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1 Highly increased levels of active stromelysin in rheumatoid synovial fluid determined by a selective fluorogenic assay
article 1997    
Author: Beekman, B. · El, B. van · Drijfhout, J.W. · Ronday, H.K. · TeKoppele, J.M.
Keywords: Biomedical Research · Fluorogenic substrate · MMP-3 · Rheumatoid arthritis · Stromelysin · Synovial fluid · Stromelysin · Controlled study · Enzyme activity · Enzyme assay · Human tissue · Priority journal · Rheumatoid arthritis · Synovial fluid · Technique · Arthritis, Rheumatoid · Biological Assay · Biological Markers · Fluorescence · Humans · Matrix Metalloproteinase 3
[PDF] [Abstract]

2 Influence of development and joint pathology on stromelysin enzyme activity in equine synovial fluid
article 2000    
Author: Brama, P.A.J. · TeKoppele, J.M. · Beekman, B. · El, B. van · Barneveld, A. · Weeren, P.R. van
Keywords: Biology · Biomedical Research · stromelysin · animal tissue · arthropathy · article · bone development · disease association · enzyme activity · horse · nonhuman · priority journal · protein expression · synovial fluid level · Aging · Animals · Horse Diseases · Horses · Matrix Metalloproteinase 3 · Osteoarthritis · Osteochondritis · Synovial Fluid
[PDF] [Abstract]

3 Gingival tissue and crevicular fluid co-operation in adult periodontitis
article 2006    
Author: Beklen, A. · Tüter, G. · Sorsa, T. · Hanemaaijer, R. · Virtanen, I. · Tervahartiala, T. · Konttinen, Y.T.
Keywords: Health · Collagenase · Gelatinase · Periodontitis · Stromelysin · collagenase · enzyme precursor · gelatinase · gelatinase B · metalloproteinase · neutrophil collagenase · procollagenase · progelatinase · stromelysin · adult · article · cell culture · enzyme activation · enzymology · female · fibroblast · gingiva · gingivitis · human · immunohistochemistry · male · middle aged · pathology · periodontitis · Adult · Cells, Cultured · Collagenases · Enzyme Activation · Enzyme Precursors · Female · Fibroblasts · Gelatinases · Gingiva · Gingival Crevicular Fluid · Humans · Immunohistochemistry · Male · Matrix Metalloproteinase 3 · Matrix Metalloproteinase 8 · Matrix Metalloproteinase 9 · Metalloendopeptidases · Middle Aged · Periodontitis
[Abstract]

4 Temporal changes in collagen composition and metabolism during rodent palatogenesis
article 2000    
Author: Mansell, J.P. · Kerrigan, J. · McGill, J. · Bailey, J. · TeKoppele, J. · Sandy, J.R.
Keywords: Biomedical Research · Collagen · Cross-linking · Matrix metalloproteinase · MMP · Palate · TIMP · gelatinase A · pyridinium derivative · pyridinoline · stromelysin · tissue inhibitor of metalloproteinase · tissue inhibitor of metalloproteinase 1 · tissue inhibitor of metalloproteinase 2 · animal experiment · animal tissue · article · calcification · collagen metabolism · collagen synthesis · controlled study · cross linking · embryo · embryo development · enzyme activity · extracellular matrix · fetus · mouse · nonhuman · ossification · palate · priority journal · Animal · Calcification, Physiologic · Collagen · Cross-Linking Reagents · Embryo and Fetal Development · Female · Gelatinase A · Male · Palate · Rats · Rats, Wistar · Stromelysin 1 · Tissue Inhibitor-of Metalloproteinase-2 · Tissue-Inhibitor of Metalloproteinase-1 · Rodentia · Trixis
[Abstract]

