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1 Fibrinogen and atherosclerosis : A study in transgenic mice
article 1997    
Author: Koopman, J. · Maas, A. · Rezaee, F. · Havekes, L. · Verheijen, J. · Gijbels, M. · Haverkate, F.
Keywords: Biology · Animal experiment · Atherogenesis · Atherosclerosis · Atherosclerotic plaque · Conference paper · Fibrinogen blood level · Mouse · Nonhuman · Priority journal · Transgenic mouse
[Abstract]

2 Activation of the innate immune system in atherosclerotic disease
article 2007    
Author: Oude Nijhuis, M.M. · Keulen, J.K. van · Pasterkamp, G. · Quax, P.H. · Kleijn, D.P.V. de
Keywords: Biomedical Research · Atherogenesis · Infection · Inflammation · Innate immunity · Toll-like receptors · antibiotic agent · azithromycin · e 5331 · e 5531 · e 5564 · eritoran · ligand · lipid A derivative · lipopolysaccharide antagonist · low density lipoprotein · malonaldehyde · oxidized low density lipoprotein · placebo · receptor blocking agent · toll like receptor · vaccine · antigen recognition · atherogenesis · atherosclerosis · clinical trial · disease course · drug megadose · drug targeting · genetic polymorphism · human · innate immunity · knockout mouse · low drug dose · nonhuman · priority journal · review · signal transduction · vaccination · Animals · Atherosclerosis · Communicable Diseases · Humans · Immunity, Natural · Immunotherapy · Inflammation · Ligands · Lipopolysaccharides · Lipoproteins · Peptidoglycan · Signal Transduction · Toll-Like Receptors · Vaccines
[Abstract]

3 Autoantibodies against MDA-LDL in subjects with severe and minor atherosclerosis and healthy population controls
article 1996    
Author: Vijver, L.P.L. van de · Steyger, R. · Poppel, G. van · Boer, J.M.A. · Kruijssen, D.A.C.M. · Seidell, J.C. · Princen, H.M.G.
Keywords: Biology · Atherosclerosis · Autoantibodies · Cardiovascular diseases · LDL oxidation · cholesterol · low density lipoprotein · atherogenesis · atherosclerosis · controlled study · coronary artery disease · lipid oxidation · major clinical study · Adult · Aged · Autoantibodies · Body Mass Index · Case-Control Studies · Coronary Angiography · Coronary Arteriosclerosis · Enzyme-Linked Immunosorbent Assay · Female · Humans · Lipoproteins, LDL · Male · Malondialdehyde · Middle Aged · Oxidation-Reduction · Random Allocation · Regression Analysis · Risk Factors
[Abstract]

4 Omega-3 fatty acids in adipose tissue and risk of myocardial infarction: The EURAMIC study
article 1999    
Author: Guallar, E. · Aro, A. · Jiménez, F.J. · Martín-Moreno, J.M. · Salminen, I. · Veer, P. van 't · Kardinaal, A.F.M. · Gömez-Aracena, J. · Martin, B.C. · Kohlmeier, L. · Kark, J.D. · Mazaev, V.P. · Ringstad, J. · Guillén, J. · Riemersma, R.A. · Huttunen, J.K. · Thamm, M. · Kok, F.J.
Keywords: α-linolenic acid · Adipose tissue · Case- control studies · Docosahexaenoic acid · Myocardial infarction · docosahexaenoic acid · linoleic acid · omega 3 fatty acid · adipose tissue · antiarrhythmic activity · article · atherogenesis · capillary gas chromatography · case control study · cell membrane · cigarette smoking · Europe · fatty acid metabolism · heart infarction · human · Israel · major clinical study · priority journal · risk assessment · risk factor · thrombosis · Adipose Tissue · Aged · Case-Control Studies · Europe · Fatty Acids, Omega-3 · Humans · Male · Middle Aged · Myocardial Infarction · Random Allocation · Risk Factors
[Abstract]

5 Hepatic low-density lipoprotein receptor-related protein deficiency in mice increases atherosclerosis independent of plasma cholesterol
article 2004    
Author: Espirito Santo, S.M.S. · Pires, N.M.M. · Boesten, L.S.M. · Gerritsen, G. · Bovenschen, N. · Dijk, K.W. van · Jukema, J.W. · Princen, H.M.G. · Bensadoun, A. · Li, W.P. · Herz, J. · Havekes, L.M. · Vlijmen, B.J.M. van
Keywords: Blood clotting factor 8 · Cholesterol · Ligand · Lipoprotein lipase · Liver protein · Low density lipoprotein receptor · Low density lipoprotein receptor related protein · Tissue plasminogen activator · Triacylglycerol · Von Willebrand factor · Animal experiment · Animal model · Animal tissue · Atherogenesis · Cholesterol blood level · Controlled study · Hyperlipoproteinemia type 3 · Liver function · Liver metabolism · Mouse · Nonhuman · Protein deficiency · Triacylglycerol blood level · Animals · Aorta · Apolipoproteins E · Arteriosclerosis · Blood Coagulation Factors · Cholesterol · LDL-Receptor Related Protein 1 · Lipids · Liver · Male · Mice · Mice, Knockout · Mice, Transgenic · Receptors, LDL
[Abstract]

