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1 Neural progenitor cells as models for high-throughput screens of developmental neurotoxicity: State of the science
article 2010    
Author: Breier, J.M. · Gassmann, K. · Kayser, R. · Stegeman, H. · Groot, D.de · Fritsche, E. · Shafer, T.J.
Keywords: Biology · Biotechnology · Cell culture · Developmental neurotoxicity screening · High-throughput screening · Neuroprogenitor cells · Neurosphere · Stem cell
[Abstract]

2 Neurobehavioral effects of cyclohexane in rat and human
article 2009    
Author: Lammers, J.H.C.M. · Emmen, H.H. · Muijser, H. · Hoogendijk, E.M.G. · McKee, R.H. · Owen, D.E. · Kulig, B.M.
Keywords: Biology · Toxicology and Applied Pharmacology · Behavioral assessments · Central nervous system effects · Cyclohexane · Solvent neurotoxicity
[Abstract]

3 Evaluation of potential neurotoxic effects of occupational exposure to (L)-Lactates
article 2001    
Author: Clary, J.J. · Feron, V.J. · Velthuijsen, J.A. van
Keywords: Toxicology · Chronic neurotoxicity · Chronic toxic encephalopathy · Lactate esters · Organo psycho syndrome · Solvents · 2 ethylhexanol · 2 propanol · alcohol · butanol · isobutanol · lactic acid derivative · methanol · propanol · animal experiment · article · brain disease · disease association · hydrolysis · mouse · neurotoxicity · nonhuman · occupational exposure · priority journal · rat · risk assessment · toxicity testing · Alcohols · Animals · Esters · Humans · Hydrolysis · Lactates · Neurotoxicity Syndromes · No-Observed-Adverse-Effect Level · Occupational Exposure · Solvents · Toxicity Tests · Volatilization
[Abstract]

4 Regulatory developmental neurotoxicity testing: A model study focussing on conventional neuropathology endpoints and other perspectives
article 2005    
Author: Groot, D.M.G.de · Bos-Kuijpers, M.H.M. · Kaufmann, W.S.H. · Lammers, J.H.C.M. · O'Callaghan, J.P. · Pakkenberg, B. · Pelgrim, M.T.M. · Waalkens-Berendsen, I.D.H. · Waanders, M.M. · Gundersen, H.J.J.
Keywords: Toxicology · Toxicology and Applied Pharmacology · Methylazoxy methanol acetate (MAM) · Microscopy and linear morphometry · Neuron numbers and stereology · Neuropathology endpoints · OECD 426) · OPPTS 870.8600, EPA · Rat · Regulatory developmental neurotoxicity (DNT) testing (Guidelines OPPTS 870.6300, EPA · methylazoxymethanol acetate · animal model · animal tissue · brain · brain development · brain size · conference paper · controlled study · developmental neurotoxicity testing · dissection · female · morphometrics · nerve cell · neuroanatomy · neuropathology · neurotoxicity · nonhuman · perinatal period · practice guideline · priority journal · qualitative analysis · rat · toxicity testing · Animalia
[Abstract]

5 Zebrafish as potential model for developmental neurotoxicity testing : A mini review
article 2012    
Author: Esch, C. de · Slieker, R. · Wolterbeek, A. · Woutersen, R. · Groot, D. de
Keywords: Biology · Zebrafish · Toxicity screening · Developmental neurotoxicity · Model · Biomedical Innovation · Healthy Living · Life · QS - Quality & Safety · EELS - Earth, Environmental and Life Sciences
[Abstract]

6 Physiologically based pharmacokinetic modeling of cyclohexane as a tool for integrating animal and human test data
article 2009    
Author: Hissink, A.M. · Kulig, B.M. · Kruse, J. · Freidig, A.P. · Verwei, M. · Muijser, H. · Lammers, J.H.C.M. · Mckee, R.H. · Owen, D.E. · Sweeney, L.M. · Salmon, F.
Keywords: Biology · Toxicology and Applied Pharmacology · Acute central nervous system effects · Cross-species extrapolations · Cyclohexane · Occupational exposure limits · Physiologically based pharmacokinetic models · Solvent neurotoxicity toxicokinetics
[Abstract]

