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Showing 1 to 9 of 9 found. | Sort by date

1 Modification of the early and late delayed radiation response of the rat spinal cord by chemotherapeutic agents
article 1981    
Author: Kogel, A.J. van der
Keywords: cytarabine · methotrexate · abstract report · animal experiment · central nervous system · intramuscular drug administration · intrathecal drug administration · intravenous drug administration · radiation injury · rat · spinal cord
[Abstract]

2 Transport of glutathione A conjugates by the multifrug resistance protein 1
article 1997    
Author: Evers, R. · Cnubben, N.H.P. · Wijnholds, J. · Deemter, L. van · Bladeren, P.J. van · Borst, P.
Keywords: GS-X pump · Multidrug resistance · Adenosine Triphosphate · Animals · Biological Transport · Cell Line · Cell Polarity · Cyclic AMP · Dogs · Erythrocytes · Ethacrynic Acid · Glutathione · Humans · Kidney · Methotrexate · Mice · Mice, Mutant Strains · Microsomes · P-Glycoprotein · Prostaglandins A, Synthetic · Stereoisomerism
[PDF] [Abstract]

3 Leflunomide and methotrexate reduce levels of activated matrix metalloproteinases in complexes with α2 macroglobulin in serum of rheumatoid arthritis patients
article 2008    
Author: Tchetverikov, I. · Kraan, M.C. · El, B. van · Hanemaaijer, R. · Groot, J. de · Huizinga, T.W.J.
Keywords: Biology · Biomedical Research · alpha 2 macroglobulin · C reactive protein · leflunomide · matrix metalloproteinase · methotrexate · teriflunomide · tissue inhibitor of metalloproteinase 1 · analysis · blood sampling · clinical study · complex formation · controlled study · disease activity · drug activity · drug dose increase · drug effect · drug efficacy · drug exposure · loading drug dose · major clinical study · priority journal · protein blood level · quantitative analysis · rheumatoid arthritis · serum · systemic circulation · Aged · alpha-Macroglobulins · Antirheumatic Agents · Arthritis, Rheumatoid · Biological Markers · C-Reactive Protein · Down-Regulation · Enzyme Inhibitors · Female · Humans · Isoxazoles · Male · Matrix Metalloproteinases · Methotrexate · Middle Aged · Multiprotein Complexes · Phenylalanine · Statistics, Nonparametric · Thiophenes
[Abstract]

4 Bone turnover, joint damage and bone mineral density in early rheumatoid arthritis treated with combination therapy including high-dose prednisolone
article 2001    
Author: Verhoeven, A.C. · Boers, M. · Koppele, J.M. te · Laan, W.H. van der · Markusse, H.M.Geusens, P. · Linden, S. van der
Keywords: Health Biology · Biomedical Research · Adult · Aged · Amino Acids · Anti-Inflammatory Agents · Anti-Inflammatory Agents, Non-Steroidal · Antirheumatic Agents · Arthritis, Rheumatoid · Bone Density · Bone Remodeling · Collagen · Cross-Linking Reagents · Drug Therapy, Combination · Female · Humans · Joints · Male · Methotrexate · Middle Aged · Postmenopause · Prednisolone · Regression Analysis · Sulfasalazine · Bone mineral density · Collagen crosslinks · Deoxypyridinoline · Early rheumatoid arthritis · Glucocorticoids · Outcomes · Pyridinoline
[Abstract]

5 The antiinflammatory drug sulfasalazine inhibits tumor necrosis factor alpha expression in macrophages by inducing apoptosis
article 2000    
Author: Rodenburg, R.J.T. · Ganga, A. · Lent, P.L.E.M. van · Putte, L.B.A. van de · Venrooij, W.J. van
Keywords: Nutrition · Medicine · Geneeskunde · Pharmacology · Toxicology · Caspase 8 · Salazosulfapyridine · Tumor necrosis factor alpha · Animal cell · Antiinflammatory activity · Apoptosis · Crohn disease · Cytokine production · Drug mechanism · Macrophage · Mouse · Nonhuman · Priority journal · Protein expression · Rheumatoid arthritis · Adenosine · Animals · Anti-Inflammatory Agents, Non-Steroidal · Apoptosis · Caspases · Cells, Cultured · Cysteine Proteinase Inhibitors · Humans · Macrophage Activation · Macrophages · Macrophages, Peritoneal · Methotrexate · Mice · Mice, Inbred C57BL · Sulfasalazine · Tumor Necrosis Fac
[Abstract]

