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1 The metabolic activity of fecal microbiota from healthy individuals and patients with inflammatory bowel disease
article 2004    
Author: Nuenen, M.H.M.C. van · Venema, K. · Woude, J.C.J. van der · Kuipers, E.J.
Keywords: Nutrition · Physiological Sciences · Fermentation · In vitro model · Inflammatory bowel disease · Metabolites · Microbial activity · ammonia · branched chain fatty acid · fatty acid · lactic acid · phenol derivative · short chain fatty acid · unclassified drug · adult · article · carbohydrate metabolism · chronicity · clinical article · controlled study · enteritis · fatty acid synthesis · feces microflora · fermentation · human · in vitro study · metabolite · microbial metabolism · model · nonhuman · normal human · priority journal · protein degradation · Adult · Ammonia · Bacteria · Colitis, Ulcerative · Colon · Crohn Disease · Fatty Acids · Fatty Acids, Volatile · Feces · Fermentation · Humans · Lactic Acid · Middle Aged
[Abstract]

2 The influence of microbial metabolites on human intestinal epithelial cells and macrophages in vitro
article 2005    
Author: Nuenen, M.H.M.C. van · Ligt, R.A.F. de · Doornbos, R.P. · Woude, J.C.J. van der · Kuipers, E.J. · Venema, K.
Keywords: Nutrition · Physiological Sciences · Interleukin-10 · Intestinal epithelial cells · Macrophages · Microbial metabolites · Tumour necrosis factor-α · ammonia · butyric acid · cytokine · interleukin 10 · tumor necrosis factor alpha · valeric acid · article · cell strain CACO 2 · concentration (parameters) · cytokine release · electric resistance · enteritis · epithelium cell · human · human cell · immunity · macrophage · metabolism · metabolite · physiology · priority journal · Ammonium Chloride · Butyrates · Caco-2 Cells · Epithelial Cells · Humans · Immunity, Mucosal · Inflammatory Bowel Diseases · Interleukin-10 · Intestines · Macrophages · Pentanoic Acids · Tumor Necrosis Factor-alpha · U937 Cells
[Abstract]

3 Cost-effectiveness of pharmacogenomics in clinical practice: A case study of thiopurine methyltransferase genotyping in acute lymphoblastic leukemia in Europe
article 2006    
Author: Akker-van Marle, M.E. van den · Gurwitz, D. · Detmar, S.B. · Enzing, C.M. · Hopkins, M.M. · Gutierrez De Mesa, E. · Ibarreta, D.
Keywords: Health · Antineoplastic Agents · Cost-Benefit Analysis · Europe · Genotype · Humans · Leukemia, Lymphocytic, Acute · Methyltransferases · Models, Economic · Pharmacogenetics · 6-mercaptopurine · Acute lymphoblastic leukemia · Adverse drug reactions · Cost-effectiveness analysis · Drug-metabolizing enzymes · Germany · Ireland · Netherlands · Pharmacogenetics · Thiopurine drugs · Thiopurine methyltransferase (TMPT) · United Kingdom · Azathioprine · Drug metabolizing enzyme · Mercaptopurine · Thiopurine methyltransferase · Acute lymphoblastic leukemia · Anorexia · Blood toxicity · Bone marrow suppression · Calculation · Case study · Clinical practice · Cytopenia · Diarrhea · Drug dose regimen · Drug fatality · Drug hypersensitivity · Enteritis · Enzyme activity · Enzyme deficiency · Europe · Graft rejection · Health care quality · Health survey · Heterozygosity · Homozygosity · Hospital cost · Infection · Interview · Leukopenia · Nausea · Pancreatitis · Phenotype · Polymerase chain reaction · Sensitivity and specificity · Sepsis · United Kingdom · Vomiting · Wild type
[Abstract]

4 Gene expression profiling identifies mechanisms of protection to recurrent trinitrobenzene sulfonic acid colitis mediated by probiotics
article 2012    
Author: Mariman, R. · Kremer, S.H.A. · Erk, M. van · Lagerweij, T. · Koning, F. · Nagelkerken, L.
Keywords: Biology · genome wide screening · immune modulation · probiotic bacteria · TNBS colitis · alpha defensin · carboxypeptidase A · CD11b antigen · chymase · gamma interferon · granulocyte colony stimulating factor · granulocyte macrophage colony stimulating factor · interleukin 10 · interleukin 17 · interleukin 1alpha · interleukin 1beta · interleukin 3 · interleukin 9 · macrophage inflammatory protein 1alpha · monocyte chemotactic protein 1 · polypeptide antibiotic agent · probiotic agent · trinitrobenzenesulfonic acid · abscess · adaptive immunity · animal experiment · animal model · animal tissue · article · CD4 CD8 ratio · CD4+ T lymphocyte · CD8+ T lymphocyte · cell activity · cell infiltration · chronic inflammation · colitis · colon mucosa · controlled study · drug efficacy · enteritis · female · gene expression · goblet cell · histopathology · immunocompetent cell · inflammatory cell · intestine mucosa · Lactobacillus plantarum · long term care · mast cell · microarray analysis · mouse · nonhuman · priority journal · upregulation · weight reduction · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research MSB - Microbiology and Systems Biology · EELS - Earth, Environmental and Life Sciences
[Abstract]

5 Effect of the anti-tumor necrosis factor-α antibody infliximab on the ex vivo mucosal matrix metalloproteinase-proteolytic phenotype in inflammatory bowel disease
article 2007    
Author: Meijer, M.J. · Mieremet-Ooms, M.A.C. · Duijn, W. van · Zon, A.M. van der · Hanemaaijer, R. · Verheijen, J.H. · Hogezand, R.A. van · Lamers, C.B.H.W. · Verspaget, H.W.
Keywords: Biomedical Research · Inflammatory bowel disease · Infliximab · Matrix metalloproteinase · Tissue inhibitor of metalloproteinase · Tumor necrosis factor-alpha · azathioprine · cyclosporin · gelatinase A · gelatinase B · infliximab · interstitial collagenase · mesalazine · messenger RNA · pokeweed mitogen · steroid · stromelysin · tissue inhibitor of metalloproteinase 1 · tissue inhibitor of metalloproteinase 2 · tumor necrosis factor alpha antibody · adolescent · adult · aged · article · clinical article · controlled study · Crohn disease · drug effect · enteritis · explant · female · genotype · human · human tissue · intestine mucosa · male · priority journal · protein degradation · protein expression · single nucleotide polymorphism · ulcerative colitis · Adolescent · Adult · Aged · Antibodies, Monoclonal · Colitis, Ulcerative · Crohn Disease · Down-Regulation · Female · Humans · Intestinal Mucosa · Male · Matrix Metalloproteinases · Middle Aged · Phenotype · Polymorphism, Single Nucleotide · Reverse Transcriptase Polymerase Chain Reaction · Tissue Culture Techniques · Tissue Inhibitor of Metalloproteinases · Tumor Necrosis Factor-alpha
[Abstract]

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Showing 1 to 5 of 5 found. | Sort by date