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1 Bioaccessibility of Folic Acid and (6S)-5-Methyltetrahydrofolate Decreases after the Addition of Folate-Binding Protein to Yogurt as Studied in a Dynamic in Vitro Gastrointestinal Model
article 2003    
Author: Arkbåge, K. · Verwei, M. · Havenaar, R. · Witthöft, C.
Keywords: Health · Physiological Sciences · Folate bioaccessibility · Folate-binding protein · In vitro gastrointestinal model · Pasteurized milk · Yogurt · 5 methyltetrahydrofolic acid · folate binding protein · folic acid · yoghurt · article · bioavailability · food composition · food processing · milk · pasteurization · protein binding · Animals · Biological Availability · Carrier Proteins · Digestive Physiology · Digestive System · Folic Acid · Intestinal Mucosa · Jejunum · Milk · Models, Biological · Receptors, Cell Surface · Tetrahydrofolates · Yogurt
[Abstract]

2 Folic acid and 5-methyltetrahydrofolate in fortified milk are bioaccessible as determined in a dynamic in vitro gastrointestinal model
article 2003    
Author: Verwei, M. · Arkbåge, K. · Havenaar, R. · Berg, H. van den · Witthöft, C. · Schaafsma, G.
Keywords: Nutrition · Physiological Sciences · Bioavailability · Folate · Folate-binding protein · Fortified milk · In vitro gastrointestinal model · 5 methyltetrahydrofolic acid · folate binding protein · folic acid · article · bioavailability · compartment model · computer model · high temperature · intermethod comparison · milk · milk level · protein stability · stomach absorption · stomach pH · Animals · Biological Availability · Chromatography, High Pressure Liquid · Digestive System · Folic Acid · Food, Fortified · Milk · Models, Biological · Tetrahydrofolates
[Abstract]

3 Detection of GTP-binding proteins in barley aleurone protoplasts
article 1993    
Author: Wang, M. · Sedee, N.J.A. · Heidekamp, F. · Snaar-Jagalska, B.E.
Keywords: Barley aleurone · GTP-binding protein · Phytohormone · Guanine nucleotide binding protein · Phytohormone · Barley · Nonhuman · Protein purification · Protoplast · Binding Sites · Blotting, Western · Cell Membrane · Electrophoresis, Polyacrylamide Gel · GTP-Binding Proteins · Hordeum · Plant Growth Regulators · Protoplasts · Signal Transduction · Support, Non-U.S. Gov't · Temperature
[PDF] [Abstract]

4 Transient and prolonged increase in endothelial permeability induced by histamine and thrombin : Role of protein kinases, calcium, and RhoA
article 1998    
Author: Nieuw Amerongen, G.P. van · Draijer, R. · Vermeer, M.A. · Hinsbergh, V.W.M. van
Keywords: Biology · Human endothelial cell · Protein kinase C · Protein tyrosine kinase · RhoA · Calcium · Capillary Permeability · Cells, Cultured · Cytoskeleton · Endothelium, Vascular · GTP-Binding Proteins · Histamine · Humans · Infant, Newborn · Protein Kinases · Protein-Tyrosine Kinases · rhoA GTP-Binding Protein · Thrombin · Time Factors
[Abstract]

5 Global Suppression of IL-6-induced Acute Phase Response Gene Expression after Chronic in Vivo Treatment with the Peroxisome Proliferator-activated Receptor-α Activator Fenofibrate
article 2004    
Author: Gervois, P. · Kleemann, R. · Pilon, A. · Percevault, F. · Koenig, W. · Staels, B. · Kooistra, T.
Keywords: Biology · Biomedical Research · Biological organs · Enzyme kinetics · Lipids · Metabolism · Patient treatment · Plasmas · Acute phase response (APR) · Gene expression · Genetic engineering · Albumin · Alpha 2 macroglobulin · CCAAT enhancer binding protein · CCAAT enhancer binding protein alpha · CCAAT enhancer binding protein beta · CCAAT enhancer binding protein delta · Fenofibrate · Fibrinogen · Interleukin 6 · peroxisome proliferator activated receptor agonist · peroxisome proliferator activated receptor alpha · serum amyloid A · STAT3 protein · Stress activated protein kinase · Transcription factor · Unclassified drug · Acute phase response · Animal experiment · Animal tissue · Clinical article · Controlled study · Down regulation · Enzyme activation · Fibrinogen blood level · Gene expression regulation · Hyperlipidemia · In vivo study · Knockout mouse · Liver · Long term care · Male · Mouse · Nonhuman · Protein expression · Protein function · Protein phosphorylation · Transcription regulation · Wild type · Acute-Phase Reaction · Animals · Antilipemic Agents · Apolipoproteins · Down-Regulation · Fibrinogen · Haptoglobins · Humans · Interleukin-6 · Mice · Procetofen · Receptors, Cytoplasmic and Nuclear · Serum Amyloid A Protein · Signal Transduction · Transcription Factors · Animalia · Eukaryota
[PDF] [Abstract]

