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1 Prophylactic and therapeutic effects of a humanized monoclonal antibody against the IL-2 receptor (DACLIZUMAB) on collagen-induced arthritis (CIA) in rhesus monkeys
article 2001    
Author: Brok, H.P.M. · Tekoppele, J.M. · Hakimi, J. · Kerwin, J.A. · Nijenhuist, E.M. · Groot, C.W.de · Bontrop, R.E. · Hart 't, B.A.
Keywords: Biology · Biomedical Research · Animal model · Inflammation · Joint destruction · Nonhuman primate · Rheumatoid arthritis · Collagen · Interleukin 2 receptor · Interleukin 2 receptor antibody · Monoclonal antibody · Animal experiment · Animal model · Autoimmune disease · Controlled study · Drug blood level · Drug half life · Immunization · Immunogenicity · Inflammation · Joint destruction · Male · Nonhuman · Priority journal · Prophylaxis · Rhesus monkey · Rheumatoid arthritis · Animals · Antibodies, Monoclonal · Antibody Specificity · Arthritis, Rheumatoid · Autoantibodies · Autoimmune Diseases · C-Reactive Protein · Collagen · Disease Models, Animal · Drug Evaluation, Preclinical · Humans · Hydroxyproline · Immunization · Immunoglobulin G · Macaca mulatta · Male · Receptors, Interleukin-2 · Weight Loss
[Abstract]

2 Decreased sensitivity to dexamethasone in lymphocytes from patients with Alzheimer's disease
article 1994    
Author: Nijhuis, E. · Hinloopen, B. · Duijn, C. van · Hofman, A. · Rozing, J. · Nagelkerken, L.
Keywords: Health · cd4 antigen · dexamethasone · glucocorticoid · hydrocortisone · interleukin 2 · interleukin 4 · clinical article · clinical trial · controlled clinical trial · controlled study · Male · t lymphocyte subpopulation · Aged · Alzheimer Disease · Dexamethasone · Female · Humans · Lymphocyte Activation · Phenotype · Sensitivity and Specificity · T-Lymphocytes
[Abstract]

3 Identification and monitoring of effector and regulatory T cells during experimental arthritis based on differential expression of CD25 and CD134
article 2008    
Author: Nolte-'t Hoen, E.N.M. · Boot, E.P.J. · Wagenaar-Hilbers, J.P.A. · Bilsen, J.H.M. van · Arkesteijn, G.J.A. · Storm, G. · Everse, L.A. · Eden, W. van · Wauben, M.H.M.
Keywords: Biology · FoxP3 · Immune regulation · Kinetics · Lymph nodes · CD134 antigen · interleukin 2 receptor alpha · transcription factor FOXP3 · animal cell · animal experiment · animal model · arthritis · article · CD25+ T lymphocyte · CD4+ T lymphocyte · cell activation · cell differentiation · cell proliferation · controlled study · effector cell · lymph node · male · memory T lymphocyte · nonhuman · phenotype · priority journal · protein analysis · protein expression · protein function · protein isolation · protein localization · rat · regulatory T lymphocyte · Animals · Arthritis, Experimental · Disease Models, Animal · Disease Progression · Forkhead Transcription Factors · Interleukin-2 Receptor alpha Subunit · Male · Rats · Rats, Inbred Lew · Receptors, OX40 · T-Lymphocytes, Regulatory · Rattus
[Abstract]