7 A neurofunctional test battery for evaluating the effects of long-term exposure to chemicals
article 1989    
Author: Kulig, B.M.
Keywords: Nutrition · Acrylamide · Hexane · Styrene · Animal experiment · Animal model · Chronic toxicity · Inhalation · Learning · Nerve conduction · Neurotoxicity · Nonhuman · Rat · Screening test · Toxicity testing

8 Comprehensive neurotoxicity assessment
article 1996    
Author: Kulig, B.M.
Keywords: Nutrition · Cognitive behavior · Functional observational battery · Motor impairment · Neurotoxicity · Sensory function · Behavior · Cognition · Humans · Neurotoxins · Psychomotor Performance · Risk Assessment · United States · United States Environmental Protection Agency · United States Food and Drug Administration
[Abstract]

9 Fingerprinting of neurotoxic compounds using a mouse embryonic stem cell dual luminescence reporter assay
article 2017    
Author: Colaianna, M. · Ilmjärv, S. · Peterson, H. · Ilse Kern, I. · Julien, S. · Baquié, M. · allocca, G. · Bosgra, S. · Sachinidis, A. · Hengstler, J.G. · Leist, M. · Krause, K.H.
Keywords: Pharmacology · Mouse embryonic stem cells · Neuroactivity · Neurotoxicity · In vitro screening · Neuronal differentiation · Healthy for Life · Healthy Living · Life · RAPID - Risk Analysis for Products in Development · ELSS - Earth, Life and Social Sciences
[PDF] [Abstract]

10 N-alkane neurotoxicity in cultured cerebral cells
article 1981    
Author: Hooisma, J. · Dam, E.W.
Keywords: Biology · 2 Hexanone · Acetonylacetone · Hexane · 2 Hexanol · 2,4 Hexanedione · 2,5 Hexanediol · Abstract report · Cell culture · Central nervous system · In vitro study · Intoxication · Nerve cell · Nervous system · Neurotoxicity · Newborn · Rat
[Abstract]

11 Behavioral effects of exposure to organic solvents in carpet layers
article 1996    
Author: Muijser, H. · Geuskens, R.B.M. · Hooisma, J. · Emmen, H.H. · Kulig, B.M.
Keywords: Nutrition · Neurobehavioral Evaluation System · Neurobehavioral testing · Neurotoxicity · Occupational exposure · Organic solvents · acetic acid ethyl ester · adhesive agent · cyclohexane · heptane · organic solvent · toluene · adult · air sampling · alcohol consumption · conference paper · controlled study · education · human · major clinical study · male · neuropsychological test · neurotoxicity · occupational exposure · priority journal · smoking · Adhesives · Adult · Behavior · Diagnosis, Computer-Assisted · Floors and Floorcoverings · Humans · Male · Neuropsychological Tests · Occupational Exposure · Psychometrics · Psychomotor Performance · Reaction Time · Socioeconomic Factors · Solvents · Time Factors
[Abstract]

12 Model studies for evaluating the neurobehavioral effects of complex hydrocarbon solvents. II. Neurobehavioral effects of white spirit in rat and human
article 2007    
Author: Lammers, J.H.C.M. · Emmen, H.H. · Muijser, H. · Hoogendijk, E.M.G. · McKee, R.H. · Owen, D.E. · Kulig, B.M.
Keywords: Toxicology and Applied Pharmacology · Behavior · Human · Rat · Solvent neurotoxicity · White spirit · 1,2,4 trimethylbenzene · biological marker · decane · hydrocarbon · organic solvent · stoddard solvent · unclassified drug · adult · animal experiment · article · attention · behavior · blood sampling · central nervous system depression · cognition · conditioning · controlled study · correlation analysis · exposure · human · human experiment · learning · male · memory · motor activity · neuropsychological test · neurotoxicity · nonhuman · observational study · priority journal · qualitative analysis · rat · scoring system · species comparison · task performance · visual discrimination · Adult · Affect · Analysis of Variance · Animals · Attention · Behavior, Animal · Body Weight · Discrimination (Psychology) · Humans · Hydrocarbons · Male · Mental Processes · Models, Animal · Motor Activity · Motor Skills · Nervous System · Neuropsychological Tests · Rats · Reaction Time · Solvents · Animalia · Rattus · Rodentia
[Abstract]

