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Showing 1 to 19 of 19 found. | Sort by date

1 Role of transforming growth factor-ß in the preferential induction of T helper cells of type 1 by staphylococcal enterotoxin B
article 1993    
Author: Nagelkerken, L. · Gollob, K.J. · Tielemans, M. · Coffman, R.L.
Keywords: Animal · Antigens, Bacterial · Cells, Cultured · Enterotoxins · Female · Interleukin-4 · Mice · Staphylococcus aureus · Support, Non-U.S. Gov't · T-Lymphocytes, Helper-Inducer · Transforming Growth Factor beta · Helper cell · Lymphocyte differentiation · Mouse · Nonhuman · Spleen cell · T lymphocyte activation · T lymphocyte subpopulation
[Abstract]

2 Elevated formation of pyridinoline cross-links by profibrotic cytokines is associated with enhanced lysyl hydroxylase 2b levels
article 2005    
Author: Slot, A.J. van der · Dura, E.A. van · Wit, E.C. de · Groot, J. de · Huizinga, T.W.J. · Bank, R.A. · Zuurmond, A.M.
Keywords: Lysyl hydroxylase 2b · Pyridinoline · TGF-β · Activin A · Protein lysine 6 oxidase · Transforming growth factor beta · Tumor necrosis factor alpha · Controlled study · Cross linking · Human cell · Protein expression · Skin fibroblast · Skin fibrosis · Upregulation · Activins · Amino Acids · Cells, Cultured · Collagen Type I · Cross-Linking Reagents · Cytokines · Fibroblasts · Fibrosis · Gene Expression Regulation, Enzymologic · Humans · Inhibin-beta Subunits · Interleukin-4 · Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase · Protein Isoforms · RNA, Messenger · Skin · Time Factors · Transforming Growth Factor beta · Tumor Necrosis Factor-alpha · Up-Regulation
[Abstract]

3 Biochemical and functional modulation of the cartilage collagen network by IGF1, TGFβ2 and FGF2
article 2006    
Author: Jenniskens, Y.M. · Koevoet, W. · Bart, A.C.W. de · Weinans, H. · Jahr, H. · Verhaar, J.A.N. · Groot, J. de · Osch, G.J.V.M. van
Keywords: Biology · Biomedical Research · Chondrocyte · Cross-links · Growth factors · Mechanical properties · Proteoglycans · Alginic acid · Collagen fiber · Fibroblast growth factor 2 · Matrix metalloproteinase · Proteoglycan · Pyridinoline · Somatomedin C · Transforming growth factor beta2 · Animal cell · Animal tissue · Cartilage cell · Cartilage matrix · Collagen synthesis · Controlled study · Cow · Culture medium · Enzyme activity · Enzyme analysis · Nonhuman · Permeability · Protein cross linking · Protein determination · Protein function · Protein protein interaction · Rigidity · Aggrecans · Animals · Biomechanics · Cartilage, Articular · Cattle · Cells, Cultured · Chondrocytes · Collagen · Collagen Type II · DNA · Extracellular Matrix · Fibroblast Growth Factor 2 · Forelimb · Gene Expression · Immunohistochemistry · Insulin-Like Growth Factor I · Matrix Metalloproteinases · Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase · Protein-Lysine 6-Oxidase · Proteoglycans · Transforming Growth Factor beta2
[Abstract]

4 Species differences in hepatic peroxisome proliferation, cell replication and transforming growth factor-β1 gene expression in the rat, Syrian hamster and guinea pig
article 2000    
Author: Lake, B.G. · Rumsby, P.C. · Price, R.J. · Cunninghame, M.E.
Keywords: Hepatic peroxisome proliferation · Replicative DNA synthesis · Species differences · Syrian hamster · Transforming growth factor-β1 · ciprofibrate · messenger RNA · methylclofenapate · peroxisome proliferator · peroxisome proliferator activated receptor · pirinixic acid · somatomedin B receptor · transforming growth factor beta1 · animal model · animal tissue · cell division · controlled study · DNA synthesis · enzyme activity · fatty acid oxidation · liver weight · nonhuman · species difference · Syrian hamster · Animals · Cell Division · Clofenapate · Clofibric Acid · Cricetinae · DNA · Gene Expression · Guinea Pigs · Liver · Male · Mesocricetus · Molecular Structure · Organ Size · Peroxisome Proliferators · Pyrimidines · Rats · Rats, Sprague-Dawley · Receptor, IGF Type 2 · Species Specificity · Transforming Growth Factor beta · Cavia · Cavia porcellus · Cricetinae · Mesocricetus auratus · Rodentia · Sus scrofa · Zea mays
[Abstract]

