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1 Inhibition of glycosaminoglycan incorporation influences collagen network formation during cartilage matrix production
article 2009    
Author: Bastiaansen-Jenniskens, Y.M. · Koevoet, W. · Jansen, K.M.B. · Verhaar, J.A.N. · Groot, J. de · Vanosch, G.J.V.M.
Keywords: Biology · Biomedical Research · Cartilage matrix · Glycosaminoglycan · Cartilage cell · Cartilage degeneration · Cell culture · Concentration response · Cross linking · Alginates · Animals · Cattle · Chondrocytes · Collagen Type II · Gene Expression · Glucuronic Acid · Glycosaminoglycans · Glycosides · Hexuronic Acids · SOX9 Transcription Factor · Tissue Culture Techniques · Bovinae
[Abstract]

2 Degeneration, inflammation, regeneration, and pain/disability in dogs following destabilization or articular cartilage grooving of the stifle joint
article 2008    
Author: Frost-Christensen, L.N. · Mastbergen, S.C. · Vianen, M.E. · Hartog, A. · Groot, J. de · Voorhout, G. · Wees, A.M.C. van · Lafeber, F.P.J.G. · Hazewinkel, H.A.W.
Keywords: Health · ACLT · Gait · Groove-model · Meniscectomy · Osteoarthritis · Animal experiment · Animal model · Animal tissue · Anterior cruciate ligament injury · Article · Articular cartilage · Cartilage cell · Controlled study · Disease model · Dog · Gait · Joint degeneration · Knee osteoarthritis · Knee pain · Knee radiography · Nonhuman · Osteophyte · Physical disability · Priority journal · Synovitis · Tissue regeneration · Animals · Anterior Cruciate Ligament · Arthralgia · Cartilage, Articular · Chondrocytes · Dogs · Gait · Inflammation · Joint Instability · Models, Animal · Osteoarthritis · Osteophyte · Regeneration · Stifle
[Abstract]

3 Degenerated and healthy cartilage are equally vulnerable to blood-induced damage
article 2008    
Author: Jansen, N.W.D. · Roosendaal, G. · Bijlsma, J.W.J. · Groot, J. de · Theobald, M. · Lafeber, F.P.J.G.
Keywords: Health · Matrix metalloproteinase · Proteoglycan · Aged · Article · Blood · Cartilage cell · Cartilage degeneration · Controlled study · Enzyme activity · Female · Hemarthrosis · Human · Human tissue · Male · Osteoarthritis · Priority journal · Proteoglycan synthesis · Aged · Blood · Cartilage, Articular · Chondrocytes · Female · Hemarthrosis · Humans · Male · Matrix Metalloproteinases · Middle Aged · Osteoarthritis · Proteoglycans · Tissue Culture Techniques · Food and Nutrition · Healthy Living
[Abstract]

4 Matrix degradation by chondrocytes cultured in alginate : IL-1β induces proteoglycan degradation and proMMP synthesis but does not result in collagen degradation
article 1998    
Author: Beekman, B. · Verzijl, N. · Roos, J.A.D.M. de · TeKoppele, J.M.
Keywords: Biology · Biomedical Research · Matrix degradation · Matrix metalloproteinases · alpha amino 3 hydroxy 5 methyl 4 isoxazolepropionic acid · collagen · glycosaminoglycan · interleukin 1beta · metalloproteinase · proteoglycan · cartilage cell · degradation · enzyme synthesis · extracellular matrix · Alginates · Animals · Cattle · Cells, Cultured · Chondrocytes · Collagen · Extracellular Matrix · Interleukin-1 · Metalloendopeptidases · Microspheres · Proteoglycans
[Abstract]

5 Age-related decrease in proteoglycan synthesis of human articular chondrocytes: The role of nonenzymatic glycation
article 1999    
Author: Groot, J. de · Verzijl, N. · Bank, R.A. · Lafeber, F.P.J.G. · Bijlsma, J.W.J. · TeKoppele, J.M.
Keywords: Health Biology · Biomedical Research · age · article · articular cartilage · cartilage cell · glycation · human · human tissue · pathogenesis · priority journal · proteoglycan synthesis · rheumatic disease · Adult · Aged · Aged, 80 and over · Aging · Arginine · Cartilage, Articular · Cross-Linking Reagents · Extracellular Matrix · Glycosylation End Products, Advanced · Humans · Lysine · Middle Aged · Osteoarthritis · Proteoglycans · Ribose
[Abstract]

