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Showing 1 to 16 of 16 found. | Sort by date

1 Safety evaluation of pectin-derived acidic oligosaccharides (pAOS): genotoxicity and sub-chronic studies
article 2010    
Author: Garthoff, J.A. · Heemskerk, S. · Hempenius, R.A. · Lina, B.A.R. · Krul, C.A.M. · Koeman, J.H. · Speijers, G.J.A.
Keywords: Ames · Chromosomal aberration · In utero · Infant formulae · Medical foods · Micronucleus · Mouse lymphoma · Non-digestible carbohydrates · PAOS
[Abstract]

2 SFTG international collaborative study on in vitro micronucleus test. II. Using human lymphocytes
article 2006    
Author: Clare, M.G. · Lorenzon, G. · Akhurst, L.C. · Marzin, D. · Delft, J. van · Montero, R. · Botta, A. · Bertens, A. · Cinelli, S. · Thybaud, V. · Lorge, E.
Keywords: Toxicology · Toxicology and Applied Pharmacology · Aneugen · Clastogen · Cytochalasin B · Human lymphocytes · In vitro micronucleus assay · aneugen · bleomycin · clofibrate · colchicine · cytarabine · cytochalasin B · diethylstilbestrol · fluorouracil · mannitol · mitomycin C · tiabendazole · urethan · adult · article · cell culture · cell cycle · cell division · cell nucleus · chemical analysis · controlled study · data analysis · female · human · human cell · lymphocyte · male · micronucleus test · mitogenicity · mononuclear cell · priority journal · reproducibility · sensitivity analysis · Adult · Aneugens · Bleomycin · Clofibrate · Colchicine · Cytarabine · Diethylstilbestrol · Female · Fluorouracil · Humans · International Cooperation · Lymphocytes · Male · Mannitol · Micronucleus Tests · Mutagens · Thiabendazole · Urethane
[Abstract]

3 The in vivo rat skin photomicronucleus assay: Phototoxicity and photogenotoxicity evaluation of six fluoroquinolones
article 2012    
Author: Reus, A.A. · Usta, M. · Kenny, J.D. · Clements, P.J. · Pruimboom-Brees, I. · Aylott, M. · Lynch, A.M. · Krul, C.A.M.
Keywords: Research · ciprofloxacin · gatifloxacin · gemifloxacin · levofloxacin · lomefloxacin · methoxsalen · quinoline derived antiinfective agent · sparfloxacin · animal tissue · article · carcinogenicity · controlled study · epidermis cell · female · genotoxicity · hairless mouse · histopathology · in vitro study · in vivo study · micronucleus · micronucleus test · nonhuman · phototoxicity · priority journal · rat · single drug dose · skin · Sprague Dawley rat · Biomedical Innovation · Healthy Living · Triskelion BV · TARA - Toxicology and Risk Assessment · TNO Bedrijven
[Abstract]

4 Evaluation of the in vivo genetic toxicity of concentrated barley β-glucan
article 2004    
Author: Delaney, B. · Vogel, N. de · Krul, C.A.M.
Keywords: Health Biology · Physiological Sciences · beta glucan · corn oil · mitomycin C · analysis of variance · barley · bone marrow cell · cereal · erythrocyte · evaluation · femur · genetic toxicology · grain · hypercholesterolemia · letter · micronucleus · nonhuman · Animals · Diet · Erythrocytes · Glucans · Hordeum · Male · Mice · Micronucleus Tests · Mutagenicity Tests · Mutagens · Hordeum vulgare subsp. vulgare · Zea mays
[Abstract]

5 Beta-carotene supplementation in smokers reduces the frequency of nnicronuclei in sputum
article 1992    
Author: Poppel, G. van · Kok, F.J. · Hermus, R.J.J.
Keywords: alpha tocopherol · ascorbic acid · cotinine · cigarette smoking · clinical trial · controlled study · diet supplementation · dna damage · double blind procedure · human cell · human experiment · lung carcinogenesis · micronucleus · normal human · oral drug administration · vitamin blood level · Adult · beta Carotene · Carotenoids · DNA Damage · Double-Blind Method · Human · Male · Micronucleus Tests · Middle Age · Skin Pigmentation · Smoking · Sputum
[PDF] [Abstract]

