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Showing 1 to 15 of 15 found. | Sort by date

1 Ritonavir protects against the development of atherosclerosis in APOE *3-Leiden mice
article 2010    
Author: Boer, M.A.M. den · Westerterp, M. · Vries-van der Weij, J. de · Wang, Y. · Hu, L. · Espirito Santo, S.M.S. · Kooistra, T. · Reiss, P. · Romijn, J.A. · Havekes, L.M. · Rensen, P.C.N.
Keywords: Biology · Biomedical Research · Cardiovascular disease · Dyslipidemia · High-density lipoprotein · Protease inhibitor
[Abstract]

2 Actions of metformin and statins on lipid and glucose metabolism and possible benefit of combination therapy
article 2018    
Author: Stee, M.F. van · Graaf, A.A. de · Groen, A.K.
Keywords: Biology · Atorvastatin · Combination therapy · Dyslipidemia · Glucose metabolism · Lipid metabolism · Metformin · Simvastatin · Type 2 diabetes
[PDF] [Abstract]

3 APOE*3Leiden.CETP transgenic mice as model for pharmaceutical treatment of the metabolic syndrome
article 2014    
Author: Hoek, A.M. van den · Hoorn, J.W.A. van der · Maas, A.C. · Hoogen, R.M. van den · Nieuwkoop, A. van · Droog, S. · Offerman, E.H. · Pieterman, E.J. · Havekes, L.M. · Princen, H.M.G.
Keywords: Biology · Diabetic dyslipidemia · Insulin resistance · NAFLD · Obesity · Pharmacological treatment · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · ELSS - Earth, Life and Social Sciences
[Abstract]

4 The contribution of metabolic and adipose tissue inflammation to non-alcoholic fatty liver disease
dissertation 2017    
Author: Mulder, P.C.A.
Keywords: Biology · NAFLD/NASH · Obesity · Adipose tissue · Adipokines · Inflammation · Insulin resistance · Dyslipidemia · Atherosclerosis · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · ELSS - Earth, Life and Social Sciences
[PDF] [Abstract]

5 Role of metabolic overload and metabolic inflammation in the development of Nonalcoholic Steatohepatitis (NASH)
dissertation 2015    
Author: Liang, W.
Keywords: Health · Metabolic syndromes · Fatty liver · Insulin resistance · Dyslipidemia · Fibrosis · NAFLD/NASH · Histology · Pathogensis · Factors · Chronic inflammation · Transcription factors · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · ELSS - Earth, Life and Social Sciences
[PDF] [Abstract]

6 Cholesteryl ester transfer protein inhibition: Effect on reverse cholesterol transport?
article 2006    
Author: Rensen, P.C.N. · Havekes, L.M.
Keywords: Biology · Biomedical Research · 2 methylpropanethioic acid s [2 [1 (2 ethylbutyl)cyclohexylcarboxamido]phenyl] ester · Atorvastatin · Cholesterol ester transfer protein inhibitor · Fibric acid derivative · High density lipoprotein cholesterol · Hydroxymethylglutaryl coenzyme A reductase inhibitor · Nicotinic acid · Torcetrapib · Atherosclerosis · Cholesterol transport · Clinical trial · Drug efficacy · Drug mechanism · Dyslipidemia · Editorial · Ischemic heart disease · Nonhuman · Plasma clearance · Protein expression · Reverse cholesterol transport · Animals · Biological Transport · Cardiovascular Diseases · Carrier Proteins · Cholesterol Ester Transfer Proteins · Cholesterol Esters · Cholesterol, HDL · Glycoproteins · Humans · Lipid Metabolism · Lipoproteins, HDL · Rabbits · Risk Factors
[Abstract]

