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Showing 1 to 18 of 18 found. | Sort by date

1 Lipoxygenase-2 oxygenates storage lipids in embryos of germinating barley
article 1997    
Author: Holtman, W.L. · Vredenbregt-Heistek, J.C. · Schmitt, N.F. · Feussner, I.
Keywords: Barley · Lipoxygenase isoenzyme · Oxygenation · Storage lipid · Isoenzyme · Lipoxygenase · Enzyme activity · Enzyme specificity · Germination · High performance liquid chromatography · Lipid oxidation · Phytochemistry · Priority journal · Chromatography, High Pressure Liquid · Germination · Hordeum · Isoenzymes · Kinetics · Lipid Metabolism · Lipids · Lipoxygenase · Substrate Specificity · Hordeum vulgare subsp. vulgare
[Abstract]

2 Kinetic characteristics of acidic and alkaline ceramidase in human epidermis
article 2007    
Author: Houben, E. · Uchida, Y. · Nieuwenhuizen, W.F. · Paepe, K. de · Vanhaecke, T. · Holleran, W.M. · Rogiers, V.
Keywords: Nutrition · Food technology · Ceramidase · Epidermis · Kinetic parameters · acylsphingosine deacylase · enzyme inhibitor · ethanolamine derivative · isoenzyme · adult · article · enzyme activity · enzyme analysis · enzyme assay · enzyme inhibition · enzyme kinetics · enzyme substrate · enzymology · epidermis · female · human · human tissue · isoenzyme analysis · isotope labeling · normal human · nucleotide sequence · priority journal · zymography · Adult · Amidohydrolases · Enzyme Repression · Epidermis · Female · Humans · Hydrogen-Ion Concentration · Isoenzymes · Kinetics · Middle Aged · Skin Absorption
[Abstract]

3 Enzyme kinetics and substrate selectivities of rat glutathione S-transferase isoenzymes towards a series of new 2-substituted 1-chloro-4-nitrobenzenes
article 1996    
Author: Aar, E.M. van der · Buikema, D. · Commandeur, J.N.M. · Koppele, J.M. te · Ommen, B. van · Bladeren, P.J. van · Vermeulen, N.P.E.
Keywords: Nutrition · glutathione transferase · isoenzyme · nitrobenzene derivative · animal tissue · article · controlled study · enzyme kinetics · enzyme specificity · glutathione metabolism · nonhuman · rat · Animals · Chromatography, Affinity · Dinitrochlorobenzene · Glutathione Transferase · Isoenzymes · Kidney · Kinetics · Liver · Rats · Spectrophotometry, Ultraviolet · Substrate Specificity · Animalia · Felis catus
[Abstract]

4 Intolerance to dietary biogenic amines: A review
article 2003    
Author: Jansen, S.C. · Dusseldorp, M. van · Bottema, K.C. · Dubois, A.E.J.
Keywords: Biology Nutrition · Food and Chemical Risk Analysis · amine oxidase (copper containing) · amine oxidase (flavin containing) isoenzyme A · amine oxidase (flavin containing) isoenzyme B · aryl sulfotransferase · biogenic amine · histamine · histamine methyltransferase · phenethylamine · tyramine · cacao · clinical article · clinical trial · controlled clinical trial · controlled study · correlation analysis · diet · double blind procedure · evidence based medicine · food allergy · food intake · headache · human · medical literature · migraine · nutritional intolerance · priority journal · provocation test · publication · randomized controlled trial · review · treatment outcome · urticaria · wine · Administration, Oral · Adult · Biogenic Amines · Cacao · Child · Clinical Trials · Diagnostic Errors · Diet · Food Hypersensitivity · Headache · Histamine · Humans · Migraine Disorders · Phenethylamines · Research Design · Tyramine · Wine
[Abstract]

