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1 Putative role of lysyl hydroxylation and pyridinoline cross-linking during adolescence in the occurrence of osteoarthritis at old age
article 2002    
Author: Bank, R.A. · Verzijl, N. · Lafeber, F.P.J.G. · Tekoppele, J.M.
Keywords: Health Biology · Biomedical Research · Collagen · Fatigue · Hydroxylysine · Osteoarthritis · Pyridinoline · collagen · hydroxylysine · pentosidine · pyridinoline · adolescence · adult · aged · article · articular cartilage · cartilage degeneration · clinical article · collagen synthesis · controlled study · cross linking · fatigue · femur condyle · human · human tissue · hydroxylation · knee osteoarthritis · onset age · pathogenesis · priority journal · senescence · stress · stress strain relationship · Aged · Aged, 80 and over · Amino Acids · Arginine · Case-Control Studies · Collagen · Cross-Linking Reagents · Humans · Hydroxylysine · Lysine · Middle Aged · Osteoarthritis, Knee
[Abstract]

2 Minoxidil exerts different inhibitory effects on gene expression of lysyl hydroxylase 1, 2, and 3: Implications for collagen cross-linking and treatment of fibrosis
article 2005    
Author: Zuurmond, A.M. · Slot van der-Verhoeven, A.J. · Dura, E.A. van · Groot, J. de · Bank, R.A.
Keywords: Biology · Biomedical Research · Lysyl hydroxylase · Pyridinoline cross-links · Messenger RNA · Procollagen lysine 2 oxoglutarate 5 dioxygenase · Pyridinoline · Concentration response · Controlled study · Dose time effect relation · Drug activity · Drug inhibition · Drug sensitivity · Enzyme specificity · Enzyme substrate · Extracellular matrix · Fibroblast culture · Human cell · Protein cross linking · Protein structure · Skin fibrosis · 2-Aminoadipic Acid · Cells, Cultured · Chromatography, High Pressure Liquid · Collagen · Fibrosis · Gene Expression Regulation, Enzymologic · Humans · Hydroxylation · Minoxidil · Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase
[Abstract]

3 Collagen structure regulates fibril mineralization in osteogenesis as revealed by cross-link patterns in calcifying callus
article 2000    
Author: Wassen, M.H.M. · Lammens, J. · Tekoppele, J.M. · Sakkers, R.J.B. · Liu, Z. · Verbout, A.J. · Bank, R.A.
Keywords: Biology · Biomedical Research · Callus · Collagen · Cross-links · Lysyl hydroxylation · Mineralization · Calcium ion · Collagen fibril · Deoxypyridinoline · Hydroxylysine · Pyridinoline · Animal cell · Calcification · Collagen degradation · Collagen synthesis · Controlled study · Geometry · Hydroxylation · Mineralization · Nonhuman · Osteolysis · Protein cross linking · Amino Acids · Animals · Bone Remodeling · Bony Callus · Calcification, Physiologic · Calcium · Collagen · Dogs · Fractures, Bone · Hydroxylysine · Lysine · Osteogenesis · Protein Denaturation · Tibia · Time Factors
[Abstract]

4 Bone turnover, joint damage and bone mineral density in early rheumatoid arthritis treated with combination therapy including high-dose prednisolone
article 2001    
Author: Verhoeven, A.C. · Boers, M. · Koppele, J.M. te · Laan, W.H. van der · Markusse, H.M.Geusens, P. · Linden, S. van der
Keywords: Health Biology · Biomedical Research · Adult · Aged · Amino Acids · Anti-Inflammatory Agents · Anti-Inflammatory Agents, Non-Steroidal · Antirheumatic Agents · Arthritis, Rheumatoid · Bone Density · Bone Remodeling · Collagen · Cross-Linking Reagents · Drug Therapy, Combination · Female · Humans · Joints · Male · Methotrexate · Middle Aged · Postmenopause · Prednisolone · Regression Analysis · Sulfasalazine · Bone mineral density · Collagen crosslinks · Deoxypyridinoline · Early rheumatoid arthritis · Glucocorticoids · Outcomes · Pyridinoline
[Abstract]

