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1 Enzyme kinetics and substrate selectivities of rat glutathione S-transferase isoenzymes towards a series of new 2-substituted 1-chloro-4-nitrobenzenes
article 1996    
Author: Aar, E.M. van der · Buikema, D. · Commandeur, J.N.M. · Koppele, J.M. te · Ommen, B. van · Bladeren, P.J. van · Vermeulen, N.P.E.
Keywords: Nutrition · glutathione transferase · isoenzyme · nitrobenzene derivative · animal tissue · article · controlled study · enzyme kinetics · enzyme specificity · glutathione metabolism · nonhuman · rat · Animals · Chromatography, Affinity · Dinitrochlorobenzene · Glutathione Transferase · Isoenzymes · Kidney · Kinetics · Liver · Rats · Spectrophotometry, Ultraviolet · Substrate Specificity · Animalia · Felis catus
[Abstract]

2 GSTP1-1 stereospecifically catalyzes glutathione conjugation of ethacrynic acid
article 1998    
Author: Iersel, M.L.P.S. van · Lipzig, M.M.H. van · Rietjens, I.M.C.M. · Vervoort, J. · Bladeren, P.J. van
Keywords: EA, ethacrynic acid · Ethacrynic acid · Glutathione S-transferase · Stereoselectivity · Etacrynic acid · Glutathione · Glutathione transferase · Multidrug resistance protein · Chemical reaction · Conjugate · Controlled study · Diastereoisomer · Drug conjugation · Enzyme mechanism · Glutathione metabolism · Human cell · Melanoma cell · Nuclear magnetic resonance spectroscopy · Stereochemistry · Amino Acid Substitution · Ethacrynic Acid · Glutathione · Glutathione Transferase · Humans · Isoenzymes · Melanoma · Point Mutation · Stereoisomerism · Substrate Specificity · Tumor Cells, Cultured
[PDF] [Abstract]

3 Human glutathione S-transferase-mediated glutathione conjugation of curcumin and efflux of these conjugates in caco-2 cells
article 2007    
Author: Usta, M. · Wortelboer, H.M. · Vervoort, J. · Boersma, M.G. · Rietjens, I.M.C.M. · Bladeren, P.J. van · Cnubben, N.H.P.
Keywords: Biology · Toxicology and Applied Pharmacology · curcumin · glutathione transferase · adult · aged · article · atom · catalysis · cell strain CACO 2 · conjugate · drug degradation · drug excretion · drug structure · female · glutathione metabolism · human · human cell · human tissue · intestine · intestine epithelium cell · liquid chromatography · liver cytosol · male · mass spectrometry · monolayer culture · proton nuclear magnetic resonance · Adult · Aged · Caco-2 Cells · Curcumin · Cytosol · Female · Glutathione · Glutathione Transferase · Humans · Intestines · Liver · Magnetic Resonance Spectroscopy · Male · Metabolic Detoxication, Phase II · Middle Aged · Molecular Structure
[Abstract]

4 Toxicogenomics of bromobenzene hepatotoxicity: A combined transcriptomics and proteomics approach
article 2003    
Author: Heijne, W.H.M. · Stierum, R.H. · Slijper, M. · Bladeren, P.J. van · Ommen, B. van
Keywords: Toxicology Health · Physiological Sciences · Bromobenzene · cDNA microarray · Hepatotoxicity · Proteomics · Toxicogenomics · Transcriptomics · alpha glutamylcysteine synthetase · bromobenzene · cathepsin L · enzyme · epoxide hydrolase · glutathione · glutathione transferase · heme oxygenase · messenger RNA · peroxiredoxin · proteasome · unclassified drug · animal experiment · animal model · animal tissue · article · controlled study · enzyme activity · enzyme induction · enzyme regulation · enzyme subunit · gene control · gene expression · gene identification · gene induction · genomics · glutathione metabolism · liver toxicity · lysosome · male · nonhuman · nucleotide sequence · oxidative stress · priority journal · protein content · protein degradation · protein depletion · protein expression · protein synthesis · proteomics · rat · RNA analysis · tissue level · unindexed sequence · weight reduction · Animals · Bromobenzenes · Liver · Male · Oligonucleotide Array Sequence Analysis · Pharmacogenetics · Proteomics · Rats · Rats, Wistar · Transcription, Genetic
[Abstract]