5 Inhibition of human glutathione S-transferase P1-1 by the flavonoid quercetin
article 2003    
Author: Zanden, J.J. van · Hamman, O.B. · Iersel, M.L.P.S. van · Boeren, S. · Cnubben, N.H.P. · Lo Bello, M. · Vervoort, J. · Bladeren, P.J. van · Rietjens, I.M.C.M.
Keywords: Biology · Physiological Sciences · Cysteine · Glutathione S-transferase · Inhibition · Quercetin · Quinone · ascorbic acid · cysteine · flavonoid · glutathione · glutathione transferase · isoenzyme · mutant protein · quercetin · article · chemical interaction · concentration response · covalent bond · dimerization · enzyme inhibition · human · incubation time · inhibition kinetics · time · Chromatography, High Pressure Liquid · Dose-Response Relationship, Drug · Glutathione Transferase · Humans · Mass Spectrometry · Molecular Structure · Monophenol Monooxygenase · Mutation · Quercetin
[Abstract]

6 Effect of fumonisin B1 on rat hepatic P450 system
article 2000    
Author: Spotti, M. · Maas, R.F.M. · Nijs, C.M. de · Fink-Gremmels, J.
Keywords: Nutrition · Cytochrome P450 · Fumonisin B1 · Liver · Rat · Cytochrome P450 3A · Dimethylnitrosamine demethylase · Fumonisin B1 · Isoenzyme · Pentoxyresorufin dealkylase · Phenacetin o deethylase · Protein kinase · Sphingolipid · Animal model · Body weight · Controlled study · Enzyme activity · Growth retardation · Male · Metabolism · Nonhuman · Oral drug administration · Priority journal · Rat
[Abstract]

7 Characterization of cytochrome P450 isoenzymes in primary cultures of pig hepatocytes
article 1998    
Author: Monshouwer, M. · Klooster, G.A.E. van 't · Nijmeijer, S.M. · Witkamp, R.F. · Miert, A.S.J.P.A.M. van
Keywords: Nutrition · Cytochrome P450 · Hepatocytes · Induction · Pig · Apoprotein · Beta naphthoflavone · Complementary DNA · Cytochrome p450 isoenzyme · Dexamethasone · Ethoxyresorufin deethylase · Ethylmorphine n demethylase · Messenger RNA · Oxygenase · Phenobarbital · Rifampicin · Animal cell · Controlled study · Enzyme activity · Enzyme analysis · Enzyme induction · Liver cell culture · Nonhuman · RNA analysis · RNA hybridization · Swine · Xenobiotic metabolism
[Abstract]

8 Investigating the role of natural phyto-oestrogens on bone health in postmenopausal women
article 2003    
Author: Valtueña, S. · Cashman, K. · Robins, S.P. · Cassidy, A. · Kardinaal, A. · Branca, F.
Keywords: Health Biology · Physiological Sciences · Clinical trials · Isoflavones · Menopause · acid phosphatase tartrate resistant isoenzyme · alkaline phosphatase bone isoenzyme · biochemical marker · collagen aminopeptide · collagen c peptide · collagen derivative · deoxypyridinoline · isoflavone · osteocalcin · phytoestrogen · procollagen c propeptide · procollagen n propeptide · pyridinoline · sialoprotein · soybean protein · unclassified drug · estrogen · isoflavone derivative · plant medicinal product · bone density · bone metabolism · bone mineral · bone remodeling · bone strength · bone turnover · clinical trial · diet supplementation · diet therapy · dietary intake · evidence based medicine · genetic variability · human · medical decision making · menopausal syndrome · nonhuman · ossification · osteoporosis · outcomes research · patient compliance · patient monitoring · patient selection · physical activity · postmenopause · review · short course therapy · chemistry · controlled clinical trial · diet · female · methodology · middle aged · postmenopause osteoporosis · randomized controlled trial · soybean · treatment outcome · Glycine max · Diet · Estrogens, Non-Steroidal · Female · Humans · Isoflavones · Middle Aged · Osteoporosis, Postmenopausal · Phytoestrogens · Plant Preparations · Randomized Controlled Trials · Research Design · Soybeans · Treatment Outcome
[PDF] [Abstract]