6 Seasonal variation in low density lipoprotein oxidation and antioxidant status
article 1997    
Author: Vijver, L.P.L. van de · Duyvenvoorde, W. van · Buytenhek, R. · Laarse, A. van der · Kardinaal, A.F.M. · Berg, H. van den · Princen, H.M.G.
Keywords: Antioxidants · LDL oxidation · Particle size · Within-subject seasonal variation · alpha tocopherol · antioxidant · beta carotene · cholesterol · copper ion · low density lipoprotein · xanthophyll · antioxidant activity · article · atherogenesis · cholesterol blood level · clinical article · controlled study · lipid blood level · lipid composition · lipid peroxidation · lipoprotein blood level · normal human · particle size · seasonal variation · vitamin blood level · Adult · Antioxidants · Cholesterol · Cholesterol, LDL · Fatty Acids · Female · Humans · Lipids · Lipoproteins, LDL · Lutein · Male · Middle Aged · Oxidation-Reduction · Seasons · Vitamin E

7 Induction of atherosclerotic plaque rupture in apolipoprotein E-/- mice after adenovirus-mediated transfer of p53
article 2002    
Author: Thüsen, J.H. von der · Vlijmen, B.J.M. van · Hoeben, R.C. · Kockx, M.M. · Havekes, L.M. · Berkel, T.J.C. van · Biessen, E.A.L.
Keywords: Health · Carotid arteries · Genes · Muscle · Adenovirus vector · Apolipoprotein E · Beta galactosidase · Phenylephrine · Protein p53 · Animal experiment · Animal model · Atherogenesis · Atherosclerotic plaque · Carotid artery · Cell death · Controlled study · Gene overexpression · Genetic transfection · Knockout mouse · Mouse · Nonhuman · Rupture · Smooth muscle fiber · Thrombosis · Transgene · Tumor suppressor gene · Adenoviridae · Animals · Apolipoproteins E · Apoptosis · Arteriosclerosis · beta-Galactosidase · Biological Markers · Carotid Artery Diseases · Cell Division · Genetic Vectors · Immunohistochemistry · Mice · Mice, Knockout · Muscle, Smooth, Vascular · Transfection · Tumor Suppressor Protein p53
[Abstract]

8 Sex steroids and lipoprotein metabolism
article 1994    
Author: Gevers Leuven, J.A.
Keywords: Health · Cardiovascular risk · Cholesterol · Estrogens · Lipoproteins · Progestogens · Sex steroids · chlormadinone acetate · cholesterol · conjugated estrogen · cyproterone acetate · desogestrel · dydrogesterone · gestodene · high density lipoprotein · hydroxytamoxifen · low density lipoprotein · lynestrenol · medrogestone · medroxyprogesterone acetate · mifepristone · norethisterone · noretynodrel · norgestimate · norgestrel · oral contraceptive agent · sex hormone · steroid receptor · very low density lipoprotein · atherogenesis · cardiovascular disease · drug structure · lipid metabolism · lipoprotein metabolism · Animal · Arteriosclerosis · Cardiovascular Diseases · Contraceptives, Oral, Hormonal · Female · Human · Lipoproteins · Male · Risk Factors · Sex Hormones
[Abstract]

9 Cytokines and atherosclerosis: A comprehensive review of studies in mice
article 2008    
Author: Kleemann, R. · Zadelaar, A.S.M. · Kooistra, T.
Keywords: Health · Atherosclerosis · Cytokines · Macrophage · Gamma interferon · Granulocyte colony stimulating factor · Granulocyte macrophage colony stimulating factor · Interleukin 1 · Interleukin 10 · Interleukin 12 · Interleukin 18 · Interleukin 2 · Interleukin 20 · Interleukin 3 · Interleukin 4 · Interleukin 5 · Interleukin 6 · Atherogenesis · Diet · Gene deletion · Gene overexpression · Mouse strain · Nonhuman · Outcome assessment · Protein expression · Review · Sex difference · Animals · Atherosclerosis · Colony-Stimulating Factors · Cytokines · Disease Models, Animal · Inflammation · Interferon-gamma · Interleukins · Macrophage Migration-Inhibitory Factors · Mice · Signal Transduction · Tumor Necrosis Factor-alpha
[Abstract]