6 Effect of folate-binding protein on intestinal transport of folic acid and 5-methyltetrahydrofolate across Caco-2 cells
article 2005    
Author: Verwei, M. · Berg, H. van den · Havenaar, R. · Groten, J.P.
Keywords: Biology · Biomedical Research · Bioavailability · Caco-2 · Folate · Folate-binding protein · Intestinal transport · 5 methyltetrahydrofolic acid · caffeine · folate binding protein · folic acid · mannitol · article · cell growth · cell membrane permeability · controlled study · human · human cell · intestine absorption · intestine cell · monolayer culture · protein binding · Biological Transport · Caco-2 Cells · Carrier Proteins · Cell Culture Techniques · Chromatography, Gel · Folic Acid · Humans · Intestinal Absorption · Intestine, Small · Receptors, Cell Surface · Tetrahydrofolates · Time Factors · Bovinae
[Abstract]

7 The Binding of Folic Acid and 5-Methyltetrahydrofolate to Folate-Binding Proteins during Gastric Passage Differs in a Dynamic in Vitro Gastrointestinal Model
article 2004    
Author: Verwei, M. · Arkbåge, K. · Mocking, H. · Havenaar, R. · Groten, J.
Keywords: Biology · Physiological Sciences · 5-Methyltetrahydrofolate · Folate-binding protein · Folic acid · Gastric passage · Milk products · 5 methyltetrahydrofolic acid · folate binding protein · folic acid · absorption · article · dairy product · duodenum · dynamics · food intake · gastrointestinal tract · in vitro study · milk level · model · nonhuman · protein binding · simulation · vitamin supplementation · Animals · Carrier Proteins · Chromatography, Gel · Duodenum · Folic Acid · Food, Fortified · Gastrointestinal Transit · Humans · Milk · Milk Proteins · Models, Biological · Protein Binding · Receptors, Cell Surface · Tetrahydrofolates
[Abstract]

8 Nur77 modulates hepatic lipid metabolism through suppression of SREBP1c activity
article 2008    
Author: Pols, T.W.H. · Ottenhoff, R. · Vos, M. · Levels, J.H.M. · Quax, P.H.A. · Meijers, J.C.M. · Pannekoek, H. · Groen, A.K. · Vries, C.J.M. de
Keywords: Biology · Lipid metabolism · NR4A nuclear receptors · NR4A1 · Nur77 · SREBP1c · Sterol regulatory element binding protein-1 · ABC transporter · ABC transporter G5 · ABC transporter G8 · acyl coenzyme A desaturase · acyl coenzyme A desaturase 1 · adenovirus vector · fatty acid synthase · glycerol 3 phosphate acyltransferase · low density lipoprotein receptor · nuclear receptor Nur77 · sterol regulatory element binding protein 1c · triacylglycerol · animal experiment · animal tissue · article · controlled study · enzyme activity · enzyme repression · gene expression · genetic analysis · lipid blood level · lipid liver level · lipid metabolism · male · mouse · nonhuman · nucleotide sequence · priority journal · protein expression · protein function · Adenoviridae · Animals · DNA-Binding Proteins · Gene Expression Regulation · Lipid Metabolism · Liver · Male · Mice · Mice, Inbred C57BL · Receptors, Cytoplasmic and Nuclear · Receptors, Steroid · RNA, Messenger · Sterol Regulatory Element Binding Protein 1 · Transcription Factors · Triglycerides · Mus
[Abstract]

