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Showing 1 to 12 of 12 found. | Sort by date

1 Illuminating the detection chain of bacterial bioreporters
article 2004    
Author: Meer, J.R. van der · Tropel, D. · Jaspers, M.
Keywords: Biology · Biotechnology · bacterium · environmental monitoring · gene expression · genetic engineering · genetics · methodology · mutation · protein transport · reporter gene · short survey · signal transduction · Bacteria · Environmental Monitoring · Gene Expression · Genes, Reporter · Genetic Engineering · Mutation · Protein Transport · Signal Transduction · Bacteria (microorganisms)
[Abstract]

2 A high throughput screening system for predicting chemically-induced reproductive organ deformities
article 2015    
Author: Burg, B. van der · Pieterse, B. · Rorije, E. · Lewin, G. · Linden, S.C. van der · Man, H.Y. · Piersma, A.H. · Mangelsdorf, I. · Wolterbeek, A.P.M. · Kroese, E.D. · Vugt-Lussenburg, B.M.A. van
Keywords: Nutrition · High throughput screening · Reproductive organ deformities · Estrogen–androgen reporter gene assay · Mechanistic validation · 2 ethylhexanoic acid · 2 methoxyethanol · 2,4 dextro isopropylamine salt · 2,4 pyrimethamine · Acetylsalicylic acid · Androgen receptor · Benomyl · Bis(trichloromethyl)sulfone · Carbamazepine · Carbendazim · Cellosolve acetate · Cyanazine · Cyproconazole · Di(n hexyl)phthalate · Dibutyltindichloride · Diglyme · Fenachlorazol ethyl · Glycolic acid · Halosulfuron methyl · Mancozeb · Molinate · Pentachlorophenol · Phthalic acid benzyl butyl ester · Prothioconazole · Toxic substance · Triclopyr · Unclassified drug · Animal experiment · Animal model · Controlled study · Estrogen activity · Genital malformation · Nonhuman · Prediction · Rat · Reporter gene · Reproductive toxicity · Toxicity testing · Food and Nutrition · Healthy Living · Life · RAPID - Risk Analysis for Products in Development · ELSS - Earth, Life and Social Sciences
[Abstract]

3 Development of an androgen reporter gene assay (AR-LUX) utilizing a human cell line with an endogenously regulated androgen receptor
article 2001    
Author: Blankvoort, B.M.G. · Groene, E.M. de · Meeteren-Kreikamp, A.P. van · Witkamp, R.F. · Rodenburg, R.J.T. · Aarts, J.M.M.J.G.
Keywords: Nutrition · Aldosterone · Androgen · Androgen receptor · Androstanolone · Bolasterone · Dexamethasone · Epigallocatechin gallate · Estradiol · Forskolin · Luciferase · Progesterone · Retinoic acid · Trenbolone · Vitamin D · Assay · Cancer cell culture · Controlled study · Genetic transcription · Genetic transfection · Human · Human cell · Priority journal · Reliability · Reporter gene · Transcription regulation · Validation process · Aldosterone · Androgens · Breast Neoplasms · Dexamethasone · Down-Regulation · Estradiol · Genes, Regulator · Genes, Reporter · Humans · Luciferases · Metribolone · Receptors, Androgen · Transfection · Tumor Cells, Cultured
[Abstract]

4 Selection of Arabidopsis mutants overexpressing genes driven by the promoter of an auxin-inducible glutathione S-transferase gene
article 1999    
Author: Kop, D.A.M. van der · Schuyer, M. · Pinas, J.E. · Zaal, B.J. van der · Hooykaas, P.J.J.
Keywords: Nutrition · Arabidopsis thaliana · Auxin-responsive gene expression · Developmental mutants · Glutathione S-transferase · GST · Gup mutant · Auxin · Beta glucuronidase · Gene expression · Glutathione transferase · Kanamycin · Reporter gene · Transgenic plant · Arabidopsis · Chromosome Mapping · Crosses, Genetic · DNA, Bacterial · Enzyme Induction · Ethyl Methanesulfonate · Gene Expression Regulation, Plant · Genes, Plant · Glutathione Transferase · Indoleacetic Acids · Mutagenesis · Mutagens · Mutation · Phenotype · Plants, Genetically Modified · Promoter Regions (Genetics) · Recombinant Fusion Proteins · Up-Regulation
[Abstract]

