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Showing 1 to 14 of 14 found. | Sort by date

1 Genetic inflammatory factors predict restenosis after percutaneous coronary interventions
article 2005    
Author: Monraats, P.S. · Pires, N.M.M. · Agema, W.R.P. · Zwinderman, A.H. · Schepers, A. · Maat, M.P.M. de · Doevendans, P.A. · Winter, R.J. de · Tio, R.A. · Waltenberger, J. · Frants, R.R. · Quax, P.H.A. · Vlijmen, B.J.M. van · Atsma, D.E. · Laarse, A. van der · Wall, E.E. van der · Jukema, J.W.
Keywords: Biology · Biomedical Research · Angioplasty · Genetics · Restenosis · Risk factors · alanine · beta 2 adrenergic receptor · glycine · threonine · adult · aged · allele · Cd14 gene · colony stimulating factor 2 gene · controlled study · coronary artery disease · disease predisposition · eotaxin gene · female · gene identification · genetic polymorphism · genetic risk · haplotype · heart muscle revascularization · human · major clinical study · male · percutaneous coronary intervention · probability · prospective study · restenosis · risk assessment · risk factor · Amino Acid Substitution · Angioplasty, Transluminal, Percutaneous Coronary · Coronary Restenosis · Humans · Inflammation · Polymorphism, Single Nucleotide · Prospective Studies · Treatment Outcome
[Abstract]

2 Drug-eluting stents studies in mice: Do we need atherosclerosis to study restenosis?
article 2006    
Author: Pires, N.M.M. · Jukema, J.W. · Daemen, M.J.A.P. · Quax, P.H.A.
Keywords: Health · Biomedical Research · (Histo)Pathology · Animal models · Atherosclerosis · Drug-eluting stents · Restenosis · 7 hexanoyltaxol · Dactinomycin · Dexamethasone · Everolimus · Paclitaxel · Paclitaxel derivative · Qp 2 · Rapamycin · Tacrolimus · Thalidomide · Unclassified drug · Artery intima proliferation · Atherosclerosis · Blood pressure variability · Clinical trial · Coronary stent · Cost effectiveness analysis · Disease exacerbation · Disease model · Drug efficacy · Drug eluting stent · Drug release · Drug safety · Evaluation · Healing impairment · Hypersensitivity reaction · In-stent restenosis · Mouse strain · Nonhuman · Pain · Rash · Respiratory tract disease · Restenosis · Side effect · Thrombosis · Animals · Atherosclerosis · Coronary Restenosis · Disease Models, Animal · Drug Delivery Systems · Drug Evaluation, Preclinical · Humans · Mice · Paclitaxel · Sirolimus · Stents
[Abstract]

3 The influence of established genetic variation in the haemostatic system on clinical restenosis after percutaneous coronary interventions
article 2007    
Author: Pons, D. · Monraats, P.S. · Maat, M.P.M. de · Pires, N.M.M. · Quax, P.H.A. · Vlijmen, B.J.M. van · Rosendaal, F.R. · Zwinderman, A.H. · Doevendans, P.A.F.M. · Waltenberger, J. · Winter, R.J. de · Tio, R.A. · Frants, R.R. · Laarse, A. van der · Wall, E.E. van der · Jukema, J.W.
Keywords: Biology · Biomedical Research · Coagulation factors · Polymorphisms · Restenosis · Aged · Angioplasty, Transluminal, Percutaneous Coronary · Coronary Restenosis · Coronary Stenosis · Diabetes Complications · Factor V · Factor VII · Female · Follow-Up Studies · Genetic Predisposition to Disease · Hemostasis · Heterozygote · Homozygote · Humans · Male · Middle Aged · Netherlands · Phenotype · Plasminogen Activator Inhibitor 1 · Polymorphism, Genetic · Proportional Hazards Models · Prospective Studies · Prothrombin · Research Design · Risk Assessment · Risk Factors · Smoking · Time Factors · Treatment Outcome
[PDF] [Abstract]

