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Showing 1 to 20 of 120 found. Next | Sort by date

1 The hepatic uptake of VLDL in lrp-ldlr-/-vldlr-/- mice is regulated by LPL activity and involves proteoglycans and SR-BI
article 2008    
Author: Hu, L. · Hoogt, C.C. van der · Espirito Santo, S.M.S. · Out, R. · Kypreos, K.E. · Vlijmen, B.J.M. van · Berkel, T.J.C. van · Romijn, J.A. · Havekes, L.M. · Dijk, K.W. van · Rensen, P.C.N.
Keywords: Biology · Apolipoprotein · Denovirus-mediated gene transfer · Lipoprotein lipase · Low density lipoprotein receptor · Low density lipoprotein receptor-related protein · Transgenic mice · Triglyceride-rich emulsion particles · Very low density lipoprotein receptor · apolipoprotein E · cell surface protein · cholesterol · lipoprotein lipase · low density lipoprotein receptor · low density lipoprotein receptor related protein · proteoglycan · proteoheparan sulfate · scavenger receptor BI · triacylglycerol · very low density lipoprotein · very low density lipoprotein receptor · CD36 antigen · ligand · very low density lipoprotein cholesterol · Adenovirus · animal cell · animal experiment · animal tissue · article · cell isolation · cell surface · controlled study · enzyme activity · in vitro study · in vivo study · internalization · lipid analysis · liver cell · male · mouse · nonhuman · priority journal · protein expression · regulatory mechanism · animal · blood · emulsion · genetics · liver · metabolism · mouse mutant · Animals · Antigens, CD36 · Cholesterol, VLDL · Emulsions · LDL-Receptor Related Proteins · Ligands · Lipoprotein Lipase · Liver · Male · Mice · Mice, Knockout · Proteoglycans · Receptors, LDL · Healthy for Life · Healthy Living
[Abstract]

2 Predicting individual responses to pravastatin using a physiologically based kinetic model for plasma cholesterol concentrations
article 2014    
Author: Pas, N.C.A. van de · Rullmann, J.A.C. · Woutersen, R.A. · Ommen, B. van · Rietjens, I.M.C.M. · Graaf, A.A. de
Keywords: Biology · Cholesterol · LDL · PBK modeling · Personalized medicine · Statin response · Virtual subjects · cholesterol · High density lipoprotein cholesterol · Low density lipoprotein cholesterol · Low density lipoprotein receptor · Pravastatin · Very low density lipoprotein cholesterol · Cholesterol blood level · Cholesterol synthesis · Drug effect · Drug mechanism · Human · Kinetics · Major clinical study · Monte Carlo method · Physiologically based kinetic · Protein expression · Biomedical Innovation · Healthy Living · Life · MSB - Microbiology and Systems Biology · ELSS - Earth, Life and Social Sciences
[Abstract]

3 Clearance of coagulation factor VIII in very low-density lipoprotein receptor knockout mice
article 2004    
Author: Bovenschen, N. · Dijk, K.W. van · Havekes, L.M. · Mertens, K. · Vlijmen, B.J.M. van
Keywords: Biology · Biomedical Research · Clearance · Factor VIII · Knockout mice · Low-density lipoprotein receptor-related protein · Very low-density lipoprotein receptor · blood clotting factor 8 · cholesterol · triacylglycerol · very low density lipoprotein receptor · animal experiment · article · catabolism · cholesterol blood level · controlled study · knockout mouse · male · mouse · nonhuman · plasma clearance · priority journal · triacylglycerol blood level · Animals · Factor VIII · Integrases · LDL-Receptor Related Proteins · Mice · Mice, Knockout · Mice, Transgenic · Receptors, LDL
[Abstract]

