Repository hosted by TU Delft Library

Home · Contact · About · Disclaimer ·
 

Search results also available in MS Excel format.

Showing 1 to 20 of 21 found. Next | Sort by date

1 International commission for protection against environmental mutagens and carcinogens (ICPEMC)
article 1981    
Author: Lohman, P.H.M.
Keywords: Biology · Carcinogen · Mutagenic agent · Heredity · Human · Legal aspect

2 International commission for protection against environmental mutagens and carcinogens
article 1980    
Author: Lohman, P.H.M.
Keywords: Biology · Carcinogen · Mutagenic agent · Protective agent · Environment · Carcinogens, Environmental · Human · International Agencies · Mutagens · Neoplasms
[Abstract]

3 The long-term study in rodents for identifying carcinogens: Some controversies and suggestions for improvements
article 1986    
Author: Feron, V.J. · Kroes, R.
Keywords: Animal experiment · Carcinogen testing · Chemical carcinogenesis · Intoxication · Mouse · Nonhuman · Rat · Rodent · Toxicity testing · Animal · Drug Administration Schedule · International Cooperation · Mutagenicity Tests · Rodentia · Zoology · Medicine · Geneeskunde · Pathology
[Abstract]

4 Long- and medium-term carcinogenicity studies in animals and short-term genotoxicity tests.
article 1999    
Author: Feron, V.J. · Schwarz, M. · Hemminki, K. · Krewski, D.
Keywords: Toxicology · biological marker · mutagenic agent · animal · bioassay · carcinogen testing · human · methodology · mouse · review · species difference · time · transgenic mouse · Animals · Biological Assay · Biological Markers · Carcinogenicity Tests · Humans · Mice · Mice, Transgenic · Mutagens · Research Design · Species Specificity · Time Factors

5 Short-term tests in the framework of carcinogen risk assessment to man
article 1983    
Author: Kroes, R.
Keywords: Carcinogen · Mutagenic agent · Chemical carcinogenesis · Etiology · Human · Methodology · Netherlands · Nonhuman · Risk · Short survey · Animal · Article · Bioassay · Biological model · Drug screening · Mutagen testing · Species difference · Animal · Biological Assay · Carcinogens · Drug Evaluation, Preclinical · Models, Biological · Mutagenicity Tests · Mutagens · Risk · Species Specificity
[Abstract]

6 Genotoxicity and mutagenicity
article 2005    
Author: Maurici, D. · Aardema, M. · Corvi, R. · Kleber, M. · Krul, C.A.M. · Laurent, C. · Loprieno, N. · Pasanen, M. · Pfuhler, S. · Phillips, B. · Sabbioni, E. · Sanner, T. · Vanparys, P.
Keywords: Toxicology · Physiological sciences · Animal testing replacement · Animal testing alternatives · Chromosome aberration · Comet assay · DNA damage · DNA synthesis · Gene mutation · Genotoxicity · In vitro study · In vivo study · Micronucleus test · Mitotic recombination · Mutagenicity · Sister chromatid exchange · Toxicity testing · Toxicogenetics · Toxicokinetics · Toxicological parameters · Carcinogen testing · Cell culture · Chemistry · Legal aspects · Structure activity relation · Animalia · Consumer product safety · Cosmetics · European Union · Structure-Activity Relationship

7 Induction of hyperplasia in the bladder epithelium of rats by a dietary excess of acid or base: Implications for toxicity/carcinogenicity testing
article 1988    
Author: Groot, A.P. de · Feron, V.J. · Immel, H.R.
Keywords: acid · alkali · ammonium chloride · glutamate sodium · potassium bicarbonate · acid base balance · animal experiment · bladder epithelium · bladder hyperplasia · carcinogen testing · diet · male · nonhuman · rat · toxicity testing · urine ph · Acid-Base Equilibrium · Ammonium Chloride · Animal · Bladder · Carbonates · Circadian Rhythm · Diet · Epithelium · Hydrogen-Ion Concentration · Hyperplasia · Male · Mutagenicity Tests · Potassium · Rats · Urine
[Abstract]