6 Doxycycline inhibits collagen synthesis by differentiated articular chondrocytes.
article 1998    
Author: TeKoppele, J.M. · Beekman, B. · Verzijl, N. · Koopman, J.L. · Groot, J. de · Bank, R.A.
Keywords: Biology · Biomedical Research · antiinfective agent · collagen · doxycycline · metalloproteinase · protein synthesis inhibitor · proteinase inhibitor · animal · article · articular cartilage · biosynthesis · cartilage cell · cattle · cell culture · cytology · dog · drug antagonism · metabolism · osteoarthritis · Animals · Anti-Bacterial Agents · Cartilage, Articular · Cattle · Cells, Cultured · Chondrocytes · Collagen · Dogs · Doxycycline · Metalloendopeptidases · Osteoarthritis · Protease Inhibitors · Protein Synthesis Inhibitors
[Abstract]

7 Elevation of cartilage AGEs does not accelerate initiation of canine experimental osteoarthritis upon mild surgical damage
article 2012    
Author: Vos, P.A.J.M. · Degroot, J. · Barten-Van Rijbroek, A.D. · Zuurmond, A.-M. · Bijlsma, J.W.J. · Mastbergen, S.C. · Lafeber, F.P.J.G.
Keywords: Health · canine · non-enzymatic glycation · osteoarthritis · pentosidine · proteoglycan · advanced glycation end product · carbohydrate · pentosidine · proteoglycan · ribose · threose · unclassified drug · animal cell · animal experiment · animal model · animal tissue · article · bone turnover · cartilage · cartilage cell · cartilage injury · controlled study · experimental dog · female · histopathology · in vivo study · joint degeneration · knee surgery · nonhuman · osteoarthritis · priority journal · synovitis · tissue level · Healthy for Life · Healthy Living · Life · MHR - Metabolic Health Research PHS - Pharmacokinetics & Human Studies · EELS - Earth, Environmental and Life Sciences
[Abstract]

8 Contribution of collagen network features to functional properties of engineered cartilage
article 2008    
Author: Bastiaansen-Jenniskens, Y.M. · Koevoet, W. · Bart, A.C.W. de · Linden, J.C. van der · Zuurmond, A.M. · Weinans, H. · Verhaar, J.A.N. · Osch, G.J.V.M. van · Groot, J. de
Keywords: Health · Cartilage · Chondrocyte · Collagen · Crosslinks · Mechanical properties · 3 aminopropionitrile · alginic acid · collagen · interstitial collagenase · water · animal cell · animal cell culture · article · articular cartilage · cartilage cell · cartilage matrix · cattle · collagen degradation · controlled study · cross linking · nonhuman · priority journal · protein degradation · rigidity · tissue engineering · water retention · Alginates · Aminopropionitrile · Animals · Biomechanics · Cartilage, Articular · Cattle · Cell Count · Cells, Cultured · Chondrocytes · Extracellular Matrix · Fibrillar Collagens · Gene Expression · Matrix Metalloproteinases · Osteoarthritis · Permeability · Phenotype · Regeneration · Stress, Mechanical · Time Factors · Tissue Engineering
[Abstract]

9 Accumulation of advanced glycation end products decreases collagen turnover by bovine chondrocytes
article 2001    
Author: Groot, J. de · Verzijl, N. · Budde, M. · Bijlsma, J.W.J. · Lafeber, F.P.J.G. · TeKoppele, J.M.
Keywords: Biology · Biomedical Research · Advanced glycation end product · Alginate culture · Cartilage · Chondrocyte · Collagen · Matrix metalloproteinase · Turnover · advanced glycation end product · alginic acid · collagen · matrix metalloproteinase · ribose · animal cell · article · articular cartilage · cartilage cell · cattle · cell culture · collagen defect · collagen degradation · collagen synthesis · controlled study · culture medium · enzyme activity · extracellular matrix · nonhuman · osteoarthritis · priority journal · reaction time · Animals · Cattle · Cells, Cultured · Chondrocytes · Collagen · Enzyme Precursors · Extracellular Matrix · Glycosylation End Products, Advanced · Matrix Metalloproteinases · Osteoarthritis · Ribose · Bovinae
[Abstract]