5 Serum and urinary biochemical markers for knee and hip-osteoarthritis: a systematic review applying the consensus BIPED criteria
article 2010    
Author: Spil, W.E. van · Groot, J. de · Lems, W.F. · Oostveen, J.C.M. · Lafeber, F.P.J.G.
Keywords: Biology · Biomedical Research · Biochemical markers · Biomarkers · BIPED classification · Osteoarthritis · bone sialoprotein · cartilage oligomeric matrix protein · chondroitin sulfate · collagen type 1 · collagen type 2 · deoxypyridinoline · hyaluronic acid · keratan sulfate · osteocalcin · pentosidine · pyridinoline · risedronic acid · blood analysis · bone metabolism · cartilage degeneration · collagen synthesis · diagnostic value · disease severity · hip osteoarthritis · knee osteoarthritis · prognosis · synovium · systematic review · treatment response · urinalysis
[Abstract]

6 A novel pyrroleninone cross-link from bovine dentine
article 1998    
Author: Kleter, G.A. · Damen, J.J.M. · Kettenes-Bosch, J.J. van den · Bank, R.A. · Koppele, J.M. te · Veraart, J.R. · Cate, J.M. ten
Keywords: Nutrition · Collagen · Cow · Cross-linking amino acid · Dentine · Amino acid · Hydroxylysine · Pyridinoline · Pyridone derivative · Reagent · Cattle · Chemical structure · Cross linking · Dentin · Gel permeation chromatography · Ion exchange chromatography · Nonhuman · Nuclear magnetic resonance spectroscopy · Priority journal · Amino Acids · Animals · Cattle · Chromatography, Ion Exchange · Collagen · Cross-Linking Reagents · Dentin · Electrophoresis, Capillary · Magnetic Resonance Spectroscopy · Mass Spectrometry · Molecular Structure · Pyrroles
[Abstract]

7 Functional adaptation of equine articular cartilage: The formation of regional biochemical characteristics up to age one year
article 2000    
Author: Brama, P.A.J. · Tekoppele, J.M. · Bank, R.A. · Barneveld, A. · Weeren, P.R. van
Keywords: Health Biology · Biomedical Research · Functional adaptation · Horse · Site · 1,9 dimethylmethylene blue · 1,9-dimethylmethylene blue · Amino acid · Bisbenzimide · Drug derivative · Glycosaminoglycan · Hydroxylysine · Hydroxyproline · Methylene blue · Pyridinoline · Water · Age · Animal disease · Articular cartilage · Chemistry · High performance liquid chromatography · Horse · Joint · Newborn · Nonparametric test · Physiology · Age Factors · Amino Acids · Animals · Animals, Newborn · Bisbenzimide · Cartilage, Articular · Chromatography, High Pressure Liquid · Collagen · DNA · Glycosaminoglycans · Horses · Hydroxylysine · Hydroxyproline · Joints · Methylene Blue · Statistics, Nonparametric · Water
[Abstract]

8 Pyridinium cross-links in bone of patients with osteogenesis imperfecta: Evidence of a normal intrafibrillar collagen packing
article 2000    
Author: Bank, R.A. · Tekoppele, J.M. · Janus, G.J.M. · Wassen, M.H.M. · Pruijs, H.E.H. · Sluijs, H.A.H. van der · Sakkers, R.J.B.
Keywords: Biology · Biomedical Research · Bone · Collagen · Cross-link · Hydroxylysine · Osteogenesis imperfecta · collagen · deoxypyridinoline · hydroxylysine · pepsin A · pyridinium derivative · pyridinoline · adolescent · amino acid analysis · article · bone structure · child · clinical article · collagen metabolism · controlled study · cross linking · human · human tissue · hydroxylation · mineralization · osteogenesis imperfecta · triple helix · Adolescent · Adult · Amino Acids · Arginine · Biological Markers · Biopsy · Bone and Bones · Child · Child, Preschool · Collagen · Humans · Hydroxylysine · Infant · Lysine · Osteogenesis Imperfecta · Pepsin A · Pyridinium Compounds · Reference Values
[Abstract]

9 Topographical mapping of biochemical properties of articular cartilage in the equine fetlock joint
article 2000    
Author: Brama, P.A.J. · Tekoppele, J.M. · Bank, R.A. · Karssenberg, D. · Barneveld, A. · Weeren, P.R. van
Keywords: Biology · Biomedical Research · Biochemical · Cartilage · Horse · Mapping · Site · 1,9 dimethylmethylene blue · 1,9-dimethylmethylene blue · amino acid · bisbenzimide · collagen · DNA · drug derivative · fluorescent dye · glycosaminoglycan · hydroxylysine · methylene blue · pyridinoline · water · animal · animal disease · article · articular cartilage · biomechanics · biopsy · chemistry · extracellular matrix · forelimb · high performance liquid chromatography · histology · horse · joint · physiology · Amino Acids · Animals · Biomechanics · Biopsy · Bisbenzimide · Cartilage, Articular · Chromatography, High Pressure Liquid · Collagen · DNA · Extracellular Matrix · Fluorescent Dyes · Forelimb · Glycosaminoglycans · Horses · Hydroxylysine · Joints · Methylene Blue · Water
[Abstract]

