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1 Partial characterization of low density lipoprotein preparations isolated from fresh and frozen plasma after radiolabeling by seven different methods
article 1991    
Author: Atsma, D.E. · Kempen, H.J.M. · Nieuwenhuizen, W. · Hooft, F.M. van 't · Pauwels, E.K.J.
Keywords: Biology · Animal · Chromatography, Gel · Electrophoresis, Agar Gel · Evaluation Studies · Human · Iodine Radioisotopes · Isotope Labeling · Lipoproteins, LDL · Male · Rabbits · Technetium
[PDF] [Abstract]

2 Water-soluble vitamins and flavonoids - Summary
article 1997    
Author: Berg, H. van den
Keywords: Nutrition · Bioavailability · Flavonoids · Methodology · Water-soluble vitamins · Flavonoid · Vitamin · Bioavailability · Conference paper · Dietary intake · Human · Intestine absorption · Isotope labeling · Urinary excretion · Vitamin intake · Vitamin metabolism

3 A new method to measure iron absorption from the enrichment of 57Fe and 58Fe in young erythroid cells
article 1998    
Author: Heuvel, E.G.H.M. van den · Muys, T. · Pellegrom, H. · Bruyntjes, J.P. · Dokkum, W. van · Spanhaak, S. · Schaafsma, G.
Keywords: Nutrition · Iron · Adult · Cell membrane transport · Controlled study · Erythroid cell · Female · Human · Human cell · Iron absorption · Iron kinetics · Isotope labeling · Normal human · Radioisotope distribution · Absorption · Administration, Oral · Adult · Cell Separation · Centrifugation, Zonal · Erythrocyte Aging · Erythrocytes · Female · Ferritins · Humans · Injections, Intravenous · Iron · Iron Isotopes · Isotope Labeling · Mass Spectrometry · Reticulocytes
[Abstract]

4 The determination of exogenous formaldehyde in blood of rats during and after inhalation exposure
article 2013    
Author: Kleinnijenhuis, A.J. · Staal, Y.C.M. · Duistermaat, E. · Engel, R. · Woutersen, R.A.
Keywords: Health · 13C-formaldehyde · HPLC-MS analysis in blood · Inhalation study · Stable isotope labeling · Biomedical Innovation · Healthy Living · Life Triskelion BV · QS - Quality & Safety RAPID - Risk Analysis for Products in Development ARPC - Analytical Research (Pharm & Chemistry) TARA - Toxicology and Risk Assessment · EELS - Earth, Environmental and Life Sciences TNO Bedrijven
[Abstract]

5 The ultimate radiochemical nightmare : upon radio-iodination of Botulinum neurotoxin A, the introduced iodine atom itself seems to be fatal for the bioactivity of this macromolecule
article 2015    
Author: Uhm, J.I.M. van · Visser, G.W.M. · Schans, M.J. van der · Geldof, A.A. · Meuleman, E.J.H. · Nieuwenhuijzen, J.A.
Keywords: Botulinum neurotoxin A · Iodine-125 · Monoclonal antibody · PET research · Radio-iodination · Botulinum toxin A · Cetuximab · Cetuximab i 125 · Radiopharmaceutical agent · Unclassified drug · Biological activity · Controlled study · Drug purity · Gel permeation chromatography · High performance liquid chromatography · Human cell · Immunoreactivity · Iodination · Isotope labeling · Luminescence · Radioactivity · Radiochemistry · Reaction time · Thin layer chromatography · Observation, Weapon & Protection Systems · CBRN - CBRN Protection · TS - Technical Sciences
[PDF] [Abstract]

6 Nondigestible oligosaccharides do not interfere with calcium and nonheme-iron absorption in young, healthy men
article 1998    
Author: Heuvel, E.G.H.M. van den · Schaafsma, G. · Muys, T. · Dokkum, W. van
Keywords: Nutrition · Absorption · Calcium · Fructooligosaccharide · Galactooligosaccharide · Inulin · Iron · Men · Nondigestible oligosaccharides · S table isotopes · calcium · fructose oligosaccharide · inulin · iron · oligosaccharide · adult · article · carbohydrate diet · clinical trial · controlled study · crossover procedure · erythrocyte · human · human experiment · intestine absorption · iron absorption · isotope labeling · male · normal human · randomized controlled trial · urinary excretion · Adult · Biological Availability · Calcium · Calcium Isotopes · Humans · Intestinal Absorption · Iron · Iron Isotopes · Male · Oligosaccharides
[Abstract]

