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Showing 1 to 11 of 11 found. | Sort by date

1 Lactobacilli as live vaccine delivery vectors: Progress and prospects
article 2002    
Author: Seegers, J.F.M.L.
Keywords: Health · Antigens · Cloning · Immunology · Biotechnology · Cytokine · Drug carrier · Immunoglobulin A · Immunoglobulin G · Immunoglobulin M · Influenza vaccine · Live vaccine · Neutralizing antibody · Cytokine production · Drug delivery system · Drug effect · Gene expression · Immune response · Immunomodulation · Lactic acid bacterium · Molecular cloning · Bacterial Vaccines · Cloning, Molecular · Drug Delivery Systems · Gastrointestinal Diseases · Humans · Lactobacillus · Peptide Fragments · Probiotics · Recombinant Proteins · Species Specificity · Tetanus Toxin · Vaccination · Vaccines, Synthetic · Bacteria (microorganisms) · Lactobacillus · Negibacteria
[Abstract]

2 Lactic acid bacteria as antigen delivery vehicles for oral immunization purposes
article 1998    
Author: Pouwels, P.H. · Leer, R.J. · Shaw, M. · Heijne Den Bak-Glashouwer, M.J. · Tielen, F.D. · Smit, E. · Martinez, B. · Jore, J. · Conway, P.L.
Keywords: Nutrition · Adherence · Expression vector · Lactobacillus · Surface protein · Vaccine · Antigen · Bacterial protein · Membrane protein · Antigen presentation · Bacterial colonization · Bacterium adherence · Developing country · Drug delivery system · Epithelium cell · Expression vector · Immunization · Immunogenicity · Lactic acid bacterium · Lactobacillus · Protein structure · Review · Structure activity relation · Administration, Oral · Animals · Antigens · Bacterial Adhesion · Colony Count, Microbial · Drug Delivery Systems · Gene Expression Regulation, Bacterial · Genetic Engineering · Humans · Intestinal Mucosa · Lactobacillus · Lactococcus · Mice · Vaccines · Bacteria (microorganisms) · Lactobacillus · Posibacteria
[Abstract]

3 The production of antibody fragments and antibody fusion proteins by yeasts and filamentous fungi
article 2003    
Author: Joosten, V. · Lokman, C. · Hondel, C.A.M.J.J. van den · Punt, P.J.
Keywords: Biology · Biotechnology · cancer antibody · cell antibody · fungus antibody · hybrid protein · immunoglobulin · immunoglobulin F(ab) fragment · immunoglobulin Fc fragment · immunoglobulin heavy chain · immunoglobulin light chain · intrabody · recombinant antibody · single chain fragment variable antibody · unclassified drug · antibody combining site · antibody production · antigen binding · Aspergillus awamori · Candida boidinii · clinical trial · drug clearance · drug delivery system · Escherichia coli · eukaryote · gene expression system · Hansenula polymorpha · human · immunotherapy · Kluyveromyces · methylotrophic bacterium · mycology · nonhuman · Pichia · Pichia methanolica · Pichia pastoris · protein protein interaction · protein synthesis · review · Saccharomyces cerevisiae · Schizosaccharomyces pombe · Trichoderma reesei · Yarrowia lipolytica · Eukaryota · Fungi
[Abstract]