13 2D and 3D assessment of neuropathology in rat brain after prenatal exposure to methylazoxymethanol, a model for developmental neurotoxicty
article 2005    
Author: Groot, D.M.G. de · Hartgring, S. · Horst, L. van de · Moerkens, M. · Otto, M. · Bos-Kuijpers, M.H.M. · Kaufmann, W.S.H. · Lammers, J.H.C.M. · O'Callaghan, J.P. · Waalkens-Berendsen, I.D.H. · Pakkenberg, B. · Gundersen, H.G.
Keywords: Biology · Toxicology and Applied Pharmacology · Cerebellum · Developmental neurotoxicity · Hippocampus · Linear morphometry · Methylazoxymethanol · Neuron numbers · Rat · Stereology · methylazoxymethanol · animal experiment · animal model · animal tissue · article · brain development · brain size · brain weight · cell count · cell proliferation · cell structure · cerebellum · controlled study · developmental disorder · evaluation · female · hippocampus · linear system · male · morphometrics · neuropathology · neurotoxicity · nonhuman · pregnancy · prenatal exposure · progeny · pyramidal nerve cell · quantitative analysis · rat · stereology · strength · three dimensional imaging · Abnormalities, Drug-Induced · Animals · Animals, Outbred Strains · Brain · Cell Count · Female · Imaging, Three-Dimensional · Injections, Intraperitoneal · Male · Maternal Exposure · Methylazoxymethanol Acetate · Organ Size · Pregnancy · Prenatal Exposure Delayed Effects · Rats · Rats, Wistar · Specific Pathogen-Free Organisms · Teratogens · Toxicity Tests
[Abstract]

14 Delay and impairment in brain development and function in rat offspring after maternal exposure to methylmercury
article 2013    
Author: Radonjic, M. · Cappaert, N.L.M. · Vries, E.F.J. de · Esch, C.E.F. de · Kuper, F.C. · Waarde, A. van · Dierckx, R.A.J.O. · Wadman, W.J. · Wolterbeek, A.P.M. · Stierum, R.H. · Groot, D.M.G. de
Keywords: Biology · [18F]FDG PET functional imaging · Field potential analysis · Methylmercury · Microarrays · Neurodevelopment · Neurotoxicity · Biomedical Innovation · Healthy Living · Life Triskelion BV Life · MSB - Microbiology and Systems Biology TARA - Toxicology and Risk Assessment QS - Quality & Safety · EELS - Earth, Environmental and Life Sciences TNO Bedrijven
[Abstract]

15 Low level nose-only exposure to the nerve agent soman: Toxicokinetics of soman stereoisomers and cholinesterase inhibition in atropinized guinea pigs
article 1998    
Author: Benschop, H.P. · Trap, H.C. · Spruit, H.E.T. · Wiel, H.J. van der · Langenberg, J.P. · Jong, L.P.A. de
Keywords: Perception · Atropine · Carboxylesterase · Cholinesterase · Animal cell · Blood level · Enzyme inhibition · Exposure · Guinea pig · Inhalation · Male · Neurotoxicity · Nonhuman · Stereoisomerism · Toxicokinetics · Administration, Inhalation · Animals · Carboxylic ester hydrolases · Chemical warfare agents · Dose-response relationship · Drugs · Erythrocytes · Soman · Stereoisomerism · Time factors · Atropine, 51-55-8 · Carboxylesterase, EC 3.1.1.1 · Carboxylic ester hydrolases, EC 3.1.1.- · Soman, 96-64-0
[Abstract]

