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1 Characterization of cytochrome P450 isoenzymes in primary cultures of pig hepatocytes
article 1998    
Author: Monshouwer, M. · Klooster, G.A.E. van 't · Nijmeijer, S.M. · Witkamp, R.F. · Miert, A.S.J.P.A.M. van
Keywords: Nutrition · Cytochrome P450 · Hepatocytes · Induction · Pig · Apoprotein · Beta naphthoflavone · Complementary DNA · Cytochrome p450 isoenzyme · Dexamethasone · Ethoxyresorufin deethylase · Ethylmorphine n demethylase · Messenger RNA · Oxygenase · Phenobarbital · Rifampicin · Animal cell · Controlled study · Enzyme activity · Enzyme analysis · Enzyme induction · Liver cell culture · Nonhuman · RNA analysis · RNA hybridization · Swine · Xenobiotic metabolism
[Abstract]

2 In vitro liver models are important tools to monitor the abuse of anabolic steroids in cattle
article 1998    
Author: Puymbroeck, M. van · Kuilman, M.E.M. · Maas, R.F.M. · Witkamp, R.F. · Leyssens, T. · Zande, D.J.M. van der · Gelan, J. · Raus, J.
Keywords: Nutrition · Anabolic agent · Biological marker · Boldenone · Clostebol · Estrane derivative · Ethylestrenol · Norethandrolone · Steroid · Animal tissue · Cattle · Conference paper · Controlled study · Drug abuse · Drug determination · Drug metabolism · Drug monitoring · Female · Liver · Liver cell culture · Liver metabolism · Liver microsome · Male · Model · Nonhuman · Steroid metabolism · Anabolic Agents · Animals · Biological Markers · Cattle · Cells, Cultured · Drug Residues · Estradiol · Ethylestrenol · Liver · Microsomes, Liver · Models, Biological · Norethandrolone · Predictive Value of Tests · Testosterone
[PDF] [Abstract]

3 Differences in metabolism and isomerization of all-trans-retinoic acid and 9-cis-retinoic acid between human endothelial cells and hepatocytes
article 1997    
Author: Lansink, M. · Bennekum, A.M. van · Blaner, W.S. · Kooistra, T.
Keywords: Health · Human endothelial cell · Human hepatocyte · Isomerization · Metabolism · Liarozole · Plasminogen activator · Retinoic acid · Cell culture · Controlled study · Drug metabolism · Endothelium cell · High performance liquid chromatography · Human cell · In vitro study · Isomerism · Isotope labeling · Liver cell culture · Lliver metabolism · Biotransformation · Cells, Cultured · Chromatography, High Pressure Liquid · Endothelium, Vascular · Humans · Isomerism · Kinetics · Liver · Tretinoin · Umbilical Veins
[Abstract]

4 Insulin suppresses bile acid synthesis in cultured rat hepatocytes by down-regulation of cholesterol 7α-hydroxylase and sterol 27-hydroxylase gene transcription
article 1995    
Author: Twisk, J. · Hoekman, M.F.M. · Lehmann, E.M. · Meijer, P. · Mager, W.H. · Princen, H.M.G.
Keywords: Biology · cholesterol 7alpha monooxygenase · insulin · oxygenase · sterol 27 hydroxylase · unclassified drug · animal cell · article · bile acid synthesis · controlled study · down regulation · enzyme activity · gene expression regulation · hormone action · liver cell culture · nonhuman · transcription regulation · Animal · Bile Acids and Salts · Cells, Cultured · Chloramphenicol O-Acetyltransferase · Cholesterol 7-alpha-Hydroxylase · Cytochrome P-450 Enzyme System · Down-Regulation · Gene Expression Regulation, Enzymologic · Insulin · Liver · Male · Membrane Glycoproteins · Nuclear Proteins · Rats · Rats, Wistar · RNA, Messenger · Steroid Hydroxylases · Support, Non-U.S. Gov't · Transcription, Genetic · Transfection
[Abstract]

