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Showing 1 to 9 of 9 found. | Sort by date

1 Inhibition of urokinase-type and tissue-type plasminogen activator - Mediated plasminogen activation by doxycycline
article 1996    
Author: Hanemaaijer, R. · Visser, H. · Hoogen, C.M. van den · Sorsa, T. · Hinsbergh, V.W.M. van
Keywords: Biology · doxycycline · tissue plasminogen activator · urokinase · conference paper · fibrinolysis · human · plasminogen activation · priority journal
[Abstract]

2 Inhibition of MMP synthesis by doxycycline and chemically modified tetracyclines (CMTs) in human endothelial cells
article 1998    
Author: Hanemaaijer, R. · Visser, H. · Koolwijk, P. · Sorsa, T. · Salo, T. · Golub, L.M. · Hinsbergh, V.W. van
Keywords: Health · Anti-Bacterial Agents · Cells, Cultured · Doxycycline · Endothelium · Humans · Metalloendopeptidases · Protease Inhibitors · Tetracyclines · Tetradecanoylphorbol Acetate · Tumor Necrosis Factor-alpha
[Abstract]

3 Impact of galacto-oligosaccharides on the gut microbiota composition and metabolic activity upon antibiotic treatment during in vitro fermentation
article 2014    
Author: Ladirat, S.E. · Schuren, F.H.J. · Schoterman, M.H.C. · Nauta, A. · Gruppen, H. · Schols, H.A.
Keywords: Biology · Amoxicillin · Ciprofloxacin · Clindamycin · Doxycycline · Phylogenetic microarray · Prebiotic · Biomedical Innovation · Healthy Living · Life · MSB - Microbiology and Systems Biology · ELSS - Earth, Life and Social Sciences
[Abstract]

4 Doxycycline inhibits collagen synthesis by differentiated articular chondrocytes.
article 1998    
Author: TeKoppele, J.M. · Beekman, B. · Verzijl, N. · Koopman, J.L. · Groot, J. de · Bank, R.A.
Keywords: Biology · Biomedical Research · antiinfective agent · collagen · doxycycline · metalloproteinase · protein synthesis inhibitor · proteinase inhibitor · animal · article · articular cartilage · biosynthesis · cartilage cell · cattle · cell culture · cytology · dog · drug antagonism · metabolism · osteoarthritis · Animals · Anti-Bacterial Agents · Cartilage, Articular · Cattle · Cells, Cultured · Chondrocytes · Collagen · Dogs · Doxycycline · Metalloendopeptidases · Osteoarthritis · Protease Inhibitors · Protein Synthesis Inhibitors
[Abstract]

5 Lack of effect of doxycycline on disease activity and joint damage in patients with rheumatoid arthritis. A double blind, placebo controlled trial
article 2001    
Author: Laan, W. van der · Molenaar, E. · Ronday, K. · Verheijen, J. · Breedveld, F. · Greenwald, R. · Dijkmans, B. · Tekoppele, J.
Keywords: Health · Biomedical Research · Doxycycline · Pyridinolines · Rheumatoid arthritis · deoxypyridinoline · doxycycline · placebo · pyridinoline · clinical examination · clinical trial · controlled clinical trial · controlled study · crossover procedure · disease activity · double blind procedure · erythrocyte sedimentation rate · foot radiography · hand radiography · joint destruction · joint stiffness · laboratory test · major clinical study · randomized controlled trial · scoring system · Adolescent · Adult · Aged · Aged, 80 and over · Analysis of Variance · Arthritis, Rheumatoid · Chi-Square Distribution · Cross-Over Studies · Dose-Response Relationship, Drug · Double-Blind Method · Doxycycline · Drug Administration Schedule · Female · Follow-Up Studies · Humans · Male · Middle Aged · Pain Measurement · Reference Values · Severity of Illness Index · Treatment Failure · Treatment Outcome
[Abstract]

6 Matrix metalloproteinase-8 is expressed in rheumatoid synovial fibroblasts and endothelial cells: Regulation by tumor necrosis factor-α and doxycycline
article 1997    
Author: Hanemaaijer, R. · Sorsa, T. · Konttinen, Y.T. · Ding, Y. · Sutinen, M. · Visser, H. · Hinsbergh, V.W.M. van · Helaakoski, T. · Kainulainen, T. · Rönkä, H. · Tschesche, H. · Salo, T.
Keywords: Arthritis, Rheumatoid · Catalysis · Cells, Cultured · Collagenases · Doxycycline · Endothelium · Endothelium, Vascular · Enzyme Inhibitors · Fibroblasts · Glycosylation · Humans · Matrix Metalloproteinase 8 · RNA, Messenger · Synovial Membrane · Tetradecanoylphorbol Acetate · Tumor Necrosis Factor-alpha · Up-Regulation
[PDF] [Abstract]

