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1 Eye irritation testing: The way forward : the report and recommendations of ECVAM workshop 34
article 1999    
Author: Balls, M. · Berg, N. · Bruner, L.H. · Curren, R.D. · Silva, O. de · Earl, L.K. · Esdaile, D.J. · Fentem, J.H. · Liebsch, M. · Ohno, Y. · Prinsen, M.K. · Spielmann, H. · Worth, A.P.
Keywords: Nutrition · Animal welfare · Conference paper · Drug research · Eye irritation · Good laboratory practice · Nonhuman · Practice guideline · Priority journal · Animalia

2 Lost in translation? Role of metabolomics in solving translational problems in drug discovery and development
article 2006    
Author: Greef, J. van der · Adourian, A. · Muntendam, P. · McBurney, R.N.
Keywords: Biology · Analytical research · biological marker · drug metabolite · new drug · bioinformatics · body fluid · data base · decision making · drug determination · drug efficacy · drug marketing · drug research · drug safety · human · medical technology · metabolomics · multiple sclerosis · non insulin dependent diabetes mellitus · nonhuman · osteoarthritis · phenotype · postmarketing surveillance · proteomics · review · serology · structure activity relation
[Abstract]

3 Nonclinical testing of vaccines: Report from a workshop
article 2009    
Author: Laan, J.W. van der · Forster, R. · Ledwith, B. · Gruber, M. · Gould, S. · Segal, L. · Penninks, A.
Keywords: Health · Adjuvants · Developmental and reproductive toxicology · DNA vaccines · Nonclinical evaluation · Safety testing · Therapeutic vaccines · Vaccines · diphtheria pertussis tetanus vaccine · DNA vaccine · immunological adjuvant · immunomodulating agent · live vaccine · Meningococcus vaccine · pertussis vaccine · vaccine · Wart virus vaccine · conference paper · disease model · drug dose regimen · drug efficacy · drug research · drug safety · drug screening · drug tolerability · electroporation · human · immune response · immunogenicity · male fertility · nonhuman · pharmacodynamics · practice guideline · priority journal · reproductive toxicity · tattooing · toxicity testing · toxicology · vaccination · workshop
[Abstract]

4 Systems biology, connectivity and the future of medicine
article 2005    
Author: Greef, J. van der
Keywords: Biology · Analytical research · Disease progression · Disease system fingerprints · Diseases · Drug perturbations · Drugs · Medicine · Patient treatment · Reversed-pharmacology · Systems biology · Systems pathology · Systems pharmacology · Systems-based combinatorial-therapies approach · Biology · Diseases · Drug therapy · Pathology · Pharmacokinetics · Disease system fingerprints · Pharmacology · Systems biology · Drug products · amlodipine plus atorvastatin · berberine · biological marker · fluticasone propionate plus salmeterol · ginseng extract · glibenclamide plus metformin · article · asthma · bioinformatics · biostatistics · cardiovascular disease · clinical protocol · disease course · drug design · drug industry · drug research · human · hypercholesterolemia · in vivo study · medicine · metabolic syndrome X · methodology · molecular biology · non insulin dependent diabetes mellitus · nonhuman · quality control · quality of life · Cell Physiology · Drug Design · Models, Biological · Pharmaceutical Preparations · Pharmacology · Pharmacology, Clinical · Systems Biology · Panax ginseng
[Abstract]

5 Live bacterial delivery systems for development of mucosal vaccines
article 2000    
Author: Thole, J.E.R. · Dalen, P.J. van · Havenith, C.E.G. · Pouwels, P.H. · Seegers, J.F.M.L. · Tielen, F.D. · Zee, M.D. van der · Zegers, N.D. · Shaw, M.
Keywords: Nutrition · Attenuated bacteria · Commensal bacteria · Gene expression system · Mucosal immunity · Mucosal vaccines · Oral vaccines · Drug carrier · Recombinant vaccine · Vaccine · Antigen expression · Bacterium · Drug delivery system · Drug research · Gene expression system · Immune response · Lactic acid bacterium · Lactobacillus · Lactococcus lactis · Mucosa · Mycobacterium · Review · Salmonella · Staphylococcus carnosus · Streptococcus gordonii · Vibrio cholerae · Animals · Bacteria · BCG Vaccine · Drug Delivery Systems · Genetic Vectors · Humans · Immunity, Mucosal · Lactobacillus · Lactococcus lactis · Salmonella · Staphylococcus · Streptococcus · Vaccines, Attenuated · Vaccines, Synthetic · Vibrio cholerae · Animalia · Bacteria (microorganisms) · Lactobacillus mucosae · Lactococcus lactis · Mycobacterium · Salmonella · Staphylococcus carnosus · Streptococcus gordonii · Vibrio cholerae
[Abstract]