4 Strain-dependent induction of cytokine profiles in the gut by orally administered Lactobacillus strains
article 2000    
Author: Maassen, C.B.M. · Holten-Neelen, C. van · Balk, F. · Bak-Glashouwer, M.-J.H. den · Leer, R.J. · Laman, J.D. · Boersma, W.J.A. · Claassen, E.
Keywords: Immunohistochemistry · Mucosal immune response · Probiotic · adjuvant · cytokine · gamma interferon · immunoglobulin A · interleukin 10 · interleukin 1alpha · interleukin 1beta · interleukin 2 · interleukin 4 · probiotic agent · tumor necrosis factor alpha · animal experiment · animal model · antibody response · article · controlled study · cytokine production · enzyme linked immunosorbent assay · female · humoral immunity · immune response · immunohistochemistry · intestine mucosa · Lactobacillus · Lactobacillus brevis · Lactobacillus casei · Lactobacillus fermentum · Lactobacillus plantarum · Lactobacillus reuteri · mouse · mucosa · nonhuman · priority journal · Adjuvants, Immunologic · Administration, Oral · Animals · Chickens · Chikungunya virus · Cytokines · Duodenum · Female · Food Microbiology · gamma-Globulins · Haptens · Injections, Intraperitoneal · Interleukin-2 · Intestinal Mucosa · Lactobacillus · Lactobacillus casei · Mice · Mice, Inbred BALB C · Microvilli · Peyer's Patches · Species Specificity · Th2 Cells · Viral Vaccines
[Abstract]

5 Recombinant adenoviral vectors have adjuvant activity and stimulate T cell responses against tumor cells
article 2000    
Author: Geutskens, S.B. · Eb, M.M. van der · Plomp, A.C. · Jonges, L.E. · Cramer, S.J. · Ensink, N.G. · Kuppen, P.J.K. · Hoeben, R.C.
Keywords: Cancer gene therapy · IL-2 · Recombinant adenovirus · complementary DNA · cytokine · recombinant interleukin 2 · tumor antigen · virus vector · Adenovirus · Animal cell · Animal experiment · Animal model · Antigen recognition · Antineoplastic activity · Cancer inhibition · Colorectal cancer · Controlled study · Delayed hypersensitivity · DNA transfer · Gene expression · Gene therapy · immune response · Immunotherapy · Liver metastasis · Lymphocyte activation · Nonhuman · Rat strain · T lymphocyte · Transgene · Tumor cell · Tumor regression · Virus plaque · Virus recombinant · Virus replication · Adenoviridae · Animals · Colorectal Neoplasms · Flow Cytometry · Gene Therapy · Genetic Vectors · Histocompatibility Antigens Class I · Histocompatibility Antigens Class II · Humans · Intercellular Adhesion Molecule-1 · Interleukin-2 · Liver Neoplasms, Experimental · Lymphocyte Activation · Rats · Rats, Inbred Strains · T-Lymphocytes · Tumor Cells, Cultured · Adenoviridae · Animalia · DNA viruses
[Abstract]

6 CD4+CD25+ T cells regulate the intensity of hypersensitivity responses to peanut, but are not decisive in the induction of oral sensitization
article 2007    
Author: Wijk, F. van · Wehrens, E.J.M. · Nierkens, S. · Boon, L. · Kasran, A. · Pieters, R. · Knippels, L.M.J.
Keywords: Nutrition · Toxicology and Applied Pharmacology · Allergic sensitization · CD25+ regulatory T cells · Oral tolerance · Peanut allergy · CD4+ CD25+ T lymphocyte · sensitization · Administration, Oral · Animals · Cells, Cultured · Cytokines · Female · Immune Tolerance · Immunoglobulin E · Immunoglobulin G · Interleukin-2 Receptor alpha Subunit · Lymphocyte Depletion · Mice · Mice, Inbred C3H · Peanut Hypersensitivity · Plant Extracts · T-Lymphocytes, Regulatory
[Abstract]

7 Age-related changes in immune reactivity: The influence of intrinsic defects and of a changed composition of the CD4+ T cell compartment
article 1992    
Author: Nijhuis, E.W.P. · Nagelkerken, L.
Keywords: Biology · CD4+ T cell subsets · CD45 isoforms · Interleukin-4 · Cd4 antigen · Cd45 antigen · Immunoreactivity · Immunoregulation · Memory cell · T lymphocyte · T lymphocyte activation · T lymphocyte subpopulation · Thymus · Aging · Animal · Antigens, CD45 · CD4-Positive T-Lymphocytes · Human · Immunocompetence · Immunologic Memory · Interleukin-2 · Leukocyte Count · Mice · Thymus Gland
[Abstract]