10 Tranexamic acid, an inhibitor of plasminogen activation, reduces urinary collagen cross-link excretion in both experimental and rheumatoid arthritis
article 1998    
Author: Ronday, H.K. · TeKoppele, J.M. · Greenwald, R.A. · Moak, S.A. · Roos, J.A.D.M. de · Dijkmans, B.A.C. · Breedveld, F.C. · Verheijen, J.H.
Keywords: Health · Biomedical Research · Collagen cross-links · Plasminogen activation system · Tranexamic acid · Collagen · Deoxypyridinoline · Plasminogen · Pyridinoline · Tranexamic acid · Adjuvant arthritis · Animal experiment · Clinical trial · Controlled study · High performance liquid chromatography · Human · Joint destruction · Male · Nonhuman · Oral drug administration · Priority journal · Rat · Rheumatoid arthritis · Urinary excretion · Amino Acids · Animals · Antifibrinolytic Agents · Arthritis · Arthritis, Rheumatoid · Biological Markers · Collagen · Humans · Male · Rats · Rats, Inbred Lew · Time Factors · Tranexamic Acid
[Abstract]

11 Ageing and zonal variation in post-translational modification of collagen in normal human articular cartilage: The age-related increase in Non-Enzymatic Glycation affects biomechanical properties of cartilage
article 1998    
Author: Bank, R.A. · Bayliss, M.T. · Lafeber, F.P.J.G. · Maroudas, A. · Tekoppele, J.M.
Keywords: Health Biology · Biomedical Research · amino acid · collagen · collagen fibril · deoxypyridinoline · hydroxylysine · pentosidine · pyridinoline · pyridoxine · unclassified drug · adolescent · amino acid analysis · articular cartilage · clinical article · collagen metabolism · controlled study · cross linking · glycation · human tissue · osteoarthritis · preschool child · protein processing · school child · Adult · Aged · Aged, 80 and over · Aging · Arginine · Biomechanics · Cartilage, Articular · Child · Child, Preschool · Collagen · Cross-Linking Reagents · Glycosylation End Products, Advanced · Humans · Hydroxylysine · Infant · Lysine · Middle Aged · Protein Processing, Post-Translational
[Abstract]

12 Collagen-induced arthritis in rhesus monkeys: Evaluation of markers for inflammation and joint degradation
article 1998    
Author: Hart, B.A. 't · Bank, R.A. · Roos, J.A.D.M. de · Brok, H. · Jonker, M. · Theuns, H.M. · Hakimi, J. · Koppele, J.M.Te.
Keywords: Nutrition · Collagen-induced arthritis · Disease markers · Rhesus monkey · C reactive protein · Collagen · Cyclosporin a · Deoxypyridinoline · Pyridinoline · Animal experiment · Animal model · Arthritis · Blood level · Cartilage degeneration · Controlled study · Diagnostic value · Disease activity · Disease course · Disease marker · Disease predisposition · Disease severity · Female · Inflammation · Joint degeneration · Male · Nonhuman · Priority journal · Remission · Rhesus monkey · Urine level · Weight gain · Weight reduction · Amino Acids · Animals · Antirheumatic Agents · Arthritis, Experimental · Biological Markers · C-Reactive Protein · Collagen · Cross-Linking Reagents · Cyclosporine · Female · Joints · Macaca mulatta · Male · Synovial Fluid · Weight Loss
[Abstract]