6 Rescuing drug discovery: In vivo systems pathology and systems pharmacology
article 2005    
Author: Greef, J. van der · McBurney, R.N.
Keywords: Pharmacology Health · Analytical research · 5' methoxyhydnocarpin · berberine · biological marker · ginseng extract · herbaceous agent · Hypericum extract · paroxetine · unclassified drug · article · bioinformatics · cardiovascular disease · clinical trial · cost benefit analysis · cost control · cost effectiveness analysis · data base · depression · drug approval · drug design · drug efficacy · drug indication · drug industry · drug information · drug marketing · drug research · drug response · drug safety · drug screening · drug targeting · growth inhibition · health care · health care cost · health program · human · in vivo study · non insulin dependent diabetes mellitus · nonhuman · patient compliance · prediction · prescription · priority journal · productivity · quantitative analysis · standard · system analysis · validation process · animal · diagnosis · economics · mass communication · review · Animals · Cost-Benefit Analysis · Diagnosis · Diffusion of Innovation · Drug Approval · Drug Design · Drug Evaluation · Drug Evaluation, Preclinical · Drug Industry · Humans
[Abstract]

7 Food allergy: What do we learn from animal models?
article 2004    
Author: Knippels, L.M.J. · Wijk, F. van · Penninks, A.H.
Keywords: Health · Toxicology and Applied Pharmacology · Allergenicity · Animal models · Food allergy · Therapy · Ara h 1 allergen · Ara h 2 allergen · Ara h 3 allergen · DNA vaccine · food allergen · fungal immunomodulatory protein · fungal protein · immunoglobulin E antibody · protein fip fve · recombinant antigen · recombinant cytokine · recombinant peanut allergen · unclassified drug · allergenicity · antigen specificity · article · bacterium · clinical research · desensitization · dog · dose response · drug activity · drug mechanism · drug research · drug screening · food allergy · genetic susceptibility · health hazard · hypothesis · immunological tolerance · immunopathogenesis · immunoprophylaxis · mouse strain · nonhuman · pathophysiology · prediction · priority journal · protein degradation · protein diet · protein intake · protein structure · publication · rat strain · review · screening test · sensitization · swine · Th1 cell · Th2 cell · Animals · Food Hypersensitivity · Humans · Immunotherapy · Interleukin-10 · Interleukin-4 · Models, Animal · T-Lymphocytes
[Abstract]

8 Metabolomics in the context of systems biology: Bridging Traditional Chinese Medicine and molecular pharmacology
article 2005    
Author: Wang, M. · Lamers, R.J.A.N. · Korthout, H.A.A.J. · Nesselrooij, J.H.J. van · Witkamp, R.F. · Heijden, R. van der · Voshol, P.J. · Havekes, L.M. · Verpoorte, R. · Greef, J. van der
Keywords: Health Pharmacology · Analytical research · Metabolomics · Systems biology · Traditional Chinese Medicine (TCM) · 5' methoxyhdnocarpin · Alanine aminotransferase · Alkaloid · Apolipoprotein E · Berberine · Biflavonoid · Bilobalide · Cannabidiol · Cannabis · Chaconine · Cholesterol · Flavonoid · Ginkgo biloba extract · Ginkgolide · Glucoside · Herbaceous agent · Insulin · Low density lipoprotein · Plant extract · Prodrug · Salicylic acid · Saligenin · Saponin · Solanine · Tetrahydrocannabinol · Triacylglycerol · Unclassified drug · Very low density lipoprotein · Alanine aminotransferase blood level · Animal experiment · Animal model · Atherosclerosis · Bark · Blood flow · Chinese medicine · Clinical pharmacology · Controlled study · Data analysis · DNA microarray · Drug effect · Drug efficacy · Drug potentiation · Drug research · Drug safety · Drug targeting · Female · Ginkgo biloba · Headache · Herbal medicine · High performance liquid chromatography · Human · Human experiment · Insulin resistance · Insulin sensitivity · Ion cyclotron resonance mass spectrometry · Lipid metabolism · Liver function · Male · Mass spectrometry · Medicinal plant · Metabolic syndrome X · Metabolite · Molecular pharmacology · Nonhuman · Nuclear magnetic resonance spectroscopy · Pain · Phytotherapy · Plant leaf · Proton nuclear magnetic resonance · Rat · Thin layer chromatography · Traditional medicine · Willow · Drugs, Chinese Herbal · Humans · Pharmacology · Phytotherapy
[Abstract]

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Showing 1 to 8 of 8 found. | Sort by date