9 Are zebrafish larvae suitable for assessing the hepatotoxicity potential of drug candidates?
article 2015    
Author: Mesens, N. · Crawfordb, A.D. · Menke, A. · Hung, P.D. · Goethem, F. van · Nuyts, R. · Hansen, E. · Wolterbeek, A. · Gompel, J. van · Witte, P. de · Esguerra, C.V.
Keywords: Nutrition · Zebrafish larvae · Screening assay · Lfabp10a · Hepatotoxicity · DILI · Alpidem · Amiodarone · Bosentan · Buspirone · Diclofenac · Fatty acid binding protein · Fatty acid binding protein 10a · Glycogen · Ketorolac · Nefazodone · Paracetamol · Reactive oxygen metabolite · Rosiglitazone · Tacrine · Tamoxifen · Tetracycline · Troglitazone · Unclassified drug · Zolpidem · Adult · Animal tissue · Cell vacuole · Cholestasis · Circulation · Concentration response · Controlled study · Drug safety · Female · Glycogen analysis · Heart rate · Histology · Histopathology · In situ hybridization · Larval stage · Liver cell · Liver level · Liver size · Liver toxicity · Male · Mitochondrial membrane · Mitochondrial toxicity · Molecular cloning · Nonhuman · Protein expression · Steatosis · Toxicity testing · Zebra fish · Danio rerio · Food and Nutrition · Healthy Living · Life · RAPID - Risk Analysis for Products in Development · ELSS - Earth, Life and Social Sciences
[Abstract]

10 Anacetrapib reduces (V)LDL-cholesterol by inhibition of CETP activity and reduction of plasma PCSK9
article 2015    
Author: Tuin, S.J. van der · Kühnast, S. · Berbée, J. · Verschuren, L. · Pieterman, E.J. · Havekes, L.M. · Hoorn, J.W. van der · Rensen, P.C. · Jukema, J.W. · Princen, H.M. · Willems van Dijk, K. · Wang, Y.
Keywords: Health · CETP · Cholesterol · Metabolism · Drug therapy · Hypolipidemic drugs · LDL · Metabolism · Lipids · Lipoproteins · PCSK9 · Anacetrapib · Apolipoprotein B · Cholesterol ester transfer protein · Low density lipoprotein receptor · Proprotein convertase subtilisin kexin type 9 · RNA · Serine proteinase · Sterol regulatory element binding protein 1 · Sterol regulatory element binding protein 2 · Triacylglycerol · Unclassified drug · Very low density lipoprotein cholesterol · Animal experiment · Animal tissue · Atherosclerosis · Cholesterol synthesis · Controlled study · Down regulation · Drug mechanism · Enzyme blood level · Female · Liver · Microarray analysis · Mouse · Nonhuman · Polymerase chain reaction · Protein expression · RNA isolation · Western diet · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research MSB - Microbiology and Systems Biology · ELSS - Earth, Life and Social Sciences
[PDF] [Abstract]

11 Apolipoprotein CI enhances the biological response to LPS via the CD14/TLR4 pathway by LPS-binding elements in both its N- and C-terminal helix
article 2010    
Author: Berbé, J.F.P. · Coomans, C.P. · Westerterp, M. · Romijn, J.A. · Havekes, L.M. · Rensen, P.C.N.
Keywords: Biology · Biomedical Research · Endotoxins · Inflammation · Mice · Peptide · Tnfα · Apolipoprotein C1 · CD14 antigen · Lipopolysaccharide · Lipopolysaccharide binding protein · Toll like receptor 4 · Tumor necrosis factor alpha · Amino terminal sequence · Animal cell · Animal experiment · Carboxy terminal sequence · Controlled study · Cytokine release · Electrophoretic mobility · Mouse · Nonhuman · Peritoneum macrophage · Plasma clearance · Signal transduction
[PDF] [Abstract]