13 Synthesis of collagen by bovine chondrocytes cultured in alginate; posttranslational modifications and cell-matrix interaction
article 1997    
Author: Beekman, B. · Verzijl, N. · Bank, R.A. · Von Der Mark, K. · TeKoppele, J.M.
Keywords: Biology · Biomedical Research · Alginate beads · Articular chondrocyte · Collagen · Collagen crosslinks · Posttranslational modification · Proteoglycan · 3 aminopropionitrile · alginic acid · collagen · integrin · pyridinoline · animal cell · binding affinity · cartilage cell · cell interaction · cell proliferation · collagen synthesis · nonhuman · priority journal · protein cross linking · protein processing · Alginates · Amino Acid Sequence · Amino Acids · Aminopropionitrile · Animals · Cartilage, Articular · Cattle · Cell Division · Cells, Cultured · Collagen · DNA · Extracellular Matrix · Glucuronic Acid · Glycosylation · Hexuronic Acids · Kinetics · Oligopeptides · Protein Processing, Post-Translational · Proteoglycans · Time Factors · Animalia · Bos taurus · Bovinae
[Abstract]

14 Elevated formation of pyridinoline cross-links by profibrotic cytokines is associated with enhanced lysyl hydroxylase 2b levels
article 2005    
Author: Slot, A.J. van der · Dura, E.A. van · Wit, E.C. de · Groot, J. de · Huizinga, T.W.J. · Bank, R.A. · Zuurmond, A.M.
Keywords: Lysyl hydroxylase 2b · Pyridinoline · TGF-β · Activin A · Protein lysine 6 oxidase · Transforming growth factor beta · Tumor necrosis factor alpha · Controlled study · Cross linking · Human cell · Protein expression · Skin fibroblast · Skin fibrosis · Upregulation · Activins · Amino Acids · Cells, Cultured · Collagen Type I · Cross-Linking Reagents · Cytokines · Fibroblasts · Fibrosis · Gene Expression Regulation, Enzymologic · Humans · Inhibin-beta Subunits · Interleukin-4 · Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase · Protein Isoforms · RNA, Messenger · Skin · Time Factors · Transforming Growth Factor beta · Tumor Necrosis Factor-alpha · Up-Regulation
[Abstract]

15 Alpha 2(I) collagen deficient oim mice have altered biomechanical integrity, collagen content, and collagen crosslinking of their thoracic aorta
article 2005    
Author: Pfeiffer, B.J. · Franklin, C.L. · Hsieh, F.H. · Bank, R.A. · Phillips, C.L.
Keywords: Biomechanics · Crosslinks · Oim · Type I collagen · functional group · hydroxyproline · pyridinoline · animal cell · animal model · animal tissue · artery disease · ascending aorta · biomechanics · blood vessel parameters · controlled study · descending aorta · evaluation · gene mutation · heterozygote · histology · molecule · morphological trait · mouse · mouse strain · nonhuman · osteogenesis imperfecta · priority journal · protein content · protein cross linking · protein deficiency · protein function · staining · thoracic aorta · wild type · Animals · Aorta, Thoracic · Biomechanics · Collagen · Collagen Type I · Mice · Mice, Mutant Strains · Osteogenesis Imperfecta
[Abstract]

16 Short-chain fructo-oligosaccharides improve magnesium absorption in adolescent girls with a low calcium intake
article 2009    
Author: Heuvel, E.G.H.M. van den · Muijs, T. · Brouns, F. · Hendriks, H.F.J.
Keywords: Health · Biomedical Research · Adolescents · Calcium · Dual stable isotope technique · Fructo-oligosaccharides · Magnesium · True absorption · calcium · deoxypyridinoline · fructose oligosaccharide · isotope · magnesium · maltodextrin · parathyroid hormone · placebo · pyridinoline · vitamin D · adolescent · article · bone metabolism · calcium absorption · calcium intake · calcium metabolism · carbohydrate intake · child · clinical trial · controlled clinical trial · controlled study · crossover procedure · double blind procedure · female · human · magnesium metabolism · normal human · osteolysis · parathyroid hormone blood level · priority journal · randomized controlled trial · school child · treatment duration · urine · vitamin blood level · Absorption · Adolescent · Amino Acids · Bone Resorption · Calcium · Child · Cross-Over Studies · Double-Blind Method · Female · Humans · Magnesium · Oligosaccharides · Parathyroid Hormone · Polysaccharides · Vitamin D
[Abstract]