10 Synthesis of collagen by bovine chondrocytes cultured in alginate; posttranslational modifications and cell-matrix interaction
article 1997    
Author: Beekman, B. · Verzijl, N. · Bank, R.A. · Von Der Mark, K. · TeKoppele, J.M.
Keywords: Biology · Biomedical Research · Alginate beads · Articular chondrocyte · Collagen · Collagen crosslinks · Posttranslational modification · Proteoglycan · 3 aminopropionitrile · alginic acid · collagen · integrin · pyridinoline · animal cell · binding affinity · cartilage cell · cell interaction · cell proliferation · collagen synthesis · nonhuman · priority journal · protein cross linking · protein processing · Alginates · Amino Acid Sequence · Amino Acids · Aminopropionitrile · Animals · Cartilage, Articular · Cattle · Cell Division · Cells, Cultured · Collagen · DNA · Extracellular Matrix · Glucuronic Acid · Glycosylation · Hexuronic Acids · Kinetics · Oligopeptides · Protein Processing, Post-Translational · Proteoglycans · Time Factors · Animalia · Bos taurus · Bovinae
[Abstract]

11 Soluble biomarkers of cartilage and bone metabolism in early proof of concept trials in psoriatic arthritis: Effects of adalimumab versus placebo
article 2010    
Author: Tak, P.P. · Kuijk, A.W.R. van · Groot, J. de · Koeman, R.C. · Sakkee, N. · Baeten, D.L. · Gerlag, D.M.
Keywords: Health · Biomedical Research · adalimumab · amino terminal cross linked telopeptide of type 1 collagen · C propeptide of type 2 collagen · carboxy terminal cross linked telopeptide of type 1 collagen · cartilage oligomeric matrix protein · collagen type 1 · collagen type 2 · osteocalcin · placebo · procollagen · procollagen serum type 1 amino terminal propeptide · stromelysin · unclassified drug · article · bone metabolism · cartilage cell · cartilage metabolism · clinical article · clinical trial · controlled clinical trial · controlled study · correlation analysis · disease marker · drug efficacy · human · ossification · protein analysis · protein blood level · protein degradation · protein function · protein synthesis · psoriatic arthritis · randomized controlled trial · tissue metabolism
[PDF] [Abstract]

12 Monounsaturated and Saturated, but Not n-6 Polyunsaturated Fatty Acids Decrease Cartilage Destruction under Inflammatory Conditions: A Preliminary Study
article 2013    
Author: Bastiaansen-Jenniskens, Y.M. · Siawash, M. · Lest, C.H.A. van de · Verhaar, J.A.N. · Kloppenburg, M. · Zuurmond, A.M. · Stojanovic-Susulic, V. · Osch, G.J.V.M. van · Clockaerts, S.
Keywords: Health · Cartilage · Chondrocyte · Fatty acids · Collagenase 3 · Disintegrin · Glyceraldehyde 3 phosphate dehydrogenase · Glycosaminoglycan · Interstitial collagenase · Lactate dehydrogenase · Linoleic acid · Monounsaturated fatty acid · Oleic acid · Palmitic acid · Polyunsaturated fatty acid · Prostaglandin E2 · Prostaglandin synthase · Saturated fatty acid · Tumor necrosis factor alpha · Adult · Aged · Cartilage cell · Cartilage degeneration · Cell viability · Controlled study · Cytotoxicity · Enzyme release · Gene expression · Human · Human cell · Human tissue · Immunoassay · Inflammation · Limit of quantitation · Lipid transport · Reverse transcription polymerase chain reaction · Total knee replacement · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · EELS - Earth, Environmental and Life Sciences
[Abstract]

13 The canine 'groove' model, compared with the ACLT model of osteoarthritis
article 2002    
Author: Marijnissen, A.C.A. · Roermund, P.M. van · TeKoppele, J.M. · Bijlsma, J.W.J. · Lafeber, F.P.J.G.
Keywords: Biology · Biomedical Research · Canine model · Cartilage · Osteoarthritis · Proteoglycans · collagen · collagenase 3 · interstitial collagenase · matrix protein · proteoglycan · stromelysin · animal experiment · animal model · animal tissue · anterior cruciate ligament · article · articular cartilage · biochemistry · cartilage cell · cartilage degeneration · collagen degradation · controlled study · disease model · disease severity · dog · enzyme activity · evaluation · female · femur condyle · histopathology · joint stability · knee · nonhuman · osteoarthritis · priority journal · protein depletion · synovial fluid · synovitis · tissue injury · weight bearing · Animals · Cartilage, Articular · Chondrocytes · Collagen · Collagenases · Dogs · Female · Matrix Metalloproteinase 1 · Matrix Metalloproteinase 13 · Matrix Metalloproteinase 3 · Models, Animal · Osteoarthritis · Proteoglycans · Synovial Fluid · Weight-Bearing
[Abstract]