12 Review article: the role of butyrate on colonic function
article 2008    
Author: Hamer, H.M. · Jonkers, D. · Venema, K. · Vanhoutvin, S. · Troost, F.J. · Brummer, R.J.
Keywords: Nutrition Biology · Biomedical Research · Butyric acid · Corticosteroid · Enema · Histone deacetylase inhibitor · Immunoglobulin enhancer binding protein · Inulin · Ispagula · Mesalazine · Short chain fatty acid · Carcinogenesis · Colitis · Colon carcinogenesis · Colon mucosa · Combination chemotherapy · Deacetylation · Intestine mucosa permeability · Monotherapy · Proctitis · Satiety · Ulcerative colitis · Butyrates · Carbohydrate Metabolism · Colonic Neoplasms · Dietary Fiber · Fatty Acids, Volatile · Inflammation · Intestinal Mucosa · Oxidative Stress · Satiation
[Abstract]

13 Calnexin overexpression increases manganese peroxidase production in Aspergillus niger
article 2002    
Author: Conesa, A. · Jeenes, D. · Archer, D.B. · Hondel, C.A.M.J.J. van den · Punt, P.J.
Keywords: Biology · Biotechnology · Biosynthesis · Fungi · Genes · Manganese · Proteins · Binding protein · Microbiology · Calnexin · Fungal protein · Manganese peroxidase · Peroxidase · Aspergillus niger · Basidiomycetes · Bipa gene · Clxa gene · Controlled study · gene overexpression · Phanerochaete · Protein analysis · Protein expression · Aspergillus niger · Calcium-Binding Proteins · Calnexin · Culture Media · Fungal Proteins · Heme · HSP70 Heat-Shock Proteins · Peroxidases · Phanerochaete · Transformation, Genetic · Aspergillus · Aspergillus niger · Basidiomycota · Chrysosporium · Phanerochaete · Phanerochaete chrysosporium
[PDF] [Abstract]

14 Hexachlorobenzene and its metabolites pentachlorophenol and tetrachlorohydroquinone: Interacion with thyroxine binding sites of rat thyroid hormone carriers ex vivo and in vitro
article 1991    
Author: Raaij, J.A.G.M. van · Berg, K.J. van den · Notten, W.R.F.
Keywords: Biology · Binding sites · Carrier · Hexachlorobenzene · Occupation · Pentachlorophenol · Tetrachlorohydroquinone · Th yroxine · Hexachlorobenzene · Pentachlorophenol · Tetrachlorohydroquinone · Thyroxine · Thyroxine binding protein · Animal experiment · Animal tissue · Hypothyroidism · Metabolite · Nonhuman · Priority journal · Rat · Animal · Binding Sites · Binding, Competitive · Hexachlorobenzene · Hydroquinones · Hypothyroidism · Injections, Intraperitoneal · Pentachlorophenol · Rats · Support, Non-U.S. Gov't · Thyroxine
[Abstract]

15 Expression of cbsA encoding the collagen-binding S-protein of Lactobacillus crispatus JCM5810 in Lactobacillus casei ATCC 393T
article 2000    
Author: Martínez, B. · Sillanpää, J. · Smit, E. · Korhonen, T.K. · Pouwels, P.H.
Keywords: Nutrition · Bacterial protein · Binding protein · Collagen binding s protein · Unclassified drug · Bacterium adherence · Gene expression · Lactobacillus · Lactobacillus casei · Lactobacillus crispatus · Nonhuman · Priority journal · Protein secretion · Signal transduction · Bacterial Proteins · Cell Membrane · Integrins · Lactobacillus · Lactobacillus casei · Membrane Glycoproteins · Membrane Proteins · Receptors, Collagen · Bacteria (microorganisms) · Lactobacillus casei · Lactobacillus crispatus · Posibacteria
[Abstract]

16 Role of RhoA and Rho kinase in lysophosphatidic acid-induced endothelial barrier dysfunction.
article 2000    
Author: Nieuw Amerongen, G.P. van · Vermeer, M.A. · Hinsbergh, V.W. van
Keywords: Biology · Amides · Calcium · Cell Membrane Permeability · Cells, Cultured · Cyclic AMP · Cytoskeleton · Dose-Response Relationship, Drug · Endothelium, Vascular · Enzyme Activation · Enzyme Inhibitors · Horseradish Peroxidase · Humans · Intracellular Signaling Peptides and Proteins · Myosin Light Chains · Phosphatidic Acids · Phosphorylation · Protein-Serine-Threonine Kinases · Pyridines · rhoA GTP-Binding Protein · Thrombin · Time Factors · Umbilical Veins
[Abstract]