4 Local lentiviral short hairpin RNA silencing of CCR2 inhibits vein graft thickening in hypercholesterolemic apolipoprotein E3-Leiden mice
article 2009    
Author: Eefting, D. · Bot, I. · Vries, M.R. de · Schepers, A. · Bockel, J.H. van · Berkel, T.J.C. van · Biessen, E.A.L. · Quax, P.H.A.
Keywords: Biology · Biomedical Research · apolipoprotein E3 · chemokine receptor CCR2 · lentiviral short hairpin RNA · lentivirus vector · messenger RNA · monocyte chemotactic protein 1 · unclassified drug · animal cell · animal model · article · atherosclerosis · carotid artery · cell migration · cell proliferation · clinical feature · controlled study · disease course · drug delivery system · drug efficacy · drug targeting · gene silencing · gene therapy · hypercholesterolemia · in vitro study · in vivo study · infection · Lentivirinae · male · morphometrics · mouse · nonhuman · priority journal · protein expression · receptor upregulation · smooth muscle fiber · treatment outcome · vein graft · vein graft disease · vein surgery · viral gene delivery system · Animals · Apolipoprotein E3 · Atherosclerosis · Chemokine CCL2 · Disease Models, Animal · Graft Occlusion, Vascular · Hypercholesterolemia · Lentivirus · Male · Mice · Receptors, CCR2 · RNA Interference · Veins
[Abstract]

5 Transdermal administration of radiolabelled [14C]rotigotine by a patch formulation: A mass balance trial
article 2007    
Author: Cawello, W. · Wolff, H.M. · Meuling, W.J.A. · Horstmann, R. · Braun, M.
Keywords: Biomedical Research · carbon 14 · dopamine receptor stimulating agent · rotigotine · silicone · adult · article · clinical trial · diarrhea · dizziness · drug absorption · drug clearance · drug delivery system · drug distribution · drug elimination · drug formulation · drug metabolism · drug penetration · drug release · drug structure · drug tolerability · fatigue · human · human experiment · isotope labeling · liquid chromatography · liquid scintillation counting · male · mass balance · normal human · phase 1 clinical trial · priority journal · radioactivity · single drug dose · tandem mass spectrometry · Administration, Cutaneous · Adolescent · Adult · Carbon Radioisotopes · Chromatography, Liquid · Dopamine Agonists · Humans · Male · Middle Aged · Tandem Mass Spectrometry · Tetrahydronaphthalenes · Thiophenes
[Abstract]

6 A dynamic artificial gastrointestinal system for studying the behavior of orally administered drug dosage forms under various physiological conditions
article 2004    
Author: Blanquet, S. · Zeijdner, E. · Beyssac, E. · Meunier, J.-P. · Denis, S. · Havenaar, R. · Alric, M.
Keywords: Pharmacology Biology · Physiological Sciences · Dissolution profile · Gastrointestinal model · Oral formulations · Paracetamol · Probiotics · bacilor · bile salt · pancreatin · paracetamol · pepsin A · probiotic agent · starch · triacylglycerol lipase · unclassified drug · article · bacterial survival · bile secretion · body temperature · computer simulation · drug absorption · drug delivery system · drug dosage form · drug formulation · drug solubility · food intake · gastrointestinal tract · gastrointestinal transit · in vitro study · Lactobacillus casei · pancreas secretion · peristalsis · pH · priority journal · salivation · small intestine · stomach · stomach secretion · Acetaminophen · Administration, Oral · Digestive System · Dosage Forms · Gastrointestinal Transit · Models, Biological · Predictive Value of Tests
[Abstract]

7 Live bacterial delivery systems for development of mucosal vaccines
article 2000    
Author: Thole, J.E.R. · Dalen, P.J. van · Havenith, C.E.G. · Pouwels, P.H. · Seegers, J.F.M.L. · Tielen, F.D. · Zee, M.D. van der · Zegers, N.D. · Shaw, M.
Keywords: Nutrition · Attenuated bacteria · Commensal bacteria · Gene expression system · Mucosal immunity · Mucosal vaccines · Oral vaccines · Drug carrier · Recombinant vaccine · Vaccine · Antigen expression · Bacterium · Drug delivery system · Drug research · Gene expression system · Immune response · Lactic acid bacterium · Lactobacillus · Lactococcus lactis · Mucosa · Mycobacterium · Review · Salmonella · Staphylococcus carnosus · Streptococcus gordonii · Vibrio cholerae · Animals · Bacteria · BCG Vaccine · Drug Delivery Systems · Genetic Vectors · Humans · Immunity, Mucosal · Lactobacillus · Lactococcus lactis · Salmonella · Staphylococcus · Streptococcus · Vaccines, Attenuated · Vaccines, Synthetic · Vibrio cholerae · Animalia · Bacteria (microorganisms) · Lactobacillus mucosae · Lactococcus lactis · Mycobacterium · Salmonella · Staphylococcus carnosus · Streptococcus gordonii · Vibrio cholerae
[Abstract]

