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1 Legume Protein Consumption and the Prevalence of Legume Sensitization
article 2018    
Author: Smits, M. · Le, T.M. · Welsing, P. · Houben, G. · Knulst, A. · Verhoeckx, K.
Keywords: Nutrition · Consumption · Food allergy · Food hypersensitivity · Legumes · Peanut · Prediction · Prevalence · Sensitization
[PDF] [Abstract]

2 Unraveling toxicological mechanisms and predicting toxicity classes with gene dysregulation networks
article 2013    
Author: Pronk, T.E. · Someren, P. van · Stierum, R.H. · Ezendam, J. · Pennings, J.L.A.
Keywords: Toxicology · Biomarkers · Classification · Network · Regulation · Skin sensitization · Toxicogenomics · Biomedical Innovation · Healthy Living · Life · MSB - Microbiology and Systems Biology · EELS - Earth, Environmental and Life Sciences
[Abstract]

3 Skin sensitisation and epidermal disposition: The relevance of epidermal disposition for sensitisation hazard identification and risk assessment: The report and recommendations of ECVAM workshop 59a
article 2007    
Author: Basketter, D. · Pease, C. · Kasting, G. · Kimber, I. · Casati, S. · Cronin, M. · Diembeck, W. · Gerberick, F. · Hadgraft, J. · Hartung, T. · Marty, J.P. · Nikolaidis, E. · Patlewicz, G. · Roberts, D. · Roggen, E. · Rovida, C. · Sandt, J. van de
Keywords: Food and Chemical Risk Analysis · cosmetic · analytic method · clearance · conference paper · environmental exposure · epidermis cell · gap junction · hazard assessment · immunity · mathematical computing · priority journal · protein binding · risk assessment · sensitization · skin sensitization · steady state · theoretical model · Allergens · Animal Testing Alternatives · Animals · Cells, Cultured · Guidelines · Humans · Risk Assessment · Skin · Skin Absorption · Skin Tests · Toxicity Tests

4 CD4+CD25+ T cells regulate the intensity of hypersensitivity responses to peanut, but are not decisive in the induction of oral sensitization
article 2007    
Author: Wijk, F. van · Wehrens, E.J.M. · Nierkens, S. · Boon, L. · Kasran, A. · Pieters, R. · Knippels, L.M.J.
Keywords: Nutrition · Toxicology and Applied Pharmacology · Allergic sensitization · CD25+ regulatory T cells · Oral tolerance · Peanut allergy · CD4+ CD25+ T lymphocyte · sensitization · Administration, Oral · Animals · Cells, Cultured · Cytokines · Female · Immune Tolerance · Immunoglobulin E · Immunoglobulin G · Interleukin-2 Receptor alpha Subunit · Lymphocyte Depletion · Mice · Mice, Inbred C3H · Peanut Hypersensitivity · Plant Extracts · T-Lymphocytes, Regulatory
[Abstract]

5 Continued expression of anti-soy protein antibodies in rats bred on a soy protein-free diet for one generation : the importance of dietary control in oral sensitization research
article 1998    
Author: Knippels, L.M.J. · Penninks, A.H. · Houben, G.F.
Keywords: Nutrition · Brown Norway rat · Food allergy · IgG · Oral · Sensitization · Soy protein-free diet · Allergenicity · Animal experiment · Animal tissue · Antibody production · Controlled study · Diet restriction · Food allergy · Food composition · Milk allergy · Nonhuman · Protein restriction · Sensitization · Animals · Diet · Food Hypersensitivity · Hypersensitivity · Immunoglobulin G · Mouth Mucosa · Rats · Rats, Inbred BN · Soybean Proteins
[Abstract]

6 Wheat allergen exposure and the prevalence of work-related sensitization and allergy in bakery workers
article 2008    
Author: Jacobs, J.H. · Meijster, T. · Meijer, E. · Suarthana, E. · Heederik, D.
Keywords: Health · Food and Chemical Risk Analysis · Asthma · Occupational sensitization · Wheat allergen exposure · Work-related respiratory symptoms · Allergen · Adult · Allergic asthma · Controlled study · Female · Health survey · Human · Major clinical study · Male · Occupational exposure · Prevalence · Respiratory tract allergy · Sensitization · Wheat · Wheat allergy · Workplace
[Abstract]