5 Effect of collagen turnover and matrix metalloproteinase activity on healing of venous leg ulcers
article 2008    
Author: Meyer, F.J. · Burnand, K.G. · Abisi, S. · TeKoppele, J.M. · Els, B. van · Smith, A.
Keywords: Health · Collagen type 3 · Interstitial collagenase · Matrix metalloproteinase · Stromelysin · Peptide fragment · Clinical article · Collagen synthesis · controlled study · Enzyme activity · Leg ulcer · Priority journal · Protein analysis · Skin biopsy · Aged · Comparative study · Enzymology · Metabolism · Physiology · Varicosis · Aged · Collagen · Female · Humans · Male · Matrix Metalloproteinases · Peptide Fragments · Procollagen · Skin · Varicose Ulcer · Wound Healing
[Abstract]

6 Regulation of plasminogen activation, matrix metalloproteinases and urokinase-type plasminogen activator-mediated extracellular matrix degradation in human osteosarcoma cell line MG63 by interleukin-1 alpha
article 1995    
Author: Bart, A.C.W. de · Quax, P.H.A. · Löwik, C.W.G.M. · Verheijen, J.H.
Keywords: Health · collagenase · gelatinase · interleukin 1alpha · messenger rna · metalloproteinase · plasminogen · stromelysin · tissue inhibitor of metalloproteinase · urokinase · animal cell · animal tissue · article · bone matrix · bone turnover · calvaria · cattle · controlled study · extracellular matrix · human · human cell · mouse · nonhuman · osteolysis · osteosarcoma · protein degradation · Extracellular Matrix · Human · Interleukin-1 · Metalloendopeptidases · Osteoblasts · Osteosarcoma · Plasminogen Activators · Plasminogen Inactivators · Support, Non-U.S. Gov't · Tumor Cells, Cultured · Urinary Plasminogen Activator
[Abstract]

7 Matrix metalloproteinases in premature coronary atherosclerosis: influence of inhibitors, inflammation, and genetic polymorphisms
article 2007    
Author: Nanni, S. · Melandri, G. · Hanemaaijer, R. · Cervi, V. · Tomasi, L. · Altimari, A. · Lent, N. van · Tricoci, P. · Bacchi, L. · Branzi, A.
Keywords: Health · Biomedical Research · biological marker · gelatinase A · gelatinase B · glucose · haptoglobin · matrix metalloproteinase · stromelysin · tissue inhibitor of metalloproteinase · tissue inhibitor of metalloproteinase 1 · tissue inhibitor of metalloproteinase 2 · adult · article · controlled study · coronary artery atherosclerosis · correlation analysis · enzyme activity · enzyme blood level · exon · genetic polymorphism · glucose blood level · human · human tissue · inflammation · major clinical study · male · metabolic disorder · pathogenesis · priority journal · protein expression · protein localization
[Abstract]

8 Matrix metalloproteinases-3, -8, -9 as markers of disease activity and joint damage progression in early rheumatoid arthritis
article 2003    
Author: Tchetverikov, I. · Lard, L.R. · Groot, J. de · Verzijl, N. · TeKoppele, J.M. · Breedveld, F.C. · Huizinga, T.W.J. · Hanemaaijer, R.
Keywords: Biology · Biomedical Research · gelatinase B · neutrophil collagenase · stromelysin · aged · arthropathy · disease activity · disease course · disease marker · enzyme activity · enzyme blood level · enzyme linked immunosorbent assay · female · human · joint destruction · longitudinal study · major clinical study · male · prediction · rheumatoid arthritis · Adult · alpha-Macroglobulins · Arthritis, Rheumatoid · Biological Markers · C-Reactive Protein · Disease Progression · Female · Humans · Joints · Male · Matrix Metalloproteinase 3 · Matrix Metalloproteinase 9 · Matrix Metalloproteinases · Middle Aged · Prospective Studies · Statistics, Nonparametric
[Abstract]