8 Differences in dexamethasone-sensitivity between lymphocytes from patients with Alzheimer's disease and patients with multi-infarct dementia
article 1996    
Author: Nijhuis, E.W.P. · Oostervink, F. · Hinloopen, B. · Rozing, J. · Nagelkerken, L.
Keywords: Health · Glucocorticoid receptor · Clinical article · Cognitive defect · Drug sensitivity · Human cell · Lymphocyte · Mononuclear cell · Multiinfarct dementia · Screening · Aged · Aged, 80 and over · Alzheimer Disease · Apoptosis · Cells, Cultured · Dementia, Multi-Infarct · Dexamethasone · Drug Resistance · Female · Gene Expression Regulation · Humans · Immunosuppressive Agents · Interleukin-2 · Interleukin-4 · Lymphocyte Activation · Male · Phytohemagglutinins · Proto-Oncogene Proteins c-bcl-2 · Receptors, Glucocorticoid · T-Lymphocytes
[Abstract]

9 Synovial inflammation, immune cells and their cytokines in osteoarthritis: A review
article 2012    
Author: Lange-Brokaar, B.J.E. de · Ioan-Facsinay, A. · Osch, G.J.V.M. van · Zuurmond, A.-M. · Schoones, J. · Toes, R.E.M. · Huizinga, T.W.J. · Kloppenburg, M.
Keywords: Cytokines · Histology · Immune cells · Inflammation · Osteoarthritis · Synovial tissue · gamma interferon · interleukin 10 · interleukin 18 · interleukin 1beta · interleukin 2 · interleukin 4 · interleukin 6 · interleukin 8 · transforming growth factor beta · tumor necrosis factor alpha · cell infiltration · cytokine release · hip arthroplasty · immunocompetent cell · immunohistochemistry · information retrieval · knee arthroscopy · macrophage · mast cell · needle biopsy · osteoarthritis · priority journal · review · rheumatoid arthritis · synovectomy · synovitis · T lymphocyte · Healthy Living · Life · MHR - Metabolic Health Research · EELS - Earth, Environmental and Life Sciences
[Abstract]

10 Expression of accessory molecules and cytokines in acute EAE in marmoset monkeys (Callithrix jacchus)
article 1998    
Author: Laman, J.D. · Meurs, M. van · Schellekens, M.M. · Boer, M. de · Melchers, B. · Massacesi, L. · Lassmann, H. · Claassen, E. · Hart, B.A. 't
Keywords: Health · CD40 · CD80 · CD86 · Macrophages · Multiple sclerosis · Non-human primates · Acid Phosphatase · Animals · Antigens, CD · Antigens, CD40 · Antigens, CD80 · Antigens, CD86 · Brain · Brain Chemistry · Callithrix · Cytokines · Disease Models, Animal · Encephalomyelitis, Autoimmune, Experimental · Female · Histocompatibility Antigens Class II · HLA-DR Antigens · Interferon Type II · Interferon-alpha · Interleukin-1 · Interleukin-10 · Interleukin-12 · Interleukin-2 · Interleukin-4 · Macrophages · Male · Membrane Glycoproteins · Multiple Sclerosis · Tumor Necrosis Factor-alpha
[Abstract]

11 Increased sensitivity to glucocorticoids in peripheral blood mononuclear cells of chronic fatigue syndrome patients, without evidence for altered density or affinity of glucocorticoid receptors
article 2001    
Author: Visser, J. · Lentjes, E. · Haspels, I. · Graffelman, W. · Blauw, B. · Kloet, R. de · Nagelkerken, L.
Keywords: Health · Chronic fatigue syndrome · Glucocorticoid receptors · Glucocorticoids · Dexamethasone · Gamma interferon · Glucocorticoid · Glucocorticoid receptor · Interleukin 10 · Interleukin 2 · Iessenger RNA · Phorbol 13 acetate 12 myristate · Tumor necrosis factor alpha · Clinical article · controlled study · Corticotropin blood level · Cytokine production · Enzyme linked immunosorbent assay · Hormone sensitivity · Human cell · Hydrocortisone blood level · Mononuclear cell · receptor affinity · receptor density · reverse transcription polymerase chain reaction · Adolescent · Adrenocorticotropic Hormone · Adult · Cells, Cultured · Cytokines · Dexamethasone · Fatigue Syndrome, Chronic · Female · Humans · Hydrocortisone · Leukocytes, Mononuclear · Male · Middle Aged · Receptors, Glucocorticoid · Tetradecanoylphorbol Acetate
[Abstract]

