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1 Nieuw ontdekte diabetes mellitus bij kinderen: Wel of niet opnemen?
article 1996    
Author: Hirasing, R.A. · Reeser, H.M. · Goor, J. van · Bruining, G.J.
Keywords: Health · Insulin · Child · Diabetes mellitus · Hospitalization · Human · Intravenous drug administration
[Abstract]

2 Presentatie bij diagnose van insuline afhankelijke Diabetes Mellitus in Nederland
article 1995    
Author: Reeser, H.M. · Hirasing, R.A.
Keywords: Health · Insulin · Child · Diabetes mellitus · Hospitalization · Human · Intravenous drug administration

3 Defibrinogenation by Arvin reduces air-drying-induced arteriosclerosis in rat carotid artery
article 1989    
Author: Pelt-Verkuil, E. van · Ree, P. van de · Emeis, J.J.
Keywords: Animal experiment · Defibrinogenation · Intravenous drug administration · Nonhuman · Air · Ancrod · Animal · Arteriosclerosis · Carotid Artery Diseases · Fibrinogen · Male · Rats · Rats, Inbred Strains
[Abstract]

4 Pharmacokinetics and bioavailability of dapsone in the beagle dog
article 1989    
Author: Hekman, P. · Rens, P. van · Rietvel, E.C. · Coert, A.
Keywords: Nutrition · Dapsone · Animal experiment · Dog · Drug bioavailability · Drug blood level · Drug determination · Intravenous drug administration · Nonhuman · Oral drug administration · Preliminary communication
[Abstract]

5 Modification of the early and late delayed radiation response of the rat spinal cord by chemotherapeutic agents
article 1981    
Author: Kogel, A.J. van der
Keywords: cytarabine · methotrexate · abstract report · animal experiment · central nervous system · intramuscular drug administration · intrathecal drug administration · intravenous drug administration · radiation injury · rat · spinal cord
[Abstract]

6 Renal and hepatic handling of endogenous tissue-type plasminogen activator (t-PA) and its inhibitor in man
article 1988    
Author: Brommer, E.J.P. · Derkx, F.H.M. · Schalekamp, M.A.D.H. · Dooijewaard, G. · Klaauw, V.D.M.M.
Keywords: Fibrinolysis · Human experiment · Hypertension · Intravenous drug administration · Liver vein · Adult · Blood Coagulation Factors · Blood Specimen Collection · Catheterization · Desmopressin · Glycoproteins · Half-Life · Human · Kidney · Liver · Male · Middle Age · Plasminogen Activators · Plasminogen Inactivators · Support, Non-U.S. Gov't · Tissue Plasminogen Activator
[Abstract]

7 Persistence of the anti-cholinesterase soman in rats: Antagonism with a non-toxic simulator of this organophosphate
article 1981    
Author: Wolthuis, O.L. · Benschop, H.P. · Berends, F.
Keywords: Biology · Acetylcholinesterase · Atropine · Soman · Animal experiment · Controlled study · Drug intoxication · Intoxication · Intravenous drug administration · Rat · Simulator · Sustained release preparation · Acetylcholinesterase · Animal · Male · Organophosphorus Compounds · Pyridinium Compounds · Rats · Soman · Time Factors
[Abstract]

8 Extrapulmonary colony formation after intravenous injection of tumour cells into heparin treated animals
article 1978    
Author: Maat, B.
Keywords: fibrin · animal experiment · blood and hemopoietic system · blood clotting · cancer graft · colony formation · dose response · drug comparison · drug response · intraperitoneal drug administration · intravenous drug administration · lung · metastasis · mouse · respiratory system · theoretical study · Animal · Cell Count · Heparin · Lung Neoplasms · Mice · Neoplasm Circulating Cells · Neoplasm Metastasis · Neoplasms, Experimental · Rats · Thoracic Neoplasms
[PDF] [Abstract]

9 Methyl DNA adducts, DNA repair, and hypoxanthine-guanine phosphoribosyl transferase mutations in peripheral white blood cells from patients with malignant melanoma treated with dacarbazine and hydroxyurea
article 1996    
Author: Philip, P.A. · Souliotis, V.L. · Harris, A.L. · Salisbury, A. · Tates, A.D. · Mitchell, K. · Delft, J.H.M. van · Ganesan, T.S. · Kyrtopoulos, S.A.
Keywords: Biology · dacarbazine · hydroxyurea · hypoxanthine phosphoribosyltransferase · adult · aged · article · clinical article · dna adduct · dna repair · female · gene mutation · human · intravenous drug administration · leukocyte · male · melanoma · priority journal · Antineoplastic Combined Chemotherapy Protocols · Dacarbazine · DNA Adducts · DNA Repair · Female · Guanine · Humans · Hydroxyurea · Hypoxanthine Phosphoribosyltransferase · Leukocytes · Male · Melanoma · Middle Aged · Mutation · O(6)-Methylguanine-DNA Methyltransferase
[Abstract]