9 Two novel, putatively cell wall-associated and glycosylphosphatidylinositol-anchored α-glucanotransferase enzymes of Aspergillus niger
article 2007    
Author: Kaaij, R.M. van der · Yuan, X.L. · Franken, A. · Ram, A.F.J. · Punt, P.J. · Maarel, M.J.E.C. van der · Dijkhuizen, L.
Keywords: Biology · Food technology · 4 alpha glucanotransferase · 4 alpha-glucanotransferase · fungal protein · glycogen debranching enzyme · glycosylphosphatidylinositol · hybrid protein · isoenzyme · maltooligosaccharides · oligosaccharide · unclassified drug · amino acid sequence · article · Aspergillus niger · cell wall · chemistry · classification · cytology · enzymology · genetics · metabolism · molecular genetics · nucleotide sequence · phylogeny · sequence alignment · sequence homology · Amino Acid Sequence · Aspergillus niger · Base Sequence · Cell Wall · Fungal Proteins · Glycogen Debranching Enzyme System · Glycosylphosphatidylinositols · Isoenzymes · Molecular Sequence Data · Oligosaccharides · Phylogeny · Recombinant Fusion Proteins · Sequence Alignment · Sequence Homology, Amino Acid · Aspergillus niger
[Abstract]

10 The biotransformation of isoprene and the two isoprene monoepoxides by human cytochrome P450 enzymes, compared to mouse and rat liver microsomes
article 1996    
Author: Bogaards, J.J.P. · Venekamp, J.C. · Bladeren, P.J. van
Keywords: Cytochrome P-450 · Isoprene · Metabolism · cyclohexane oxide · cytochrome p450 · cytochrome p450 isoenzyme · epoxide hydrolase · isoprene · animal experiment · article · controlled study · enzyme activity · enzyme specificity · epoxidation · human · human tissue · liver microsome metabolism · mouse · nonhuman · rat · species difference · xenobiotic metabolism · Animals · Biotransformation · Butadienes · Cyclohexanes · Cyclohexenes · Cytochrome P-450 CYP2E1 · Cytochrome P-450 Enzyme System · Enzyme Inhibitors · Epoxide Hydrolases · Epoxy Compounds · Hemiterpenes · Humans · Hydrolysis · Mice · Microsomes, Liver · Oxidation-Reduction · Pentanes · Rats · Rats, Wistar · Species Specificity
[Abstract]

11 In vitro inhibition of rat and human glutathione S-transferase isoenzymes by disulfiram and diethyldithiocarbamate
article 1996    
Author: Ploemen, J.-P.H.T.M. · Iersel, M.L.P.S. van · Wormhoudt, L.W. · Commandeur, J.N.M. · Vermeulen, N.P.E. · Bladeren, P.J. van
Keywords: diethyldithiocarbamate · disulfiram · gl utathion e · glutathione S-transferases · in vitro · inhibition · 1 chloro 2,4 dinitrobenzene · 1,2 epoxy 3 (4 nitrophenoxy)propane · aldehyde dehydrogenase inhibitor · diethyldithiocarbamic acid · disulfiram · dithiothreitol · glutathione transferase · isoenzyme · thiol · unclassified drug · article · controlled study · drug metabolism · enzyme inactivation · enzyme inhibition · enzyme purification · enzyme substrate · human · nonhuman · priority journal · rat · reduction · Animals · Disulfiram · Dithiothreitol · Ditiocarb · Glutathione · Glutathione Transferase · Humans · Isoenzymes · Rats · Spectrophotometry, Ultraviolet · Time Factors
[Abstract]

12 Interactions of prostaglandin A2 with the glutathione-mediated biotransformation system
article 1999    
Author: Iersel, M.L.P.S. van · Cnubben, N.H.P. · Smink, N. · Koeman, J.H. · Bladeren, P.J. van
Keywords: Nutrition · Cells · Glutathione S-transferases · Inhibition · Metabolism · Prostaglandin A2 · 1 chloro 2,4 dinitrobenzene · Glutathione · Glutathione transferase · Prostaglandin a2 · Glutathione transferase P1 · GSTP1 protein, human · Isoenzyme · Prostaglandin A · Prostaglandin A2 · Biotransformation · Cell function · Cell metabolism · Cell proliferation · Controlled study · Cytotoxicity · Enzyme activity · Enzyme modification · Human · Human cell · Melanoma cell · Priority journal · Cell culture · Drug antagonism · Melanoma · Metabolism · Biotransformation · Glutathione · Glutathione S-Transferase pi · Glutathione Transferase · Humans · Isoenzymes · Melanoma · Prostaglandins A · Tumor Cells, Cultured
[Abstract]