7 Inhibition of the central melanocortin system decreases brown adipose tissue activity
article 2014    
Author: Kooijman, S. · Boon, M.R. · Parlevliet, E.T. · Geerling, J.J. · Pol, V. van de · Romijn, J.A. · Havekes, L.M. · Meurs, I. · Rensen, P.C.N.
Keywords: Biology · Energy expenditure · Liver · Triglycerides · Very low density lipoprotein · White adipose tissue · Apolipoprotein E · Fat droplet · Melanocortin · Melanocortin 3 receptor · Melanocortin 4 receptor · N acetyl alpha intermedin[4-10]cyclo[4 norleucine 5 aspartic acid 7 [3 (2 naphthyl)alanine] 10 lysinamide] · Triacylglycerol · Uncoupling protein 1 · Animal experiment · Animal tissue · Body fat · Brown adipose tissue · Central melanocortin system · Controlled study · Dyslipidemia · Endocrine system · Fat mass · Fatty liver · Female · Food intake · Hormone inhibition · Lipid analysis · Lipid oxidation · Lipid storage · Mouse · Nonhuman · Obesity · Signal transduction · Weight gain · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · ELSS - Earth, Life and Social Sciences
[PDF] [Abstract]

8 Dexamethasone-eluting stents for the prevention of in-stent restenosis: Evidence for a differential effect in insulin-dependent and non-insulin-dependent diabetic patients
article 2008    
Author: Hoeven, B.L. van der · Pires, N.M.M. · Warda, H.M. · Putter, H. · Quax, P.H.A. · Schalij, M.J. · Jukema, J.W.
Keywords: Health · Dexamethasone · Diabetes mellitus · Restenosis · dexamethasone · adult · aged · angiography · article · clinical article · drug eluting stent · dyslipidemia · female · follow up · heart infarction · human · hypertension · insulin dependent diabetes mellitus · male · non insulin dependent diabetes mellitus · priority journal · restenosis · revascularization · smoking · survival · Adolescent · Adult · Aged · Angioplasty, Transluminal, Percutaneous Coronary · Cohort Studies · Coronary Angiography · Coronary Restenosis · Coronary Stenosis · Dexamethasone · Diabetes Mellitus, Type 1 · Diabetes Mellitus, Type 2 · Diabetic Angiopathies · Drug-Eluting Stents · Female · Follow-Up Studies · Humans · Male · Middle Aged · Probability · Risk Assessment · Survival Rate · Treatment Outcome · Ultrasonography, Interventional
[Abstract]

9 Peripheral cannabinoid 1 receptor blockade activates brown adipose tissue and diminishes dyslipidemia and obesity
article 2014    
Author: Boon, M.R. · Kooijman, S. · Dam, A.D. van · Pelgrom, L.R. · Berbée, J.F.P. · Visseren, C.A.R. · Aggele, R.C. van · Hoek, A.M. van den · Sips, H.C.M. · Lombès, M. · Havekes, L.M. · Tamsma, J.T. · Guigas, B. · Meijer, O.C. · Jukema, J.W. · Rensen, P.C.N.
Keywords: Biology · Rimonabant · Sympathetic nervous system · Uncoupling protein 1 · Adrenergic receptor · Am 6545 · Cannabinoid 1 receptor · Cannabinoid 1 receptor antagonist · Cyclic AMP · Fat droplet · Lipoprotein · Triacylglycerol · Unclassified drug · Adrenergic system · Animal experiment · Animal model · Animal tissue · Appetite · Brown adipocyte · Alorimetry · Controlled study · Diet induced obesity · Dyslipidemia · Energy expenditure · Energy metabolism · Food intake · In vitro study · In vivo study · Lipid analysis · Lipid storage · Lipolysis · Lipoprotein metabolism · Male · Mouse · Nonhuman · Oxygen consumption · Physical activity · Thermogenesis · Triacylglycerol blood level · Weight change · Weight reduction · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · ELSS - Earth, Life and Social Sciences
[Abstract]

10 Replacement of Dietary Saturated Fat by PUFA-Rich Pumpkin Seed Oil Attenuates Non-Alcoholic Fatty Liver Disease and Atherosclerosis Development, with Additional Health Effects of Virgin over Refined Oil
article 2015    
Author: Mulder, P. · Stavro, P.M. · Manuel Suárez, M. · Arola-Arnal, A. · Duyvenvoorde, W. van · Kooistra, T. · Wielinga, P.Y. · Kleemann, R.
Keywords: Biology · Amyloid A protein · Mouse · Nonhuman · Tisk factor amyloid A protein · Cell adhesion molecule · Low density lipoprotein cholesterol · Polyunsaturated fatty acid · Refined pumpkin seed oil · Saturated fatty acid · Theobroma oil · Triacylglycerol · Unclassified drug · Unsaturated fatty acid · Vegetable oil · Virgin pumpkin seed oil · Animal cell · Animal experiment · Animal model · Animal tissue · Antiinflammatory activity · Atherosclerosis · Controlled study · Disease association · Disease severity · Dyslipidemia · Fat intake · Female · Inflammation · Lipid composition · Lipid metabolism · Nonalcoholic fatty liver · Phytochemistry · Risk assessment · Risk factor · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · ELSS - Earth, Life and Social Sciences
[PDF] [Abstract]