4 Dexamethasone-eluting stents for the prevention of in-stent restenosis: Evidence for a differential effect in insulin-dependent and non-insulin-dependent diabetic patients
article 2008    
Author: Hoeven, B.L. van der · Pires, N.M.M. · Warda, H.M. · Putter, H. · Quax, P.H.A. · Schalij, M.J. · Jukema, J.W.
Keywords: Health · Dexamethasone · Diabetes mellitus · Restenosis · dexamethasone · adult · aged · angiography · article · clinical article · drug eluting stent · dyslipidemia · female · follow up · heart infarction · human · hypertension · insulin dependent diabetes mellitus · male · non insulin dependent diabetes mellitus · priority journal · restenosis · revascularization · smoking · survival · Adolescent · Adult · Aged · Angioplasty, Transluminal, Percutaneous Coronary · Cohort Studies · Coronary Angiography · Coronary Restenosis · Coronary Stenosis · Dexamethasone · Diabetes Mellitus, Type 1 · Diabetes Mellitus, Type 2 · Diabetic Angiopathies · Drug-Eluting Stents · Female · Follow-Up Studies · Humans · Male · Middle Aged · Probability · Risk Assessment · Survival Rate · Treatment Outcome · Ultrasonography, Interventional
[Abstract]

5 Current PTCA practice and clinical outcomes in the Netherlands: The real world in the pre-drug-eluting stent era
article 2004    
Author: Agema, W.R.P. · Monraats, P.S. · Zwinderman, A.H. · Winter, R.J. de · Tio, R.A. · Doevendans, P.A.F.M. · Waltenberger, J. · Maat, M.P.M. de · Frants, R.R. · Atsma, D.E. · Laarse, A. van der · Wall, E.E. van der · Jukema, J.W.
Keywords: Biology · Biomedical Research · Percutaneous transluminal coronary angioplasty · Restenosis · acetylsalicylic acid · clopidogrel · fibrinogen receptor antagonist · ticlopidine · acute heart infarction · adult · aged · clinical trial · coronary artery bypass graft · diabetes mellitus · drug eluting stent · follow up · heart death · heart disease · hypertension · interventional cardiovascular procedure · major clinical study · multicenter study · peripheral vascular disease · practice guideline · restenosis · revascularization · risk factor · stable angina pectoris · transluminal coronary angioplasty · treatment outcome · Angioplasty, Transluminal, Percutaneous Coronary · Coronary Restenosis · Drug Implants · Female · Follow-Up Studies · Humans · Male · Middle Aged · Myocardial Revascularization · Netherlands · Professional Practice · Prospective Studies · Risk Factors · Stents · Treatment Outcome
[Abstract]

6 The effect of interleukin-10 knock-out and overexpression on neointima formation in hypercholesterolemic APOE*3-Leiden mice
article 2007    
Author: Eefting, D. · Schepers, A. · Vries, M.R. de · Pires, N.M.M. · Grimbergen, J.M. · Lagerweij, T. · Nagelkerken, L.M. · Monraats, P.S. · Jukema, J.W. · Bockel, J.H. van · Quax, P.H.A.
Keywords: Biology · Biomedical Research · Animal models · Cytokines · Electroporation · Gene therapy · In vivo delivery · Inflammation · Restenosis · cytokine · interleukin 10 · animal experiment · animal model · article · cholesterol blood level · controlled study · electroporation · experimental model · gene overexpression · gene transfer · hypercholesterolemia · immunohistochemistry · inflammation · intima · male · morphometrics · mouse · nonhuman · priority journal · restenosis · reverse transcription polymerase chain reaction · RNA isolation · Animals · Disease Models, Animal · Hypercholesterolemia · Interleukin-10 · Mice · Mice, Knockout · Tunica Intima · Vascular Diseases
[Abstract]