10 Apolipoprotein C-I is crucially involved in lipopolysaccharide-induced atherosclerosis development in apolipoprotein E-knockout mice
article 2007    
Author: Westerterp, M. · Berbée, J.F.P. · Pires, N.M.M. · Mierlo, G.J.D. van · Kleemann, R. · Romijn, J.A. · Havekes, L.M. · Rensen, P.C.N.
Keywords: Biomedical Research · Apolipoproteins · Atherosclerosis · Hypercholesterolemia · Inflammation · Leukocytes · Lipoproteins · apolipoprotein C1 · apolipoprotein E · bacterium lipopolysaccharide · endothelial leukocyte adhesion molecule 1 · fibrinogen · tumor necrosis factor alpha · animal cell · animal experiment · animal model · animal tissue · aorta atherosclerosis · aorta root · article · atherogenesis · atherosclerosis · bacterial infection · controlled study · female · fibrinogen blood level · inflammation · knockout mouse · macrophage · mouse · nonhuman · priority journal · protein blood level · protein expression · Animals · Apolipoproteins C · Atherosclerosis · Biological Markers · Cells, Cultured · Cholesterol, HDL · E-Selectin · Female · Fibrinogen · Hypercholesterolemia · Lipopolysaccharides · Macrophages, Peritoneal · Male · Mice · Mice, Inbred C57BL · Mice, Mutant Strains · Monocytes · T-Lymphocytes · Tumor Necrosis Factor-alpha · Vasculitis
[ABSTRACT] [Abstract]

11 Macrophage specific overexpression of the human macrophage scavenger receptor in transgenic mice, using a 180-kb yeast artificial chromosome, leads to enhanced foam cell formation of isolated peritoneal macrophages
article 1999    
Author: Winther, M.P.J. de · Dijk, K.W. van · Vlijmen, B.J.M. van · Gijbels, M.J.J. · Heus, J.J. · Wijers, E.R. · Bos, A.C. van den · Breuer, M. · Frants, R.R. · Havekes, L.M. · Hofker, M.H.
Keywords: Biology · Acetyl-low density lipoprotein · Macrophage scavenger receptor · Transgenics · Yeast artificial chromosome · acetyl low density lipoprotein · cholesterol ester · scavenger receptor · animal cell · animal experiment · article · atherogenesis · cell proliferation · controlled study · foam cell · gene overexpression · immunohistochemistry · mouse · nonhuman · peritoneum macrophage · priority journal · transgenic mouse · yeast artificial chromosome · Animals · Base Sequence · Cells, Cultured · Chromosomes, Artificial, Yeast · Disease Models, Animal · Foam Cells · Gene Expression · Humans · Kupffer Cells · Lipoproteins, LDL · Macrophages, Peritoneal · Mice · Mice, Transgenic · Molecular Sequence Data · Polymerase Chain Reaction · Receptors, Immunologic · Receptors, Scavenger · RNA, Messenger · Scavenger Receptors, Class A · Sensitivity and Specificity · Species Specificity · Tissue Distribution
[Abstract]

12 Macrophage low-density lipoprotein receptor-related protein deficiency enhances atherosclerosis in apoE/LDLR double knockout mice
article 2006    
Author: Hu, L. · Boesten, L.S.M. · May, P. · Herz, J. · Bovenschen, N. · Huisman, M.V. · Berbée, J.F.P. · Havekes, L.M. · Vlijmen, B.J.M. van · Tamsma, J.T.
Keywords: Biology · Biomedical Research · Atherosclerosis · Genetically altered mice · LRP · Macrophage · Spolipoprotein E · CD3 antigen · Aholesterol · Lipoprotein · Low density lipoprotein receptor · Triacylglycerol · Animal cell · Animal model · Animal tissue · Aorta root · Atherogenesis · Cell count · Cholesterol blood level · Control group · Controlled study · Gene deletion · In vivo study · Knockout mouse · Male · Monocyte · Mouse · Nonhuman · Observation · Protein deficiency · Protein localization · Protein transport · Smooth muscle fiber · T lymphocyte · Triacylglycerol blood level · Animals · Apolipoproteins E · Collagen · Female · Gene Expression Regulation · LDL-Receptor Related Protein 1 · Lipoproteins · Macrophages · Mice · Mice, Knockout · Receptors, LDL
[Abstract]