7 Respiratory sensitization : Advances in assessing the risk of respiratory inflammation and irritation
article 2011    
Author: Vandebriel, R. · Callant Cransveld, C. · Crommelin, D. · Diamant, Z. · Glazenburg, B. · Joos, G. · Kuper, F. · Natsch, A. · Nijkamp, F. · Noteborn, H. · Pieters, R. · Roberts, D. · Roggen, E. · Rorije, E. · Seed, M. · Sewald, K. · Heuvel, R. van den · Engelen, J. van · Verstraelen, S. · Loveren, H. van
Keywords: Toxicology · ASAT · Asthma · In vitro · In vivo · Integrated testing · QSAR · Respiratory tract · Rhinitis · Risk assessment · Sensitization · contact allergen · immunoglobulin E · airway remodeling · animal testing alternative · biosafety · bronchus hyperreactivity · cell assay · cellular immunity · dendritic cell · disease predisposition · functional genomics · human · immunopathology · immunoreactivity · in vitro study · mathematical model · mucosal immunity · nonhuman · occupational asthma · predictive value · process development · process model · quantitative analysis · quantitative structure activity relation · reaction analysis · respiratory sensitization · respiratory tract inflammation · respiratory tract injury · review · risk assessment · risk factor · sensitization · Animal Testing Alternatives · Hazardous Substances · Humans · Respiratory Hypersensitivity · Respiratory Tract Diseases · Toxicity Tests · Animalia · Healthy for Life · Healthy Living · Life · QS - Quality & Safety · EELS - Earth, Environmental and Life Sciences
[Abstract]

8 Anchoring molecular mechanisms to the adverse outcome pathway for skin sensitization: Analysis of existing data
article 2014    
Author: Veen, J.W. van der · Soeteman-Hernández, L.G. · Ezendam, J. · Stierum, R. · Kuper, F.C. · Loveren, H. van
Keywords: Biology · Adverse outcome pathway · Allergic contact dermatitis · Human in vitro systems · Mechanisms of toxicity · Molecular map · Skin sensitization · Biomedical Innovation · Healthy Living · Life · MSB - Microbiology and Systems Biology · ELSS - Earth, Life and Social Sciences
[Abstract]

9 Peanut allergy: Sensitization by peanut oil-containing local therapeutics seems unlikely [4]
article 2004    
Author: Peeters, K.A.B.M. · Knulst, A.C. · Rynja, F.J. · Bruijnzeel-Koomen, C.A.F.M. · Koppelman, S.J.
Keywords: Nutrition · Food technology · arachis oil · allergenicity · animal experiment · animal model · comparative study · extraction · immunoblotting · letter · mouse · nonhuman · peanut allergy · priority journal · protein analysis · skin allergy · skin sensitization · Animals · Arachis hypogaea · Dermatologic Agents · Drug Contamination · Humans · Immunization · Peanut Hypersensitivity · Plant Oils

10 The respiratory allergen glutaraldehyde in the local lymph node assay: Sensitization by skin exposure, but not by inhalation
article 2011    
Author: Triel, J.J. van · Bree, B.W.J. van · Roberts, D.W. · Muijser, H. · Duistermaat, E. · Woutersen, R.A. · Kuper, C.F.
Keywords: Nutrition Biology · Toxicology and Applied Pharmacology · Chemical structure · Glutaraldehyde · Inhalation exposure · Local lymph node assay · Respiratory allergy · Sensitization · Healthy Living · Life · QS - Quality & Safety · EELS - Earth, Environmental and Life Sciences
[Abstract]

11 Transfer of a two-tiered keratinocyte assay: IL-18 production by NCTC2544 to determine the skin sensitizing capacity and epidermal equivalent assay to determine sensitizer potency
article 2013    
Author: Teunis, M. · Corsini, E. · Smits, M. · Madsen, C.B. · Eltze, T. · Ezendam, J. · Galbiati, V. · Gremmer, E. · Krul, C.A.M. · Landin, A. · Landsiedel, R. · Pieters, R. · Rasmussen, T.F. · Reinders, J. · Roggen, E. · Spiekstra, S. · Gibbs, S.
Keywords: Biology · Alternatives To Animal Use · Epidermal Equivalent · Keratinocytes · Prevalidation · Ring Study · Skin Sensitization · Tiered Test · Biomedical Innovation · Healthy Living · Healthy Living Life · HL - Healthy for Life RAPID - Risk Analysis for Products in Development · ELSS - Earth, Life and Social SciencesThemalijn
[Abstract]