9 MMP protein and activity levels in synovial fluid from patients with joint injury, inflammatory arthritis, and osteoarthritis
article 2005    
Author: Tchetverikov, I. · Lohmander, L.S. · Verzijl, N. · Huizinga, T.W.J. · TeKoppele, J.M. · Hanemaaijer, R. · Groot, J. de
Keywords: Biomedical Research · alpha 2 macroglobulin · interstitial collagenase · matrix metalloproteinase · prointerstitial collagenase · prostromelysin · stromelysin · tissue inhibitor of metalloproteinase 3 · unclassified drug · arthritis · controlled study · enzyme activation · enzyme activity · enzyme inhibition · human · immunoassay · joint injury · knee · major clinical study · osteoarthritis · priority journal · protein determination · pseudogout · quantitative analysis · synovial fluid level · Acute Disease · Adult · alpha-Macroglobulins · Arthritis · Chondrocalcinosis · Cross-Sectional Studies · Female · Humans · Knee Injuries · Male · Matrix Metalloproteinases · Middle Aged · Osteoarthritis, Knee · Synovial Fluid · Tissue Inhibitor of Metalloproteinase-1
[Abstract]

10 The canine 'groove' model, compared with the ACLT model of osteoarthritis
article 2002    
Author: Marijnissen, A.C.A. · Roermund, P.M. van · TeKoppele, J.M. · Bijlsma, J.W.J. · Lafeber, F.P.J.G.
Keywords: Biology · Biomedical Research · Canine model · Cartilage · Osteoarthritis · Proteoglycans · collagen · collagenase 3 · interstitial collagenase · matrix protein · proteoglycan · stromelysin · animal experiment · animal model · animal tissue · anterior cruciate ligament · article · articular cartilage · biochemistry · cartilage cell · cartilage degeneration · collagen degradation · controlled study · disease model · disease severity · dog · enzyme activity · evaluation · female · femur condyle · histopathology · joint stability · knee · nonhuman · osteoarthritis · priority journal · protein depletion · synovial fluid · synovitis · tissue injury · weight bearing · Animals · Cartilage, Articular · Chondrocytes · Collagen · Collagenases · Dogs · Female · Matrix Metalloproteinase 1 · Matrix Metalloproteinase 13 · Matrix Metalloproteinase 3 · Models, Animal · Osteoarthritis · Proteoglycans · Synovial Fluid · Weight-Bearing
[Abstract]

11 Soluble biomarkers of cartilage and bone metabolism in early proof of concept trials in psoriatic arthritis: Effects of adalimumab versus placebo
article 2010    
Author: Tak, P.P. · Kuijk, A.W.R. van · Groot, J. de · Koeman, R.C. · Sakkee, N. · Baeten, D.L. · Gerlag, D.M.
Keywords: Health · Biomedical Research · adalimumab · amino terminal cross linked telopeptide of type 1 collagen · C propeptide of type 2 collagen · carboxy terminal cross linked telopeptide of type 1 collagen · cartilage oligomeric matrix protein · collagen type 1 · collagen type 2 · osteocalcin · placebo · procollagen · procollagen serum type 1 amino terminal propeptide · stromelysin · unclassified drug · article · bone metabolism · cartilage cell · cartilage metabolism · clinical article · clinical trial · controlled clinical trial · controlled study · correlation analysis · disease marker · drug efficacy · human · ossification · protein analysis · protein blood level · protein degradation · protein function · protein synthesis · psoriatic arthritis · randomized controlled trial · tissue metabolism
[PDF] [Abstract]

12 MMP profile in paired serum and synovial fluid samples of patients with rheumatoid arthritis
article 2004    
Author: Tchetverikov, I. · Ronday, H.K. · El, B. van · Kiers, G.H. · Verzijl, N. · TeKoppele, J.M. · Huizinga, T.W.J. · Groot, J. de · Hanemaaijer, R.
Keywords: alpha 2 macroglobulin · biological marker · gelatinase A · gelatinase B · hydroxyproline · interstitial collagenase · matrix metalloproteinase · neutrophil collagenase · stromelysin · tissue inhibitor of metalloproteinase 1 · aged · circulation · clinical article · collagen degradation · concentration (parameters) · controlled study · correlation analysis · enzyme activity · enzyme assay · enzyme linked immunosorbent assay · female · high performance liquid chromatography · human · male · osteoarthritis · priority journal · rheumatoid arthritis · sampling · serum · statistical significance · synovial fluid · Adult · Aged · alpha-Macroglobulins · Arthritis, Rheumatoid · Case-Control Studies · Collagenases · Enzyme Precursors · Enzyme-Linked Immunosorbent Assay · Female · Humans · Hydroxyproline · Male · Matrix Metalloproteinase 8 · Matrix Metalloproteinase 9 · Matrix Metalloproteinases · Metalloendopeptidases · Middle Aged · Osteoarthritis, Knee · Statistics, Nonparametric · Synovial Fluid · Tissue Inhibitor of Metalloproteinase-1
[Abstract]