8 The carcinoGENOMICS project: Critical selection of model compounds for the development of omics-based in vitro carcinogenicity screening assays
article 2008    
Author: Vinken, M. · Doktorova, T. · Ellinger-Ziegelbauer, H. · Ahr, H.-J. · Lock, E. · Carmichael, P. · Roggen, E. · Delft, J. van · Kleinjans, J. · Castell, J. · Bort, R. · Donato, T. · Ryan, M. · Corvi, R. · Keun, H. · Ebbels, T. · Athersuch, T. · Sansone, S.-A. · Rocca-Serra, P. · Stierum, R. · Jennings, P. · Pfaller, W. · Gmuender, H. · Vanhaecke, T. · Rogiers, V.
Keywords: Biology · Physiological Sciences · carcinoGENOMICS · Chemical carcinogenesis · FP6 project · Genomics · Genotoxic carcinogen · Metabolomics · Metabonomics · Model compounds · Non-genotoxic carcinogen · REACH · Selection criteria · 1,3 butadiene · 2 nitrofluorene · 2,3,7,8 tetrachlorodibenzo para dioxin · aflatoxin B1 · alkanone · arsenate sodium · asbestos · benzo[a]pyrene · bromodichloromethane · cadmium derivative · chemical compound · chloroprene · chlorothalonil · dichromate sodium · dimethylnitrosamine · isobutyl nitrite · methapyrilene · monuron · nifedipine · ochratoxin · phenobarbital · phorbol 13 acetate 12 myristate · piperonyl butoxide · pirinixic acid · potassium bromate · s (1,2 dichlorovinyl)cysteine · streptozocin · tolbutamide · unindexed drug · vinyl chloride · carcinogenicity · genomics · human · in vitro study · medical information · medical research · model · nonhuman · priority journal · review · screening · Animal Testing Alternatives · Carcinogenicity Tests · European Union · Gene Expression Profiling · Genomics · Hazardous Substances · International Cooperation · Toxicogenetics · Animalia
[Abstract]

9 Meat and fat intake and pancreatic cancer risk in the Netherlands Cohort Study
article 2009    
Author: Heinen, M.M. · Verhage, B.A.J. · Goldbohm, R.A. · Brandt, P.A. van den
Keywords: Health · Leefomgeving en gezondheid · Cohort study · Dietary fat · Meat · Microscopic confirmation · Pancreatic cancer · carcinogen · heterocyclic amine · linoleic acid · nitroso derivative · polycyclic aromatic hydrocarbon · polyunsaturated fatty acid · adult · aged · article · cancer risk · cohort analysis · egg · fat intake · female · fish · food intake · food processing · human · major clinical study · male · meat · Netherlands · pancreas cancer · priority journal · Aged · Case-Control Studies · Cohort Studies · Dietary Fats · Female · Humans · Male · Meat · Middle Aged · Netherlands · Pancreatic Neoplasms · Questionnaires · Risk Factors
[Abstract]

10 Intragastric formation and modulation of N-nitrosodimethylamine in a dynamic in vitro gastrointestinal model under human physiological conditions
article 2004    
Author: Krul, C.A.M. · Zeilmaker, M.J. · Schothorst, R.C. · Havenaar, R.
Keywords: Biology · Physiological Sciences · Ascorbic acid · Codfish · Gastrointestinal model · N-nitrosodimethylamine · Nitrite · Toxicokinetic model · carcinogen · dimethylamine · dimethylnitrosamine · nitrate · nitrite · thiocyanate · article · fish · gastrointestinal tract · in vitro study · model · mouth flora · nitrosation · orange juice · physiology · quantitative analysis · saliva · simulation · statistical significance · stomach pH · tea · Animals · Antioxidants · Ascorbic Acid · Carcinogens · Citrus sinensis · Dimethylnitrosamine · Fishes · Flavonoids · Gastric Emptying · Gastric Juice · Humans · Hydrogen-Ion Concentration · Kinetics · Models, Biological · Nitric Oxide · Nitrites · Phenols · Species Specificity · Stomach · Tea · Thiocyanates · Clupea harengus · Pleuronectes platessa · Pollachius pollachius
[Abstract]

