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1 Characterization of cytochrome P450 isoenzymes in primary cultures of pig hepatocytes
article 1998    
Author: Monshouwer, M. · Klooster, G.A.E. van 't · Nijmeijer, S.M. · Witkamp, R.F. · Miert, A.S.J.P.A.M. van
Keywords: Nutrition · Cytochrome P450 · Hepatocytes · Induction · Pig · Apoprotein · Beta naphthoflavone · Complementary DNA · Cytochrome p450 isoenzyme · Dexamethasone · Ethoxyresorufin deethylase · Ethylmorphine n demethylase · Messenger RNA · Oxygenase · Phenobarbital · Rifampicin · Animal cell · Controlled study · Enzyme activity · Enzyme analysis · Enzyme induction · Liver cell culture · Nonhuman · RNA analysis · RNA hybridization · Swine · Xenobiotic metabolism
[Abstract]

2 Metabolism of carveol and dihydrocarveol in Rhodococcus erythropolis DCL14
article 2000    
Author: Werf, M.J. van der · Boot, A.M.
Keywords: Nutrition · Carveol · Carvone · Dihydrocarveol · Monoterpene metabolism · Rhodococcus erythropolis · Bacterial enzyme · Carveol · Carvone · Dihydrocarveol · Hexanoic acid derivative · Isomerase · Nicotinamide adenine dinucleotide · Oxepane derivative · Oxidoreductase · Oxygenase · Unclassified drug · Bacterial metabolism · Controlled study · Enzyme activity · Nonhuman · Priority journal · Rhodococcus · Stereoisomerism · 2,6-Dichloroindophenol · Alcohol Oxidoreductases · Anaerobiosis · Biodegradation, Environmental · Cyclohexenes · Hydrolases · Isomerases · Monoterpenes · Rhodococcus · Stereoisomerism · Terpenes · Actinobacteria (class) · Bacteria (microorganisms) · Erythropolis · Rhodococcus erythropolis · Uncultured actinomycete
[Abstract]

3 Recombinant Saccharomyces cerevisiae expressing P450 in artificial digestive systems : A model for biodetoxication in the human digestive environment
article 2003    
Author: Blanquet, S. · Meunier, J.P. · Minekus, M. · Marol-Bonnin, S. · Alric, M.
Keywords: Health Nutrition · Physiological Sciences · Digestive system · Disease control · Microbiology · Microorganisms · Biodrugs · Yeast · Cinnamate 4 monooxygenase · Cinnamic acid · cytochrome P450 · Oxygenase · Para coumaric acid · Unclassified drug · Biotechnology · Drug development · Microbiology · Article · Biotransformation · Computer simulation · Detoxification · Digestion · Digestive system · Duodenum · Enzyme activity · Gastrointestinal tract · Ileum · Incubation time · Intestine secretion · Jejunum · Quantitative analysis · Saccharomyces cerevisiae · Small intestine · Stomach secretion · Survival rate · Yeast · Genetic Engineering · Helianthus · Humans · Metabolic Detoxication, Drug · Mixed Function Oxygenases · Models, Biological · Saccharomyces cerevisiae · Trans-Cinnamate 4-Monooxygenase · Saccharomyces cerevisiae
[PDF] [Abstract]

4 Insulin suppresses bile acid synthesis in cultured rat hepatocytes by down-regulation of cholesterol 7α-hydroxylase and sterol 27-hydroxylase gene transcription
article 1995    
Author: Twisk, J. · Hoekman, M.F.M. · Lehmann, E.M. · Meijer, P. · Mager, W.H. · Princen, H.M.G.
Keywords: Biology · cholesterol 7alpha monooxygenase · insulin · oxygenase · sterol 27 hydroxylase · unclassified drug · animal cell · article · bile acid synthesis · controlled study · down regulation · enzyme activity · gene expression regulation · hormone action · liver cell culture · nonhuman · transcription regulation · Animal · Bile Acids and Salts · Cells, Cultured · Chloramphenicol O-Acetyltransferase · Cholesterol 7-alpha-Hydroxylase · Cytochrome P-450 Enzyme System · Down-Regulation · Gene Expression Regulation, Enzymologic · Insulin · Liver · Male · Membrane Glycoproteins · Nuclear Proteins · Rats · Rats, Wistar · RNA, Messenger · Steroid Hydroxylases · Support, Non-U.S. Gov't · Transcription, Genetic · Transfection
[Abstract]