5 Active TGF-β1 correlates with myofibroblasts and malignancy in the colorectal adenoma-carcinoma sequence
article 2009    
Author: Hawinkels, L.J.A.C. · Verspaget, H.W. · Reijden, J.J. van der · Zon, J.M. van der · Verheijen, J.H. · Hommes, D.W. · Lamers, C.B.H.W. · Sier, C.F.M.
Keywords: Biology · Biomedical Research · actin · desmin · keratin · plasminogen activator inhibitor 1 · Smad2 protein · SMAD2 protein, human · transforming growth factor beta1 · tumor marker · urokinase · vimentin · adenoma · article · carcinoma · cell strain HT29 · colorectal tumor · enzyme linked immunosorbent assay · female · fibroblast · human · immunohistochemistry · male · metabolism · pathology · reproducibility · sensitivity and specificity · smooth muscle · Actins · Adenoma · Carcinoma · Colorectal Neoplasms · Desmin · Enzyme-Linked Immunosorbent Assay · Female · Fibroblasts · HT29 Cells · Humans · Immunohistochemistry · Keratins · Male · Muscle, Smooth · Plasminogen Activator Inhibitor 1 · Reproducibility of Results · Sensitivity and Specificity · Smad2 Protein · Transforming Growth Factor beta1 · Tumor Markers, Biological · Urokinase-Type Plasminogen Activator · Vimentin
[Abstract]

6 Tissue level, activation and cellular localisation of TGF-β1 and association with survival in gastric cancer patients
article 2007    
Author: Hawinkels, L.J.A.C. · Verspaget, H.W. · Duijn, W. van · Zon, J.M. van der · Zuidwijk, K. · Kubben, F.J.G.M. · Verheijen, J.H. · Hommes, D.W. · Lamers, C.B.H.W. · Sier, C.F.M.
Keywords: Biology · Biomedical Research · ELISA · Fibroblast · Immunohistochemistry · Matrix metalloproteinase · Transforming growth factor-β · Tumour microenvironment · proteinase · smooth muscle actin · transforming growth factor beta1 · urokinase · adult · aged · article · cancer survival · comparative study · correlation analysis · enzyme activity · enzyme linked immunosorbent assay · epithelium cell · female · fibroblast · human · human tissue · immunohistochemistry · major clinical study · male · microenvironment · myofibroblast · priority journal · protein expression · protein function · protein localization · smooth muscle · stomach cancer · stomach mucosa · tissue homogenate · Aged · Female · Humans · Immunohistochemistry · Male · Middle Aged · Stomach Neoplasms · Survival Analysis · Transforming Growth Factor beta1
[PDF] [Abstract]

7 Genetic risk factors for autoimmune diseases
article 1999    
Author: Feltkamp, T.E.W. · Aarden, L.A. · Lucas, C.J. · Verweij, C.L. · Vries, R.R.P. de
Keywords: Biology · Animals · Apoptosis · Arthritis, Experimental · Arthritis, Rheumatoid · Autoimmune Diseases · Celiac Disease · Diabetes Mellitus, Type 1 · Genetic Predisposition to Disease · Humans · Interleukin-10 · Mice · Mice, Inbred MRL lpr · Mice, Knockout · Multiple Sclerosis · Risk Factors · Transforming Growth Factor beta · Tumor Necrosis Factor-alpha
[Abstract]