11 Myricetin stimulates the absorption of the pro-carcinogen PhIP
article 2006    
Author: Schutte, M.E. · Sandt, J.J.M. van de · Alink, G.M. · Groten, J.P. · Rietjens, I.M.C.M.
Keywords: Biology · Biomedical Research · ABC transporter · Apparent permeability · Caco-2 · Myricetin · PhIP · 2 amino 1 methyl 6 phenylimidazo[4,5 b]pyridine · carcinogen · cyclosporin A · glycoprotein P inhibitor · multidrug resistance protein 2 · myricetin · valspodar · absorption · article · cell differentiation · cell strain CACO 2 · cell transport · concentration (parameters) · excretion · human · human cell · intestine epithelium cell · priority journal · stimulation · Absorption · ATP-Binding Cassette Transporters · Caco-2 Cells · Carcinogens · Flavonoids · Humans · Imidazoles · Membrane Transport Proteins · Multidrug Resistance-Associated Proteins · Permeability
[Abstract]

12 Alcohol intake and ovarian cancer risk : A pooled analysis of 10 cohort studies
article 2006    
Author: Genkinger, J.M. · Hunter, D.J. · Spiegelman, D. · Anderson, K.E. · Buring, J.E. · Freudenheim, J.L. · Goldbohm, R.A. · Harnack, L. · Hankinson, S.E. · Larsson, S.C. · Leitzmann, M. · McCullough, M.L. · Marshall, J. · Miller, A.B. · Rodriguez, C. · Rohan, T.E. · Schatzkin, A. · Schouten, L.J. · Wolk, A. · Zhang, S.M. · Smith-Warner, S.A.
Keywords: Health · Food and Chemical Risk Analysis · Alcohol · Ovarian cancer · Pooled analysis · acetaldehyde · carcinogen · estrogen · folic acid · hormone · oral contraceptive agent · adult · aged · alcohol consumption · article · beer · body mass · cancer incidence · cancer risk · carcinogenesis · cohort analysis · female · hormone substitution · human · major clinical study · ovary cancer · oxidation · priority journal · prospective study · wine · Adult · Aged · Aged, 80 and over · Alcohol Drinking · Body Mass Index · Cohort Studies · Contraceptives, Oral · Female · Hormone Replacement Therapy · Humans · Menopause · Middle Aged · Ovarian Neoplasms · Parity · Pregnancy · Risk Factors
[PDF] [Abstract]

13 Human cytochrome P450 enzyme specificity for bioactivation of safrole to the proximate carcinogen 1′-hydroxysafrole
article 2004    
Author: Jeurissen, S.M.F. · Bogaards, J.J.P. · Awad, H.M. · Boersma, M.G. · Brand, W. · Fiamegos, Y.C. · Beek, T.A. van · Alink, G.M. · Sudhölter, E.J.R. · Cnubben, N.H.P. · Rietjens, I.M.C.M.
Keywords: Biology · Physiological Sciences · 1' hydroxysafrole · carcinogen · cytochrome P450 · cytochrome P450 2A6 · cytochrome P450 2C9 · cytochrome P450 2D6 · cytochrome P450 2E1 · safrole · unclassified drug · animal cell · article · enzyme activation · enzyme specificity · human · insect cell · microsome · nonhuman · reaction analysis · Biotransformation · Carcinogens · Cytochrome P-450 Enzyme System · Humans · Microsomes, Liver · Risk Assessment · Safrole · Statistics, Nonparametric · Substrate Specificity · Animalia · Insecta
[Abstract]

14 Time series analysis of benzo[a]pyrene-induced transcriptome changes suggests that a network of transcription factors regulates the effects on functional gene sets
article 2010    
Author: Delft, J.H.M. van · Mathijs, K. · Staal, Y.C.M. · Herwijnen, M.H.M. van · Brauers, K.J.J. · Boorsma, A. · Kleinjans, J.C.S.
Keywords: Nutrition · Biomedical Research · Carcinogen · Network · Time series · Transcription factor · Transcriptome · benzo[a]pyrene · immunoglobulin enhancer binding protein · Myc protein · serum response factor · transcription factor · transcription factor AP 1 · transcription factor E2F1 · transcriptome · amino acid metabolism · apoptosis · article · carcinogenesis · cell cycle G1 phase · cell cycle S phase · controlled study · correlation analysis · DNA adduct · DNA repair · down regulation · functional genomics · gene expression · gene regulatory network · hepatoma cell · human · human cell · lipid metabolism · named inventories, questionnaires and rating scales · proto oncogene · Short Time series Expression Miner · signal transduction · time series analysis · transcription regulation · tumor suppressor gene · upregulation
[Abstract]