8 Human safety and pharmacokinetics of the CFC alternative propellants HFC 134a (1,1,1,2-tetrafluoroethane) and HFC 227 (1,1,1,2,3,3,3-heptafluoropropane) following whole-body exposure
article 2000    
Author: Emmen, H.H. · Hoogendijk, E.M.G. · Klöpping-Ketelaars, W.A.A. · Muijser, H. · Duistermaat, E. · Ravensberg, J.C. · Alexander, D.J. · Borkhataria, D. · Rusch, G.M. · Schmit, B.
Keywords: Nutrition · Apaflurane · Cfc 12 · Chlorofluorocarbon · Dichlorodifluoromethane · Hfc 227 · Norflurane · Unclassified drug · Adult · Aerosol · Blood pressure · Central nervous system disease · Clinical trial · Concentration response · Controlled clinical trial · Controlled study · Double blind procedure · Drug blood level · Drug delivery system · Drug elimination · Drug excretion · Drug safety · Electrocardiogram · Exposure · Female · Human · Human experiment · Lung function · Male · Metered dose inhaler · Normal human · Priority journal · Pulse rate · Respiratory tract disease · Sex difference · Steady state · Vapor · Administration, Inhalation · Adult · Aerosol Propellants · Atmosphere Exposure Chambers · Blood Pressure · Chlorofluorocarbons, Methane · Dose-Response Relationship, Drug · Double-Blind Method · Electrocardiography · Female · Half-Life · Humans · Hydrocarbons, Fluorinated · Inhalation Exposure · Male · Respiratory Function Tests · Safety · Sex Characteristics
[Abstract]

9 Tumor necrosis factor-α plays an important role in restenosis development
article 2005    
Author: Monraats, P.S. · Pires, N.M.M. · Schepers, A. · Agema, W.R.P. · Boesten, L.S.M. · Vries, M.R. de · Zwinderman, A.H. · Maat, M.P.M. de · Doevendans, P.A.F.M. · Winter, R.J. de · Tio, R.A. · Waltenberger, J. · Hart, L.M. 't · Frants, R.R. · Quax, P.H.A. · Vlijmen, B.J.M. van · Havekes, L.M. · Laarse, A. van der · Wall, E.E. van der · Jukema, J.W.
Keywords: Biology Health · Biomedical Research · Haplotype · TNFα · Transgenic mice · Apolipoprotein E3 · Messenger RNA · Thalidomide · Tumor necrosis factor alpha · Adult · Aged · Angiography · Animal experiment · Animal model · Clinical practice · Disease marker · Drug delivery system · Genetic polymorphism · Heredity · Knockout mouse · Nonhuman · Percutaneous coronary intervention · Restenosis · Risk assessment · Screening · Aged · Alleles · Angina Pectoris · Angiography · Angioplasty, Transluminal, Percutaneous Coronary · Animals · Constriction, Pathologic · Coronary Angiography · Coronary Disease · Coronary Restenosis · Disease Models, Animal · Female · Femoral Artery · Gene Expression Regulation, Neoplastic · Genetic Predisposition to Disease · Genotype · Haplotypes · Humans · Inflammation · Ischemia · Linkage Disequilibrium · Male · Mice · Mice, Knockout · Mice, Transgenic · Middle Aged · Multivariate Analysis · Odds Ratio · Polymorphism, Genetic · Regression Analysis · Reverse Transcriptase Polymerase Chain Reaction · Risk Factors · RNA, Messenger · Thalidomide · Treatment Outcome · Tumor Necrosis Factor-alpha · Up-Regulation · Animalia · Mus musculus
[Abstract]

