Repository hosted by TU Delft Library

Home · Contact · About · Disclaimer ·
 

Search results also available in MS Excel format.

Showing 1 to 4 of 4 found. | Sort by date

1 Are zebrafish larvae suitable for assessing the hepatotoxicity potential of drug candidates?
article 2015    
Author: Mesens, N. · Crawfordb, A.D. · Menke, A. · Hung, P.D. · Goethem, F. van · Nuyts, R. · Hansen, E. · Wolterbeek, A. · Gompel, J. van · Witte, P. de · Esguerra, C.V.
Keywords: Nutrition · Zebrafish larvae · Screening assay · Lfabp10a · Hepatotoxicity · DILI · Alpidem · Amiodarone · Bosentan · Buspirone · Diclofenac · Fatty acid binding protein · Fatty acid binding protein 10a · Glycogen · Ketorolac · Nefazodone · Paracetamol · Reactive oxygen metabolite · Rosiglitazone · Tacrine · Tamoxifen · Tetracycline · Troglitazone · Unclassified drug · Zolpidem · Adult · Animal tissue · Cell vacuole · Cholestasis · Circulation · Concentration response · Controlled study · Drug safety · Female · Glycogen analysis · Heart rate · Histology · Histopathology · In situ hybridization · Larval stage · Liver cell · Liver level · Liver size · Liver toxicity · Male · Mitochondrial membrane · Mitochondrial toxicity · Molecular cloning · Nonhuman · Protein expression · Steatosis · Toxicity testing · Zebra fish · Danio rerio · Food and Nutrition · Healthy Living · Life · RAPID - Risk Analysis for Products in Development · ELSS - Earth, Life and Social Sciences
[Abstract]

2 Evaluation of a subchronic (13-week) oral toxicity study, preceded by an in utero exposure phase, with arachidonic acid oil derived from Mortierella alpina in rats
article 2000    
Author: Hempenius, R.A. · Lina, B.A.R. · Haggitt, R.C.
Keywords: Arachidonic acid oil · Clinical chemistry · Haematology · Histopathology · Organ weights · Rat · Reproductive indices · Safety · alkaline phosphatase · arachidonic acid · cholesterol · corn oil · creatinine · docosahexaenoic acid · fat droplet · oil · phospholipid · triacylglycerol · urea · animal experiment · article · cell vacuole · controlled study · enzyme activity · fertility · food intake · food poisoning · food safety · histopathology · lactation · lipid composition · lipogranuloma · mating · Mortierella alpina · neurotoxicity · nonhuman · organ weight · pregnancy · prenatal exposure · rat · toxicity testing · weaning · weight gain · Administration, Oral · Animals · Arachidonic Acids · Body Weight · Docosahexaenoic Acids · Dose-Response Relationship, Drug · Female · Fermentation · Fish Oils · Humans · Infant Food · Infant Nutrition Physiology · Infant, Newborn · Liver · Male · Mortierella · Mutagenicity Tests · Pregnancy · Prenatal Exposure Delayed Effects · Rats · Rats, Wistar · Reproduction · Animalia · Ara · Fungi · Mortierella alpina · Rodentia · Zea mays
[Abstract]

3 Broad expression of Toll-like receptors in the human central nervous system
article 2002    
Author: Bsibsi, M. · Ravid, R. · Gveric, D. · Noort, J.M. van
Keywords: Health · Central nervous system · Oligodendrocytes · Toll-like receptors · Toll like receptor · Unclassified drug · Alzheimer disease · Cell vacuole · Controlled study · Human tissue · Immunocytochemistry · Parkinson disease · Pick presenile dementia · Protein expression · Aged · Aged, 80 and over · Astrocytes · Cells, Cultured · Central Nervous System · Central Nervous System Infections · Drosophila Proteins · Encephalitis · Female · Gene Expression Regulation · Humans · Immune System · Immunohistochemistry · Male · Membrane Glycoproteins · Microglia · Middle Aged · Multiple Sclerosis · Neuroglia · Oligodendroglia · Receptors, Cell Surface · RNA, Messenger · Toll-Like Receptor 2 · Toll-Like Receptor 3 · Toll-Like Receptor 4 · Toll-Like Receptors
[Abstract]

4 Zebrafish embryotoxicity test for developmental (neuro)toxicity: Demo case of an integrated screening approach system using anti-epileptic drugs
article 2014    
Author: Beker van Woudenberg, A. · Snel, C. · Rijkmans, E. · Groot, D. de · Bouma, M. · Hermsen, S. · Piersma, A. · Menke, A. · Wolterbeek, A.
Keywords: Biology · Antiepileptic drugs · Behavior · Developmental (neuro)toxicity · Gene expression · Histopathology · Integrated test strategy · Kinetics · Zebrafish embryotoxicity test (ZET) · Anticonvulsive agent · Carbamazepine · Cytochrome P450 26A1 · Ethosuximide · Etiracetam · Valproic acid · ALDH1A2 gene · Animal cell · Animal experiment · Animal model · Animal tissue · Case study · Cell vacuole · Concentration (parameters) · Controlled study · CYP26A1 gene · Demo case study · Developmental toxicity · Edema · Embryo · Embryotoxicity · Experimental design · Female · Gene · Gene expression · Histopathology · In situ hybridization · Larva · Liver cell · Male · Morphology · Motor activity · Nerve degeneration · Neurotoxicity · Nonhuman · Nucleotide sequence · Pericardial disease · Pericardial edema · Phenotype · Predictive value · Sensitivity analysis · Swimming · Toxicity testing · Toxicokinetics · Whole mount in situ hybridization · Zebra fish · Zebrafish embryotoxicity test · Biomedical Innovation · Healthy Living · Life · RAPID - Risk Assessment Products in Development · ELSS - Earth, Life and Social Sciences
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 4 of 4 found. | Sort by date