11 Salsalate attenuates diet induced non-alcoholic steatohepatitis in mice by decreasing lipogenic and inflammatory processes
article 2015    
Author: Liang, W. · Verschuren, L. · Mulder, P. · Hoorn, J.W.A. van der · Verheij, J. · Dam, A.D. van · Boon, M.R. · Princen, H.M.G. · Havekes, L.M. · Kleemann, R. · Hoek, A.M. van den
Keywords: Biology · Alanine aminotransferase · Aspartate aminotransferase · Glucose · High density lipoprotein cholesterol · Insulin · Interleukin 6 · Low density lipoprotein cholesterol · Peroxisome proliferator activated receptor alpha · Salsalate · Triacylglycerol · Alanine aminotransferase blood level · Animal cell · Animal experiment · Animal model · Animal tissue · Aspartate aminotransferase blood level · Body weight · Controlled study · Down regulation · Drug efficacy · Drug response · Dyslipidemia · Energy metabolism · Fatty acid oxidation · Fatty liver · Gene expression · Glucose blood level · Glycemic control · Hepatitis · Insulin blood level · Insulin resistance · Lipid metabolism · Lipogenesis · Male · Mouse · Nonalcoholic fatty liver · Nonhuman · Treatment duration · Treatment outcome · Triacylglycerol blood level · Upregulation · Weight gain · Biomedical Innovation · Healthy Living · Life · MSB - Microbiology and Systems Biology MHR - Metabolic Health Research · ELSS - Earth, Life and Social Sciences
[Abstract]

12 Hepatic Steatosis: A Mediator of the Metabolic Syndrome. Lessons from Animal Models
article 2004    
Author: Boer, M. den · Voshol, P.J. · Kuipers, F. · Havekes, L.M. · Romijn, J.A.
Keywords: Biology · Biomedical Research · Fatty acid metabolism · Glucose metabolism · Insulin resistance · Lipoprotein metabolism · Mouse models · Alcohol · Triacylglycerol · Animal experiment · Animal model · Disease association · Dyslipidemia · Endocrine system · Genetic transcription · Glucose metabolism · Lnsulin resistance · Lipid liver level · Metabolic syndrome X · Mouse · Non insulin dependent diabetes mellitus · Nonhuman · Partition coefficient · Pathophysiology · Rodent · Short survey · Adipose Tissue · Animals · Diabetes Mellitus, Type 2 · Dogs · Fatty Acids · Fatty Liver · Glucose · Homeostasis · Humans · Hyperlipidemias · Insulin Resistance · Liver · Metabolic Syndrome X · Mice · Models, Animal · Models, Biological · Obesity · Rats · Rats, Zucker · Transcription, Genetic · Triglycerides
[Abstract]

13 The impact of metabolic syndrome and CRP on vascular phenotype in type 2 diabetes mellitus
article 2008    
Author: Alizadeh Dehnavi, R. · Beishuizen, E.D. · Ree, M.A. van de · Le Cessie, S. · Huisman, M.V. · Kluft, C. · Princen, H.M.G. · Tamsma, J.T.
Keywords: Health · C-reactive protein · Diabetes mellitus type 2 · Endothelial function · Intima media thickness · Metabolic syndrome · PAI-1 · C reactive protein · endothelial leukocyte adhesion molecule 1 · fibrinogen · high density lipoprotein · plasminogen activator inhibitor 1 · thrombomodulin · tissue plasminogen activator · vascular cell adhesion molecule 1 · von Willebrand factor · adult · aged · arterial wall thickness · article · atherosclerosis · cholesterol blood level · diastolic blood pressure · dyslipidemia · female · human · kidney function · major clinical study · male · metabolic syndrome X · non insulin dependent diabetes mellitus · phenotype · risk factor · sex difference · systolic blood pressure · Aged · Biological Markers · C-Reactive Protein · Diabetes Mellitus, Type 2 · E-Selectin · Female · Fibrinogen · Humans · Inflammation · Male · Metabolic Syndrome X · Middle Aged · Phenotype · Plasminogen Activator Inhibitor 1 · Thrombomodulin · Tissue Plasminogen Activator · Tunica Intima · Tunica Media · Vascular Cell Adhesion Molecule-1 · von Willebrand Factor
[Abstract]