5 Health issues of whey proteins: 1. Protection of lean body mass
article 2006    
Author: Schaafsma, G.
Keywords: Biology · Biomedical Research · Clinical states · Muscle mass protection · Sarcopenia · Weight loss · Whey proteins · branched chain amino acid · cysteine · essential amino acid · glucose · glutamine · glutathione · milk protein · amino acid composition · burn · cancer · catabolism · chronic obstructive lung disease · Crohn disease · decarboxylation · diabetes mellitus · digestive function · energy metabolism · exercise · glucose homeostasis · glutathione metabolism · health program · host resistance · human · Human immunodeficiency virus infection · insulin resistance · kidney disease · lean body weight · muscle atrophy · non insulin dependent diabetes mellitus · nonhuman · nutritional assessment · nutritional requirement · nutritional status · nutritional value · protein degradation · protein diet · protein function · protein intake · protein metabolism · protein synthesis · review · sepsis · statistical significance · surgical injury · transamination · weight reduction · whey · wound healing
[Abstract]

6 Inhibition of multidrug resistance proteins MRP1 and MRP2 by a series of α,β-unsaturated carbonyl compounds
article 2005    
Author: Wortelboer, H.M. · Usta, M. · Zanden, J.J. van · Bladeren, P.J. van · Rietjens, I.M.C.M. · Cnubben, N.H.P.
Keywords: Nutrition · Biomedical Research · α,β-Unsaturated carbonyl compounds · Inhibition · MRP1 · MRP2 · 2 hexenal · acrolein · caffeic acid phenethyl ester · calcein · carbonyl derivative · cinnamaldehyde · citral · crotonaldehyde · curcumin · cyclosporin A · demethoxycurcumin · didemethoxycurcumin · drug metabolite · glutathione · multidrug resistance protein 1 · multidrug resistance protein 2 · thiol derivative · unclassified drug · verlukast · animal cell · article · cell isolation · cell metabolism · conjugate · controlled study · dog · drug efficacy · drug metabolism · drug potency · drug protein binding · glutathione metabolism · kidney cell · membrane vesicle · modulation · molecular model · molecular stability · nonhuman · priority journal · protein expression · protein transport · Aldehydes · Animals · Biological Transport · Cell Line · Curcumin · Dogs · Fluoresceins · Humans · Membrane Transport Modulators · Membrane Transport Proteins · Multidrug Resistance-Associated Proteins · Transfection
[Abstract]

7 Toxicogenomic analysis of gene expression changes in rat liver after a 28-day oral benzene exposure
article 2005    
Author: Heijne, W.H.M. · Jonker, D. · Stierum, R.H. · Ommen, B. van · Groten, J.P.
Keywords: Toxicology Biology · Toxicology and Applied Pharmacology · Benzene · cDNA microarrays · Gene expression · Hepatotoxicity · Metabolomics · Toxicogenomics · Transcriptomics · benzene · bromobenzene · paracetamol · animal experiment · animal tissue · biotransformation · blood toxicity · cholesterol metabolism · conference paper · DNA microarray · gene expression · genetic analysis · genetic toxicology · glutathione metabolism · liver necrosis · liver weight · male · nonhuman · nuclear magnetic resonance spectroscopy · nucleotide sequence · priority journal · rat · rat strain · unindexed sequence · Animals · Benzene · Blood Cell Count · Cholesterol · Fatty Acids · Gene Expression Profiling · Gene Expression Regulation · Hemoglobins · Liver · Male · Mutagens · Oligonucleotide Array Sequence Analysis · Organ Size · Rats · Rats, Inbred F344 · Spleen · Thymus Gland · Time Factors · Urinalysis · Martes pennanti
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 7 of 7 found. | Sort by date