5 Isolation and characterization of Alicycliphilus denitrificans strain BC, which grows on benzene with chlorate as the electron acceptor
article 2008    
Author: Weelink, S.A.B. · Tan, N.C.G. · Broeke, H. ten · Kieboom, C. van den · Doesburg, W. van · Langenhoff, A.A.M. · Gerritse, J. · Junca, H. · Stams, A.J.M.
Keywords: Geosciences · Biochemistry · Biodegradation · Catalysts · Cell culture · Degradation · Encoding (symbols) · Enzymes · Gene encoding · Genes · Nitrates · Oxygen · Oxygenation · Proteins · Benzene biodegradations · Benzene degradations · Biochemical datum · Cyclohexanol · Dioxygenase enzymes · Dismutase · Dismutation · Electron acceptors · Encoding · Enrichment cultures · External- · Gene sequences · Genes encoding · In cells · Isolation and characterizations · Monooxygenase · Monooxygenations · Organic molecules · Oxygenase · Oxygenases · Pcr primers · Primer sets · Short rods · Benzene · bacterial enzyme · benzene · benzene oxygenase · catechol · catechol 1,2 dioxygenase · chlorate · chlorite dismutase · estradiol dioxygenase · nitrate · oxygenase · unclassified drug · bacterium · benzene · biochemistry · biodegradation · catabolism · chlorite · denitrification · detection method · electron · enzyme activity · gene expression · mutation · nitrate · oxic conditions · oxygen · polymerase chain reaction · Alicycliphilus denitrificans · article · bacterial growth · bacterial strain · bacterium isolate · biodegradation · electron transport · energy yield · gene amplification · gene sequence · genetic code · nonhuman · nucleotide sequence · oxygenation · phylogeny · polymerase chain reaction · Proteobacteria · unindexed sequence · Bacterial Proteins · Benzene · Chlorates · Comamonadaceae · Dioxygenases · DNA, Bacterial · DNA, Ribosomal · Genes, rRNA · Locomotion · Mixed Function Oxygenases · Molecular Sequence Data · Nitrates · Nitrites · Nitrogen · Oxidoreductases · Oxygen · Phylogeny · Polymerase Chain Reaction · RNA, Bacterial · RNA, Ribosomal, 16S · Sequence Analysis, DNA · Sequence Homology, Nucleic Acid · Alicycliphilus denitrificans · Bacteria (microorganisms) · Negibacteria
[Abstract]

6 Toxicogenomics of bromobenzene hepatotoxicity: A combined transcriptomics and proteomics approach
article 2003    
Author: Heijne, W.H.M. · Stierum, R.H. · Slijper, M. · Bladeren, P.J. van · Ommen, B. van
Keywords: Toxicology Health · Physiological Sciences · Bromobenzene · cDNA microarray · Hepatotoxicity · Proteomics · Toxicogenomics · Transcriptomics · alpha glutamylcysteine synthetase · bromobenzene · cathepsin L · enzyme · epoxide hydrolase · glutathione · glutathione transferase · heme oxygenase · messenger RNA · peroxiredoxin · proteasome · unclassified drug · animal experiment · animal model · animal tissue · article · controlled study · enzyme activity · enzyme induction · enzyme regulation · enzyme subunit · gene control · gene expression · gene identification · gene induction · genomics · glutathione metabolism · liver toxicity · lysosome · male · nonhuman · nucleotide sequence · oxidative stress · priority journal · protein content · protein degradation · protein depletion · protein expression · protein synthesis · proteomics · rat · RNA analysis · tissue level · unindexed sequence · weight reduction · Animals · Bromobenzenes · Liver · Male · Oligonucleotide Array Sequence Analysis · Pharmacogenetics · Proteomics · Rats · Rats, Wistar · Transcription, Genetic
[Abstract]

7 Keratinocyte gene expression profiles discriminate sensitizing and irritating compounds
article 2010    
Author: Briel, R.J. van de · Pennings, J.L.A. · Baken, K.A. · Pronk, T.E. · Boorsma, A. · Gottschalk, R. · Loveren, H. van
Keywords: Biology · Biomedical Research · Gene profiling · HaCaT · Irritant oxidative stress · Keratinocytes · Sensitizer · 1 chloro 2,4 dinitrobenzene · 2 propanol · benzoic acid · cinnamyl alcohol · collagen type 16 · disulfiram · dodecyl sulfate sodium · eugenol · ferritin · ferrochelatase · glucose 6 phosphate dehydrogenase · glucuronosyltransferase 1A6 · glutamate cysteine ligase · glutathione reductase · heat shock protein · heme oxygenase 1 · hexane · interleukin 6 receptor · irritant agent · isoeugenol · lactic acid · mitogen activated protein kinase · nickel sulfate · phosphogluconate dehydrogenase · salicylic acid methyl ester · thioredoxin 2 · thioredoxin reductase 1 · thioredoxin reductase 2 · transcription factor Nrf2 · article · cell viability · gene control · gene expression profiling · human · human cell · human cell culture · in vitro study · keratinocyte · oxidative stress · random forest · sensitization · support vector machine
[Abstract]