14 Biochemical and functional modulation of the cartilage collagen network by IGF1, TGFβ2 and FGF2
article 2006    
Author: Jenniskens, Y.M. · Koevoet, W. · Bart, A.C.W. de · Weinans, H. · Jahr, H. · Verhaar, J.A.N. · Groot, J. de · Osch, G.J.V.M. van
Keywords: Biology · Biomedical Research · Chondrocyte · Cross-links · Growth factors · Mechanical properties · Proteoglycans · Alginic acid · Collagen fiber · Fibroblast growth factor 2 · Matrix metalloproteinase · Proteoglycan · Pyridinoline · Somatomedin C · Transforming growth factor beta2 · Animal cell · Animal tissue · Cartilage cell · Cartilage matrix · Collagen synthesis · Controlled study · Cow · Culture medium · Enzyme activity · Enzyme analysis · Nonhuman · Permeability · Protein cross linking · Protein determination · Protein function · Protein protein interaction · Rigidity · Aggrecans · Animals · Biomechanics · Cartilage, Articular · Cattle · Cells, Cultured · Chondrocytes · Collagen · Collagen Type II · DNA · Extracellular Matrix · Fibroblast Growth Factor 2 · Forelimb · Gene Expression · Immunohistochemistry · Insulin-Like Growth Factor I · Matrix Metalloproteinases · Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase · Protein-Lysine 6-Oxidase · Proteoglycans · Transforming Growth Factor beta2
[Abstract]

15 TGFβ affects collagen cross-linking independent of chondrocyte phenotype but strongly depending on physical environment
article 2008    
Author: Bastiaansen-Jenniskens, Y.M. · Koevoet, W. · Bart, A.C.W. de · Zuurmond, A.-M. · Bank, R.A. · Verhaar, J.A.N. · Groot, J. de · Osch, G.J.V.M. van
Keywords: Biology · Alginate · Body fluids · Cell proliferation · Cells · Cobalt · Cobalt compounds · Collagen · Colloids · Electron energy levels · Fibroblasts · Gelation · Matrix algebra · Painting · Photoacoustic effect · Shape memory effect · Technology · Tissue · Tissue culture · Tissue engineering · Alginate gel (AG) · Cartilage tissue engineering · Cell populations · Chondrocyte · Chondrocytes · Collagen cross-linking · Collagen deposition · Cultures (Traditional) · Matrix formation · Mechanical stressing · Monolayer cultures · Physical environments · Primary cells · Shape memory alloy (SMA) fibers · Smooth muscle actin (SMA) · Tissue culture plastic (TCP) · Transforming Growth Factor (TGF) · Cell culture · Alginic acid · Alpha smooth muscle actin · Collagen · Transforming growth factor beta · Actin · Collagen type 1 · Collagen type 2 · Cross linking reagent · DNA · Transcription factor Sox9 · Transforming growth factor beta2 · Animal cell · Animal tissue · Article · Calf (bovine) · Cartilage cell · Cell population · Controlled study · Cross linking · Drug effect · Fibroblast · Nonhuman · Phenotype · Priority journal · Upregulation · Animal · Cattle · Cell culture · Cytology · Extracellular matrix · Gene expression regulation · Genetics · Immunohistochemistry · Metabolism · Smooth muscle · Actins · Animals · Cattle · Cells, Cultured · Chondrocytes · Collagen · Collagen Type I · Collagen Type II · Cross-Linking Reagents · DNA · Extracellular Matrix · Gene Expression Regulation · Immunohistochemistry · Muscle, Smooth · Phenotype · SOX9 Transcription Factor · Transforming Growth Factor beta2
[PDF] [Abstract]

Search results also available in MS Excel format.

Showing 1 to 15 of 15 found. | Sort by date