8 Role of caveolin-1 in fibrotic diseases
article 2013    
Author: Gvaramia, D. · Blaauboer, M.E. · Hanemaaijer, R. · Everts, V.
Keywords: Biology · Caveolin-1 · CSD peptide · Fibrosis · Matrix remodeling · Mechanotransduction · TGF-β1 · Antifibrotic agent · Recombinant caveolin 1 · Transforming growth factor beta1 · Unclassified drug · Animal experiment · Animal model · Animal tissue · Controlled study · Human · Mechanical stress · Mouse · Nonhuman · Protein function · Short survey · Tissue repair · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · EELS - Earth, Environmental and Life Sciences
[Abstract]

9 β1 integrins regulate chondrogenesis and rock signaling in adipose stem cells
article 2008    
Author: Lu, Z.F. · Doulabi, B.Z. · Huang, C.L. · Bank, R.A. · Helder, M.N.
Keywords: Health · Biomedical Research · β1 integrins · Adipose tissue · Cell shape · Chondrogenesis · Mesenchymal stem cells · Rock signaling · beta1 integrin · collagen type 10 · collagen type 2 · transcription factor Sox9 · transforming growth factor beta1 · DNA binding protein · high mobility group protein · immunoglobulin G · Rho kinase · sox-9 transcription factor · SOX6 protein, human · transcription factor · adipocyte · article · cell interaction · chondrogenesis · collagen 2 gene · collagen x gene · controlled study · down regulation · extracellular matrix · gene · gene expression · human · human cell · human tissue · priority journal · protein function · rock 1 gene · rock 2 gene · signal transduction · Sox9 gene · adipose tissue · cell shape · culture medium · cytology · drug antagonism · drug effect · gene expression regulation · genetics · physiology · stem cell · Adipose Tissue · Antigens, CD29 · Cell Shape · Chondrogenesis · Collagen Type II · Collagen Type X · Culture Media · DNA-Binding Proteins · Gene Expression · Gene Expression Regulation, Developmental · High Mobility Group Proteins · Humans · Immunoglobulin G · rho-Associated Kinases · Stem Cells · Transcription Factors · Transforming Growth Factor beta1 · Healthy for Life · Healthy Living
[Abstract]

10 Elevated expression levels of lysyl oxidases protect against aortic aneurysm progression in Marfan syndrome
article 2015    
Author: Busnadiego, O. · Gorbenko del Blanco, D. · González-Santamaría, J. · Habashi, J.P. · Calderon, J.F. · Sandoval, P. · Bedja, D. · Guinea-Viniegra, J. · Lopez-Cabrera, M. · Rosell-Garcia, T. · Snabel, J.M. · Hanemaaijer, R. · Forteza, A. · Dietz, H.C. · Egea, G. · Rodriguez-Pascual, F.
Keywords: Biology · Aneurysm · Collagen · Extracellular matrix · Lysyl oxidases · Marfan syndrome · Transforming growth factor-β · Losartan · Oxidoreductase · Protein LOXL1 · Protein lysine 6 oxidase · Transforming growth factor beta · Unclassified drug · Animal tissue · Aorta aneurysm · Clinical article · Collagen fiber · Controlled study · Disease association · Disease course · Disease severity · Elastic fiber · Enzyme inhibition · Human tissue · Marfan syndrome · Mouse · Mouse model · Nonhuman · Prophylaxis · Protein expression · Signal transduction · Upregulation · Wild type · Animalia · Mus · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · ELSS - Earth, Life and Social Sciences
[Abstract]

11 Network-based integration of molecular and physiological data elucidates regulatory mechanisms underlying adaptation to high-fat diet
article 2015    
Author: Derous, D. · Kelder, T. · Schothorst, E.M. van · Erk, M. van · Voigt, A. · Klaus, S. · Keijer, J. · Radonjic, M.
Keywords: Adipose tissue · Data integration · High-fat diet · Network analysis · Systems biology · Transcriptional regulation · Transcriptomics · Transforming growth factor beta · Adaptation · Analytic method · Animal tissue · Caloric intake · Cell respiration · Controlled study · Disorders of mitochondrial functions · Down regulation · Epididymis fat · Gene expression · Immune response · Lipid diet · Low fat diet · Male · Metabolic regulation · Mouse · Network analysis · Nonhuman · Organ weight · Signal transduction · Stress · Transcription regulation · White adipose tissue · Murinae · Biomedical Innovation · Healthy Living · Life · MSB - Microbiology and Systems Biology · ELSS - Earth, Life and Social Sciences
[PDF] [Abstract]