7 Differences in metabolism and isomerization of all-trans-retinoic acid and 9-cis-retinoic acid between human endothelial cells and hepatocytes
article 1997    
Author: Lansink, M. · Bennekum, A.M. van · Blaner, W.S. · Kooistra, T.
Keywords: Health · Human endothelial cell · Human hepatocyte · Isomerization · Metabolism · Liarozole · Plasminogen activator · Retinoic acid · Cell culture · Controlled study · Drug metabolism · Endothelium cell · High performance liquid chromatography · Human cell · In vitro study · Isomerism · Isotope labeling · Liver cell culture · Lliver metabolism · Biotransformation · Cells, Cultured · Chromatography, High Pressure Liquid · Endothelium, Vascular · Humans · Isomerism · Kinetics · Liver · Tretinoin · Umbilical Veins
[Abstract]

8 Low-density lipoproteins are degraded in HepG2 cells with low efficiency
article 1993    
Author: Lombardi, P. · Mulder, M. · Wit, E. de · Berkel, T.J.C. van · Frants, R.R. · Havekes, L.M.
Keywords: Low density lipoprotein · Low density lipoprotein receptor · Cell density · Cell fractionation · Comparative study · Density gradient centrifugation · Endosome · Hepatoma cell · Human cell · Internalization · Isotope labeling · Lipoprotein metabolism · Protein degradation · Receptor down regulation · Biological Transport · Cell Aggregation · Cell Line · Cells, Cultured · Down-Regulation · Fibroblasts · Human · Iodine Radioisotopes · Kinetics · Lipoproteins, LDL · Liver · Lysosomes · Receptors, LDL · Support, Non-U.S. Gov't
[Abstract]

9 Bioavailability of calcium and magnesium
article 1997    
Author: Schaafsma, G.
Keywords: Dietary factors · Intestinal absorption · Methodology · Bioavailability · Bone mass · Calcium absorption · Calcium intake · Calcium transport · Calcium urine level · Conference paper · Dietary intake · Dual energy X ray absorptiometry · Intestine absorption · Isotope labeling · Lactation · Magnesium blood level · Osteoporosis · Pregnancy · Absorption · Animals · Biological Availability · Calcium · Humans · Intestinal Absorption · Kidney · Magnesium
[Abstract]

10 Does loading influence the severity of cartilage degeneration in the canine groove-model of OA?
article 2009    
Author: Vos, P. · Intema, F. · El, B. van · Groot, J. de · Bijlsma, J.W.J. · Lafeber, F. · Mastbergen, S.
Keywords: Canine · Cartilage · Groove-model · Loading · Osteoarthritis · DNA · Cartilage degeneration · Enzyme activity · Femur condyle · Histology · Inflammation · Isotope labeling · Knee osteoarthritis · Leg exercise · Loading test · Osteoarthritis · Synovium · Tibia · Animals · Collagen · Disease Progression · Dogs · Physical Conditioning, Animal · Proteoglycans · Severity of Illness Index · Synovial Membrane · Weight-Bearing
[Abstract]

11 Gaining Insight into Microbial Physiology in the Large Intestine: A Special Role for Stable Isotopes
article 2008    
Author: Graaf, A.A. de · Venema, K.
Keywords: Biology · Biomedical Research · Butyric acid · Prebiotic agent · Stable isotope · Bacterial phenomena and functions · Biomedicine · Ecosystem · Energy balance · Genome · Genomics · Immune system · Innate immunity · Intestine flora · Large intestine · Metabolic stress · Metabolomics · Microbial metabolism · Microorganism · Nonhuman · Obesity · PH · Proteomics · Review · Bacterial Physiology · Fatty Acids, Volatile · Genomics · Humans · Intestine, Large · Isotope Labeling · Proteomics · Radioisotopes · Radiopharmaceuticals
[Abstract]

12 Kinetic characteristics of acidic and alkaline ceramidase in human epidermis
article 2007    
Author: Houben, E. · Uchida, Y. · Nieuwenhuizen, W.F. · Paepe, K. de · Vanhaecke, T. · Holleran, W.M. · Rogiers, V.
Keywords: Nutrition · Food technology · Ceramidase · Epidermis · Kinetic parameters · acylsphingosine deacylase · enzyme inhibitor · ethanolamine derivative · isoenzyme · adult · article · enzyme activity · enzyme analysis · enzyme assay · enzyme inhibition · enzyme kinetics · enzyme substrate · enzymology · epidermis · female · human · human tissue · isoenzyme analysis · isotope labeling · normal human · nucleotide sequence · priority journal · zymography · Adult · Amidohydrolases · Enzyme Repression · Epidermis · Female · Humans · Hydrogen-Ion Concentration · Isoenzymes · Kinetics · Middle Aged · Skin Absorption
[Abstract]