13 Effect of the anti-tumor necrosis factor-α antibody infliximab on the ex vivo mucosal matrix metalloproteinase-proteolytic phenotype in inflammatory bowel disease
article 2007    
Author: Meijer, M.J. · Mieremet-Ooms, M.A.C. · Duijn, W. van · Zon, A.M. van der · Hanemaaijer, R. · Verheijen, J.H. · Hogezand, R.A. van · Lamers, C.B.H.W. · Verspaget, H.W.
Keywords: Biomedical Research · Inflammatory bowel disease · Infliximab · Matrix metalloproteinase · Tissue inhibitor of metalloproteinase · Tumor necrosis factor-alpha · azathioprine · cyclosporin · gelatinase A · gelatinase B · infliximab · interstitial collagenase · mesalazine · messenger RNA · pokeweed mitogen · steroid · stromelysin · tissue inhibitor of metalloproteinase 1 · tissue inhibitor of metalloproteinase 2 · tumor necrosis factor alpha antibody · adolescent · adult · aged · article · clinical article · controlled study · Crohn disease · drug effect · enteritis · explant · female · genotype · human · human tissue · intestine mucosa · male · priority journal · protein degradation · protein expression · single nucleotide polymorphism · ulcerative colitis · Adolescent · Adult · Aged · Antibodies, Monoclonal · Colitis, Ulcerative · Crohn Disease · Down-Regulation · Female · Humans · Intestinal Mucosa · Male · Matrix Metalloproteinases · Middle Aged · Phenotype · Polymorphism, Single Nucleotide · Reverse Transcriptase Polymerase Chain Reaction · Tissue Culture Techniques · Tissue Inhibitor of Metalloproteinases · Tumor Necrosis Factor-alpha
[Abstract]

14 Doxycycline therapy for abdominal aneurysm: Improved proteolytic balance through reduced neutrophil content
article 2009    
Author: Abdul-Hussien, H. · Hanemaaijer, R. · Verheijen, J.H. · Bockel, J.H. van · Geelkerken, R.H. · Lindeman, J.H.N.
Keywords: Biology · Biomedical Research · antihypertensive agent · antithrombocytic agent · cystatin C · cysteine proteinase · doxycycline · gelatinase B · hydroxymethylglutaryl coenzyme A reductase inhibitor · messenger RNA · neutrophil collagenase · stromelysin · tissue inhibitor of metalloproteinase 1 · abdominal aorta aneurysm · adult · aged · aorta wall · article · clinical article · clinical trial · controlled clinical trial · controlled study · dose response · drug effect · drug megadose · drug tolerability · enzyme activity · enzyme assay · female · gene expression · human · human tissue · immunohistochemistry · low drug dose · male · neutrophil · polymerase chain reaction · priority journal · protein degradation · quantitative analysis · randomized controlled trial · treatment duration · Western blotting · Aged · Aged, 80 and over · Aorta, Abdominal · Aortic Aneurysm, Abdominal · Cardiovascular Agents · Cystatin C · Cysteine Endopeptidases · Dose-Response Relationship, Drug · Doxycycline · Female · Gene Expression Regulation, Enzymologic · Humans · Male · Matrix Metalloproteinases · Middle Aged · Neutrophil Infiltration · Neutrophils · Prospective Studies · Protease Inhibitors · RNA, Messenger · Time Factors · Tissue Inhibitor of Metalloproteinase-1 · Treatment Outcome · Vascular Surgical Procedures
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 14 of 14 found. | Sort by date