5 Differential feedback regulation of cholesterol 7α-hydroxylase mRNA and transcriptional activity by rat bile acids in primary monolayer cultures of rat hepatocytes
article 1993    
Author: Twisk, J. · Lehmann, E.M. · Princen, H.M.G.
Keywords: Health · bile acid · chenodeoxycholic acid · cholesterol 7alpha monooxygenase · deoxycholic acid · glycocholic acid · messenger rna · animal cell · bile acid synthesis · controlled study · culture medium · dose time effect relation · down regulation · enzyme activity · enzyme regulation · feedback system · gene expression regulation · gene repression · genetic transcription · hydrophobicity · kinetics · liver cell · liver cell culture · monolayer culture · negative feedback · nonhuman · transcription regulation · Animal · Base Sequence · Bile Acids and Salts · Cells, Cultured · Chenodeoxycholic Acid · Cholesterol 7-alpha-Hydroxylase · Cholic Acid · Cholic Acids · Feedback · Gene Expression Regulation · Glycocholic Acid · Kinetics · Liver · Male · Molecular Sequence Data · Rats · RNA, Messenger · Support, Non-U.S. Gov't · Taurocholic Acid · Transcription, Genetic
[Abstract]

6 Studies on the mechanism of fibrate-inhibited expression of plasminogen activator inhibitor-1 in cultured hepatocytes from cynomolgus monkey
article 1997    
Author: Arts, J. · Kooistra, T.
Keywords: Biology · 9-cis retinoic acid · fibrates · hepatocytes · peroxisome proliferator-activated receptor · plasminogen activator inhibitor-1 · 2 [1 (3 amidinothiopropyl) 1h indol 3 yl] 3 (1 methyl 1h indol 3 yl)maleimide · alitretinoin · antilipemic agent · epidermal growth factor · fibric acid derivative · gemfibrozil · peroxisome proliferator · phorbol 13 acetate 12 myristate · plasminogen activator inhibitor 1 · protein kinase C · protein kinase C inhibitor · retinoid X receptor · transforming growth factor beta · animal cell · controlled study · dose time effect relation · drug mechanism · enzyme activity · gene expression · hyperlipidemia · liver cell culture · monkey · nonhuman · Animals · Antilipemic Agents · Cells, Cultured · Dose-Response Relationship, Drug · Liver · Macaca fascicularis · Plasminogen Activator Inhibitor 1 · RNA, Messenger
[Abstract]

7 Suppression of sterol 27-hydroxylase mRNA and transcriptional activity by bile acids in cultured rat hepatocytes
article 1995    
Author: Twisk, J. · Wit, E.C.M. de · Princen, H.M.G.
Keywords: Biology · bile acid · chenodeoxycholic acid · cholesterol 7alpha monooxygenase · cholic acid · deoxycholic acid · lithocholic acid · messenger rna · oxygenase · sterol · taurocholic acid · animal cell · article · bile acid synthesis · cholesterol metabolism · controlled study · enzyme inhibition · gene repression · liver cell culture · nonhuman · priority journal · rat · transcription regulation · Adenosine Triphosphate · Animal · Bile Acids and Salts · Cells, Cultured · Cholesterol 7-alpha-Hydroxylase · Cytochrome P-450 Enzyme System · Dose-Response Relationship, Drug · Down-Regulation · Gene Expression Regulation, Enzymologic · Liver · Male · Mitochondria · Oxidoreductases · Rats · Rats, Wistar · RNA, Messenger · Steroid Hydroxylases · Support, Non-U.S. Gov't · Taurocholic Acid · Transcription, Genetic
[Abstract]

8 Differential maintenance of cytochrome P450 enzymes in cultured precision-cut human liver slices
article 2000    
Author: Renwick, A.B. · Watts, P.S. · Edwards, R.J. · Barton, P.T. · Guyonnet, I. · Price, R.J. · Tredger, J.M. · Pelkonen, O. · Boobis, A.R. · Lake, B.G.
Keywords: Nutrition · Apoprotein · Cytochrome P450 · Cytochrome p450 2a6 · Cytochrome P450 2B6 · Cytochrome P450 2C19 · Cytochrome p450 2c8 · Cytochrome P450 2C9 · Cytochrome P450 3A4 · Cytochrome P450 3A5 · Debrisoquine 4 hydroxylase · Dimethylnitrosamine demethylase · Ethoxyresorufin · O Deethylase · Peptide antibody · Phenacetin o deethylase · Tolbutamide methylhydroxylase · Unclassified drug · Enzyme activity · Enzyme metabolism · Human tissue · Liver cell culture · Liver slice · Protein stability · School child · Xenobiotic metabolism · Adolescent · Adult · Aged · Child · Child, Preschool · Culture Media · Culture Techniques · Cytochrome P-450 Enzyme System · Enzyme Stability · Female · Humans · Immunoblotting · Isoenzymes · Liver · Male · Microsomes, Liver · Middle Aged
[Abstract]