17 Fibrates down-regulate IL-1-stimulated C-reactive protein gene expression in hepatocytes by reducing nuclear p50-NFκB-C/EBP-β complex formation
article 2003    
Author: Kleemann, R. · Gervois, P.P. · Verschuren, L. · Staels, B. · Princen, H.M.G. · Kooistra, T.
Keywords: Biology · Animals · Antilipemic Agents · Bezafibrate · C-Reactive Protein · CCAAT-Enhancer-Binding Protein-beta · Cell Nucleus · Clofibric Acid · Down-Regulation · Hepatocytes · Humans · Interleukin-1 · Mice · Mice, Knockout · NF-kappa B · NF-kappa B p50 Subunit · Protein Binding · Receptors, Cytoplasmic and Nuclear · Transcription Factors · Transcription, Genetic · Transfection
[Abstract]

18 Negative Regulation of Human Fibrinogen Gene Expression by Peroxisome Proliferator-activated Receptor α Agonists via Inhibition of CCAAT Box/Enhancer-binding Protein β
article 2001    
Author: Gervois, P. · Vu-Dac, N. · Kleemann, R. · Kockx, M. · Dubois, G. · Laine, B. · Kosykh, V. · Fruchart, J.C. · Kooistra, T. · Staels, B.
Keywords: Western blotting · Blotting, Northern · Blotting, Western · CCAAT-Enhancer-Binding Protein-alpha · Cell Line · Dose-Response Relationship, Drug · Down-Regulation · Fibrinogen · Hepatocytes · Humans · Inflammation · Interleukin-6 · Liver · Mutagenesis, Site-Directed · Nuclear Receptor Coactivator 2 · Peroxisome Proliferators · Plasmids · Precipitin Tests · Promoter Regions (Genetics) · Pyrimidines · Receptors, Cytoplasmic and Nuclear · Transcription Factors · Transcription, Genetic · Transfection · Tumor Cells, Cultured
[PDF] [Abstract]

19 Involvement of RhoA/Rho kinase signaling in VEGF-induced endothelial cell migration and angiogenesis in vitro
article 2003    
Author: Nieuw Amerongen, G.P. van · Koolwijk, P. · Versteilen, A. · Hinsbergh, V.W.M. van
Keywords: Amides · Capillaries · Cell Culture Techniques · Cell Movement · Cells, Cultured · Cytoskeleton · Endothelial Growth Factors · Endothelium, Vascular · Enzyme Activation · Enzyme Inhibitors · Fibrin · Humans · Intercellular Signaling Peptides and Proteins · Lymphokines · Male · Neovascularization, Physiologic · Penis · Pyridines · rho GTP-Binding Proteins · rhoA GTP-Binding Protein · Signal Transduction · Umbilical Veins · Vascular Endothelial Growth Factor A · Vascular Endothelial Growth Factors
[Abstract]

20 Activation of rhoa by thrombin in endothelial hyperpermeability: Role of rho kinase and protein tyrosine kinases
article 2000    
Author: Nieuw Amerongen, G.P. van · Delft, S.V. · Vermeer, M.A. · Collard, J.G. · Hinsbergh, V.W.M. van
Keywords: Amides · Calcium · Cell Membrane Permeability · Cells, Cultured · Cytoskeleton · Endothelium, Vascular · Enzyme Activation · Enzyme Inhibitors · Hemostatics · Humans · Intracellular Signaling Peptides and Proteins · Myosin Light Chains · Phosphorylation · Protein Binding · Protein-Serine-Threonine Kinases · Protein-Tyrosine Kinases · Proto-Oncogene Proteins c-akt · Pyridines · rhoA GTP-Binding Protein · Thrombin · Umbilical Veins
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 59 found. Next | Sort by date