5 Detection of hormonal anabolic compounds in calf urine and unverified growth-promoting preparations : application of the AR-LUX bioassay for screening and determination of androgenic activity
article 2003    
Author: Blankvoort, B.M.G. · Aarts, J.M.M.J.G. · Schilt, R. · Geerdink, P. · Spenkelink, B. · Rodenburg, R.J.T.
Keywords: Biology · Analytical research · Anabolic agent · Androgen · Boldenone · Drug residue · Luciferase · Androgen receptor mediated luciferase expression system · Animal · Animal experiment · Bioassay · Body growth · Cattle · Cell line · Conference paper · Controlled study · Cytotoxicity · Drug determination · Enzyme assay · European Union · Female · Food contamination · Gene expression · Human · Human cell · Liquid liquid extraction · Male · Methodology · Nonhuman · Reporter gene · Tumor cell line · Urine · Urine level · Anabolic Agents · Animals · Biological Assay · Cattle · Cell Line, Tumor · Drug Residues · Female · Food Contamination · Humans · Luciferases
[Abstract]

6 Potency of isothiocyanates to induce luciferase reporter gene expression via the electrophile-responsive element from murine glutathione S-transferase Ya
article 2009    
Author: Vermeulen, M. · Boerboom, A.M.M.J.F. · Blankvoort, B.M.G. · Aarts, J.M.M.J.G. · Rietjens, I.M.C.M. · Bladeren, P.J. van · Vaes, W.H.J.
Keywords: Biology · Analytical research · Antioxidant · Electrophile-responsive element · Isothiocyanate · electrophile · glutathione s transferase Ya · glutathione transferase · isothiocyanic acid derivative · luciferase · phenyl isothiocyanate · sulforaphane · unclassified drug · animal cell · article · cell assay · cell line · chemical structure · concentration response · controlled study · drug potency · enzyme induction · gene expression regulation · gene induction · gene location · mouse · nonhuman · reporter gene · Animals · Cell Line · Cell Survival · Gene Expression Regulation · Genes, Reporter · Glutathione Transferase · Isothiocyanates · Luciferases · Mice · Response Elements · Murinae
[Abstract]

7 A novel screening method for cell wall mutants in Aspergillus niger identifies UDP-galactopyranose mutase as an important protein in fungal cell wall biosynthesis
article 2008    
Author: Damveld, R.A. · Franken, A. · Arentshorst, M. · Punt, P.J. · Klis, F.M. · Hondel, C.A.M.J.J. van den · Ram, A.F.J.
Keywords: Biology · Biotechnology · Acetamide · Alpha glucan synthase · Green fluorescent protein · Histone H2B · Mutase · Nuclear protein · Uridine diphosphate · Uridine diphosphate galactopyranose mutase · Article · Aspergillus niger · Biosynthesis · Cell wall · Controlled study · DNA sequence · Gene deletion · Gene expression · Mutagenesis · Nonhuman · PagsA gene · Priority journal · Reporter gene · Screening test · Temperature sensitive mutant · Aspergillus niger · Cell Wall · Fungal Proteins · Gene Deletion · Intramolecular Transferases · Mutagenesis · Mutation · Recombination, Genetic · Aspergillus niger · Eukaryota · Fungi
[Abstract]