13 Comparative in vitro-in vivo percutaneous absorption of the pesticide propoxur
article 2000    
Author: Sandt, J.J.M. van de · Meuling, W.J.A. · Elliott, G.R. · Cnubben, N.H.P. · Hakkert, B.C.
Keywords: Nutrition · Human · In vitro/in vivo comparisons · Perfused-pig-ear model · Propoxur · Rat · Viable skin and epidermal membranes · Carbon 14 · Pesticide · Propoxur · Animal model · Animal tissue · Blood sampling · Ear · Environmental exposure · Epidermis · Human · Human experiment · Human tissue · Isotope labeling · Nonhuman · Normal human · Pest control · Rat · Skin absorption · Swine · Urinalysis · Animal Testing Alternatives · Animals · Ear, External · Epidermis · Humans · Insecticides · Male · Models, Animal · Perfusion · Propoxur · Rats · Rats, Wistar · Skin Absorption · Species Specificity · Swine · Animalia · Sus scrofa
[Abstract]

14 Human granzyme B mediates cartilage proteoglycan degradation and is expressed at the invasive front of the synovium in rheumatoid arthritis
article 2001    
Author: Ronday, H.K. · Laan, W.H. van der · Tak, P.P. · Roos, J.A.D.M. de · Bank, R.A. · Tekoppele, J.M. · Froelich, C.J. · Hack, C.E. · Hogendoorn, P.C.W. · Breedveld, F.C. · Verheijen, J.H.
Keywords: Biology Health · Biomedical Research · Cartilage destruction · Granzyme B · Rheumatoid arthritis · collagen · glycosaminoglycan · granzyme B · hydroxyproline · proline · proteoglycan · sulfate · sulfur 35 · tritium · animal tissue · bone erosion · cartilage degeneration · cartilage matrix · collagen degradation · controlled study · explant · human cell · immunohistochemistry · isotope labeling · joint destruction · nonhuman · priority journal · protein denaturation · protein expression · proteoglycan synthesis · rheumatoid arthritis · synovium · Animals · Arthritis, Rheumatoid · Cartilage · Cattle · Cells, Cultured · Chondrocytes · Collagen · Extracellular Matrix · Granzymes · Humans · Metacarpophalangeal Joint · Proteoglycans · Serine Endopeptidases · Synovial Membrane
[Abstract]

15 Comparison of immunoaffinity chromatography enrichment and nuclease P1 procedures for 32P-postlabelling analysis of PAH- DNA adducts
article 1998    
Author: Randerath, K. · Sriram, P. · Moorthy, B. · Aston, J.P. · Baan, R.A. · Berg, P.T.M. van den · Booth, E.D. · Watson, W.P.
Keywords: Nutrition · 32P-postlabelling · DNA adducts · Immunoaffinity · Nuclease P1 · PAH · Nuclease · Phosphorus 32 · Polycyclic aromatic hydrocarbon · Adsorption · Animal cell · Column chromatography · Contamination · Dna adduct · Enzyme analysis · Enzyme specificity · Genotoxicity · Immunoaffinity chromatography · Mutagenicity · Nonhuman · Protein modification · 9,10-Dimethyl-1,2-benzanthracene · Animals · Antibodies, Monoclonal · Aspergillus Nuclease S1 · Benzo(a)pyrene · Carcinogens · Chromatography, Affinity · Chrysenes · DNA Adducts · Fluorescent Antibody Technique · Isotope Labeling · Mice · Mutagenicity Tests · Mutagens · Phosphorus Radioisotopes · Polycyclic Hydrocarbons, Aromatic · Skin · Animalia
[Abstract]

16 Potential of 99mTc-LDLs labeled by two different methods for scintigraphic detection of experimental atherosclerosis in rabbits
article 1993    
Author: Atsma, D.E. · Feitsma, R.I.J. · Camps, J. · Hooft, F.M. van 't · Wall, E.E. van der · Nieuwenhuizen, W. · Pauwels, E.K.J.
Keywords: Biology · LDL · Rradiolabeling · Scintigraphy · Dithionite · Low density lipoprotein · Sodium borohydride · Stannous chloride · Technetium 99m · Borane derivative · Borohydride potassium · Diagnostic agent · Technetium complex · Technetium Tc 99m low density lipoprotein · Technetium Tc 99m low-density lipoprotein · Abdominal aorta · Animal experiment · Animal model · Animal tissue · Clearance · Controlled study · Intermethod comparison · Isotope labeling · Scintiscanning · Thoracic aorta · Animal · Aorta · Arteriosclerosis · Borohydrides · Dithionite · Lipoproteins, LDL · Male · Organotechnetium Compounds · Rabbits · Support, Non-U.S. Gov't · Tin
[Abstract]