7 Epigenetic histone acetylation modifiers in vascular remodelling : New targets for therapy in cardiovascular disease
article 2009    
Author: Pons, D. · Vries, F.R. de · Elsen, P.J. van den · Heijmans, B.T. · Quax, P.H.A. · Jukema, J.W.
Keywords: Biology · Biomedical Research · Atherosclerosis · Epigenetics · Histone acetylation · Restenosis · aroylpyrrolylhydroxypropenamide · azelaic acid · azelaic bishydroxamic acid · Carboxycinnamic acid bishydroxamide · Depsipeptide · Hydroxamic acid derivative · Oxamflatin · Panobinostat · Pivaloyloxymethyl butyrate · Pyroxamide · Romidepsin · Suberoyl bishydroxamic acid · Trichostatin A · Tubacin · Drug · Cardiovascular disease · Chromatin structure · Deacetylation · Disease course · Gene expression regulation · Genetic epidemiology · Genetic heterogeneity · Genotype environment interaction · Heart ventricle remodeling · Inflammation · Molecular dynamics · Nonhuman · Pathogenesis · Promoter region · Protein expression · Restenosis · Smooth muscle fiber · Structure activity relation · Vascular smooth muscle · Acetylation · Cell Proliferation · Epigenesis, Genetic · Extracellular Matrix · Histone Acetyltransferases · Histone Deacetylases · Humans
[Abstract]

8 Inhibition of neointima formation by local delivery of estrogen receptor alpha and beta specific agonists
article 2007    
Author: Krom, Y.D. · Pires, N.M.M. · Jukema, J.W. · Vries, M.R. de · Frants, R.R. · Havekes, L.M. · Dijk, K.W. van · Quax, P.H.A.
Keywords: Biology · Biomedical Research · Animal model · Estrogens · Hormones · Receptors · Restenosis · 2,3 bis(4 hydroxyphenyl)propionitrile · 4,4',4'' (4 propyl [1h] pyrazole 1,3,5 triyl)tris phenol · antiestrogen · estradiol · estrogen receptor alpha · estrogen receptor beta · methylpiperidinopyrazole · phenol derivative · propionitrile · pyrazole derivative · agonist · animal cell · animal model · article · controlled study · cuff · dose response · drug eluting stent · femoral artery · hormone inhibition · intima · male · mouse · nonhuman · priority journal · restenosis · sensitivity and specificity · Animals · Cell Proliferation · Drug Implants · Estradiol · Estrogen Receptor alpha · Estrogen Receptor beta · Femoral Artery · Immunohistochemistry · Male · Mice · Mice, Inbred C57BL · Models, Animal · Nitriles · Propionates · Pyrazoles · Reverse Transcriptase Polymerase Chain Reaction · Tunica Intima
[Abstract]

9 Interleukin 10: A new risk marker for the development of restenosis after percutaneous coronary intervention
article 2007    
Author: Monraats, P.S. · Kurreeman, F.A.S. · Pons, D. · Sewgobind, V.D.K.D. · Vries, F.R. de · Zwinderman, A.H. · Maat, M.P.M. de · Doevendans, P.A. · Winter, R.J. de · Tio, R.A. · Waltenberger, J. · Huizinga, T.W.J. · Eefting, D. · Quax, P.H.A. · Frants, R.R. · Laarse, A. van der · Wall, E.E. van der · Jukema, J.W.
Keywords: Health · Biomedical Research · alanine · clopidogrel · cysteine · glycine · interleukin 10 · ticlopidine · adult · aged · article · cardiovascular risk · confidence interval · controlled study · coronary artery bypass graft · disease marker · DNA flanking region · DNA microarray · drug eluting stent · female · gene linkage disequilibrium · gene locus · genetic association · genetic polymorphism · genetic predisposition · genetic risk · genetic variability · genotype · heart infarction · human · hypothesis · in-stent restenosis · major clinical study · male · pathogenesis · percutaneous coronary intervention · priority journal · risk factor · 3' Untranslated Regions · Aged · Angioplasty, Transluminal, Percutaneous Coronary · Coronary Restenosis · Female · Genetic Predisposition to Disease · Genotype · Humans · Inflammation · Interleukin-10 · Male · Middle Aged · Polymorphism, Genetic · Promoter Regions (Genetics) · Prospective Studies · Risk Factors · Treatment Outcome
[Abstract]