15 The FEMA GRAS assessment of aromatic substituted secondary alcohols, ketones, and related esters used as flavor ingredients
article 2007    
Author: Adams, T.B. · McGowen, M.M. · Williams, M.C. · Cohen, S.M. · Feron, V.J. · Goodman, J.I. · Marnett, L.J. · Munro, I.C. · Portoghese, P.S. · Smith, R.L. · Waddell, W.J.
Keywords: Nutrition · Toxicology and Applied Pharmacology · Aromatic ketones · FEMA GRAS · Flavoring ingredients · 1 (1 methoxyphenyl) 1 penten 3 one · 1 phenyl 1 propanol · 1 phenyl 1,2 propanedione · 1 phenylethanol · 4 (4 methoxyphenyl) 2 butanone · 4 methyl 1 phenyl 2 pentanol · acetophenone · alcohol derivative · alpha methylphenethylbutyrate · benzoin · benzophenone · carcinogen · ester · flavoring agent · ketone · methyl beta naphthyl ketone · absorption · acute toxicity · flavor · genotoxicity · hydrolysis · metabolism · nonhuman · review · safety · urinary excretion · Alcohols · Animals · Benzophenones · Consumer Product Safety · Esters · Flavoring Agents · Food Industry · Humans · Ketones · No-Observed-Adverse-Effect Level · Phenylethyl Alcohol · Toxicity Tests · United States · United States Food and Drug Administration · Animalia
[Abstract]

16 Evaluation of the Xpa-Deficient Transgenic Mouse Model for Short-Term Carcinogenicity Testing: 9-Month Studies with Haloperidol, Reserpine, Phenacetin, and D-Mannitol
article 2004    
Author: Lina, B.A.R. · Woutersen, R.A. · Bruijntjes, J.P. · Benthem, J. van · Berg, J.A.H. van den · Monbaliu, J. · Thoolen, B.J.J.M. · Beems, R.B. · Kreijl, C.F. van
Keywords: Biology · Toxicology and Applied Pharmacology · Carcinogenicity testing · Carcinogens · DNA repair deficient · Knockout mice · Xpa · Xpa/p53 · haloperidol · mannitol · phenacetin · reserpine · animal experiment · animal tissue · article · cancer incidence · carcinogen testing · controlled study · DNA repair · evaluation · female · hyperplasia · kidney tumor · knockout mouse · male · maximum tolerated dose · mouse · nonhuman · priority journal · rare disease · survival · target organ · transgenic mouse · Administration, Oral · Animals · Carcinogenicity Tests · Diet · Disease Models, Animal · DNA-Binding Proteins · Dose-Response Relationship, Drug · Haloperidol · Mannitol · Mice · Mice, Inbred C57BL · Mice, Knockout · Mice, Transgenic · Neoplasms, Experimental · Phenacetin · Reproducibility of Results · Reserpine · Time Factors · Xeroderma Pigmentosum Group A Protein · Animalia · Mus musculus · Rodentia
[Abstract]

17 Human cytochrome P450 enzymes of importance for the bioactivation of methyleugenol to the proximate carcinogen 1′-hydroxymethyleugenol
article 2006    
Author: Jeurissen, S.M.F. · Bogaards, J.J.P. · Boersma, M.G. · Horst, J.P.F. ter · Awad, H.M. · Fiamegos, Y.C. · Beek, T.A. van · Alink, G.M. · Sudhölter, E.J.R. · Cnubben, N.H.P. · Rietjens, I.M.C.M.
Keywords: Biology · Biomedical Research · 1' hydroxymethyleugenol · barbituric acid derivative · carcinogen · cytochrome P450 · cytochrome P450 1A2 · cytochrome P450 2A6 · cytochrome P450 2C19 · cytochrome P450 2C9 · cytochrome P450 2D6 · methyleugenol · unclassified drug · article · carcinogenicity · concentration (parameters) · enzyme activation · enzyme kinetics · enzyme specificity · enzyme substrate · human · hydroxylation · incubation time · insect cell · lifestyle · liver microsome · nonhuman · sensitivity analysis · smoking · Aryl Hydrocarbon Hydroxylases · Benzoflavones · Biotransformation · Carcinogens · Cell Line · Cytochrome P-450 CYP1A2 · Cytochrome P-450 Enzyme System · Enzyme Inhibitors · Eugenol · Flavoring Agents · Humans · Kinetics · Microsomes, Liver · Mixed Function Oxygenases · Recombinant Proteins · Risk Assessment · Sulfaphenazole · Insecta
[Abstract]