17 Transgalactooligosaccharides stimulate calcium absorption in postmenopausal women
article 2000    
Author: Heuvel, E.G.H.M. van den · Schoterman, M.H.C. · Muijs, T.
Keywords: Nutrition · Calcium absorption · Postmenopausal women · Stable isotopes · Transgalactooligosaccharides · Calcium · Oligosaccharide · Stable isotope · Bone metabolism · Calcium absorption · Calcium excretion · Clinical trial · Controlled clinical trial · Controlled study · Crossover procedure · Dietary intake · Double blind procedure · Female · Human · Human experiment · Isotope labeling · Normal human · Osteolysis · Postmenopause · Randomized controlled trial · Urinalysis · Administration, Oral · Aged · Calcium · Cross-Over Studies · Double-Blind Method · Female · Humans · Injections, Intravenous · Intestinal Absorption · Middle Aged · Oligosaccharides · Osteoporosis, Postmenopausal · Postmenopause · Radioactive Tracers · Spectrophotometry · Yogurt · Toscana virus
[Abstract]

18 Transdermal administration of radiolabelled [14C]rotigotine by a patch formulation: A mass balance trial
article 2007    
Author: Cawello, W. · Wolff, H.M. · Meuling, W.J.A. · Horstmann, R. · Braun, M.
Keywords: Biomedical Research · carbon 14 · dopamine receptor stimulating agent · rotigotine · silicone · adult · article · clinical trial · diarrhea · dizziness · drug absorption · drug clearance · drug delivery system · drug distribution · drug elimination · drug formulation · drug metabolism · drug penetration · drug release · drug structure · drug tolerability · fatigue · human · human experiment · isotope labeling · liquid chromatography · liquid scintillation counting · male · mass balance · normal human · phase 1 clinical trial · priority journal · radioactivity · single drug dose · tandem mass spectrometry · Administration, Cutaneous · Adolescent · Adult · Carbon Radioisotopes · Chromatography, Liquid · Dopamine Agonists · Humans · Male · Middle Aged · Tandem Mass Spectrometry · Tetrahydronaphthalenes · Thiophenes
[Abstract]

19 Disposition of 14C-α-cyclodextrin in germ-free and conventional rats
article 2004    
Author: Ommen, B. van · Bie, A.T.H.J. de · Bär, A.
Keywords: Biology · Physiological Sciences · alpha cyclodextrin · carbon 14 · alpha cyclodextrin derivative · alpha-cyclodextrin · carbon · cyclodextrin · animal experiment · animal tissue · article · blood analysis · carcass · controlled study · dietary fiber · female · fermentation · gastrointestinal tract · germfree animal · high performance liquid chromatography · intestine flora · isotope labeling · kidney tubule excretion · lung alveolus carbon dioxide tension · male · metabolic regulation · nonhuman · priority journal · radioisotope distribution · rat · rat strain · small intestine absorption · species comparison · stomach content · animal · blood · drug detoxification · intravenous drug administration · oral drug administration · tissue distribution · urine · Wistar rat · Mammalia · Microbiota · Rattus norvegicus · Administration, Oral · alpha-Cyclodextrins · Animals · Carbon Radioisotopes · Cyclodextrins · Female · Germ-Free Life · Injections, Intravenous · Male · Metabolic Detoxication, Drug · Rats · Rats, Wistar · Tissue Distribution
[Abstract]

20 Effect of methylglyoxal on the physico-chemical and biological properties of low-density lipoprotein
article 1998    
Author: Schalkwijk, C.G. · Vermeer, M.A. · Stehouwer, C.D.A. · Koppele, J. te · Princen, H.M.G. · Hinsbergh, V.W.M. van
Keywords: Biology · Advanced glycation end product · Diabetes · Low density lipoprotein · Methylglyoxal · Arginine · Cholesterol ester · Cytochrome c · Iodine 125 · Low density lipoprotein · Low density lipoprotein receptor · Lysine · Methylglyoxal · Monocyte chemotactic protein 1 · Oxidized low density lipoprotein · Superoxide · Vasculotropin · Controlled study · Fluorescence · Human · Human cell · Isotope labeling · Lipid metabolism · Macrophage · Plasma clearance · Priority journal · Receptor affinity · Animals · Cell Line · Chemistry, Physical · Cytochrome c Group · Electrochemistry · Endothelium, Vascular · Fibroblasts · Humans · Lipid Peroxidation · Lipid Peroxides · Lipoproteins, LDL · Macrophages · Malondialdehyde · Mice · Oxidation-Reduction · Pyruvaldehyde · Receptors, LDL · Superoxides · Thiobarbituric Acid Reactive Substances · Murinae
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 25 found. Next | Sort by date