10 Local perivascular delivery of anti-restenotic agents from a drug-eluting poly(ε-caprolactone) stent cuff
article 2005    
Author: Pires, N.M.M. · Hoeven, B.L. van der · Vries, M.R. de · Havekes, L.M. · Vlijmen, B.J. van · Hennink, W.E. · Quax, P.H.A. · Jukema, J.W.
Keywords: Biology · Biomedical Research · Animal model · Controlled drug release · Drug-eluting stents · Local delivery · Poly(ε-caprolactone) · Restenosis · Cardiology · Cell culture · Mathematical models · Muscle · Anti-restenotic agents · Contralateral femoral arteries · Drug-eluting stents (DES) · Interventional cardiology · Controlled drug delivery · Actin · Macrogol 300 · Macrogol derivative · Paclitaxel · Polycaprolactone · Polymer · Rapamycin · Unclassified drug · Animal experiment · Animal tissue · Artery intima proliferation · controlled study · Dose response · Drug delivery system · Drug formulation · Femoral artery · In vivo study · In-stent restenosis · Mouse · Nonhuman · Reproducibility · Smooth muscle fiber · Sustained drug release · Animals · Blood Vessel Prosthesis · Coated Materials, Biocompatible · Diffusion · Drug Carriers · Drug Implants · Femoral Artery · Graft Occlusion, Vascular · Immunosuppressive Agents · Male · Materials Testing · Mice · Mice, Inbred C57BL · Paclitaxel · Polyesters · Sirolimus · Stents · Animalia
[Abstract]

11 Tumor necrosis factor-α plays an important role in restenosis development
article 2005    
Author: Monraats, P.S. · Pires, N.M.M. · Schepers, A. · Agema, W.R.P. · Boesten, L.S.M. · Vries, M.R. de · Zwinderman, A.H. · Maat, M.P.M. de · Doevendans, P.A.F.M. · Winter, R.J. de · Tio, R.A. · Waltenberger, J. · Hart, L.M. 't · Frants, R.R. · Quax, P.H.A. · Vlijmen, B.J.M. van · Havekes, L.M. · Laarse, A. van der · Wall, E.E. van der · Jukema, J.W.
Keywords: Biology Health · Biomedical Research · Haplotype · TNFα · Transgenic mice · Apolipoprotein E3 · Messenger RNA · Thalidomide · Tumor necrosis factor alpha · Adult · Aged · Angiography · Animal experiment · Animal model · Clinical practice · Disease marker · Drug delivery system · Genetic polymorphism · Heredity · Knockout mouse · Nonhuman · Percutaneous coronary intervention · Restenosis · Risk assessment · Screening · Aged · Alleles · Angina Pectoris · Angiography · Angioplasty, Transluminal, Percutaneous Coronary · Animals · Constriction, Pathologic · Coronary Angiography · Coronary Disease · Coronary Restenosis · Disease Models, Animal · Female · Femoral Artery · Gene Expression Regulation, Neoplastic · Genetic Predisposition to Disease · Genotype · Haplotypes · Humans · Inflammation · Ischemia · Linkage Disequilibrium · Male · Mice · Mice, Knockout · Mice, Transgenic · Middle Aged · Multivariate Analysis · Odds Ratio · Polymorphism, Genetic · Regression Analysis · Reverse Transcriptase Polymerase Chain Reaction · Risk Factors · RNA, Messenger · Thalidomide · Treatment Outcome · Tumor Necrosis Factor-alpha · Up-Regulation · Animalia · Mus musculus
[Abstract]