12 Cytokines and atherosclerosis: A comprehensive review of studies in mice
article 2008    
Author: Kleemann, R. · Zadelaar, A.S.M. · Kooistra, T.
Keywords: Health · Atherosclerosis · Cytokines · Macrophage · Gamma interferon · Granulocyte colony stimulating factor · Granulocyte macrophage colony stimulating factor · Interleukin 1 · Interleukin 10 · Interleukin 12 · Interleukin 18 · Interleukin 2 · Interleukin 20 · Interleukin 3 · Interleukin 4 · Interleukin 5 · Interleukin 6 · Atherogenesis · Diet · Gene deletion · Gene overexpression · Mouse strain · Nonhuman · Outcome assessment · Protein expression · Review · Sex difference · Animals · Atherosclerosis · Colony-Stimulating Factors · Cytokines · Disease Models, Animal · Inflammation · Interferon-gamma · Interleukins · Macrophage Migration-Inhibitory Factors · Mice · Signal Transduction · Tumor Necrosis Factor-alpha
[Abstract]

13 Detection of the mechanism of immunotoxicity of cyclosporine A in murine in vitro and in vivo models
article 2015    
Author: Schmeits, P.C.J. · Schaap, M.M. · Luijten, M. · Someren, E. van · Boorsma, A. · Loveren, H. van · Peijnenburg, A.A.C.M. · Hendriksen, P.J.M.
Keywords: Biology · C57BL/6 · CTLL-2 · Cyclosporine A · Interspecies comparison · Splenocytes · Interleukin 2 · Messenger RNA · Transcription factor Nrf2 · Animal cell · Animal experiment · Cell cycle regulation · Controlled study · Cytotoxic T lymphocyte · Down regulation · Endoplasmic reticulum stress · HepG2 cell line · Human · Human cell · Immune response · Immunotoxicity · In vitro study · In vivo study · Jurkat cell line · Male · Mouse · Nonhuman · Dpleen cell · T lymphocyte activation · Thymoma cell line · Transcriptomics · Unfolded protein response · Upregulation · Biomedical Innovation · Healthy Living · Life · RAPID - Risk Analysis for Products in Development · ELSS - Earth, Life and Social Sciences
[Abstract]

14 Effects of cis-9, trans-11 and trans-10, cis-12 conjugated linoleic acid (CLA) isomers on immune function in healthy men
article 2003    
Author: Albers, R. · Wielen, R.P.J. van der · Brink, E.J. · Hendriks, H.F.J. · Dorovska-Taran, V.N. · Mohede, I.C.M.
Keywords: Health · Physiological Sciences · Conjugated linoleic acid (CLA) · Fatty acids · Human · Immune function · Immune modulation · acylglycerol · engerix · fatty acid · gamma interferon · hepatitis B antibody · interleukin 1beta · interleukin 2 · interleukin 4 · interleukin 6 · linoleic acid · prostaglandin E2 · recombinant hepatitis B vaccine · sunflower oil · tumor necrosis factor alpha · adult · aged · antibody blood level · article · clinical trial · controlled clinical trial · controlled study · cytokine production · diet supplementation · double blind procedure · drug capsule · hepatitis B · human · human experiment · immune response · immune system · immunostimulation · isomer · lymphocyte proliferation · male · natural killer cell · normal human · randomized controlled trial · vaccination · Adult · Aged · Dinoprostone · Double-Blind Method · Hepatitis B Antibodies · Hepatitis B Vaccines · Humans · Hypersensitivity, Delayed · Immunity · Interferon Type II · Interleukins · Isomerism · Killer Cells, Natural · Leukocytes, Mononuclear · Linoleic Acid · Lymphocyte Activation · Male · Middle Aged · Tumor Necrosis Factor-alpha · Vaccination · Helianthus
[Abstract]