6 IPCS guidelines for the monitoring of genotoxic effects of carcinogens in humans
article 2000    
Author: Albertini, R.J. · Anderson, D. · Douglas, G.R. · Hagmar, L. · Hemminki, K. · Merlo, F. · Natarajan, A.T. · Norppa, H. · Shuker, D.E.G. · Tice, R. · Waters, M.D. · Aitio, A.
Keywords: Biomarkers · Biomonitoring · Genotoxic carcinogens · Guideline · Human populations · WHO · carcinogen · hypoxanthine phosphoribosyltransferase · blood analysis · carcinogenicity · chromosome aberration · comet assay · cytogenetics · DNA adduct · DNA damage · ethics · fluorescence in situ hybridization · gene mutation · genotoxicity · human · micronucleus test · patient monitoring · practice guideline · priority journal · protein binding · review · risk assessment · sampling · sister chromatid exchange · statistical analysis · technique · Carcinogens · Chromosome Aberrations · DNA Damage · Environmental Health · Environmental Monitoring · Humans · Hypoxanthine Phosphoribosyltransferase · In Situ Hybridization, Fluorescence · International Cooperation · Lymphocytes · Micronucleus Tests · Mutagens · Sister Chromatid Exchange · Toxicity Tests · United Nations · World Health Organization
[Abstract]

7 Genotoxicity and mutagenicity
article 2005    
Author: Maurici, D. · Aardema, M. · Corvi, R. · Kleber, M. · Krul, C.A.M. · Laurent, C. · Loprieno, N. · Pasanen, M. · Pfuhler, S. · Phillips, B. · Sabbioni, E. · Sanner, T. · Vanparys, P.
Keywords: Toxicology · Physiological sciences · Animal testing replacement · Animal testing alternatives · Chromosome aberration · Comet assay · DNA damage · DNA synthesis · Gene mutation · Genotoxicity · In vitro study · In vivo study · Micronucleus test · Mitotic recombination · Mutagenicity · Sister chromatid exchange · Toxicity testing · Toxicogenetics · Toxicokinetics · Toxicological parameters · Carcinogen testing · Cell culture · Chemistry · Legal aspects · Structure activity relation · Animalia · Consumer product safety · Cosmetics · European Union · Structure-Activity Relationship

8 Human diets cooked by microwave or conventionally : comparative sub-chronic (13-wk) toxicity study in rats
article 1995    
Author: Jonker, D. · Til, H.P.
Keywords: Toxicology · Analysis of Variance · Animal · Bladder · Blood Cells · Blood Chemical Analysis · Bone Marrow Cells · Comparative Study · Drinking · Eating · Erythrocytes · Female · Food · Food Handling · Freeze Drying · Human · Male · Micronucleus Tests · Microwaves · Organ Weight · Random Allocation · Rats · Rats, Wistar · Specific Pathogen-Free Organisms · Support, Non-U.S. Gov't · Urinalysis · Animalia · Rattus norvegicus · Rodentia · Solanum tuberosum
[Abstract]

9 Effect of short-term dietary administration of eugenol in humans
article 1996    
Author: Rompelberg, C.J.M. · Vogels, J.T.W.E. · Vogel, N. de · Bruijntjes-Rozier, G.C.D.M. · Stenhuis, W.H. · Bogaards, J.J.P. · Verhagen, H.
Keywords: Nutrition · Antigenotoxicity · Eugenol · GST · antitoxin · eugenol · glutathione transferase · mitomycin c · vinblastine · article · biotransformation · blood sampling · chromosome aberration · controlled study · enzyme activity · erythrocyte · genotoxicity · human · human experiment · leukocyte · male · micronucleus · priority journal · xenobiotic metabolism · Acetaminophen · Adult · Antibiotics, Antineoplastic · Antineoplastic Agents, Phytogenic · Biotransformation · Cells, Cultured · Chromosome Aberrations · Cross-Over Studies · Erythrocytes · Eugenol · Glutathione Transferase · Humans · Intervention Studies · Leukocytes · Liver · Magnetic Resonance Spectroscopy · Male · Mitomycin · Vinblastine
[Abstract]