8 Wnt but not BMP signaling is involved in the inhibitory action of sclerostin on BMP-stimulated bone formation
article 2007    
Author: Bezooijen, R.L. van · Svensson, J.P. · Eefting, D. · Visser, A. · Horst, G. van der · Karperien, M. · Quax, P.H.A. · Vrieling, H. · Papapoulos, S.E. · Dijke, P. ten · Löwik, W.G.M.C.
Keywords: Biology · Biomedical Research · BMP · Bone formation · Microarray · Sclerostin · Signal transduction · SOST · Wnt · Bone morphogenetic protein · Dickkopf 1 protein · Glycoprotein · Growth factor · Protein inhibitor · Sclerostin · Wnt protein · Animal cell · Animal experiment · Animal tissue · Bone disease · Bone mass · Cell differentiation · Controlled study · DNA microarray · Electroporation · Embryo · Expression vector · Gastrocnemius muscle · Gene · Gene expression profiling · Gene targeting · Genetic transcription · Human · Human cell · In vivo study · Male · Mouse · Nonhuman · Ossification · Osteoblast · Osteocyte · Osteosclerosis · Protein family · Reporter gene · Signal transduction · SOST gene · Van buchem disease · Animals · Bone Development · Bone Morphogenetic Proteins · Cells, Cultured · Electroporation · Gene Expression Regulation · Genes, Reporter · Genetic Markers · Humans · Mesoderm · Mice · Muscle, Skeletal · Oligonucleotide Array Sequence Analysis · Recombinant Proteins · Signal Transduction · Transfection · Wnt Proteins
[Abstract]

9 Comparison of three different in vitro mutation assays used for the investigation of cytochrome P450-mediated mutagenicity of nitro-polycyclic aromatic hydrocarbons
article 2000    
Author: Kappers, W.A. · Och, F.M.M. van · Groene, E.M. de · Horbach, G.J.
Keywords: Nutrition · Acetyltransferase · Amestest · AminoPAHs · Cytochrome P450 · HPRT · Mutagenicity · NIH/3T3 cells · NitroPAHs · Shuttle vector · V79 cells · Cytochrome P450 · Polycyclic aromatic hydrocarbon · Animal cell · Cell strain 3T3 · Controlled study · Enzyme activity · Gene locus · In vitro study · Mouse · Mutagenicity · Nonhuman · Priority journal · Reaction analysis · Reporter gene · Shuttle vector · 3T3 Cells · Animals · Cell Line · Cell Survival · Cytochrome P-450 Enzyme System · Dose-Response Relationship, Drug · Enzyme Inhibitors · Ethyl Methanesulfonate · Fluorenes · Humans · Hypoxanthine Phosphoribosyltransferase · Ketoconazole · Lac Operon · Mice · Microsomes, Liver · Mutagenicity Tests · Mutagens · Mutation · Polycyclic Hydrocarbons, Aromatic · Pyrenes · Rats · Recombinant Fusion Proteins · Salmonella typhimurium · Theophylline · Animalia · Cricetinae · Cricetulus griseus · Eukaryota · Salmonella typhimurium · Typhimurium
[Abstract]

10 Functions of the CCCH type zinc finger protein OsGZF1 in regulation of the seed storage protein GluB-1 from rice
article 2014    
Author: Chen, Y. · Sun, A. · Wang, M. · Zhu, Z. · Ouwerkerk, P.B.F.
Keywords: Biology · CCCH · GluB-1 · Glutelin · Repressor · Rice · Zinc finger · DNA binding protein · GluB 1 protein, Oryza · GluB-1 protein, Oryza · Gluten · Nitrogen · Vegetable protein · Zinc finger protein · Binding site · Cytology · DNA sequence · Down regulation · Gene expression regulation · Gene library · Genetics · Metabolism · Molecular genetics · Nucleotide sequence · Physiology · Plant seed · Promoter region · Reporter gene · Rice · RNA interference · Transgenic plant · Two hybrid system · Base Sequence · Binding Sites · DNA-Binding Proteins · Down-Regulation · Gene Expression Regulation, Plant · Gene Library · Genes, Reporter · Glutens · Molecular Sequence Data · Nitrogen · Oryza sativa · Plant Proteins · Plants, Genetically Modified · Promoter Regions, Genetic · RNA Interference · Seeds · Sequence Analysis, DNA · Two-Hybrid System Techniques · Zinc Fingers · Healthy for Life · Healthy Living Healthy Living · Life · MSB - Microbiology and Systems Biology · ELSS - Earth, Life and Social Sciences
[Abstract]