17 Molecular changes in the degenerated goat intervertebral disc
article 2008    
Author: Hoogendoorn, R. · Doulabi, B.Z. · Huang, C.L. · Wuisman, P.I. · Bank, R.A. · Helder, M.N.
Keywords: Biomedical Research · Animal model · Biochemical composition · Disc degeneration · Gene expression · aggrecan · chondroitin ABC lyase · collagen · collagen type 1 · collagen type 2 · collagenase 3 · glycosaminoglycan · hydroxyproline · metalloproteinase · pyridinoline · thrombospondin · scleroprotein · animal experiment · animal model · article · cross linking · disease severity · female · gene expression · gene sequence · goat · intervertebral disk · intervertebral disk degeneration · nonhuman · priority journal · protein motif · animal · comparative study · disease model · gene expression profiling · genetics · lumbar vertebra · metabolism · methodology · pathology · physiology · spine disease · Animals · Collagen · Disease Models, Animal · Extracellular Matrix Proteins · Female · Gene Expression Profiling · Goats · Intervertebral Disk · Lumbar Vertebrae · Spinal Diseases
[Abstract]

18 Biochemical development of subchondral bone from birth until age eleven months and the influence of physical activity
article 2002    
Author: Brama, P.A.J. · TeKoppele, J.M. · Bank, R.A. · Barneveld, A. · Weeren, P.R. van
Keywords: Health Biology · Biomedical Research · Collagen · Development · Exercise · Horse · Subchondral bone · Calcium · Collagen · Deoxypyridinoline · Hydroxylysine · Water · Amino acid · Pyridinoline · Adaptation · Animal experiment · Articular cartilage · Athlete · Birth · Bone development · Bone disease · Bone growth · Career · Chemical composition · Chondropathy · Controlled study · Cross linking · Developmental stage · Horse · Loading test · Muscle exercise · Newborn · Nonhuman · Pasture · Pathogenesis · Phalanx · Physical activity · Provocation test · Puerperium · Surface property · Water content · Animal · Bone · Bone density · Chemistry · Growth, development and aging · Horse disease · Metabolism · Pathology · Physiology · Weight bearing · Animalia · Equidae · Equus caballus · Amino Acids · Animals · Animals, Newborn · Bone and Bones · Bone Density · Bone Development · Calcium · Collagen · Horse Diseases · Horses · Physical Conditioning, Animal · Water · Weight-Bearing
[Abstract]

19 Temporal changes in collagen composition and metabolism during rodent palatogenesis
article 2000    
Author: Mansell, J.P. · Kerrigan, J. · McGill, J. · Bailey, J. · TeKoppele, J. · Sandy, J.R.
Keywords: Biomedical Research · Collagen · Cross-linking · Matrix metalloproteinase · MMP · Palate · TIMP · gelatinase A · pyridinium derivative · pyridinoline · stromelysin · tissue inhibitor of metalloproteinase · tissue inhibitor of metalloproteinase 1 · tissue inhibitor of metalloproteinase 2 · animal experiment · animal tissue · article · calcification · collagen metabolism · collagen synthesis · controlled study · cross linking · embryo · embryo development · enzyme activity · extracellular matrix · fetus · mouse · nonhuman · ossification · palate · priority journal · Animal · Calcification, Physiologic · Collagen · Cross-Linking Reagents · Embryo and Fetal Development · Female · Gelatinase A · Male · Palate · Rats · Rats, Wistar · Stromelysin 1 · Tissue Inhibitor-of Metalloproteinase-2 · Tissue-Inhibitor of Metalloproteinase-1 · Rodentia · Trixis
[Abstract]

20 Lack of effect of doxycycline on disease activity and joint damage in patients with rheumatoid arthritis. A double blind, placebo controlled trial
article 2001    
Author: Laan, W. van der · Molenaar, E. · Ronday, K. · Verheijen, J. · Breedveld, F. · Greenwald, R. · Dijkmans, B. · Tekoppele, J.
Keywords: Health · Biomedical Research · Doxycycline · Pyridinolines · Rheumatoid arthritis · deoxypyridinoline · doxycycline · placebo · pyridinoline · clinical examination · clinical trial · controlled clinical trial · controlled study · crossover procedure · disease activity · double blind procedure · erythrocyte sedimentation rate · foot radiography · hand radiography · joint destruction · joint stiffness · laboratory test · major clinical study · randomized controlled trial · scoring system · Adolescent · Adult · Aged · Aged, 80 and over · Analysis of Variance · Arthritis, Rheumatoid · Chi-Square Distribution · Cross-Over Studies · Dose-Response Relationship, Drug · Double-Blind Method · Doxycycline · Drug Administration Schedule · Female · Follow-Up Studies · Humans · Male · Middle Aged · Pain Measurement · Reference Values · Severity of Illness Index · Treatment Failure · Treatment Outcome
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 23 found. Next | Sort by date