13 No effect of C-reactive protein on early atherosclerosis development in apolipoprotein E*3-Leiden/human C-reactive protein transgenic mice
article 2005    
Author: Trion, A. · Maat, M.P.M. de · Jukema, J.W. · Laarse, A. van der · Maas, M.C. · Offerman, E.H. · Havekes, L.M. · Szalai, A.J. · Princen, H.M.G. · Emeis, J.J.
Keywords: Biology · Biomedical Research · Atherosclerosis · C-reactive protein · Inflammation · Mouse · Transgene · Acute phase protein · Apolipoprotein E3 Leiden · Biological marker · C reactive protein · Cholesterol · Unclassified drug · Animal experiment · Animal model · Animal tissue · Atherogenesis · Blood sampling · Cardiovascular risk · Cholesterol blood level · Cholesterol diet · Controlled study · Enzyme linked immunosorbent assay · Experimental model · Histopathology · Hypercholesterolemia · Immunohistochemistry · Inflammation · Mouse strain · Nonhuman · Pathophysiology · Protein blood level · Protein expression · Protein function · Transgenic mouse · Animals · Apolipoprotein E3 · Apolipoproteins E · Atherosclerosis · Biological Markers · Body Weight · C-Reactive Protein · Cholesterol · Early Diagnosis · Eating · Endothelium, Vascular · Female · Humans · Hypercholesterolemia · Male · Mice · Mice, Transgenic · Monocytes · Risk Factors · Severity of Illness Index
[Abstract]

14 Fenofibrate reduces atherogenesis in ApoE*3Leiden mice: Evidence for multiple antiatherogenic effects besides lowering plasma cholesterol
article 2006    
Author: Kooistra, T. · Verschuren, L. · Vries de-Weij, J.van der · Koenig, W. · Toet, K. · Princen, H.M.G. · Kleemann, R.
Keywords: Biology · Biomedical Research · Atherosclerosis · Fibrates · Inflammation · Pleiotrop · Reverse cholesterol transport · ABC transporter A1 · Cholesterol · Fenofibrate · Granulocyte macrophage colony stimulating factor · Immunoglobulin enhancer binding protein · Intercellular adhesion molecule 1 · Monocyte chemotactic protein 1 · Serum amyloid A · Vascular cell adhesion molecule 1 · Animal cell · Animal experiment · Animal model · Animal tissue · Aorta atherosclerosis · Atherogenesis · Cholesterol blood level · Cholesterol diet · Cholesterol transport · Controlled study · Disease severity · Drug effect · Macrophage · Mouse · Nonhuman · Protein blood level · Protein expression · Transgenic mouse · Upregulation · Animals · Antilipemic Agents · Aorta · Aortic Valve · Apolipoprotein E3 · Apolipoproteins E · Atherosclerosis · Cholesterol · Female · Inflammation · Lipids · Lipoproteins · Mice · Mice, Transgenic · Procetofen
[Abstract]

15 Evidence for anti-inflammatory activity of statins and PPARα activators in human C-reactive protein transgenic mice in vivo and in cultured human hepatocytes in vitro
article 2004    
Author: Kleemann, R. · Verschuren, L. · Rooij, B.J. de · Lindeman, J. · Maat, M.M.de · Szalai, A.J. · Princen, H.M.G. · Kooistra, T.
Keywords: Biomedical Research · Antilipemic agent · C reactive protein · CCAAT enhancer binding protein · Cholesterol · Fenofibrate · Hydroxymethylglutaryl coenzyme A reductase inhibitor · I kappa B alpha · Immunoglobulin enhancer binding protein · Interleukin 1beta · Peroxisome proliferator activated receptor agonist · Peroxisome proliferator activated receptor alpha · Peroxisome proliferator activated receptor alpha agonist · Pirinixic acid · Protein p50 · Unclassified drug · Animal experiment · Animal model · Animal tissue · Antiinflammatory activity · Atherogenesis · Atherosclerosis · Cardiovascular risk · Cell culture · Cholesterol blood level · Controlled study · Hepatoma cell · Human cell · Inflammation · Liver cell · Mouse · Nonhuman · Transgenic mouse · Animals · C-Reactive Protein · Carcinoma, Hepatocellular · CCAAT-Enhancer-Binding Proteins · Cell Line, Tumor · Cholesterol · Down-Regulation · Gene Expression · Hepatocytes · Heptanoic Acids · Humans · Hydroxymethylglutaryl-CoA Reductase Inhibitors · I-kappa B Proteins · Interleukin-1 · Male · Mice · Mice, Transgenic · NF-kappa B · NF-kappa B p50 Subunit · Pyrroles · Receptors, Cytoplasmic and Nuclear · Simvastatin · Transcription Factors · Up-Regulation
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 15 of 15 found. | Sort by date