7 Clinical trial of doxycycline for matrix metalloproteinase-9 inhibition in patients with an abdominal aneurysm doxycycline selectively depletes aortic wall neutrophils and cytotoxic t cells
article 2009    
Author: Lindeman, J.H.N. · Abdul-Hussien, H. · Bockel, J.H. van · Wolterbeek, R. · Kleemann, R.
Keywords: Health · Aneurysm · Immunology · Inflammation · Molecular biology · Trials · Doxycycline · Gelatinase B · Granulocyte colony stimulating factor receptor · Interleukin 13 · Interleukin 6 · Interleukin 8 · Antiinfective agent · CCAAT enhancer binding protein · Enzyme inhibitor · IL6 protein, human · Transcription factor AP 1 · Transcription factor RelA · Abdominal aorta aneurysm · Aged · Cytotoxic T lymphocyte · Drug effect · Drug megadose · Drug tolerability · Enzyme inhibition · Aortic Aneurysm, Abdominal · CCAAT-Enhancer-Binding Proteins · Doxycycline · Enzyme Inhibitors · Matrix Metalloproteinase 9 · Middle Aged · Neutrophils · T-Lymphocytes, Cytotoxic · Vasculitis
[PDF] [Abstract]

8 Doxycycline therapy for abdominal aneurysm: Improved proteolytic balance through reduced neutrophil content
article 2009    
Author: Abdul-Hussien, H. · Hanemaaijer, R. · Verheijen, J.H. · Bockel, J.H. van · Geelkerken, R.H. · Lindeman, J.H.N.
Keywords: Biology · Biomedical Research · antihypertensive agent · antithrombocytic agent · cystatin C · cysteine proteinase · doxycycline · gelatinase B · hydroxymethylglutaryl coenzyme A reductase inhibitor · messenger RNA · neutrophil collagenase · stromelysin · tissue inhibitor of metalloproteinase 1 · abdominal aorta aneurysm · adult · aged · aorta wall · article · clinical article · clinical trial · controlled clinical trial · controlled study · dose response · drug effect · drug megadose · drug tolerability · enzyme activity · enzyme assay · female · gene expression · human · human tissue · immunohistochemistry · low drug dose · male · neutrophil · polymerase chain reaction · priority journal · protein degradation · quantitative analysis · randomized controlled trial · treatment duration · Western blotting · Aged · Aged, 80 and over · Aorta, Abdominal · Aortic Aneurysm, Abdominal · Cardiovascular Agents · Cystatin C · Cysteine Endopeptidases · Dose-Response Relationship, Drug · Doxycycline · Female · Gene Expression Regulation, Enzymologic · Humans · Male · Matrix Metalloproteinases · Middle Aged · Neutrophil Infiltration · Neutrophils · Prospective Studies · Protease Inhibitors · RNA, Messenger · Time Factors · Tissue Inhibitor of Metalloproteinase-1 · Treatment Outcome · Vascular Surgical Procedures
[Abstract]

9 Doxycycline inhibits collagen synthesis by bovine chondrocytes cultured in alginate
article 1997    
Author: Beekman, B. · Verzijl, N. · Roos, J.A.D.M.de · Koopman, J.L. · Tekoppele, J.M.
Keywords: Biology · Biomedical Research · alginic acid · cysteine · methionine · collagen · glucuronic acid · hexuronic acid · messenger RNA · protein synthesis inhibitor · sulfur · articular cartilage · cell culture · cell proliferation · collagen synthesis · metabolic inhibition · nonhuman · osteoarthritis · phenotype · animal · biosynthesis · culture technique · cytology · dose response · drug effect · genetic transcription · metabolism · metacarpophalangeal joint · methodology · protein synthesis · Alginates · Animals · Cartilage, Articular · Cattle · Cell Culture Techniques · Cell Division · Cell Survival · Collagen · Cysteine · DNA · Dose-Response Relationship, Drug · Doxycycline · Glucuronic Acid · Hexuronic Acids · Kinetics · Metacarpophalangeal Joint · Methionine · Protein Biosynthesis · Protein Synthesis Inhibitors · RNA, Messenger · Sulfur Radioisotopes · Transcription, Genetic
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 9 of 9 found. | Sort by date