8 Suppression of sterol 27-hydroxylase mRNA and transcriptional activity by bile acids in cultured rat hepatocytes
article 1995    
Author: Twisk, J. · Wit, E.C.M. de · Princen, H.M.G.
Keywords: Biology · bile acid · chenodeoxycholic acid · cholesterol 7alpha monooxygenase · cholic acid · deoxycholic acid · lithocholic acid · messenger rna · oxygenase · sterol · taurocholic acid · animal cell · article · bile acid synthesis · cholesterol metabolism · controlled study · enzyme inhibition · gene repression · liver cell culture · nonhuman · priority journal · rat · transcription regulation · Adenosine Triphosphate · Animal · Bile Acids and Salts · Cells, Cultured · Cholesterol 7-alpha-Hydroxylase · Cytochrome P-450 Enzyme System · Dose-Response Relationship, Drug · Down-Regulation · Gene Expression Regulation, Enzymologic · Liver · Male · Mitochondria · Oxidoreductases · Rats · Rats, Wistar · RNA, Messenger · Steroid Hydroxylases · Support, Non-U.S. Gov't · Taurocholic Acid · Transcription, Genetic
[Abstract]

9 Regulation of expression of the Aspergillus niger benzoate para-hydroxylase cytochrome P450 system
article 2000    
Author: Brink, J.M. van den · Punt, P.J. · Gorcom, R.F.M. van · Hondel, C.A.M.J.J. van den
Keywords: Nutrition · Aspergillus niger · Benzoate · Cytochrome P450 · Post-transcriptional regulation · Benzoic acid · Cytochrome P450 · Cytochrome P450 reductase · Oxygenase · Aspergillus niger · DNA responsive element · Enzyme analysis · Enzyme regulation · Gene expression regulation · Gene function · Gene induction · Genetic transcription · Hydroxylation · Nonhuman · Nucleotide sequence · Priority journal · Promoter region · Protein induction · Amino Acid Sequence · Aspergillus niger · Base Sequence · Benzoates · Enzyme Induction · Gene Expression Regulation, Bacterial · Gene Expression Regulation, Enzymologic · Mixed Function Oxygenases · Molecular Sequence Data · NADH, NADPH Oxidoreductases · NADPH-Ferrihemoprotein Reductase · Oxygenases · Promoter Regions (Genetics) · Recombinant Fusion Proteins · Restriction Mapping · Sequence Alignment · Sequence Homology, Amino Acid · Transcription, Genetic · Aspergillus niger · Eukaryota · Fungi
[Abstract]

10 Xenobiotic metabolism in human skin and 3D human skin reconstructs: A review
article 2007    
Author: Gibbs, S. · Sandt, J.J.M. van de · Merk, H.F. · Lockley, D.J. · Pendlington, R.U. · Pease, C.K.
Keywords: Biology · 3D skin reconstructs · Cytochrome P450 · IDO expression · In vitro skin absorption · Microarray · Peptidases · 1 chloro 2,4 dinitrobenzene · 2 nitro 1,4 phenylenediamine · 4 aminophenol · alcohol dehydrogenase · aldehyde dehydrogenase · alpha tocopherol · atrazine · azo reductase · carnitine · cinnamaldehyde · cinnamyl alcohol · clobetasol propionate · cytochrome P450 · esterase · hydrogen peroxide · messenger RNA · nicotinic acid ethyl ester · oxygenase · phenylenediamine · propoxur · propranolol · resorufin · retinoic acid · retinol palmitate · T 2 toxin · toxic substance · triclosan · triolein · unindexed drug · xenobiotic agent · biotransformation · chemical carcinogenesis · environmental exposure · enzyme assay · ex vivo study · human · immunohistochemistry · in vitro study · nonhuman · Northern blotting · occupational exposure · protein expression · protein function · review · skin absorption · skin allergy · skin cancer · skin carcinogenesis · skin inflammation · skin sensitization · skin toxicity · toxicokinetics · Western blotting · xenobiotic metabolism · Biotransformation · Humans · Models, Biological · Skin · Xenobiotics
[Abstract]

Search results also available in MS Excel format.

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