14 No effects of atorvastatin (10 mg/d or 80 mg/d) on nitric oxide, prostacyclin, thromboxane and oxidative stress in type 2 diabetes mellitus patients of the DALI study
article 2015    
Author: Tsikas, D. · Pham, V.V. · Suchy, M.T. · Ree, M.A. van de · Huisman, M.V. · Frölich, J.C. · Princen, H.M.G.
Keywords: Biology · 8-iso-Prostaglandin F2α · Carbonic anhydrase · Cardiovascular disease · Diabetes mellitus type 2 · Nitric oxide · Oxidative stress · Prostacyclin · Statins · Thromboxane · 2,3 dinor 6 oxoprostaglandin F1 alpha · 2,3 dinorthromboxane B2 · 8 isoprostaglandin F2 alpha · Atorvastatin · Carbonate dehydratase · Cholesterol · Nitrate · Nitric oxide · Nitrite · Placebo · Prostacyclin · Prostaglandin synthase · Thromboxane · Thromboxane A2 · Adult · Aged · Antioxidant activity · Biosynthesis · Cholesterol metabolism · Controlled study · Dose response · Double blind procedure · Drug effect · Drug treatment failure · Dyslipidemia · Female · Heart protection · Lipid peroxidation · Lipolysis · Major clinical study · Male · Mass fragmentography · Middle aged · Non insulin dependent diabetes mellitus · Oxidative stress · Randomized controlled trial · Tandem mass spectrometry · Treatment duration · Urine level · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · ELSS - Earth, Life and Social Sciences
[Abstract]

15 Ritonavir impairs lipoprotein lipase-mediated lipolysis and decreases uptake of fatty acids in adipose tissue
article 2006    
Author: Boer, M.A.M. den · Berbée, J.F.P. · Reiss, P. · Valk, M. van der · Voshol, P.J. · Kuipers, F. · Havekes, L.M. · Rensen, P.C.N. · Romijn, J.A.
Keywords: Dyslipidemia · FA metabolism · Protease inhibitor · TG metabolism · Transgenic mice · Albumin · Lipoprotein lipase · Proteinase inhibitor · Ritonavir · Triacylglycerol · Triolein · Very low density lipoprotein · Anticoagulant agent · Apolipoprotein E · Apolipoprotein E3 (Leidein) · Diagnostic agent · Fatty acid · Heparin · Tritium · Very low density lipoprotein cholesterol · Adipose tissue · Animal tissue · Clearance · Controlled study · Drug mechanism · Emulsion · Enzyme activity · Fat intake · Fatty acid metabolism · Fatty acid transport · Half life time · Hypertriglyceridemia · Lipid diet · Lipodystrophy · Lipolysis · Mouse · Nonhuman · Postprandial state · Transgenic mouse · Triacylglycerol blood level · Biosynthesis · Blood · Chemically induced disorder · Drug effect · Enzyme activation · Genetics · Human immunodeficiency virus infection · Metabolism · Adipose Tissue · Animals · Anticoagulants · Apolipoprotein E3 · Apolipoproteins E · Cholesterol, VLDL · Emulsions · Enzyme Activation · Fatty Acids · Female · Heparin · HIV Infections · HIV Protease Inhibitors · Hypertriglyceridemia · Lipolysis · Lipoprotein Lipase · Mice · Mice, Transgenic · Postprandial Period · Ritonavir · Triglycerides · Triolein · Tritium
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 15 of 15 found. | Sort by date