10 Influence of amifostine on the pharmacokinetics of cisplatin in cancer patients
article 1998    
Author: Korst, A.E.C. · Sterre, M.L.T. van der · Gall, H.E. · Fichtinger-Schepman, A.M.J. · Vermorken, J.B. · Vijgh, W.J.F. van der
Keywords: Nutrition · Amifostine · Cisplatin · Creatinine · Adult · Aged · Area under the curve · Clinical article · Creatinine blood level · Dna adduct · Dna drug complex · Drug blood level · Drug effect · Drug half life · Female · Human · Intravenous drug administration · Kidney function · Male · Malignant neoplastic disease · Priority journal · Amifostine · Antineoplastic Agents · Cisplatin · DNA Adducts · Drug Interactions · Female · Half-Life · Hemofiltration · Humans · Leukocytes · Male · Middle Aged · Neoplasms · Platinum · Radiation-Protective Agents
[Abstract]

11 Pharmacokinetics of carboplatin with and without amifostine in patients with solid tumors
article 1997    
Author: Korst, A.E.C. · Sterre, M.L.T. van der · Eeltink, C.M. · Fichtinger-Schepman, A.M.J. · Vermorken, J.B. · Vijgh, W.J.F. van der
Keywords: Pharmacology · Amifostine · Carboplatin · Adult · Blood sampling · Clinical article · Clinical trial · Controlled clinical trial · Creatinine blood level · Creatinine clearance · Drug blood level · Drug efficacy · Drug half life · Enzyme linked immunosorbent assay · Female · Human · Intravenous drug administration · Male · Phase 1 clinical trial · Solid tumor · Amifostine · Animals · Antineoplastic Agents · Carboplatin · Dose-Response Relationship, Drug · Half-Life · Kidney · Kidney Function Tests · Metabolic Clearance Rate · Mice · Mice, Nude · Neoplasms
[Abstract]

12 Protein metabolism in the rat cerebral cortex in vivo and in vitro as affected by the acquisition enhancing drug piracetam
article 1976    
Author: Nickolson, V.J. · Wolthuis, O.L.
Keywords: Biology · Piracetam · Protein · Radioisotope · Brain · Brain cortex · In vitro study · Intracerebroventricular drug administration · Intraperitoneal drug administration · Intravenous drug administration · Leucine h 3 · Pharmacokinetics · Rat · Theoretical study · Animal · Cerebral Cortex · In Vitro · Leucine · Male · Nerve Tissue Proteins · Piracetam · Pyrrolidinones · Rats · Stimulation, Chemical · Time Factors
[Abstract]

13 The dependence of the blood level of the oxime HS 6 on the severity of organophosphate poisoning
article 1976    
Author: Wolthuis, O.L. · Clason-van der Wiel, H.J. · Visser, R.P.L.S.
Keywords: Biology · 1 (3 carbamoylpyridinio) 1' (2 hydroxyiminomethylpyridinio)dimethyl ether · Atropine · Cholinesterase inhibitor · Dimethyl ether · Soman · Drug analysis · Drug blood level · Drug intoxication · Intoxication · Intravenous drug administration · Pharmacokinetics · Plasma · Pralidoxime derivative · Rat · Respiratory failure · Theoretical study · Animal · Antidotes · Atropine · Dose-Response Relationship, Drug · Lethal Dose 50 · Male · Organophosphorus Compounds · Oximes · Rats · Soman
[Abstract]

14 Tumor necrosis factor increases the production of plasminogen activator inhibitor in human endothelial cells in vitro and in rats in vivo
article 1988    
Author: Hinsbergh, V.W.M. van · Kooistra, T. · Berg, E.A. van den · Princen, H.M.G. · Fiers, W. · Emeis, J.J.
Keywords: Interleukin 1 · Interleukin 6 · Lymphotoxin · Plasminogen activator inhibitor · Radioisotope · Tumor necrosis factor · Animal experiment · Animal model · Cell culture · Endothelium cell · Human · Human cell · Intravenous drug administration · Liver cell · Nonhuman · Animal · Blotting, Northern · Cells, Cultured · Endothelium, Vascular · Gene Expression Regulation · Glycoproteins · In Vitro · Lymphotoxin · Male · Plasminogen Inactivators · Rats · Rats, Inbred Strains · RNA, Messenger · Support, Non-U.S. Gov't · Tissue Plasminogen Activator · Tumor Necrosis Factor
[Abstract]

15 The influence of radiotherapy and chemotherapy on the vitamin status of cancer patients
article 1985    
Author: Schreurs, W.H.P. · Odink, J. · Egger, R.J. · Wedel, M. · Bruning, P.F.
Keywords: Antineoplastic agent · Bladder · Blood and hemopoietic system · Cancer combination chemotherapy · Clinical article · Drug efficacy · Hodgkin disease · Human · Intravenous drug administration · Male genital system · Priority journal · Therapy · Ascorbic Acid · Bladder Neoplasms · Calcifediol · Female · Human · Lymphoma · Male · Neoplasms · Prostatic Neoplasms · Uterine Neoplasms · Vitamin A · Vitamin B 12 · Vitamin E · Vitamins
[Abstract]