6 Intra arterial infusion with methotrexate in the rat
article 1974    
Author: Sindram, P.J. · Snow, G.B. · Putten, L.M. van
Keywords: folinate calcium · folinic acid · cancer · cancer chemotherapy · cancer graft · chemotherapy · drug dose · drug mixture · head and neck cancer · intraarterial drug administration · intraperitoneal drug administration · theoretical study · Animal · Catheterization · Comparative Study · Ear Neoplasms · Injections, Intra-Arterial · Injections, Intraperitoneal · Leucovorin · Male · Methotrexate · Models, Biological · Neoplasms, Experimental · Rats · Rhabdomyosarcoma
[PDF] [Abstract]

7 Ontwikkelingen in de diagnostiek en behandeling van leukemie bij kinderen met downsyndroom = Developments in diagnosis and treatment of leukemia in children with Down syndrome
article 2009    
Author: Blink, M. · Buitenkamp, T.D. · Wouwe, J.P. van · Wering, E.R. van · Velden, V.H.J. van der · Zwaan, C.M.
Keywords: Health · Cytostatic agent · Methotrexate · Acute granulocytic leukemia · Acute lymphoblastic leukemia · Acute lymphocytic leukemia · Cancer patient · Cancer survival · Clinical feature · Clinical protocol · Disease severity · Down syndrome · High risk patient · Human · Leukemia · Lymphoblast · Mucosa inflammation · Netherlands · Prognosis · Symptomatology · Treatment outcome · Unspecified side effect
[Abstract]

8 Prediction of in vivo embryotoxic effect levels with a combination of in vitro studies and PBPK modelling
article 2006    
Author: Verwei, M. · Burgsteden, J.A. van · Krul, C.A.M. · Sandt, J.J.M. van de · Freidig, A.P.
Keywords: Biology · Biomedical Research · Alternative test method · Developmental toxicity · Embryonic stem cells · PBPK model · 2 ethoxyethanol · 2 methoxyethanol · acetic acid derivative · ethoxyacetic acid · fluorouracil · methotrexate · methoxyacetic acid · retinoic acid · unclassified drug · animal cell · article · computer model · controlled study · embryo · embryo development · embryonic stem cell · embryotoxicity · exposure · metabolism · mouse · nonhuman · prediction · priority journal · risk assessment · rodent · Animal Testing Alternatives · Animals · Cell Line · Cell Survival · Dose-Response Relationship, Drug · Embryo · Mice · Models, Biological · Predictive Value of Tests · Rats · Risk Assessment · Stem Cells · Teratogens · Toxicity Tests · Rodentia
[Abstract]

9 Erosive arthritis in a patient with pycnodysostosis: An experiment of nature
article 2008    
Author: Ainola, M. · Valleala, H. · Nykänen, P. · Risteli, J. · Hanemaaijer, R. · Konttinen, Y.T.
Keywords: Health · acid phosphatase tartrate resistant isoenzyme · calcitonin receptor · carboxy terminal telopeptide · cathepsin K · folic acid · hydroxychloroquine · ketoprofen · matrix metalloproteinase · messenger RNA · methotrexate · n [n (3 carboxyoxirane 2 carbonyl)leucyl]agmatine · prednisolone · salazosulfapyridine · adult · article · bone defect · bone erosion · case report · collagen degradation · controlled study · drug withdrawal · dysostosis · female · hand radiography · human · human cell · monocyte · multinuclear cell · nucleotide sequence · osteoclast · osteolysis · priority journal · psoriatic arthritis · pyknodysostosis · rash · synovitis · Acid Phosphatase · Arthritis, Psoriatic · Bone Resorption · Cathepsins · Cells, Cultured · Dysostoses · Female · Humans · Middle Aged · Monocytes · Osteoclasts · Receptors, Calcitonin
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 9 of 9 found. | Sort by date