4 Potential of 99mTc-LDLs labeled by two different methods for scintigraphic detection of experimental atherosclerosis in rabbits
article 1993    
Author: Atsma, D.E. · Feitsma, R.I.J. · Camps, J. · Hooft, F.M. van 't · Wall, E.E. van der · Nieuwenhuizen, W. · Pauwels, E.K.J.
Keywords: Biology · LDL · Rradiolabeling · Scintigraphy · Dithionite · Low density lipoprotein · Sodium borohydride · Stannous chloride · Technetium 99m · Borane derivative · Borohydride potassium · Diagnostic agent · Technetium complex · Technetium Tc 99m low density lipoprotein · Technetium Tc 99m low-density lipoprotein · Abdominal aorta · Animal experiment · Animal model · Animal tissue · Clearance · Controlled study · Intermethod comparison · Isotope labeling · Scintiscanning · Thoracic aorta · Animal · Aorta · Arteriosclerosis · Borohydrides · Dithionite · Lipoproteins, LDL · Male · Organotechnetium Compounds · Rabbits · Support, Non-U.S. Gov't · Tin
[Abstract]

5 Hepatocyte-specifi c IKK- β activation enhances VLDL-triglyceride production in APOE*3-Leiden mice
article 2011    
Author: Diepen, J.A.V. · Wong, M.C. · Guigas, B. · Bos, J. · Stienstra, R. · Hodson, L. · Shoelson, S.E. · Jimmy F. P. Berbée · Rensen, P.C.N. · Romijn, J.A. · Havekes, L.M. · Voshol, P.J.
Keywords: Health · I k B kinase β · Lipid metabolism · Liver · Nuclear factor kappa B · Very low density lipoprotein · Life · MHR - Metabolic Health Research · EELS - Earth, Environmental and Life Sciences
[PDF] [Abstract]

6 CETP expression reverses the reconstituted HDL-induced increase in VLDL
article 2011    
Author: Wang, Y. · Berbée, J.F.P. · Stroes, E.S. · Smit, J.W.A. · Havekes, L.M. · Romijn, J.A. · Rensen, P.C.N.
Keywords: Health · Cholesterol · Cholesteryl ester transfer protein · High density lipoprotein · Transgenic mice · Triglycerides · Very low density lipoprotein production · Life · MHR - Metabolic Health Research · EELS - Earth, Environmental and Life Sciences
[PDF] [Abstract]

7 Effect of methylglyoxal on the physico-chemical and biological properties of low-density lipoprotein
article 1998    
Author: Schalkwijk, C.G. · Vermeer, M.A. · Stehouwer, C.D.A. · Koppele, J. te · Princen, H.M.G. · Hinsbergh, V.W.M. van
Keywords: Biology · Advanced glycation end product · Diabetes · Low density lipoprotein · Methylglyoxal · Arginine · Cholesterol ester · Cytochrome c · Iodine 125 · Low density lipoprotein · Low density lipoprotein receptor · Lysine · Methylglyoxal · Monocyte chemotactic protein 1 · Oxidized low density lipoprotein · Superoxide · Vasculotropin · Controlled study · Fluorescence · Human · Human cell · Isotope labeling · Lipid metabolism · Macrophage · Plasma clearance · Priority journal · Receptor affinity · Animals · Cell Line · Chemistry, Physical · Cytochrome c Group · Electrochemistry · Endothelium, Vascular · Fibroblasts · Humans · Lipid Peroxidation · Lipid Peroxides · Lipoproteins, LDL · Macrophages · Malondialdehyde · Mice · Oxidation-Reduction · Pyruvaldehyde · Receptors, LDL · Superoxides · Thiobarbituric Acid Reactive Substances · Murinae
[Abstract]

8 Low-density lipoproteins are degraded in HepG2 cells with low efficiency
article 1993    
Author: Lombardi, P. · Mulder, M. · Wit, E. de · Berkel, T.J.C. van · Frants, R.R. · Havekes, L.M.
Keywords: Low density lipoprotein · Low density lipoprotein receptor · Cell density · Cell fractionation · Comparative study · Density gradient centrifugation · Endosome · Hepatoma cell · Human cell · Internalization · Isotope labeling · Lipoprotein metabolism · Protein degradation · Receptor down regulation · Biological Transport · Cell Aggregation · Cell Line · Cells, Cultured · Down-Regulation · Fibroblasts · Human · Iodine Radioisotopes · Kinetics · Lipoproteins, LDL · Liver · Lysosomes · Receptors, LDL · Support, Non-U.S. Gov't
[Abstract]