18 Risk estimation for carcinogens based on epidemiological data: A structured approach, illustrated by an example on chromium
article 2006    
Author: Goldbohm, R.A. · Tielemans, E.L.J.P. · Heederik, D. · Rubingh, C.M. · Dekkers, S. · Willems, M.I. · Dinant Kroese, E.
Keywords: Health · Food and Chemical Risk Analysis · Chromium · Epidemiology · Excess lifetime risk · Lung cancer · Potency · Probabilistic · Risk assessment · Sensitivity analysis · Uncertainty · Variability · carcinogen · chromium · analytic method · article · biometry · calculation · cancer mortality · cancer risk · case control study · cause of death · cohort analysis · confidence interval · data analysis · epidemiological data · evidence based medicine · experimentation · exposure · human · information processing · life table · lifespan · lung cancer · mathematical model · methodology · observational study · occupational exposure · priority journal · publication · qualitative analysis · quantitative analysis · reproducibility · risk assessment · risk factor · sensitivity analysis · statistical model · uncertainty · Animals · Carcinogens, Environmental · Chromium · Data Interpretation, Statistical · Epidemiologic Methods · Humans · Lung Neoplasms · Risk Assessment · Animalia
[Abstract]

19 Hazard assessment of nitrosamine and nitramine by-products of amine-based CCS: Alternative approaches
article 2015    
Author: Buist, H.E. · Devito, S. · Goldbohm, R.A. · Stierum, R.H. · Venhorst, J. · Kroese, E.D.
Keywords: Nutrition · Carbon capture and storage · Carcinogenicity · Cell transformation assay · Mutagenicity · Nitramines · Nitrosamines · Predictive in vitro models · Predictive in vivo models · QSARs · Transgenic animal test · Aniline derivative · Nitrobenzene derivative · Animal · Biological model · Carbon sequestration · Carcinogen testing · Cell transformation · Chemical structure · Chemically induced · Chemistry · LD50 · Mutagen testing · Neoplasm · Procedures · Quantitative structure activity relation · Risk assessment · Transgenic mouse · Aniline Compounds · Animals · Carbon Sequestration · Carcinogenicity Tests · Cell Transformation, Neoplastic · Lethal Dose 50 · Mice, Transgenic · Models, Biological · Molecular Structure · Mutagenicity Tests · Neoplasms · Nitrobenzenes · Quantitative Structure-Activity Relationship · Food and Nutrition · Healthy Living · Life · RAPID - Risk Analysis for Products in Development · ELSS - Earth, Life and Social Sciences
[Abstract]

20 IPCS guidelines for the monitoring of genotoxic effects of carcinogens in humans
article 2000    
Author: Albertini, R.J. · Anderson, D. · Douglas, G.R. · Hagmar, L. · Hemminki, K. · Merlo, F. · Natarajan, A.T. · Norppa, H. · Shuker, D.E.G. · Tice, R. · Waters, M.D. · Aitio, A.
Keywords: Biomarkers · Biomonitoring · Genotoxic carcinogens · Guideline · Human populations · WHO · carcinogen · hypoxanthine phosphoribosyltransferase · blood analysis · carcinogenicity · chromosome aberration · comet assay · cytogenetics · DNA adduct · DNA damage · ethics · fluorescence in situ hybridization · gene mutation · genotoxicity · human · micronucleus test · patient monitoring · practice guideline · priority journal · protein binding · review · risk assessment · sampling · sister chromatid exchange · statistical analysis · technique · Carcinogens · Chromosome Aberrations · DNA Damage · Environmental Health · Environmental Monitoring · Humans · Hypoxanthine Phosphoribosyltransferase · In Situ Hybridization, Fluorescence · International Cooperation · Lymphocytes · Micronucleus Tests · Mutagens · Sister Chromatid Exchange · Toxicity Tests · United Nations · World Health Organization
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 21 found. Next | Sort by date