12 Synovial inflammation, immune cells and their cytokines in osteoarthritis: A review
article 2012    
Author: Lange-Brokaar, B.J.E. de · Ioan-Facsinay, A. · Osch, G.J.V.M. van · Zuurmond, A.-M. · Schoones, J. · Toes, R.E.M. · Huizinga, T.W.J. · Kloppenburg, M.
Keywords: Cytokines · Histology · Immune cells · Inflammation · Osteoarthritis · Synovial tissue · gamma interferon · interleukin 10 · interleukin 18 · interleukin 1beta · interleukin 2 · interleukin 4 · interleukin 6 · interleukin 8 · transforming growth factor beta · tumor necrosis factor alpha · cell infiltration · cytokine release · hip arthroplasty · immunocompetent cell · immunohistochemistry · information retrieval · knee arthroscopy · macrophage · mast cell · needle biopsy · osteoarthritis · priority journal · review · rheumatoid arthritis · synovectomy · synovitis · T lymphocyte · Healthy Living · Life · MHR - Metabolic Health Research · EELS - Earth, Environmental and Life Sciences
[Abstract]

13 TGFβ affects collagen cross-linking independent of chondrocyte phenotype but strongly depending on physical environment
article 2008    
Author: Bastiaansen-Jenniskens, Y.M. · Koevoet, W. · Bart, A.C.W. de · Zuurmond, A.-M. · Bank, R.A. · Verhaar, J.A.N. · Groot, J. de · Osch, G.J.V.M. van
Keywords: Biology · Alginate · Body fluids · Cell proliferation · Cells · Cobalt · Cobalt compounds · Collagen · Colloids · Electron energy levels · Fibroblasts · Gelation · Matrix algebra · Painting · Photoacoustic effect · Shape memory effect · Technology · Tissue · Tissue culture · Tissue engineering · Alginate gel (AG) · Cartilage tissue engineering · Cell populations · Chondrocyte · Chondrocytes · Collagen cross-linking · Collagen deposition · Cultures (Traditional) · Matrix formation · Mechanical stressing · Monolayer cultures · Physical environments · Primary cells · Shape memory alloy (SMA) fibers · Smooth muscle actin (SMA) · Tissue culture plastic (TCP) · Transforming Growth Factor (TGF) · Cell culture · Alginic acid · Alpha smooth muscle actin · Collagen · Transforming growth factor beta · Actin · Collagen type 1 · Collagen type 2 · Cross linking reagent · DNA · Transcription factor Sox9 · Transforming growth factor beta2 · Animal cell · Animal tissue · Article · Calf (bovine) · Cartilage cell · Cell population · Controlled study · Cross linking · Drug effect · Fibroblast · Nonhuman · Phenotype · Priority journal · Upregulation · Animal · Cattle · Cell culture · Cytology · Extracellular matrix · Gene expression regulation · Genetics · Immunohistochemistry · Metabolism · Smooth muscle · Actins · Animals · Cattle · Cells, Cultured · Chondrocytes · Collagen · Collagen Type I · Collagen Type II · Cross-Linking Reagents · DNA · Extracellular Matrix · Gene Expression Regulation · Immunohistochemistry · Muscle, Smooth · Phenotype · SOX9 Transcription Factor · Transforming Growth Factor beta2
[PDF] [Abstract]

