
[PDF] [Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 36 found. Next | Sort by date