12 Interlaboratory evaluation of a cow's milk allergy mouse model to assess the allergenicity of hydrolysed cow's milk based infant formulas
article 2013    
Author: Esch, B.C.A.M. van · Bilsen, J.H.M. van · Jeurink, P.V. · Garssen, J. · Penninks, A.H. · Smit, J.J. · Pieters, R.H.H. · Knippels, L.M.J.
Keywords: Biology · Allergenicity · Cow's milk allergy · Hydrolysed infant formulas · Mouse model · Safety · Sensitization · Food and Nutrition · Healthy Living · Life Triskelion BV · QS - Quality & Safety RAPID - Risk Analysis for Products in Development · EELS - Earth, Environmental and Life Sciences TNO Bedrijven
[Abstract]

13 Prevention of work-related airway allergies; summary of the advice from the Health Council of the Netherlands
article 2008    
Author: Rijnkels, J.M. · Smid, T. · Aker, E.C. van den · Burdorf, A. · Wijk, R.G. van · Heederik, D.J.J. · Houben, G.F. · Loveren, H. van · Pal, T.M. · Rooy, F.G.B.G.J. van · Zee, J.S. van der
Keywords: Health · Food and Chemical Risk Analysis · Allergens · Asthma · Environment · Occupational · Prevention · Rhinitis · allergen · human · immune response · immunological procedures · Netherlands · note · occupational allergy · occupational exposure · priority journal · prophylaxis · respiratory tract allergy · sensitization · wheat allergy · workplace
[Abstract]

14 Evaluation of the sensitizing potential of food proteins using two mouse models
article 2016    
Author: Smit, J. · Zeeuw-Brouwer, M.L.D. · Roest, M. van · Jong, G. de · Bilsen, J. van
Keywords: Biology · Allergenic proteins · Allergenicity · Dendritic cells · Food allergy · Mouse models · Sensitization · T cells · Biomedical Innovation · Healthy Living · Life · RAPID - Risk Analysis for Products in Development · ELSS - Earth, Life and Social Sciences
[Abstract]

15 The relevance of a digestibility evaluation in the allergenicity risk assessment of novel proteins. Opinion of a joint initiative of COST action ImpARAS and COST action INFOGEST
article 2019    
Author: Verhoeckx, K. · Bogh, K.L. · Dupont, D. · Egger, L. · Gadermaier, G. · Larre, C. · Mackie, A. · Menard, O. · Adel-Patient, K. · Picariello, G. · Portmann, R. · Smit, J. · Turner, P. · Untersmayr, E. · Epstein, M.M.
Keywords: Allergenicity risk assessment · Food allergy · Food digestion · In vitro protein digestibility tests · Novel proteins · Immunoglobulin E antibody · Intestine enzyme · Protein · Allergenicity · Allergic reaction · Biological activity · Brush border · Digestion · Human · Immune response · Immunogenicity · In vitro study · Risk assessment · Sensitization · Workshop
[PDF] [Abstract]

16 Application of the adverse outcome pathway (AOP) concept to structure the available in vivo and in vitro mechanistic data for allergic sensitization to food proteins
article 2017    
Author: Bilsen, J.H.M. van · Sienkiewicz-Szłapka, E. · Lozano-Ojalvo, D. · Willemsen, L.E.M. · Antunes, C.M. · Molina, E. · Smit, J.J. · Wróblewska, B. · Wichers, H.J. · Knol, E.F. · Ladics, G.S. · Pieters, R.H.H. · Denery-Papini, S. · Vissers, Y.M. · Bavaro, S.L. · Larré, C. · Verhoeckx, K.C.M. · Roggen, E.L.
Keywords: Biology · Adverse outcome pathway · Food allergy · Food proteins · Key event relations · Key events · Mechanistic understanding · Molecular initiating event · Sensitization · Biomedical Innovation · Healthy Living · Life · RAPID - Risk Analysis for Products in Development · ELSS - Earth, Life and Social Sciences
[PDF] [Abstract]