13 Isolation and molecular characterisation of the gene encoding eburicol 14α-demethylase (CYP51) from Penicillium italicum
article 1996    
Author: Nistelrooy, J.G.M. van · Brink, J.M. van den · Kan, J.A.L. van · Gorcom, R.F.M. van · Waard, M.A. de
Keywords: Biology · 14α-demethylase · Cytochrome P450 · Fungicides · Penicillium italicum · Sterol biosynthesis inhibitors · Cytochrome p450 isoenzyme · Enilconazole · Etaconazole · Fenarimol · Fungicide · Unclassified drug · Article · Controlled study · Gene isolation · Genetic analysis · Molecular cloning · Molecular genetics · Nonhuman · Penicillium · Priority journal · Sterol synthesis · Yeast · Amino Acid Sequence · Base Sequence · Blotting, Northern · Cloning, Molecular · Cytochrome P-450 Enzyme System · DNA Primers · Fungal Proteins · Fungicides, Industrial · Genes, Fungal · Lanosterol · Molecular Sequence Data · Oxidoreductases · Penicillium · Pyrimidines · Restriction Mapping · Sequence Analysis, DNA · Sequence Homology, Amino Acid
[Abstract]

14 Hepatic epoxide concentrations during biotransformation of 1,2- and 1,4- dichlorobenzene: The use of in vitro and in vivo metabolism, kinetics and PB- PK modeling
article 1996    
Author: Hissink, E. · Ommen, B. van · Bogaards, J.J. · Bladeren, P.J. van
Keywords: Toxicology · 1,2 dichlorobenzene · 1,4 dichlorobenzene · alanine aminotransferase · ascorbic acid · cytochrome p450 isoenzyme · epoxide · glutathione · isoniazid · animal cell · animal experiment · animal model · biotransformation · conference paper · controlled study · detoxification · enzyme substrate · liver microsome · liver toxicity · male · mathematical model · nonhuman · priority journal · rat · toxicokinetics · Animals · Biotransformation · Carcinogens · Chlorobenzenes · Cytochrome P-450 Enzyme System · Epoxy Compounds · Humans · Liver · Male · Microsomes, Liver · Models, Biological · Rats · Rats, Wistar

15 Erosive arthritis in a patient with pycnodysostosis: An experiment of nature
article 2008    
Author: Ainola, M. · Valleala, H. · Nykänen, P. · Risteli, J. · Hanemaaijer, R. · Konttinen, Y.T.
Keywords: Health · acid phosphatase tartrate resistant isoenzyme · calcitonin receptor · carboxy terminal telopeptide · cathepsin K · folic acid · hydroxychloroquine · ketoprofen · matrix metalloproteinase · messenger RNA · methotrexate · n [n (3 carboxyoxirane 2 carbonyl)leucyl]agmatine · prednisolone · salazosulfapyridine · adult · article · bone defect · bone erosion · case report · collagen degradation · controlled study · drug withdrawal · dysostosis · female · hand radiography · human · human cell · monocyte · multinuclear cell · nucleotide sequence · osteoclast · osteolysis · priority journal · psoriatic arthritis · pyknodysostosis · rash · synovitis · Acid Phosphatase · Arthritis, Psoriatic · Bone Resorption · Cathepsins · Cells, Cultured · Dysostoses · Female · Humans · Middle Aged · Monocytes · Osteoclasts · Receptors, Calcitonin
[Abstract]

16 Microdosing of a Carbon-14 Labeled Protein in Healthy Volunteers Accurately Predicts Its Pharmacokinetics at Therapeutic Dosages
article 2015    
Author: Vlaming, M.L. · Duijn, E. van · Dillingh, M.R. · Brands, R. · Windhorst, A.D. · Hendrikse, N.H. · Bosgra, S. · Burggraaf, J. · Koning, M.C. de · Fidder, A. · Mocking, J.A. · Sandman, H. · Ligt, R.A. de · Fabriek, B.O. · Pasman, W.J. · Seinen, W. · Alves, T. · Carrondo, M. · Peixoto, C. · Peeters, P.A. · Vaes, W.H.
Keywords: Biology · Alkaline phosphatase, placental · Carbon · Glycosylphosphatidylinositol anchored protein · Isoenzyme · Recombinant protein · Area under the curve · Biological model · Clinical trial · Controlled study · Dose calculation · Double blind procedure · Half life time · Intravenous drug administration · Phase 1 clinical trial · Procedures · Randomized controlled trial · Statistical model · Administration, Intravenous · Adolescent · Adult · Alkaline Phosphatase · Area Under Curve · Carbon Radioisotopes · Double-Blind Method · Drug Dosage Calculations · GPI-Linked Proteins · Half-Life · Healthy Volunteers · Humans · Isoenzymes · Linear Models · Male · Mass Spectrometry · Metabolic Clearance Rate · Models, Biological · Netherlands · Recombinant Proteins · Young Adult · Biomedical Innovation · Healthy Living · Life Triskelion BV · MSB - Microbiology and Systems Biology ARPC - Analytical Research (Pharm & Chemistry) · ELSS - Earth, Life and Social Sciences TNO Bedrijven
[Abstract]