16 Kinetics of the formation and removal of cisplatin-DNA adducts in blood cells and tumor tissue of cancer patients receiving chemotherapy: comparison with in vitro adduct formation
article 1990    
Author: Fichtinger-Schepman, A.M.J. · Velde van der - Visser, S.D. · Dijk van - Knijnenburg, H.C.M. · Oosterom, A.T. van · Baan, R.A. · Berends, F.
Keywords: Antineoplastic agent · Cisplatin · Endogenous compound · Adult · Blood cell · Cancer · Cancer chemotherapy · Clinical article · DNA adduct · DNA binding · Female · Human · Intravenous drug administration · Male · Priority journal · Adult · Cisplatin · Comparative Study · DNA · Female · Human · Infusions, Intravenous · Kinetics · Leukocytes · Male · Middle Age · Neoplasms · Reference Values · Support, Non-U.S. Gov't · Time Factors
[Abstract]

17 Pharmacodynamics of cisplatin in human head and neck cancer : correlation between platinum content, DNA adduct levels and drug sensitivity in vitro and in vivo
article 1999    
Author: Welters, M.J.P. · Fichtinger-Schepman, A.M.J. · Baan, R.A. · Jacobs-Bergmans, A.J. · Kegel, A. · Vijgh, W.J.F. van der · Braakhuis, B.J.M.
Keywords: Cisplatin · Cisplatin sensitivity · DNA adducts · Head and neck cancer · Platinum accumulation · DNA · phosphorus 32 · platinum · animal experiment · animal tissue · atomic absorption spectrometry · cancer cell culture · controlled study · DNA drug complex · drug sensitivity · human cell · intravenous drug administration · mouse · nonhuman · nude mouse · pharmacodynamics · radioassay · squamous cell carcinoma · tumor xenograft · Animals · Antineoplastic Agents · Carcinoma, Squamous Cell · Drug Screening Assays, Antitumor · Female · Head and Neck Neoplasms · Humans · Mice · Mice, Nude · Neoplasm Transplantation · Tumor Cells, Cultured
[PDF] [Abstract]

18 Lung damage in the rat after irradiation and treatment with cytotoxic drugs
article 1986    
Author: Varekamp, A.E. · Vries, A.J. de · Hagenbeek, A.
Keywords: cyclophosphamide · cytarabine · cytotoxic agent · animal experiment · animal model · drug cytotoxicity · drug efficacy · histology · interstitial pneumonia · intoxication · intraperitoneal drug administration · intravenous drug administration · irradiation · lung function · lung injury · methodology · nonhuman · radiation injury · respiratory system · breathing · drug effect · LD 50 · pathophysiology · radiation exposure · radiation response · rat strain · Animal · Cyclophosphamide · Cytarabine · Dose-Response Relationship, Drug · Dose-Response Relationship, Radiation · Female · Lethal Dose 50 · Lung · Rats · Rats, Inbred Strains · Respiration
[PDF] [Abstract]

19 Thrombolytic properties in a rabbit jugular vein thrombosis model of a tissue-type plasminogen activator mutant lacking the growth factor- and kringle 1-domains
article 1992    
Author: Emeis, J.J. · Verheijen, J.H.
Keywords: Biology · Alpha 2 antiplasmin · Alteplase · Fk 2p · Gowth factor · Plasminogen · Unclassified drug · Animal experiment · Animal model · Blood clot lysis · Conference paper · Dose response · Dose time effect relation · Drug efficacy · Fibrinogen blood level · Intravenous drug administration · Mutant · Nonhuman · Protein domain · Spectrophotometry · Vein thrombosis · Animal · Comparative Study · Fibrinolysis · Infusions, Intravenous · Injections, Intravenous · Jugular Veins · Metabolic Clearance Rate · Rabbits · Recombinant Proteins · Thrombosis · Tissue Plasminogen Activator · Animalia · Oryctolagus cuniculus
[Abstract]

20 Therapy of organophosphate poisoning in the rat by direct effects of oximes unrelated to ChE reactivation
article 1991    
Author: Helden, H.P.M. van · Lange, J. de · Busker, R.W. · Melchers, B.P.C.
Keywords: Biology · Acetylcholinesterase · Direct effect · HGG-12 · HI-6 · Obidoxime · Organophosphate poisoning · P2S · 1 (4 carbamoylpyridinio) 1' (2 hydroxyiminomethylpyridinio)dimethyl ether · [(3 benzoyl 1 pyridiniomethyl) (2 hydroxyiminomethyl 1 pyridiniomethyl)] ether · Obidoxime · Organophosphate · Oxime · Soman · Animal experiment · Animal tissue · Diaphragm · Enzyme inhibition · Enzyme reactivation · Intravenous drug administration · Male · Nonhuman · Priority journal · Rat · Animal · Antidotes · Blood-Brain Barrier · Cholinesterase Reactivators · Diaphragm · In Vitro · Male · Neuromuscular Junction · Obidoxime Chloride · Organophosphorus Compounds · Oximes · Pralidoxime Compounds · Pyridinium Compounds · Rats · Respiratory Insufficiency · Synaptic Transmission · Animalia
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 34 found. Next | Sort by date