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1 Reduced Tonicity Stimulates an Inflammatory Response in Nucleus Pulposus Tissue That Can Be Limited by a COX-2-Specific Inhibitor
article 2015    
Author: Dijk, B. van · Potier, E. · Dijk, M. van · Langelaan, M. · Papen-Botterhuis, N.E. · Ito, K.
Keywords: Health · Explant culture · Disc herniation · Inflammation · Regenerative therapy · Sustained release · Healthy Living · Nano Technology · MAS - Materials Solutions · TS - Technical Sciences
[Abstract]

2 Skin irritants and contact sensitizers induce Langerhans cell migration and maturation at irritant concentration
article 2006    
Author: Jacobs, J.J.L. · Lehé, C.L. · Hasegawa, H. · Elliott, G.R. · Das, P.K.
Keywords: Contact allergy · Langerhans cell · Maturation · Migration · Skin irritation · CD83 antigen · Chemokine receptor CCR7 · Contact allergen · Irritant agent · T6 antigen · Article · Cell count · Cell maturation · Cell migration · Contact allergy · Contact sensitization · Controlled study · Dendritic cell · Explant · Human · Human tissue · Hypersensitivity reaction · Immunohistochemistry · Immunopathology · Langerhans cell · Lymph node · Quantitative analysis · Skin allergy · Skin culture · Skin irritation · Allergens · Cell Differentiation · Cell Movement · Dermatitis, Contact · Dermatitis, Occupational · Female · Humans · Irritants · Langerhans Cells · Lymph Nodes · Skin · Skin Irritancy Tests · Tissue Culture Techniques
[Abstract]

3 Subtoxic concentrations of allergenic haptens induce LC migration and maturation in a human organotypic skin explant culture model: A novel method for identifying potential contact allergens
article 2006    
Author: Lehé, C.L. · Jacobs, J.J.L. · Hua, C.M. · Courtellemont, P. · Elliott, G.R. · Das, P.K.
Keywords: Activation markers · Allergen · HOSEC · Langerhans cell · Migration · CD83 antigen · Contact allergen · Hapten · HLA DR antigen · Irritant agent · T6 antigen · Allergenicity · Antigen expression · Article · Cell maturation · Cell migration · Controlled study · Delayed hypersensitivity · Epidermis · Epidermis cell · Explant · Flow cytometry · Human · Human tissue · immunohistochemistry · Langerhans cell · Quantitative analysis · Skin biopsy · Skin culture · Upregulation · Allergens · Antigens, CD · Cell Differentiation · Cell Movement · Dermatitis, Allergic Contact · Haptens · Humans · Immunoglobulins · Langerhans Cells · Membrane Glycoproteins · Models, Biological · Skin · Tissue Culture Techniques
[Abstract]

4 Skin irritation and corrosion
article 2005    
Author: Zuang, V. · Alonso, M.A. · Botham, P.A. · Eskes, C. · Fentem, J. · Liebsch, M. · Sandt, J.J.M. van de
Keywords: Chemistry Safety · Food and Chemical Risk Analysis · cosmetic · acute toxicity · animal testing alternative · cell growth · cell viability · chemical structure · corrosion · electric resistance · explant · human · in vitro study · model · pH measurement · priority journal · reproducibility · review · safety · skin culture · skin irritation · skin water loss · standardization · toxicity testing · validation process · Animal Testing Alternatives · Animals · Cell Survival · Consumer Product Safety · Cosmetics · Endpoint Determination · European Union · Humans · Irritants · Organ Culture Techniques · Quantitative Structure-Activity Relationship · Skin · Skin Irritancy Tests · Swine · Animalia

5 Human granzyme B mediates cartilage proteoglycan degradation and is expressed at the invasive front of the synovium in rheumatoid arthritis
article 2001    
Author: Ronday, H.K. · Laan, W.H. van der · Tak, P.P. · Roos, J.A.D.M. de · Bank, R.A. · Tekoppele, J.M. · Froelich, C.J. · Hack, C.E. · Hogendoorn, P.C.W. · Breedveld, F.C. · Verheijen, J.H.
Keywords: Biology Health · Biomedical Research · Cartilage destruction · Granzyme B · Rheumatoid arthritis · collagen · glycosaminoglycan · granzyme B · hydroxyproline · proline · proteoglycan · sulfate · sulfur 35 · tritium · animal tissue · bone erosion · cartilage degeneration · cartilage matrix · collagen degradation · controlled study · explant · human cell · immunohistochemistry · isotope labeling · joint destruction · nonhuman · priority journal · protein denaturation · protein expression · proteoglycan synthesis · rheumatoid arthritis · synovium · Animals · Arthritis, Rheumatoid · Cartilage · Cattle · Cells, Cultured · Chondrocytes · Collagen · Extracellular Matrix · Granzymes · Humans · Metacarpophalangeal Joint · Proteoglycans · Serine Endopeptidases · Synovial Membrane
[Abstract]

6 Compositional and metabolic changes in damaged cartilage are peak- stress, stress-rate, and loading-duration dependent
article 1999    
Author: Chen, C.-T. · Burton-Wurster, N. · Lust, G. · Bank, R.A. · Tekoppele, J.M.
Keywords: Biology · Biomedical Research · Biosynthesis · Compression testing · Impact testing · Metabolism · Monoclonal antibodies · Stress analysis · Tissue culture · Articular cartilage · Monoclonal antibody · Proteoglycan · Animal tissue · Articular cartilage · Cartilage degeneration · Cartilage matrix · Collagen degradation · Compression · Controlled study · Explant · Nonhuman · Proteoglycan synthesis · Shear stress · Tissue metabolism · Water content · Weight bearing · Animal · Cartilage · Collagen · Dogs · Fibronectins · Glycosaminoglycans · Immunohistochemistry · Osteoarthritis · Stress, Mechanical · Support, U.S. Gov't, P.H.S. · Time Factors · Water
[Abstract]

7 Effect of the anti-tumor necrosis factor-α antibody infliximab on the ex vivo mucosal matrix metalloproteinase-proteolytic phenotype in inflammatory bowel disease
article 2007    
Author: Meijer, M.J. · Mieremet-Ooms, M.A.C. · Duijn, W. van · Zon, A.M. van der · Hanemaaijer, R. · Verheijen, J.H. · Hogezand, R.A. van · Lamers, C.B.H.W. · Verspaget, H.W.
Keywords: Biomedical Research · Inflammatory bowel disease · Infliximab · Matrix metalloproteinase · Tissue inhibitor of metalloproteinase · Tumor necrosis factor-alpha · azathioprine · cyclosporin · gelatinase A · gelatinase B · infliximab · interstitial collagenase · mesalazine · messenger RNA · pokeweed mitogen · steroid · stromelysin · tissue inhibitor of metalloproteinase 1 · tissue inhibitor of metalloproteinase 2 · tumor necrosis factor alpha antibody · adolescent · adult · aged · article · clinical article · controlled study · Crohn disease · drug effect · enteritis · explant · female · genotype · human · human tissue · intestine mucosa · male · priority journal · protein degradation · protein expression · single nucleotide polymorphism · ulcerative colitis · Adolescent · Adult · Aged · Antibodies, Monoclonal · Colitis, Ulcerative · Crohn Disease · Down-Regulation · Female · Humans · Intestinal Mucosa · Male · Matrix Metalloproteinases · Middle Aged · Phenotype · Polymorphism, Single Nucleotide · Reverse Transcriptase Polymerase Chain Reaction · Tissue Culture Techniques · Tissue Inhibitor of Metalloproteinases · Tumor Necrosis Factor-alpha
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 7 of 7 found. | Sort by date