9 Inefficient degradation of triglyceride-rich lipoprotein by HepG2 cells is due to a retarded transport to the lysosomal compartment
article 1993    
Author: Lombardi, P. · Mulder, M. · Boom, H. van der · Frants, R.R. · Havekes, L.M.
Keywords: Cholesterol acyltransferase · Lipoprotein · Lipoprotein receptor · Low density lipoprotein · Triacylglycerol · Very low density lipoprotein · Cholesterol blood level · Density gradient centrifugation · Endosome · Enzyme activity · Homeostasis · Human cell · Lipid transport · Protein binding · Protein degradation · Biological Transport · Cell Compartmentation · Cell Line · Cholesterol · Endocytosis · Esterification · Human · Lipoprotein Lipase · Lipoproteins, LDL · Lipoproteins, VLDL · Lysosomes · Sterol O-Acyltransferase · Support, Non-U.S. Gov't · Triglycerides
[PDF] [Abstract]

10 Apolipoprotein AV: Low concentration, high impact
article 2005    
Author: Rensen, P.C.N. · Dijk, K.W. van · Havekes, L.M.
Keywords: Biomedical Research · Apolipoprotein A5 · High density lipoprotein · Lipoprotein lipase · Low density lipoprotein receptor · Triacylglycerol · Very low density lipoprotein · APOA5 protein, human · Editorial · Enzyme linked immunosorbent assay · Homeostasis · Ischemic heart disease · Lipid metabolism · Nonhuman · Protein assembly · Triacylglycerol blood level · Animal · Blood · Metabolism · Note · Physiology · Animals · Apolipoproteins · Apolipoproteins A · Homeostasis · Humans · Hypertriglyceridemia · Triglycerides
[Abstract]

11 Triglyceride-rich lipoprotein metabolism in unique VLDL receptor, LDL receptor, and LRP triple-deficient mice
article 2005    
Author: Espirito Santo, S.M.S. · Rensen, P.C.N. · Goudriaan, J.R. · Bensadoun, A. · Bovenschen, N. · Voshol, P.J. · Havekes, L.M. · Vlijmen, B.J.M. van
Keywords: Biology · Biomedical Research · Apolipoprotein E · Hepatic lipase · Hyperlipidemia · Lipoprotein lipase · Low density lipoprotein receptor · Postprandial response · Transgenic mice · Very low density lipoprotein receptor · Very low density lipoproteins · Lipid · Low density lipoprotein receptor · Low density lipoprotein receptor related protein · Triacylglycerol lipase · Very low density lipoprotein receptor · Leucine responsive regulatory protein · Lipoprotein · Transcription factor · Animal experiment · Animal model · Animal tissue · Controlled study · Female · gene deletion · Hyperlipidemia · Lipid blood level · Lipid diet · Male · Mouse · Nonhuman · Protein defect · Species comparison · Triacylglycerol blood level · Triacylglycerol lipase blood level · Wild type · Chemistry · Genetics · Metabolism · Pathology · Physiology · Polymerase chain reaction · Time · Transgenic mouse · Alleles · Animals · Cholesterol · DNA-Binding Proteins · Genotype · Hyperlipidemias · Leucine-Responsive Regulatory Protein · Lipid Metabolism · Lipoproteins · Mice · Mice, Transgenic · Polymerase Chain Reaction · Receptors, LDL · Time Factors · Transcription Factors · Triglycerides
[PDF] [Abstract]

12 LDL receptor deficiency results in decreased cell proliferation and presynaptic bouton density in the murine hippocampus
article 2007    
Author: Mulder, M. · Koopmans, G. · Wassink, G. · Mansouri, G.A. · Simard, M.-L. · Havekes, L.M. · Prickaerts, J. · Blokland, A.
Keywords: Health · Biomedical Research · Apolipoprotein E · Cholesterol · Low density lipoprotein receptor · Memory · Neurogenesis · Synaptic density · apolipoprotein E · broxuridine · cholesterol · iodine 125 · low density lipoprotein · low density lipoprotein receptor · synaptophysin · Alzheimer disease · animal cell · animal experiment · animal tissue · article · astrocytoma cell · cell proliferation · cholesterol metabolism · concentration response · controlled study · dentate gyrus · hippocampus · knockout mouse · male · memory · mouse · nerve cell plasticity · nerve fiber growth · nervous system development · neuroblastoma cell · nonhuman · pathogenesis · priority journal · spatial memory · synaptogenesis · wild type · Animals · Biological Markers · Bromodeoxyuridine · Cell Count · Cell Line, Tumor · Cell Proliferation · Cholesterol · Dentate Gyrus · Down-Regulation · Hippocampus · Humans · Male · Mice · Mice, Knockout · Neural Pathways · Neuronal Plasticity · Presynaptic Terminals · Receptors, LDL · Synaptophysin
[Abstract]