15 Developmental immunotoxicity of methylmercury: The relative sensitivity of developmental and immune parameters
article 2010    
Author: Tonk, E.C.M. · Groot, D.M.G. de · Penninks, A.H. · Waalkens - Berendsen, I.D.H. · Wolterbeek, A.P.M. · Slob, W. · Piersma, A.H. · Loveren, H. van
Keywords: Toxicology · Biomedical Research · Benchmark dose · Developmental immunotoxicity · Developmental toxicity · Dose-response modeling · Methylmercury · Perinatal exposure · Rat · gamma interferon · interleukin 10 · interleukin 13 · interleukin 2 · interleukin 4 · interleukin 6 · keyhole limpet hemocyanin · methylmercury · T lymphocyte antibody · adherent cell · animal tissue · antibody response · article · basophil · body weight · CD3+ T lymphocyte · CD4 CD8 ratio · CD8+ T lymphocyte · clinical evaluation · controlled study · cytokine production · delayed hypersensitivity · developmental screening · diagnostic value · environmental exposure · epididymis · erythrocyte · female · gestational age · immunological parameters · immunotoxicity · kidney mass · leukocyte count · litter size · liver weight · lymphocyte proliferation · natural killer cell · newborn mortality · nonhuman · rat · reticulocyte count · sensitivity and specificity · spleen cell · spleen weight · stillbirth · testis weight · thrombocyte count · thymus · weight reduction
[Abstract]

16 Protective and therapeutic role for αB-crystallin in autoimmune demyelination
article 2007    
Author: Ousman, S.S. · Tomooka, B.H. · Noort, J.M. van · Wawrousek, E.F. · O'Conner, K. · Hafler, D.A. · Sobel, R.A. · Robinson, W.H. · Steinman, L.
Keywords: Biomedical Research · caspase 3 · cytokine · gamma interferon · interleukin 12p40 · interleukin 17 · interleukin 2 · recombinant alphab crystallin · recombinant protein · tumor necrosis factor · antibody · brain · gene · immune response · immune system · nervous system disorder · rodent · allergic encephalomyelitis · animal cell · animal experiment · animal model · animal tissue · apoptosis · article · astrocyte · central nervous system · cerebrospinal fluid · controlled study · cytokine release · demyelination · female · gene function · human · immune response · immune system · macrophage · mouse · multiple sclerosis · myelin sheath · nick end labeling · nonhuman · priority journal · T lymphocyte · Th1 cell · wild type · alpha-Crystallin B Chain · Animals · Apoptosis · Astrocytes · Caspase 3 · Encephalomyelitis, Autoimmune, Experimental · Humans · Inflammation · Macrophages · MAP Kinase Signaling System · Mice · Multiple Sclerosis · Myelin Sheath · Neuroglia · Neuroprotective Agents · NF-kappa B · T-Lymphocytes, Helper-Inducer · Mus
[Abstract]