12 Activation of nuclear receptor Nur77 by 6-mercaptopurine protects against neointima formation
article 2007    
Author: Pires, N.M.M. · Pols, T.W.H. · Vries, M.R. de · Tiel, C.M.van · Bonta, P.I. · Vos, M. · Arkenbout, E.K. · Pannekoek, H. · Jukema, J.W. · Quax, P.H.A. · Vries, C.J.M. de
Keywords: Biology · Biomedical Research · Muscle, smooth · Receptors, cytoplasmic and nuclear · Restenosis · Stents · Transcription factors · cyclin dependent kinase inhibitor 1B · cycline · mercaptopurine · messenger RNA · nuclear receptor Nur77 · polycaprolactone · small interfering RNA · staurosporine · thymidine · tritium · animal experiment · animal model · animal tissue · antiangiogenic activity · antigen expression · apoptosis · artery intima proliferation · article · blood vessel injury · blood vessel wall · cell culture · cell cycle arrest · cell proliferation · controlled study · DNA synthesis · drug delivery system · drug dose comparison · drug effect · elution · experimental model · femoral artery · gene overexpression · human · human cell · hypothesis · in-stent restenosis · inflammation · intima · local therapy · male · mouse · nonhuman · observation · priority journal · protein expression · receptor down regulation · receptor upregulation · smooth muscle fiber · sustained drug release · transgenic mouse · vascular smooth muscle · wild type · 6-Mercaptopurine · Animals · Antimetabolites, Antineoplastic · Apoptosis · Cell Division · Cells, Cultured · Coronary Restenosis · Disease Models, Animal · DNA-Binding Proteins · Drug Implants · Femoral Artery · Humans · Male · Mice · Mice, Inbred Strains · Mice, Transgenic · Muscle, Smooth, Vascular · Receptors, Cytoplasmic and Nuclear · Receptors, Steroid · RNA, Messenger · RNA, Small Interfering · Transcription Factors · Tunica Intima · Umbilical Arteries
[PDF] [Abstract]

13 Sirolimus and paclitaxel provoke different vascular pathological responses after local delivery in a murine model for restenosis on underlying atherosclerotic arteries
article 2007    
Author: Pires, N.M.M. · Eefting, D. · Vries, M.R.de · Quax, P.H.A. · Jukema, J.W.
Keywords: Biology · Biomedical Research · collagen · Fas antigen · gelatinase B · messenger RNA · paclitaxel · protein Bax · protein bcl 2 · rapamycin · tissue inhibitor of metalloproteinase 1 · animal experiment · animal model · animal tissue · apoptosis · article · atherosclerosis · blood vessel reactivity · cell disruption · controlled study · dose response · drug eluting stent · drug megadose · femoral artery · histopathology · hypercholesterolemia · male · mouse · nonhuman · priority journal · protein expression · real time polymerase chain reaction · restenosis · upregulation · Actins · Animals · Apoptosis · Atherosclerosis · Cell Proliferation · Collagen · Drug Implants · Femoral Artery · Image Interpretation, Computer-Assisted · In Situ Nick-End Labeling · Male · Mice · Mice, Mutant Strains · Models, Animal · Muscle, Smooth, Vascular · Paclitaxel · Recurrence · Reverse Transcriptase Polymerase Chain Reaction · RNA, Messenger · Sirolimus · Stents · Tunica Intima
[Abstract]

14 Prolonged in vivo gene silencing by electroporation-mediated plasmid delivery of small interfering RNA
article 2007    
Author: Eefting, D. · Grimbergen, J.M. · Vries, M.R. de · Weel, V. van · Kaijzel, E.L. · Que, I. · Moon, R.T. · Löwik, C.W. · Bockel, J.H. van · Quax, P.H.A.
Keywords: Biology · Biomedical Research · double stranded RNA · histidine · luciferase · oligonucleotide · plasmid vector · small interfering RNA · toll like receptor 4 · uridine · animal cell · animal experiment · article · bioluminescence · controlled study · electroporation · gastrocnemius muscle · gene expression · gene function · gene repression · gene silencing · human · human cell · immune response · in vivo gene transfer · in vivo study · male · mouse · nonhuman · nonviral gene delivery system · protein expression · restenosis · RNA interference · transgene · treatment planning · tumor · viral gene delivery system · Animals · Cattle · Cell Line, Transformed · Cell Transformation, Viral · Electroporation · Feasibility Studies · Gene Silencing · Genes, Reporter · Humans · Hypoxanthine Phosphoribosyltransferase · Lipopolysaccharides · Luciferases · Luminescent Measurements · Male · Mice · Mice, Inbred Strains · Muscle, Skeletal · NIH 3T3 Cells · Plasmids · RNA Interference · RNA, Messenger · RNA, Small Interfering · Time Factors · Toll-Like Receptor 4 · Murinae
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 14 of 14 found. | Sort by date