14 Human embryo-conditioned medium stimulates in vitro endometrial angiogenesis
article 2006    
Author: Kapiteijn, K. · Koolwijk, P. · Weiden, R.M.F. van der · Nieuw Amerongen, G. van · Plaisier, M. · Hinsbergh, V.W.M. van · Helmerhorst, F.M.
Keywords: Biology · Biomedical Research · Endometrial angiogenesis · Leukemia inhibitory factor · Placental growth factor · Recombinant chorionic gonadotropin · Recombinant colony stimulating factor 1 · Recombinant epidermal growth factor · Recombinant gamma interferon · Recombinant interleukin 10 · Recombinant interleukin 6 · Recombinant platelet derived growth factor · Recombinant somatomedin B · Recombinant somatomedin C · Recombinant transforming growth factor beta · Transforming growth factor alpha · Vasculotropin A · Vasculotropin receptor 1 · Angiogenesis · Cell growth · Controlled study · Culture medium · Drug effect · Embryo · Edometrium · Endometrium cell · Endothelium cell · Enzyme linked immunosorbent assay · Female · Human cell · Human embryo · Implantation · In vitro study · Priority journal · Stimulation · Trophoblast · Angiogenic Proteins · Cell Culture Techniques · Cell Proliferation · Cell Survival · Cells, Cultured · Culture Media, Conditioned · Neovascularization, Physiologic · Tissue Engineering
[Abstract]

15 Molecular markers for osteoarthritis: The road ahead
article 2002    
Author: Groot, J. de · Bank, R.A. · Tchetverikov, I. · Verzijl, N. · TeKoppele, J.M.
Keywords: Biology · Biomedical Research · biological marker · cartilage oligomeric matrix protein · chondroitin sulfate · collagen · collagen type 2 · cytokine · epitope · hyaluronic acid · keratan sulfate · matrix metalloproteinase · osteocalcin · proteoglycan · sialoprotein · tissue inhibitor of metalloproteinase · transforming growth factor beta1 · tumor necrosis factor receptor 2 · cross linking reagent · arthritis · articular cartilage · collagen synthesis · cross linking · disease course · inflammation · prognosis · review · synovium · extracellular matrix · genetic marker · genetics · metabolism · pathology · Collagen Type II · Cross-Linking Reagents · Extracellular Matrix · Genetic Markers · Matrix Metalloproteinases · Osteoarthritis · Proteoglycans · Support, Non-U.S. Gov't · Humans
[Abstract]

16 Studies on the mechanism of fibrate-inhibited expression of plasminogen activator inhibitor-1 in cultured hepatocytes from cynomolgus monkey
article 1997    
Author: Arts, J. · Kooistra, T.
Keywords: Biology · 9-cis retinoic acid · fibrates · hepatocytes · peroxisome proliferator-activated receptor · plasminogen activator inhibitor-1 · 2 [1 (3 amidinothiopropyl) 1h indol 3 yl] 3 (1 methyl 1h indol 3 yl)maleimide · alitretinoin · antilipemic agent · epidermal growth factor · fibric acid derivative · gemfibrozil · peroxisome proliferator · phorbol 13 acetate 12 myristate · plasminogen activator inhibitor 1 · protein kinase C · protein kinase C inhibitor · retinoid X receptor · transforming growth factor beta · animal cell · controlled study · dose time effect relation · drug mechanism · enzyme activity · gene expression · hyperlipidemia · liver cell culture · monkey · nonhuman · Animals · Antilipemic Agents · Cells, Cultured · Dose-Response Relationship, Drug · Liver · Macaca fascicularis · Plasminogen Activator Inhibitor 1 · RNA, Messenger
[Abstract]

17 Mediators of apoptosis Fas and FasL predict disability progression in multiple sclerosis over a period of 10 years
article 2006    
Author: Lopatinskaya, L. · Zwemmer, J. · Uitdehaag, B. · Lucas, K. · Polman, C. · Nagelkerken, L.
Keywords: Biomedical Research · Apoptosis · Chemokines · Cytokines · EDSS · Fas · MS · chemokine receptor CCR3 · chemokine receptor CCR5 · chemokine receptor CXCR3 · Fas antigen · FAS ligand · interleukin 10 · interleukin 12p35 · interleukin 12p40 · interleukin 4 · messenger RNA · OKT 4 · osteopontin · transforming growth factor beta1 · tumor necrosis factor alpha · adult · apoptosis · article · clinical article · controlled study · correlation analysis · disability · disease association · disease course · Expanded Disability Status Scale · female · human · human cell · male · multiple sclerosis · pathophysiology · peripheral blood mononuclear cell · post hoc analysis · prediction · quantitative analysis · real time polymerase chain reaction · relapse · remission · Adult · Antibodies, Monoclonal · Antigens, CD95 · Apoptosis · Biological Markers · Chemokines · Cytokines · Disability Evaluation · Fas Ligand Protein · Female · Follow-Up Studies · Humans · Male · Middle Aged · Multiple Sclerosis, Chronic Progressive · Multiple Sclerosis, Relapsing-Remitting · Predictive Value of Tests · RNA, Messenger
[Abstract]