11 Newly constructed stable reporter cell lines for mechanistic studies on electrophile-responsive element-mediated gene expression reveal a role for flavonoid planarity
article 2006    
Author: Boerboom, A.M.J.F. · Vermeulen, M. · Woude, H. van der · Bremer, B.I. · Lee-Hilz, Y.Y. · Kampman, E. · Bladeren, P.J. van · Rietjens, I.M.C.M. · Aarts, J.M.M.J.G.
Keywords: Biology · Benzyl isothiocyanate · Fisetin · Glutathione transferase · Kaempferol · Luteolin · Myricetin · Quercetin · Reduced nicotinamide adenine dinucleotide (phosphate) dehydrogenase (quinone) · Taxifolin · Tert butylhydroquinone · Animal cell · Antioxidant activity · Cancer cell culture · Cancer screening · Chemoprophylaxis · Controlled study · Drug potency · Drug structure · Electrophile responsive element mediated gene · Enzyme induction · Gene · Gene activation · Gene expression · Gene induction · Genetic transcription · Human cell · Molecular interaction · Mouse · Nonhuman · Reporter gene · Screening test · Stereospecificity · Structure activity relation · Tandem repeat · Transcription initiation · Validation study · Animals · Base Sequence · Cell Line · DNA Primers · Enzyme Induction · Flavonoids · Gene Expression · Genes, Reporter · Humans · Luciferases · Mice · Plasmids · Structure-Activity Relationship · Transcription, Genetic · Benzyl isothiocyanate · Electrophile-responsive element (EpRE) · Hepa-1c1c7 cells · Stable luciferase reporter cell lines · Transient transfection
[Abstract]

12 A hepatocyte nuclear factor-3 site in the fibrinogen β promoter is important for interleukin 6-induced expression, and its activity is influenced by the adjacent -148C/T polymorphism
article 2005    
Author: Verschuur, M. · Jong, M.de · Felida, L. · Maat, M.P.M.de · Vos, H.L.
Keywords: Biology · Biomedical Research · Adenosinetriphosphate · Biological membranes · Calcium · Disease control · Positive ions · Proteins · RNA · Yeast · Cardiovascular disease · Genetic variation · MRNA level · Plasma fibrinogen levels · Cardiovascular system · CCAAT enhancer binding protein · Hepatocyte nuclear factor 3 · Small interfering RNA · Unclassified drug · Beta fibrinogen · DNA binding protein · FOXA1 protein, human · FOXA2 protein, human · FOXA3 protein, human · Hepatocyte nuclear factor 3alpha · Hepatocyte nuclear factor 3beta · Hepatocyte nuclear factor 3gamma · Messenger RNA · Nuclear protein · Primer DNA · Transcription factor · Binding site · Cardiovascular disease · Controlled study · Cytokine production · DNA polymorphism · Fibrinogen blood level · Gel mobility shift assay · Gene expression · Gene sequence · Genetic variability · Hepatoma cell · Human · Human cell · Inflammation · Mutational analysis · Promoter region · Protein protein interaction · Reporter gene · Risk factor · Transcription regulation · Biosynthesis · Cell nucleus · Chemistry · Dose response · Electrophoresis · Gene vector · Genetic polymorphism · Genetics · Metabolism · Molecular genetics · Mutation · Nucleotide sequence · Protein binding · Protein motif · RNA interference · Transactivation · Tumor cell line · Alleles · Amino Acid Motifs · Base Sequence · Binding Sites · Cell Line, Tumor · Cell Nucleus · DNA Mutational Analysis · DNA Primers · DNA-Binding Proteins · Dose-Response Relationship, Drug · Electrophoresis · Fibrinogen · Genes, Reporter · Genetic Vectors · Hepatocyte Nuclear Factor 3-alpha · Hepatocyte Nuclear Factor 3-beta · Hepatocyte Nuclear Factor 3-gamma · Humans · Inflammation · Interleukin-6 · Luciferases · Molecular Sequence Data · Mutation · Nuclear Proteins · Polymorphism, Genetic · Promoter Regions (Genetics) · Protein Binding · Risk Factors · RNA Interference · RNA, Messenger · RNA, Small Interfering · Trans-Activation (Genetics) · Transcription Factors · Variation (Genetics)
[PDF] [Abstract]

Search results also available in MS Excel format.

Showing 1 to 12 of 12 found. | Sort by date