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1 Plasma clearance of urokinase-type plasminogen activator
article 1998    
Author: Kaaden, M.E. van der · Rijken, D.C. · Berkel, T.J.C. van · Kuiper, J.
Keywords: Health · urokinase receptor · blood clot lysis · drug receptor binding · endothelium cell · extracellular matrix · glycosylation · internalization · liver metabolism · nonhuman · plasma clearance · plasminogen activation · priority journal · protein isolation · review

2 Apolipoprotein CI enhances the biological response to LPS via the CD14/TLR4 pathway by LPS-binding elements in both its N- and C-terminal helix
article 2010    
Author: Berbé, J.F.P. · Coomans, C.P. · Westerterp, M. · Romijn, J.A. · Havekes, L.M. · Rensen, P.C.N.
Keywords: Biology · Biomedical Research · Endotoxins · Inflammation · Mice · Peptide · Tnfα · Apolipoprotein C1 · CD14 antigen · Lipopolysaccharide · Lipopolysaccharide binding protein · Toll like receptor 4 · Tumor necrosis factor alpha · Amino terminal sequence · Animal cell · Animal experiment · Carboxy terminal sequence · Controlled study · Cytokine release · Electrophoretic mobility · Mouse · Nonhuman · Peritoneum macrophage · Plasma clearance · Signal transduction
[PDF] [Abstract]

3 Interaction of mutants of tissue-type plasminogen activator with liver cells: Effect of domain deletions
article 1996    
Author: Kuiper, J. · Hof, A. van 't · Otter, M. · Biessen, E.A.L. · Rijken, D.C. · Berkel, T.J.C. van
Keywords: Biology · tissue plasminogen activator · animal cell · animal experiment · article · controlled study · deletion mutant · drug clearance · drug structure · gene cassette · kringle domain · liver cell · male · molecular interaction · nonhuman · plasma clearance · priority journal · protein domain · rat · Animals · Binding Sites · Biological Transport, Active · Endothelium · Epidermal Growth Factor · Half-Life · Kringles · Liver · Male · Molecular Structure · Mutation · Rats · Rats, Wistar · Tissue Plasminogen Activator · Animalia
[Abstract]

4 Plasma plasminogen activator inhibitor-1 level is not regulated by the hepatic low-density lipoprotein receptor-related protein [2]
article 2007    
Author: Hu, L. · Bovenschen, N. · Havekes, L.M. · Vlijmen, B.J.M. van · Tamsma, J.T.
Keywords: Biology · Biomedical Research · adenovirus vector · beta galactosidase · complementary DNA · liver protein · low density lipoprotein receptor related protein · plasminogen activator inhibitor 1 · protein inhibitor · receptor associated protein · serum amyloid A · animal experiment · animal model · controlled study · half life time · in vivo study · letter · mouse · nonhuman · plasma clearance · priority journal · protein blood level · protein expression · protein function · protein protein interaction · regulatory mechanism · Animals · LDL-Receptor Related Protein 1 · Mice · Mice, Knockout · Pharmacokinetics · Plasminogen Activator Inhibitor 1

5 Clearance of coagulation factor VIII in very low-density lipoprotein receptor knockout mice
article 2004    
Author: Bovenschen, N. · Dijk, K.W. van · Havekes, L.M. · Mertens, K. · Vlijmen, B.J.M. van
Keywords: Biology · Biomedical Research · Clearance · Factor VIII · Knockout mice · Low-density lipoprotein receptor-related protein · Very low-density lipoprotein receptor · blood clotting factor 8 · cholesterol · triacylglycerol · very low density lipoprotein receptor · animal experiment · article · catabolism · cholesterol blood level · controlled study · knockout mouse · male · mouse · nonhuman · plasma clearance · priority journal · triacylglycerol blood level · Animals · Factor VIII · Integrases · LDL-Receptor Related Proteins · Mice · Mice, Knockout · Mice, Transgenic · Receptors, LDL
[Abstract]

6 Cholesteryl ester transfer protein inhibition: Effect on reverse cholesterol transport?
article 2006    
Author: Rensen, P.C.N. · Havekes, L.M.
Keywords: Biology · Biomedical Research · 2 methylpropanethioic acid s [2 [1 (2 ethylbutyl)cyclohexylcarboxamido]phenyl] ester · Atorvastatin · Cholesterol ester transfer protein inhibitor · Fibric acid derivative · High density lipoprotein cholesterol · Hydroxymethylglutaryl coenzyme A reductase inhibitor · Nicotinic acid · Torcetrapib · Atherosclerosis · Cholesterol transport · Clinical trial · Drug efficacy · Drug mechanism · Dyslipidemia · Editorial · Ischemic heart disease · Nonhuman · Plasma clearance · Protein expression · Reverse cholesterol transport · Animals · Biological Transport · Cardiovascular Diseases · Carrier Proteins · Cholesterol Ester Transfer Proteins · Cholesterol Esters · Cholesterol, HDL · Glycoproteins · Humans · Lipid Metabolism · Lipoproteins, HDL · Rabbits · Risk Factors
[Abstract]