10 Absence of an effect of lead acetate on sperm morphology, sister chromatid exchanges or on micronuclei formation in rabbits
article 1982    
Author: Willems, M.I. · Schepper, G.G.de · Wibowo, A.A.E. · Immel, H.R. · Dietrich, A.J.J. · Zielhuis, R.L.
Keywords: Broxuridine · Cadmium · Lead acetate · Zinc · Animal experiment · Blood and hemopoietic system · Bone marrow · Erythrocyte · Histology · Lymphatic system · Lymphocyte · Male genital system · Micronucleus · Microscopy · Rabbit · Sister chromatid exchange · Spermatozoon · Animal · Bone Marrow Cells · Cell Nucleus · Crossing Over (Genetics) · Erythrocytes · Female · Lead · Lymphocytes · Male · Mutagenicity Tests · Rabbits · Sister Chromatid Exchange · Sperm Count · Spermatozoa · Support, Non-U.S. Gov't
[Abstract]

11 Genomic analysis suggests higher susceptibility of children to air pollution
article 2008    
Author: Leeuwen, D.M. van · Pedersen, M. · Hendriksen, P.J.M. · Boorsma, A. · Herwijnen, M.H.M. van · Gottschalk, R.W.H. · Kirsch-Volders, M. · Knudsen, L.E. · Šrám, R.J. · Bajak, E. · Delft, J.H.M. van · Kleinjans, J.C.S.
Keywords: Health · Physiological Sciences · transcriptome · adult · air pollution · article · blood analysis · cancer risk · cancer susceptibility · child · child health · controlled study · Czech Republic · data analysis · environmental exposure · environmental health · female · gene expression · gene expression profiling · genomics · human · immune response · male · micronucleus · nucleosome · parent · priority journal · Adult · Air Pollution · Child · Czech Republic · Female · Gene Expression Profiling · Gene Expression Regulation · Genetic Predisposition to Disease · Humans · Male · Nuclear Family · Parents · Receptors, Chemokine · RNA · RNA Splicing
[Abstract]

12 Biological effect markers for exposure to carcinogenic compound and their relevance for risk assessment
article 1998    
Author: Delft, J.H.M. van · Baan, R.A. · Roza, L.
Keywords: Nutrition · Biomarker · Cancer mortality · Cytogenetic damage · DNA adduct · Aromatic compound · Biological marker · Cytostatic agent · Ethylene oxide derivative · Hydrocarbon · Pesticide · Animal tissue · Cancer mortality · Cancer risk · Carcinogenicity · Cell heterogeneity · Chromosome aberration · Cytogenetics · Dna adduct · Human · Human tissue · Micronucleus · Nonhuman · Pathophysiology · Population exposure · Review · Risk assessment · Animals · Carcinogens · Chromosome Aberrations · DNA Adducts · Epidemiologic Methods · Genetic Markers · Humans · Mutation · Neoplasms · Neoplasms, Experimental · Occupational Exposure · Risk Assessment · Tumor Markers, Biological
[Abstract]

13 UV-induced effects
article 2005    
Author: Liebsch, M. · Spielmann, H. · Pape, W. · Krul, C. · Deguercy, A. · Eskes, C.A.M.
Keywords: Health · Physiological Sciences · cosmetic · hypoxanthine phosphoribosyltransferase · acute toxicity · allergenicity · animal testing replacement · cell line · chromosome aberration · comet assay · DNA damage · gene mutation · genotoxicity · human · in vivo study · micronucleus · model · nonhuman · photosensitization · phototoxicity · point mutation · priority journal · radiation exposure · radiation hazard · review · standardization · ultraviolet A radiation · ultraviolet radiation · validation process · Animal Testing Alternatives · Animals · Cell Line · Consumer Product Safety · Cosmetics · Dermatitis, Photoallergic · Dermatitis, Phototoxic · DNA · DNA Damage · Drug Stability · Erythrocytes · European Union · Hemolysis · Humans · Mutagenicity Tests · Mutagens · Photosensitizing Agents · Skin · Skin Irritancy Tests · Ultraviolet Rays · Animalia
[Abstract]