18 αB-crystallin is a target for adaptive immune responses and a trigger of innate responses in preactive multiple sclerosis lesions
article 2010    
Author: Noort, J.M. van · Bsibsi, M. · Gerritsen, W.H. · Valk, P. van der · Bajramovic, J.J. · Steinman, L. · Amor, S.
Keywords: Biology · Biomedical Research · αB-crystallin · Autoantibodies · Microglia · Multiple sclerosis · Preactive lesions · alpha B crystallin · antibody · CCL1 chemokine · chemokine · crystallin · HLA DR antigen · immunoglobulin G · interleukin 10 · interleukin 13 · interleukin 17 · myelin protein · transforming growth factor beta · tumor necrosis factor · unclassified drug · alpha crystallin · basic helix loop helix transcription factor · cytokine · glial fibrillary acidic protein · nerve protein · neurofilament protein · neurofilament protein L · OLIG2 protein, human · proteolipid protein · adaptive immunity · adult · antibody blood level · article · cell activation · clinical article · controlled study · human · immunoglobulin blood level · innate immunity · male · microglia · multiple sclerosis · priority journal · protein secretion · white matter · immunology · mass spectrometry · metabolism · methodology · middle aged · oligodendroglia · pathology · pathophysiology · physiology · Adaptive Immunity · Adult · alpha-Crystallins · Basic Helix-Loop-Helix Transcription Factors · Cytokines · Glial Fibrillary Acidic Protein · HLA-DR Antigens · Humans · Mass Spectrometry · Microglia · Middle Aged · Multiple Sclerosis · Myelin Proteolipid Protein · Nerve Tissue Proteins · Neurofilament Proteins · Oligodendroglia
[Abstract]

19 Initiating mechanisms of food allergy: Oral tolerance versus allergic sensitization
article 2007    
Author: Wijk, F. van · Knippels, L.
Keywords: Nutrition · Toxicology and Applied Pharmacology · Dendritic cells · Food allergy · Oral tolerance · Regulatory T cells · allergen · B7 antigen · CD28 antigen · CD40 antigen · CD40 ligand · CD86 antigen · cytotoxic T lymphocyte antigen 4 · food antigen · gamma interferon · immunoglobulin A antibody · immunoglobulin E · interleukin 10 · neutralizing antibody · ovalbumin · peanut antigen · probiotic agent · transforming growth factor beta · tumor necrosis factor alpha · adaptive immunity · allergenicity · antibody production · antigen presenting cell · article · B lymphocyte · body surface · bystander effect · CD4+ CD25+ T lymphocyte · cell activation · cell interaction · cell maturation · cell subpopulation · cellular immunity · commensal · dendritic cell · food allergy · gastrointestinal mucosa · human · immune response · immune system · immunological tolerance · immunotherapy · innate immunity · intestine lymphatic tissue · intestine wall · lamina propria · lymphocyte · lymphoid tissue · mesentery lymph node · microenvironment · nonhuman · peanut allergy · Peyer patch · priority journal · protein analysis · protein intake · protein localization · regulatory T lymphocyte · signal transduction · T lymphocyte · T lymphocyte activation · Th3 cell · Antigens, CD · Food Hypersensitivity · Glycoproteins · Humans · Immune Tolerance · Immunization · Intestinal Mucosa · Lymph Nodes · Peyer's Patches · Receptors, Antigen, T-Cell
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 19 of 19 found. | Sort by date