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1 Apolipoprotein CI inhibits scavenger receptor BI and increases plasma HDL levels in vivo
article 2008    
Author: Haan, W. de · Out, R. · Berbée, J.F.P. · Hoogt, C.C. van der · Dijk, K.W.v. · Berkel, T.J.C. van · Romijn, J.A. · Wouter Jukema, J. · Havekes, L.M. · Rensen, P.C.N.
Keywords: Health · Physiological Sciences · High density lipoprotein · Oxidized LDL · SR-BI · Transgenic mice · cholesterol ester · high density lipoprotein cholesterol · scavenger receptor BI · Adenovirus · animal cell · cholesterol metabolism · dose response · in vivo study · liver cell · mouse · nonhuman · particle size · protein expression · Adenoviridae · Animals · Apolipoprotein C-I · Cholesterol, HDL · Gene Transfer Techniques · Hepatocytes · Humans · Mice · Mice, Knockout · Scavenger Receptors, Class B · Adenoviridae · Murinae · Mus · Mus musculus
[Abstract]

2 Scavenger Receptor BI Plays a Role in Facilitating Chylomicron Metabolism
article 2004    
Author: Out, R. · Kruijt, J.K. · Rensen, P.C.N. · Hildebrand, R.B. · Vos, P. de · Eck, M. van · Berkel, T.J.C. van
Keywords: Biology · Biomedical Research · Emulsions · Metabolism · Proteins · Cell association · High density lipoproteins (HDL) · Biochemistry · Chylomicron · High density lipoprotein cholesterol · Low density lipoprotein receptor · Low density lipoprotein receptor related protein · Oxidized low density lipoprotein · Scavenger receptor · Scavenger receptor BI · Triacylglycerol · Unclassified drug · Animal cell · Animal experiment · Cholesterol transport · Controlled study · Emulsion · Internalization · Lipid metabolism · Liver cell · Molecular recognition · Mouse · Nonhuman · Postprandial state · Animals · Antigens, CD36 · Binding Sites · Biological Transport · Chylomicron Remnants · Chylomicrons · Emulsions · Hepatocytes · Mice · Mice, Mutant Strains · Receptors, Immunologic · Receptors, Scavenger · Scavenger Receptors, Class B · Tissue Distribution · Triglycerides · Animalia
[PDF] [Abstract]

3 The hepatic uptake of VLDL in lrp-ldlr-/-vldlr-/- mice is regulated by LPL activity and involves proteoglycans and SR-BI
article 2008    
Author: Hu, L. · Hoogt, C.C. van der · Espirito Santo, S.M.S. · Out, R. · Kypreos, K.E. · Vlijmen, B.J.M. van · Berkel, T.J.C. van · Romijn, J.A. · Havekes, L.M. · Dijk, K.W. van · Rensen, P.C.N.
Keywords: Biology · Apolipoprotein · Denovirus-mediated gene transfer · Lipoprotein lipase · Low density lipoprotein receptor · Low density lipoprotein receptor-related protein · Transgenic mice · Triglyceride-rich emulsion particles · Very low density lipoprotein receptor · apolipoprotein E · cell surface protein · cholesterol · lipoprotein lipase · low density lipoprotein receptor · low density lipoprotein receptor related protein · proteoglycan · proteoheparan sulfate · scavenger receptor BI · triacylglycerol · very low density lipoprotein · very low density lipoprotein receptor · CD36 antigen · ligand · very low density lipoprotein cholesterol · Adenovirus · animal cell · animal experiment · animal tissue · article · cell isolation · cell surface · controlled study · enzyme activity · in vitro study · in vivo study · internalization · lipid analysis · liver cell · male · mouse · nonhuman · priority journal · protein expression · regulatory mechanism · animal · blood · emulsion · genetics · liver · metabolism · mouse mutant · Animals · Antigens, CD36 · Cholesterol, VLDL · Emulsions · LDL-Receptor Related Proteins · Ligands · Lipoprotein Lipase · Liver · Male · Mice · Mice, Knockout · Proteoglycans · Receptors, LDL · Healthy for Life · Healthy Living
[Abstract]