9 Fiber-chimeric adenoviruses expressing fibers from serotype 16 and 50 improve gene transfer to human pancreatic adenocarcinoma
article 2009    
Author: Kuhlmann, K.F.D. · Geer, M.A. van · Bakker, C.T. · Dekker, J.E.M. · Havenga, M.J.E. · Oude Elferink, R.P.J. · Gouma, D.J. · Bosma, P.J. · Wesseling, J.G.
Keywords: Biology · Biomedical Research · Adenovirus · Fiber-chimeric · Pancreatic cancer · Serotype · adenovirus vector · bacterial enzyme · coxsackie virus and adenovirus receptor · cytosine deaminase · flucytosine · green fluorescent protein · red fluorescent protein · virus DNA · virus fiber protein · Adenovirus fiber gene · Adenovirus fiber knob 5 · Adenovirus type 16 · Adenovirus type 50 · antineoplastic activity · article · bacterial gene · cancer cell culture · cell viability · controlled study · cytosine deaminase gene · drug cytotoxicity · drug efficacy · drug mechanism · drug specificity · fiber chimeric human adenovirus 5 · gene directed enzyme prodrug therapy · gene expression · gene targeting · human · Human adenovirus · Human adenovirus 5 · human cell · human tissue · liver cell culture · molecular cloning · nonhuman · pancreas adenocarcinoma · priority journal · protein domain · protein expression · suicide gene · viral gene delivery system · virus fiber · virus gene · Adenoviridae · Cell Line · Cell Line, Tumor · Flow Cytometry · Gene Therapy · Genetic Vectors · Green Fluorescent Proteins · Humans · Pancreatic Neoplasms · Polymerase Chain Reaction · Recombinant Fusion Proteins · Recombination, Genetic · Transduction, Genetic · Viral Envelope Proteins · Adenoviridae
[Abstract]

10 17α-Ethyl-5β-estrane-3α,17β-diol, a biological marker for the abuse of norethandrolone and ethylestrenol in slaughter cattle
article 1999    
Author: Puymbroeck, M. van · Kuilman, M.E.M. · Maas, R.F.M. · Witkamp, R.F. · Leyssens, L. · Miert, A.S.J.P.A.M. van · Hendriks, L. · Zande, D.J.M. van der · Adriaensens, P. · Jacobs, M.-P. · Raus, J.
Keywords: Nutrition · 17α-Ethyl-5β-estrane-3α,17β-diol · Ethylestrenol · Norethandrolone · Steroids · Biological marker · Ethylestrenol · Norethandrolone · 17Alpha ethyl 5 xi estrane 3 xi,17 beta diol · Drug derivative · Drug residue · Estradiol · Animal experiment · Animal tissue · Article · Biotransformation · Cattle · Drug abuse · Drug metabolism · Drug monitoring · Feces · Female · Intramuscular drug administration · Liver · Liver cell culture · Male · Nonhuman · Priority journal · Reduction · Urine · Animal · Animal husbandry · Chemistry · High performance liquid chromatography · Liver microsome · Mass fragmentography · Nuclear magnetic resonance spectroscopy · Sensitivity and specificity · Standard · Thin layer chromatography · Ultraviolet spectrophotometry · Biological Markers · Cattle · Chromatography, High Pressure Liquid · Chromatography, Thin Layer · Drug Residues · Estradiol · Ethylestrenol · Gas Chromatography-Mass Spectrometry · Magnetic Resonance Spectroscopy · Male · Microsomes, Liver · Norethandrolone · Reference Standards · Sensitivity and Specificity · Spectrophotometry, Ultraviolet
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 10 of 10 found. | Sort by date