16 Semi-continuous high speed gas analysis of generated vapors of chemical warfare agents
article 1999    
Author: Trap, H.C. · Langenberg, J.P.
Keywords: Automation · Data acquisition · Nerve agents · Sulfur mustard · Valve injection · Vapor analysis · Mustard gas · Nerve gas · Neurotoxin · Sarin · Soman · Analytic method · Animal experiment · Article · Autoanalysis · Chemical warfare · Chromatography · Gas analysis · Gas chromatography · Guinea pig · Neurotoxicity · Nonhuman · Toxicokinetics · Vapor · Mustard gas, 505-60-2 · Neurotoxin, 39386-17-9 · Sarin, 107-44-8 · Soman, 96-64-0
[Abstract]

17 Behavioural effects and kinetics in brain in response to inhalation of constant or fluctuating toluene concentrations in the rat
article 2005    
Author: Lammers, J.H.C.M. · Asperen, J. van · Groot, D. de · Rijcken, W.R.P.
Keywords: Health Biology · Toxicology and Applied Pharmacology · Motor activity · Peak exposure · Rat · Toluene · Toxicokinetics · Visual discrimination · toluene · animal experiment · animal model · blood level · brain level · concentration response · conference paper · controlled study · exposure · male · motor activity · neurotoxicity · nonhuman · priority journal · rat · toxicokinetics · visual discrimination
[Abstract]

18 Sensitivity of several cell systems to acrylamide
article 1980    
Author: Hooisma, J. · Groot, D.M.G.de · Magchielse, T. · Muijser, H.
Keywords: Pharmacology · Central nervous system · Cytotoxicity · Dose response · Drug response · Endocrine system · Female genital system · Histology · In vitro study · Intoxication · Muscle cell · Nervous system · Neuroblastoma cell · Neurotoxicity · Ovary cell · Rat · Spinal cord · Spinal ganglion · Acrylamides · Animal · Brain · Chickens · Ganglia, Spinal · Mice · Muscles · Neurons · Rabbits · Tissue Culture
[PDF] [Abstract]

19 Effects of prenatal PCB and dioxin background exposure on cognitive and motor abilities in Dutch children at school age
article 2002    
Author: Vreugdenhil, H.J.I. · Lanting, C.I. · Mulder, P.G.H. · Boersma, E.R. · Weisglas-Kuperus, N.
Keywords: Health · Breast feeding · Cognition · Environmental exposure · Intellect · Major clinical study · Maternal blood · Motor performance · Neurotoxicity · Prenatal exposure · Preschool child · Priority journal · School child · Umbilical cord blood · Child · Cognition · Dioxins · Environmental Pollutants · Female · Follow-Up Studies · Humans · Male · Motor Skills · Netherlands · Polychlorinated Biphenyls · Pregnancy · Prenatal Exposure Delayed Effects
[Abstract]

20 Long-term cognitive deficits accompanied by reduced neurogenesis after soman poisoning
article 2009    
Author: Joosen, M.J.A. · Jousma, E. · Boom, T.M. van den · Kuijpers, W.C. · Smit, A.B. · Lucassen, P.J. · Helden, H.P.M. van
Keywords: Toxicology · Learning · Memory · Neurogenesis · Olanzapine · Organophosphate · Soman · acetylcholine · acetylcholinesterase · atropine · doublecortin · olanzapine · soman · animal experiment · animal model · animal tissue · article · body weight · cell survival · cognitive defect · controlled study · corpus striatum · developmental disorder · drug efficacy · drug treatment failure · histopathology · learning disorder · male · maze test · memory disorder · nervous system development · neurotoxicity · nonhuman · osmotic minipump · priority journal · rat · recurrent disease · seizure · Acetylcholine · Acetylcholinesterase · Animals · Atropine · Benzodiazepines · Cholinesterase Reactivators · Corpus Striatum · Hippocampus · Male · Maze Learning · Neurogenesis · Pyridinium Compounds · Rats · Rats, Sprague-Dawley · Seizures · Soman · Animalia · Rattus
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 32 found. Next | Sort by date