4 Atorvastatin increases HDL cholesterol by reducing CETP expression in cholesterol-fed APOE*3-Leiden.CETP mice
article 2008    
Author: Haan, W. de · Hoogt, C.C. van der · Westerterp, M. · Hoekstra, M. · Dallinga-Thie, G.M. · Princen, H.M.G. · Romijn, J.A. · Jukema, J.W. · Havekes, L.M. · Rensen, P.C.N.
Keywords: Health · CETP · High-density lipoprotein · HMGCoA reductase · Statin · Transgenic mice · ABC transporter A1 · apolipoprotein A1 · apolipoprotein E3 · atorvastatin · cholesterol ester transfer protein · high density lipoprotein · high density lipoprotein cholesterol · messenger RNA · phospholipid transfer protein · scavenger receptor BI · very low density lipoprotein · very low density lipoprotein cholesterol · animal experiment · animal model · article · cholesterol blood level · cholesterol diet · controlled study · drug effect · gene expression · hypercholesterolemia · lipoprotein blood level · lipoprotein metabolism · male · mouse · nonhuman · priority journal · protein expression · transgenic mouse · Animals · Apolipoprotein E3 · Cholesterol Ester Transfer Proteins · Cholesterol, Dietary · Cholesterol, HDL · Cholesterol, VLDL · Dose-Response Relationship, Drug · Female · Gene Expression · Heptanoic Acids · Humans · Hydroxymethylglutaryl-CoA Reductase Inhibitors · Hypercholesterolemia · Liver · Male · Mice · Mice, Inbred C57BL · Mice, Transgenic · Pyrroles · RNA, Messenger
[Abstract]

5 Innovative pharmaceutical interventions in cardiovascular disease: Focusing on the contribution of non-HDL-C/LDL-C-lowering versus HDL-C-raisingA systematic review and meta-analysis of relevant preclinical studies and clinical trials
article 2015    
Author: Kühnast, S. · Fiocco, M. · Hoorn, J.W.A. van der · Princen, H.M.G. · Jukema, J.W.
Keywords: Biology · 3Leiden.CETP mice · ABCA1 degradation inhibitors · APOE · Apolipoprotein A-I inducer · Apolipoprotein A-I Milano · Apolipoprotein A-I mimetic · Atherosclerosis · Cardiovascular disease · CETP inhibition · Clinical outcome · Clinical trials · Delipidated HDL · Fibrates · Glitazones · Hamster · HDL-cholesterol · LCAT · LDL-cholesterol · Mouse · Myocardial infarction · Niacin · Non-HDL-cholesterol · PPAR agonists · Rabbit · Reconstituted HDL · SR-BI inhibitor · Agents affecting lipid metabolism · ATP binding cassette A1 degradation inhibitor · Cardiovascular agent · Cholesterol ester transfer protein · Cholesterol ester transfer protein inhibitor · Dalcetrapib · Fibric acid derivative · Glitazar derivative · Glitazone derivative · High density lipoprotein cholesterol · Liver X receptor agonist · Low density lipoprotein cholesterol · Nicotinic acid · Peptide derivative · Peroxisome proliferator activated receptor agonist · Placebo · Receptor blocking agent · Scavenger receptor BI inhibitor · Unclassified drug · Adverse outcome · Cardiovascular risk · Cholesterol blood level · Clinical trial (topic) · Disease association · Drug effect · Drug targeting · Heart infarction · Human · Meta analysis · Mortality · Nonhuman · Protein expression · Randomized controlled trial (topic) · Risk management · Risk reduction · Systematic review · Treatment response · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · ELSS - Earth, Life and Social Sciences
[Abstract]

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