10 Local perivascular delivery of anti-restenotic agents from a drug-eluting poly(ε-caprolactone) stent cuff
article 2005    
Author: Pires, N.M.M. · Hoeven, B.L. van der · Vries, M.R. de · Havekes, L.M. · Vlijmen, B.J. van · Hennink, W.E. · Quax, P.H.A. · Jukema, J.W.
Keywords: Biology · Biomedical Research · Animal model · Controlled drug release · Drug-eluting stents · Local delivery · Poly(ε-caprolactone) · Restenosis · Cardiology · Cell culture · Mathematical models · Muscle · Anti-restenotic agents · Contralateral femoral arteries · Drug-eluting stents (DES) · Interventional cardiology · Controlled drug delivery · Actin · Macrogol 300 · Macrogol derivative · Paclitaxel · Polycaprolactone · Polymer · Rapamycin · Unclassified drug · Animal experiment · Animal tissue · Artery intima proliferation · controlled study · Dose response · Drug delivery system · Drug formulation · Femoral artery · In vivo study · In-stent restenosis · Mouse · Nonhuman · Reproducibility · Smooth muscle fiber · Sustained drug release · Animals · Blood Vessel Prosthesis · Coated Materials, Biocompatible · Diffusion · Drug Carriers · Drug Implants · Femoral Artery · Graft Occlusion, Vascular · Immunosuppressive Agents · Male · Materials Testing · Mice · Mice, Inbred C57BL · Paclitaxel · Polyesters · Sirolimus · Stents · Animalia
[Abstract]

11 Activation of nuclear receptor Nur77 by 6-mercaptopurine protects against neointima formation
article 2007    
Author: Pires, N.M.M. · Pols, T.W.H. · Vries, M.R. de · Tiel, C.M.van · Bonta, P.I. · Vos, M. · Arkenbout, E.K. · Pannekoek, H. · Jukema, J.W. · Quax, P.H.A. · Vries, C.J.M. de
Keywords: Biology · Biomedical Research · Muscle, smooth · Receptors, cytoplasmic and nuclear · Restenosis · Stents · Transcription factors · cyclin dependent kinase inhibitor 1B · cycline · mercaptopurine · messenger RNA · nuclear receptor Nur77 · polycaprolactone · small interfering RNA · staurosporine · thymidine · tritium · animal experiment · animal model · animal tissue · antiangiogenic activity · antigen expression · apoptosis · artery intima proliferation · article · blood vessel injury · blood vessel wall · cell culture · cell cycle arrest · cell proliferation · controlled study · DNA synthesis · drug delivery system · drug dose comparison · drug effect · elution · experimental model · femoral artery · gene overexpression · human · human cell · hypothesis · in-stent restenosis · inflammation · intima · local therapy · male · mouse · nonhuman · observation · priority journal · protein expression · receptor down regulation · receptor upregulation · smooth muscle fiber · sustained drug release · transgenic mouse · vascular smooth muscle · wild type · 6-Mercaptopurine · Animals · Antimetabolites, Antineoplastic · Apoptosis · Cell Division · Cells, Cultured · Coronary Restenosis · Disease Models, Animal · DNA-Binding Proteins · Drug Implants · Femoral Artery · Humans · Male · Mice · Mice, Inbred Strains · Mice, Transgenic · Muscle, Smooth, Vascular · Receptors, Cytoplasmic and Nuclear · Receptors, Steroid · RNA, Messenger · RNA, Small Interfering · Transcription Factors · Tunica Intima · Umbilical Arteries
[PDF] [Abstract]

Search results also available in MS Excel format.

Showing 1 to 11 of 11 found. | Sort by date