13 Scavenger Receptor BI Plays a Role in Facilitating Chylomicron Metabolism
article 2004    
Author: Out, R. · Kruijt, J.K. · Rensen, P.C.N. · Hildebrand, R.B. · Vos, P. de · Eck, M. van · Berkel, T.J.C. van
Keywords: Biology · Biomedical Research · Emulsions · Metabolism · Proteins · Cell association · High density lipoproteins (HDL) · Biochemistry · Chylomicron · High density lipoprotein cholesterol · Low density lipoprotein receptor · Low density lipoprotein receptor related protein · Oxidized low density lipoprotein · Scavenger receptor · Scavenger receptor BI · Triacylglycerol · Unclassified drug · Animal cell · Animal experiment · Cholesterol transport · Controlled study · Emulsion · Internalization · Lipid metabolism · Liver cell · Molecular recognition · Mouse · Nonhuman · Postprandial state · Animals · Antigens, CD36 · Binding Sites · Biological Transport · Chylomicron Remnants · Chylomicrons · Emulsions · Hepatocytes · Mice · Mice, Mutant Strains · Receptors, Immunologic · Receptors, Scavenger · Scavenger Receptors, Class B · Tissue Distribution · Triglycerides · Animalia
[PDF] [Abstract]

14 The VLDL receptor plays a major role in chylomicron metabolism by enhancing LPL-mediated triglyceride hydrolysis
article 2004    
Author: Goudriaan, J.R. · Espirito Santo, S.M.S. · Voshol, P.J. · Teusink, B. · Dijk, K.W. van · Vlijmen, B.J.M. van · Romijn, J.A. · Havekes, L.M. · Rensen, P.C.N.
Keywords: Biology · Biomedical Research · Adipose tissue · Free fatty acids · Lipoprotein lipase · Postprandial lipid metabolism · Transgenic mice · Very low density lipoprotein-like emulsion · Albumin · Carbon 14 · Chylomicron · Fatty acid · Lipoprotein lipase · Triacylglycerol · Very low density lipoprotein · Very low density lipoprotein receptor · Animal experiment · Animal tissue · Bolus injection · Continuous infusion · Controlled study · Diet restriction · Emulsion · Enzyme activity · Fatty acid transport · Female · Half life time · Lipid blood level · Lipid hydrolysis · Lipid metabolism · Lipolysis · Mouse · Nonhuman · Plasma clearance · Postprandial state · Protein expression · Transgenic mouse · Adipose Tissue · Albumins · Animals · Chylomicrons · Fatty Acids, Nonesterified · Mice · Receptors, LDL · Triglycerides
[PDF] [Abstract]

15 PCSK9 inhibition fails to alter hepatic LDLR, circulating cholesterol, and atherosclerosis in the absence of ApoE
article 2014    
Author: Ason, B. · Hoorn, J.W.A. van der · Chan, J. · Lee, E. · Pieterman, E.J. · Nguyen, K.K. · Di, M. · Shetterly, S. · Tang, J. · Yeh, W.C. · Schwarz, M. · Jukema, J.W. · Scott, R. · Wasserman, S.M. · Princen, H.M.G. · Jackson, S.
Keywords: Biology · Anti-proprotein convertase subtilisin/kexin type 9 antibody · Apolipoprotein E · Low density lipoprotein receptor · Proprotein convertase subtilisin/kexin type 9 · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · ELSS - Earth, Life and Social Sciences
[PDF] [Abstract]