14 Biological monitoring the exposure to polycyclic aromatic hydrocarbons of coke oven workers in relation to smoking and genetic polymorphisms for GSTM1 GSTT1
article 2001    
Author: Delft, J.H.M. van · Steenwinkel, M.-J.S.T. · Asten, J.G. van · Vogel, N. de · Bruijntjes-Rozier, T.C.D.M. · Schouten, T. · Cramers, P. · Maas, L. · Herwijnen, M.H. van · Schooten, F.-J. van · Hopmans, P.M.J.
Keywords: Biology · 1-OHpyr: 1-hydroxypyrene · GST: glutathione S-transferase · HFC: cells with a high frequency of SCE · MN: micronuclei · PAH: polycyclic aromatic hydrocarbons · SCE: sister-chromatid exchange · 1 Hydroxypyrene · Glutathione transferase · Polycyclic aromatic hydrocarbon · Adult · Biological monitoring · Cancer risk · Chromosome analysis · Coke oven industry · Comet assay · Controlled study · DNA adduct · DNA strand breakage · Endothelium cell · Genetic polymorphism · Human · Industrial worker · Industry · Lung cancer · Lymphocyte · Male · Micronucleus test · Multivariate analysis · Normal human · Occupational exposure · Priority journal · Sister chromatid exchange · Smoking · Urine level · Adult · Coke · DNA Adducts · Glutathione Transferase · Humans · Middle Aged · Multivariate Analysis · Occupational Exposure · Polycyclic Hydrocarbons, Aromatic · Polymorphism, Genetic · Sister Chromatid Exchange · Smoking
[Abstract]

15 Towards an alternative testing strategy for nanomaterials used in nanomedicine: Lessons from NanoTEST
article 2015    
Author: Dusinska, M. · Boland, S. · Saunders, M. · Juillerat-Jeanneret, L. · Tran, L. · Pojana, G. · Marcomini, A. · Volkovova, K. · Tulinska, J. · Knudsen, L.E. · Gombau, L. · Whelan, M. · Collins, A.R. · Marano, F. · Housiadas, C. · Bilanicova, D. · Halamoda Kenzaoui, B. · Correia Carreira, S. · Magdolenova, Z. · Fjellsbo, L.M. · Huk, A. · Handy, R. · Walker, L. · Barancokova, M. · Bartonova, A. · Burello, E. · Castell, J. · Cowie, H. · Drlickova, M. · Guadagnini, R. · Harris, G. · Harju, M. · Heimstad, E.S. · Hurbankova, M. · Kazimirova, A. · Kovacikova, Z. · Kuricova, M. · Liskova, A. · Milcamps, A. · Neubauerova, E. · Palosaari, T. · Papazafiri, P. · Pilou, M. · Poulsen, M.S. · Ross, B. · Runden-Pran, E. · Sebekova, K. · Staruchova, M. · Vallotto, D. · Worth, A.
Keywords: Biology · Hazard assessment · in vitro · Nanoparticles · NanoTEST · Testing strategy · Nanomaterial · Adsorption · Bioavailability · Cell activation · Cellular distribution · Chemical composition · Concentration (parameters) · Crystal structure · Dispersion · Hazard assessment · High throughput screening · Hydrophobicity · Material coating · Micronucleus test · Molecular interaction · Nanomedicine · Neutron scattering · Oxidative stress · Particle size · PH · Physical chemistry · Quantitative structure activity relation · Risk assessment · Salinity · Solubility · Standard · Surface charge · Surface property · Temperature · Toxicity assay · Toxicity testing · Transport assay · Transport kinetics · Water hardness · Animalia · Biomedical Innovation · Healthy Living · Life · RAPID - Risk Analysis for Products in Development · ELSS - Earth, Life and Social Sciences
[Abstract]

16 Effect of eugenol on the genotoxicity of established mutagens in the liver
article 1996    
Author: Rompelberg, C.J.M. · Evertz, S.J.C.J. · Bruijntjes-Rozier, G.C.D.M. · Heuvel, P.D. van den · Verhagen, H.
Keywords: Toxicology · aflatoxin b1 · benzo[a]pyrene · dimethylbenz[a]anthracene · eugenol · mutagenic agent · animal experiment · animal tissue · article · controlled study · genotoxicity · hepatoma cell · human · human cell · liver · male · metabolic activation · mutagenicity · nonhuman · oral drug administration · rat · salmonella typhimurium · unscheduled dna synthesis · 9,10-Dimethyl-1,2-benzanthracene · Aflatoxin B1 · Animals · Antimutagenic Agents · Benzo(a)pyrene · Carcinoma, Hepatocellular · Cytochrome P-450 Enzyme System · DNA · Electrophoresis, Agar Gel · Eugenol · Glutathione Transferase · Humans · Liver · Liver Neoplasms · Male · Micronucleus Tests · Mutagenicity Tests · Mutagens · Rats · Rats, Wistar · Salmonella typhimurium · Tumor Cells, Cultured
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 16 of 16 found. | Sort by date