17 Inflammation and nutritional science for programs/policies and interpretation of research evidence (INSPIRE)
article 2015    
Author: Raiten, D.J. · Sakr Ashour, F.A. · Ross, A.C. · Meydani, S.N. · Dawson, H.D. · Stephensen, C.B. · Brabin, B.J. · Suchdev, P.S. · Ommen, B. van · Ahluwalia, N. · Ahmed, T. · Allen, L. · Beck, M. · Blanchard, H. · Brindle, E. · Brown, K. · Calder, P. · Checkley, W. · Claycombe, K. · Coles, C. · Esamai, F. · Friis, H. · Gardner, E. · Grinspoon, S. · Guerrant, R. · Hellerstein, M. · Hunt, J. · King, J. · Klasing, K. · Kramer, B. · Koski, K. · Northrop-Clewes, C. · Pfeiffer, C. · Prentice, A. · Ramirez-Zea, M. · Rheenan, P. van · Rink, L. · Srinivasa, S. · Benn, C.S. · Stephensen, C. · Suchdev, P. · Sullivan, K. · Thurnham, D. · Varadhan, R. · Van Der Ven, A. · Walston, J. · Xia, J.
Keywords: Biology · Assessment of micronutrient biomarkers · BOND and inflammation/infection · Immune function and nutrients · Inflammation and nutrition · Nutrition biomarkers · Albumin · Alpha tocopherol · Antiinflammatory agent · Biological marker · C reactive protein · Calcitonin · Cyanocobalamin · Folic acid · Hemoglobin · Immunoglobulin enhancer binding protein · Interleukin 2 · Interleukin 6 · Iodine · Iron · Nonsteroid antiinflammatory agent · Procalcitonin · Retinoic acid · Retinol · Steroid · Tumor necrosis factor · Tumor necrosis factor alpha · Vitamin D · Vitamin D deficiency · Vitamin supplementation · Zinc · Acute phase response · Acute stress · Adaptive immunity · Anemia · Asthma · Cell activity · Chronic inflammation · Chronic obstructive lung disease · Chronic stress · DNA polymorphism · Drug exposure · Enteropathy · Epigenetics · Evidence based practice · Fetus disease · Health care policy · Health program · Immune response · Immune system · Infant disease · Inflammation · Inflammatory disease · Innate immunity · Iron deficiency · Leukocyte · Malaria · Malnutrition · Mastitis · Medical research · Meta analysis (topic) · Mixed infection · Multicenter study (topic) · Muscle atrophy · Non communicable disease · Nonhuman · Nutrient · Nutritional science · Nutritional status · Obesity · Organizational structure · Oxidative stress · Parasitosis · Phase 1 clinical trial (topic) · Point of care testing · Practice guideline · Pregnancy complication · Pregnancy outcome · Prematurity · Protein calorie malnutrition · Randomized controlled trial (topic) · Regulatory T lymphocyte · Research priority · Retinol deficiency · Risk assessment · Signal transduction · Stunting · Systematic review (topic) · Underweight · Zinc deficiency · Biomedical Innovation · Healthy Living · Life · MSB - Microbiology and Systems Biology · ELSS - Earth, Life and Social Sciences
[Abstract]

18 Enhanced expression and activation of pro-inflammatory transcription factors distinguish aneurysmal from atherosclerotic aorta: IL-6- and IL-8-dominated inflammatory responses prevail in the human aneurysm
article 2008    
Author: Lindeman, J.H.N. · Abdul-Hussien, H. · Schaapherder, A.F.M. · Bockel, J.H. van · Thüsen, J.H. vonder · Roelen, D.L. · Kleemann, R.
Keywords: Health · Abdominal aortic aneurysm · Atherosclerosis · Inflammation · Interleukin · Transcription factor · CCAAT enhancer binding protein alpha · CCAAT enhancer binding protein beta · CCAAT enhancer binding protein delta · Cytokine · Gamma interferon · Interleukin 10 · Interleukin 13 · Interleukin 1alpha · Interleukin 2 · Interleukin 4 · Interleukin 6 · Interleukin 8 · Messenger RNA · Perforin · STAT3 protein · transcription factor · transcription factor AP 1 · transcription factor GATA 3 · transcription factor RelA · transcription factor T bet · tumor necrosis factor alpha · autacoid · biological marker · abdominal aorta aneurysm · adult · aged · aorta atherosclerosis · aorta wall · B lymphocyte · Cellular immunity · Clinical article · Controlled study · Cytotoxic T lymphocyte · Enzyme linked immunosorbent assay · Female · Human · Human tissue · Immunohistochemistry · Male · Medical parameters · Neutrophil · Plasma cell · Protein expression · Real time polymerase chain reaction · Th1 cell · Th2 cell · Vasa vasorum · Western blotting · Aorta valve stenosis · Biosynthesis · Differential diagnosis · Genetics · Immunology · Metabolism · Methodology · Physiology · Reverse transcription polymerase chain reaction · Aged · Aortic Aneurysm, Abdominal · Aortic Valve Stenosis · Atherosclerosis · Biological Markers · Diagnosis, Differential · Female · Gene Expression Profiling · Humans · Inflammation Mediators · Male · Middle Aged · Reverse Transcriptase Polymerase Chain Reaction · Th1 Cells · Th2 Cells · Transcription Factors
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 18 of 18 found. | Sort by date