16 Effect of homocysteine-lowering nutrients on blood lipids: Results from four randomised, placebo-controlled studies in healthy humans
article 2005    
Author: Olthof, M.R. · Vliet, T. van · Verhoef, P. · Zock, P.L. · Katan, M.B.
Keywords: Biology · Biomedical Research · betaine · folic acid · high density lipoprotein cholesterol · homocysteine · lipid · low density lipoprotein cholesterol · phosphatidylcholine · placebo · protein inhibitor · triacylglycerol · adult · calculation · confidence interval · controlled study · diet supplementation · female · lipid blood level · male · time series analysis · vitamin supplementation
[PDF] [Abstract]

17 Insulin suppresses apolipoprotein(a) synthesis in cultured cynomolgus monkey hepatocytes
article 1999    
Author: Princen, H.M.G.
Keywords: Biology · Apolipoprotein a · Apolipoprotein b · Cholesterol · Insulin · Lipoprotein a · Very low density lipoprotein · Animal cell · Drug half life · Hepatoma cell · Human · Hyperinsulinemia · Insulin dependent diabetes mellitus · Letter · Lipoprotein synthesis · Liver cell · Monkey · Nonhuman

18 Binding of LP(a) to the low density lipoprotein receptor of human fibroblasts
article 1981    
Author: Havekes, L. · Vermeer, B.J. · Brugman, T. · Emeis, J.
Keywords: low density lipoprotein · fibroblast culture · human cell · in vitro study · Cells, Cultured · Fibroblasts · Fluorescent Antibody Technique · Human · Hypercholesterolemia, Familial · Lipoprotein(a) · Lipoproteins · Lipoproteins, LDL · Male · Microscopy, Electron · Middle Age · Receptors, Cell Surface · Receptors, LDL
[PDF] [Abstract]

19 Aspirin reduces hypertriglyceridemia by lowering VLDL-triglyceride production in mice fed a high-fat diet
article 2011    
Author: Diepen, J.A. van · Vroegrijk, I.O.C.M. · Berbée, J.F.P. · Shoelson, S.E. · Romijn, J.A. · Havekes, L.M. · Rensen, P.C.N. · Voshol, P.J.
Keywords: Biology · Inflammation · Lipid metabolism · Very low-density lipoprotein · acetylsalicylic acid · apolipoprotein C1 · immunoglobulin enhancer binding protein · transcription factor RelA · triacylglycerol · very low density lipoprotein cholesterol · animal experiment · animal model · article · cholesterol blood level · controlled study · drug mechanism · drug targeting · enzyme inhibition · gene expression · hypertriglyceridemia · in vivo study · lipid diet · lipogenesis · lipoprotein blood level · male · metabolic syndrome X · mouse · nonhuman · priority journal · protein expression · risk factor · triacylglycerol blood level · aspirin · Healthy Living · Life · MHR - Metabolic Health Research · EELS - Earth, Environmental and Life Sciences
[Abstract]

20 Enhanced susceptibility of low-density lipoproteins to oxidation in coronary bypass patients with progression of atherosclerosis
article 1995    
Author: Rijke, Y.B. de · Verwey, H.F. · Vogelezang, C.J.M. · Velde, E.A. van der · Princen, H.M.G. · Laarse, A. van der · Bruschke, A.V.G. · Berkel, T.J.C. van
Keywords: Biology · apolipoprotein B · coronary artery bypass surgery · coronary atherosclerosis · lipid peroxidation · low-density lipoprotein · apolipoprotein a · apolipoprotein b · cholesterol · high density lipoprotein · low density lipoprotein · retinol · triacylglycerol · adult · aged · angiography · article · atherosclerosis · blood analysis · clinical article · controlled study · coronary artery bypass graft · human · human tissue · lipid analysis · lipid oxidation · male · priority journal · Apolipoproteins · Arteriosclerosis · Ascorbic Acid · Centrifugation, Density Gradient · Coronary Artery Bypass · Disease Progression · Follow-Up Studies · Humans · Lipoproteins, LDL · Male · Middle Aged · Oxidation-Reduction · Triglycerides · Vitamin E
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 120 found. Next | Sort by date