17 In vitro and in vivo inhibition of human flavin-containing monooxygenase form 3 (FMO3) in the presence of dietary indoles
article 1999    
Author: Cashman, J.R. · Xiong, Y. · Lin, J. · Verhagen, H. · Poppel, G. van · Bladeren, P.J. van · Larsen-Su, S. · Williams, D.E.
Keywords: Nutrition · Dietary indoles · Human flavin-containing monooxygenase · Indole-3-carbinol-related inhibitors · Trimethylamine N-oxygenation inhibitors · 3 indolemethanol · Complementary DNA · Flavin containing monooxygenase 3 · Glucosinolate · Hydrochloric acid · Indole derivative · Isoenzyme · Trimethylamine · Trimethylamine oxide · Unclassified drug · Unspecific monooxygenase · Adult · Controlled study · Dietary intake · Enzyme activity · Enzyme inhibition · Gas chromatography · Gastrointestinal tract · High performance liquid chromatography · Human · Human experiment · Male · Mass spectrometry · Normal human · Oral drug administration · Polymerization · Priority journal · Volunteer · Xenobiotic metabolism · Adult · Antioxidants · Brassica · Carrier Proteins · Cross-Over Studies · Diet · Humans · Indoles · Male · Methylamines · Oxygenases
[Abstract]

18 Cholesterol 7α-Hydroxylase Deficiency in Mice on an APOE*3-Leiden Background Impairs Very-Low-Density Lipoprotein Production
article 2004    
Author: Post, S.M. · Groenendijk, M. · Solaas, K. · Rensen, P.C.N. · Princen, H.M.G.
Keywords: Biology · Biomedical Research · Bile acid biosynthesis · Cholesterol 7α-hydroxylase · SREBP-1 · Bile acid · Cholesterol · Cholesterol 7alpha monooxygenase · Cholesterol ester · Cytochrome P450 isoenzyme · Messenger RNA · Sterol · Sterol regulatory element binding protein 1 · Unclassified drug · Very low density lipoprotein · Vitamin · Acyltransferase · Alpha tocopherol · Apolipoprotein E3 (Leidein) · Dgat1 protein, mouse · Diacylglycerol acyltransferase · Retinol · Animal experiment · Animal model · Animal tissue · Antioxidant activity · Bile acid synthesis · Catalysis · Cholesterol blood level · Cholesterol metabolism · Controlled study · Enzyme deficiency · Feces level · Gene · Gene expression · Hyperlipidemia · Knockout mouse · Lipid diet · Lipid metabolism · Lipogenesis · Lipoprotein synthesis · Nonhuman · Srebf1 gene · Triacylglycerol blood level · Atherogenic diet · Biosynthesis · Blood · Cross breeding · Feces · Genetics · Metabolism · Mouse mutant · Physiology · Acyltransferases · Animals · Apolipoprotein E3 · Apolipoproteins B · Apolipoproteins E · Bile Acids and Salts · Cholesterol 7-alpha-Hydroxylase · Cholesterol Esters · Crosses, Genetic · Diacylglycerol O-Acyltransferase · Diet, Atherogenic · Feces · Female · Hyperlipoproteinemia Type III · Ketone Bodies · Lipid Metabolism · Lipolysis · Lipoproteins, VLDL · Liver · Male · Mice · Mice, Knockout · RNA, Messenger · Sterols · Triglycerides · Vitamin A · Vitamin E
[Abstract]

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Showing 1 to 18 of 18 found. | Sort by date