7 P-glycoprotein-deficient mice have proximal tubule dysfunction but are protected against ischemic renal injury
article 2007    
Author: Huls, M. · Kramers, C. · Levtchenko, E.N. · Wilmer, M.J.G. · Dijkman, H.B.P.M. · Kluijtmans, L.A.J. · Hoorn, J.W.A. van der · Russel, F.G.M. · Masereeuw, R.
Keywords: Biology · ABC transporter · Drug transporter · Ischemia-reperfusion · Kidney dysfunction · ABC transporter · adenosine triphosphate · amino acid · calcium · creatinine · glucose · glycoprotein P · lithium · protein · sodium · amino acid urine level · animal model · animal tissue · calcium excretion · controlled study · creatinine clearance · diuresis · electron microscopy · glomerulus filtration rate · glucosuria · kidney blood flow · kidney cortex · kidney injury · kidney ischemia · kidney proximal tubule · kidney tubule necrosis · knockout mouse · oxidative stress · plasma clearance · priority journal · protein expression · protein function · sodium excretion · upregulation · urinary excretion · Amino Acids · Animals · Calcium · Diuresis · Fluorescent Antibody Technique · Glomerular Filtration Rate · Glycosuria · Immunohistochemistry · Ischemia · Kidney Failure, Acute · Kidney Tubules, Proximal · Male · Mice · Mice, Inbred Strains · Mice, Knockout · Mitochondria · P-Glycoprotein · Proteinuria · Renal Circulation · Sodium
[Abstract]

8 The VLDL receptor plays a major role in chylomicron metabolism by enhancing LPL-mediated triglyceride hydrolysis
article 2004    
Author: Goudriaan, J.R. · Espirito Santo, S.M.S. · Voshol, P.J. · Teusink, B. · Dijk, K.W. van · Vlijmen, B.J.M. van · Romijn, J.A. · Havekes, L.M. · Rensen, P.C.N.
Keywords: Biology · Biomedical Research · Adipose tissue · Free fatty acids · Lipoprotein lipase · Postprandial lipid metabolism · Transgenic mice · Very low density lipoprotein-like emulsion · Albumin · Carbon 14 · Chylomicron · Fatty acid · Lipoprotein lipase · Triacylglycerol · Very low density lipoprotein · Very low density lipoprotein receptor · Animal experiment · Animal tissue · Bolus injection · Continuous infusion · Controlled study · Diet restriction · Emulsion · Enzyme activity · Fatty acid transport · Female · Half life time · Lipid blood level · Lipid hydrolysis · Lipid metabolism · Lipolysis · Mouse · Nonhuman · Plasma clearance · Postprandial state · Protein expression · Transgenic mouse · Adipose Tissue · Albumins · Animals · Chylomicrons · Fatty Acids, Nonesterified · Mice · Receptors, LDL · Triglycerides
[PDF] [Abstract]

9 Inhibition of mannose receptor-mediated-clearance of tissue-type plasminogen activator (t-PA) by dextran : A new explanation for its antithrombotic effect
article 1997    
Author: Noorman, F. · Barrett-Bergshoeff, M.M. · Bekkers, M. · Emeis, J.J. · Rijken, D.C.
Keywords: Biology · Anticoagulant agent · Dextran · Dextran 40 · Dextran 70 · Low density lipoprotein receptor · Mannose receptor · Tissue plasminogen activator · Animal experiment · Bolus injection · Controlled study · Deep vein thrombosis · Drug infusion · Drug mechanism · Human · Human cell · Macrophage · Male · Monocyte · Nonhuman · Plasma clearance · Priority journal · Protein blood level · Rat · Thrombogenesis · Acetylgalactosamine · Animals · Cells, Cultured · Depression, Chemical · Dextrans · Fibrinolytic Agents · Glucose · Humans · Lectins, C-Type · Macrophages · Male · Mannose · Mannose-Binding Lectins · Metabolic Clearance Rate · Protein Binding · Rats · Rats, Wistar · Receptors, Cell Surface · Receptors, LDL · Recombinant Proteins · Tissue Plasminogen Activator
[Abstract]