17 Assessment of the allergic potential of food protein extracts and proteins on oral application using the Brown Norway rat model
article 2003    
Author: Knippels, L.M.J. · Penninks, A.H.
Keywords: Toxicology · Toxicology and Applied Pharmacology · Allergic potential · Brown Norway rats · Challenge effects · Egg-white proteins · Food allergy · Food proteins · IgE · Milk proteins · Oral sensitization · Ovalbumin · Passive cutaneous anaphylaxis · adjuvant · egg white · food allergen · immunoglobulin E · immunoglobulin G · ovalbumin · allergenicity · animal experiment · animal model · antibody response · antigen specificity · breathing rate · controlled study · feeding · food allergy · immune response · intestine mucosa permeability · male · milk allergy · nonhuman · peanut allergy · priority journal · protein intake · protein purification · provocation test · rat · rat strain · review · risk assessment · sensitization · symptomatology · systolic blood pressure · Administration, Oral · Allergens · Animals · Disease Models, Animal · Egg Proteins · Food Hypersensitivity · Humans · Immunoglobulin E · Immunoglobulin G · Male · Milk Proteins · Rats · Animalia · Arachis hypogaea · Rattus norvegicus
[Abstract]

18 Respiratory symptoms, sensitization, and exposure-response relationships in spray painters exposed to isocyanates
article 2007    
Author: Pronk, A. · Preller, L. · Raulf-Heimsoth, M. · Jonkers, I.C.L. · Lammers, J.-W. · Wouters, I.M. · Doekes, G. · Wisnewski, A.V. · Heederik, D.
Keywords: Food and Chemical Risk Analysis · Asthma · Isocyanate · Oligomer · Sensitization · Spray painter · hexamethylene diisocyanate · human serum albumin · immunoglobulin E · immunoglobulin G · oligomer · adult · antibody titer · article · asthma · atopy · chest tightness · chronic obstructive lung disease · conjunctivitis · controlled study · coughing · diagnostic kit · dyspnea · enzyme assay · female · human · immunoassay · major clinical study · male · occupational exposure · occupational hazard · office worker · paint industry · painter · prevalence · priority journal · respiratory tract disease · rhinitis · sensitization · wheezing · worker · Adult · Aerosols · Air Pollutants, Occupational · Asthma · Chest Pain · Cyanates · Female · Humans · Immunoglobulin E · Immunoglobulin G · Inhalation Exposure · Male · Middle Aged · Occupational Diseases · Paint · Prevalence · Pulmonary Disease, Chronic Obstructive · Respiration Disorders · Respiratory Hypersensitivity
[Abstract]

19 Comparison of antibody responses to hen's egg and cow's milk proteins in orally sensitized rats and food-allergic patients
article 2000    
Author: Knippels, L.M.J. · Kleij, H.P.M. van der · Koppelman, S.J. · Houben, G.F. · Penninks, A.H. · Felius, A.A.
Keywords: Nutrition · Allergic patients · Brown Norway · Cow's milk · Food allergy · Hen's egg white · IgE · Rat · Sensitization · Egg protein · Egg white · Food allergen · Immunoglobulin E antibody · Immunoglobulin G antibody · Milk protein · Ovalbumin · Allergenicity · Animal experiment · Animal model · Antibody response · Antibody specificity · Antigen recognition · Child · Clinical article · Controlled study · Food allergy · Human · Immunoblotting · Infant · Male · Milk allergy · Nonhuman · Priority journal · Protein intake · Rat · Sensitization · Allergens · Animals · Antibody Specificity · Blotting, Western · Child · Child, Preschool · Dietary Proteins · Electrophoresis, Polyacrylamide Gel · Enzyme-Linked Immunosorbent Assay · Food Hypersensitivity · Humans · Immune System · Immunoglobulin E · Infant · Male · Milk · Milk Hypersensitivity · Milk Proteins · Ovalbumin · Passive Cutaneous Anaphylaxis · Rats · Rats, Inbred BN
[Abstract]

20 Approaches to induce and elicit respiratory allergy: Impact of route and intensity of exposure
article 2003    
Author: Arts, J.H.E. · Kuper, C.F.
Keywords: Toxicology Health · Toxicology and Applied Pharmacology · Airway irritation · Respiratory allergy · Route and intensity of exposure · allergen · irritant agent · allergic reaction · biosafety · conference paper · environmental factor · exposure · heredity · human · inhalation test · nonhuman · prediction · priority journal · respiratory tract allergy · risk assessment · risk management · sensitization · standardization · Administration, Cutaneous · Administration, Inhalation · Allergens · Animals · Dose-Response Relationship, Drug · Predictive Value of Tests · Respiratory System · Animalia
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 55 found. Next | Sort by date