10 Effect of methylglyoxal on the physico-chemical and biological properties of low-density lipoprotein
article 1998    
Author: Schalkwijk, C.G. · Vermeer, M.A. · Stehouwer, C.D.A. · Koppele, J. te · Princen, H.M.G. · Hinsbergh, V.W.M. van
Keywords: Biology · Advanced glycation end product · Diabetes · Low density lipoprotein · Methylglyoxal · Arginine · Cholesterol ester · Cytochrome c · Iodine 125 · Low density lipoprotein · Low density lipoprotein receptor · Lysine · Methylglyoxal · Monocyte chemotactic protein 1 · Oxidized low density lipoprotein · Superoxide · Vasculotropin · Controlled study · Fluorescence · Human · Human cell · Isotope labeling · Lipid metabolism · Macrophage · Plasma clearance · Priority journal · Receptor affinity · Animals · Cell Line · Chemistry, Physical · Cytochrome c Group · Electrochemistry · Endothelium, Vascular · Fibroblasts · Humans · Lipid Peroxidation · Lipid Peroxides · Lipoproteins, LDL · Macrophages · Malondialdehyde · Mice · Oxidation-Reduction · Pyruvaldehyde · Receptors, LDL · Superoxides · Thiobarbituric Acid Reactive Substances · Murinae
[Abstract]

11 Dietary sphingolipids lower plasma cholesterol and triacylglycerol and prevent liver steatosis in APOE*3Leiden mice
article 2006    
Author: Duivenvoorden, I. · Voshol, P.J. · Rensen, P.C.N. · Duyvenvoorde, W. van · Romijn, J.A. · Emeis, J.J. · Havekes, L.M. · Nieuwenhuizen, W.F.
Keywords: Health Biology · Food technology · APOE*3Leiden mice · Cholesterol · Free fatty acids · Sphingolipids · Steatosis · Triacylglycerol · alanine aminotransferase · amyloid · apolipoprotein E3 · cholesterol · cholesterol ester · fatty acid · messenger RNA · phytosphingosine · RNA · sphingolipid · triacylglycerol · apolipoprotein E · apolipoprotein E3 (Leidein) · very low density lipoprotein · animal experiment · animal model · animal tissue · article · cholesterol blood level · cholesterol metabolism · controlled study · diet supplementation · dose response · drug effect · drug structure · fatty liver · female · gene expression · hepatitis · lipogenesis · lipolysis · mouse · nonhuman · nutritional assessment · plasma clearance · prophylaxis · animal · blood · chemistry · cholesterol intake · enzymology · feces · genetics · intestine absorption · lipid metabolism · liver · metabolism · physiology · randomization · transgenic mouse · Animals · Apolipoprotein E3 · Apolipoproteins E · Cholesterol · Cholesterol, Dietary · Dose-Response Relationship, Drug · Fatty Acids, Nonesterified · Fatty Liver · Feces · Female · Gene Expression · Intestinal Absorption · Lipid Metabolism · Lipolysis · Lipoproteins, VLDL · Liver · Mice · Mice, Transgenic · Random Allocation · RNA · Sphingolipids · Triglycerides
[Abstract]

12 Niacin increases HDL by reducing hepatic expression and plasma levels of cholesteryl ester transfer protein in APOE*3Leiden.CETP mice
article 2008    
Author: Hoorn, J.W.A. van der · Haan, W. de · Berbée, J.P.P. · Havekes, L.M. · Jukema, J.W. · Rensen, P.C. · Princen, H.M.G.
Keywords: APOE*3Leiden.CETP transgenic mice · CETP · HDL-cholesterol · Hyperlipidemia · Niacin · cholesterol · cholesterol ester transfer protein · high density lipoprotein · high density lipoprotein cholesterol · low density lipoprotein cholesterol · nicotinic acid · triacylglycerol · antilipemic agent · CETP protein, human · messenger RNA · animal experiment · animal model · animal tissue · blood level · cholesterol blood level · controlled study · dose response · drug dose comparison · drug mechanism · female · gene activity · gene expression regulation · hypercholesterolemia · hypertriglyceridemia · kidney · lipid transport · lipoprotein blood level · liver · mouse · mouse strain · nonhuman · particle size · plasma clearance · priority journal · protein blood level · protein function · protein transport · transgenic mouse · triacylglycerol blood level · atherosclerosis · bile · blood · chemistry · disease model · drug effect · fat intake · feces · genetics · metabolism · time · upregulation · Animals · Antilipemic Agents · Apolipoprotein A-I · Apolipoprotein E3 · Atherosclerosis · Bile · Cholesterol Ester Transfer Proteins · Cholesterol, HDL · Dietary Fats · Disease Models, Animal · Dose-Response Relationship, Drug · Feces · Female · Humans · Liver · Mice · Mice, Transgenic · Niacin · RNA, Messenger · Time Factors · Triglycerides · Up-Regulation
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 12 of 12 found. | Sort by date