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1 Differential binding of methyl benzimidazol 2 yl carbamate to fungal tubulin as a mechanism of resistance to this antimiotic agent in mutant strains of Aspergillus nidulans
article 1977    
Author: Davidse, L.C. · Flach, W.
Keywords: benomyl · carbon 14 · colchicine · fuberidazole · mebendazole · nocodazole · r 17 934 · radioisotope · tiabendazole · aspergillus nidulans · colchicine h 3 · drug binding · drug protein binding · drug resistance · microorganism · mutant · theoretical study · Aspergillus nidulans · Benzimidazoles · Binding, Competitive · Carbamates · Colchicine · Drug Resistance · Glycoproteins · Griseofulvin · Hydrogen-Ion Concentration · Melatonin · Mutation · Podophyllotoxin · Receptors, Drug · Temperature · Tubulin · Vinblastine
[Abstract]

2 Profiling of endogenous peptides in human synovial fluid by NanoLC-MS : Method validation and peptide identification
article 2007    
Author: Kamphorst, J.J. · Heijden, R. van der · Groot, J. de · Lafeber, F.P.J.G. · Reijmers, T.H. · El, B. van · Tjaden, U.R. · Greef, J. van der · Hankemeier, T.
Keywords: Biology · Biomedical Research · Biomarker · High-resolution MS · NanoLC-MS · Orbitrap · Osteoarthritis · Peptide profiling · Peptidomics · Synovial fluid · amyloid A protein · collagen type 2 · hyaluronic acid · proteoglycan · tubulin · vimentin · article · clinical article · controlled study · human · liquid chromatography · mass spectrometry · nucleotide sequence · osteoarthritis · peptide analysis · priority journal · solid phase extraction · synovial fluid · ultrafiltration · validation study · Amino Acid Sequence · Arthritis, Rheumatoid · Biological Markers · Chromatography, Liquid · Gene Expression Profiling · Humans · Mass Spectrometry · Molecular Sequence Data · Osteoarthritis · Peptides · Proteins · Proteomics · Reproducibility of Results · Synovial Fluid
[Abstract]

3 Profiles of metabolites and gene expression in rats with chemically induced hepatic necrosis
article 2005    
Author: Heijne, W.H.M. · Lamers, R.J.A.N. · Bladeren, P.J. van · Groten, J.P. · Nesselrooij, J.H.J. van · Ommen, B. van
Keywords: Biology · Physiological Sciences · Bromobenzene · Centrilobular necrosis · Hepatotoxicity · Metabolite profiling · Metabolomics · Toxicogenomics · Transcriptomics · alanine · asialoglycoprotein receptor · beta actin · bromobenzene · casein kinase II · creatine · creatinine · cyclin G1 · cycline · dimethylglycine · ferritin · fibrinogen · fructose bisphosphate aldolase · glyceraldehyde 3 phosphate dehydrogenase · lactic acid · methionine · nucleophosmin · orosomucoid · peroxiredoxin · phosphatidylcholine sterol acyltransferase · phosphoglycerate mutase · phospholipid · protein bcl 2 · protein p21 · protein p53 · taurine · tissue inhibitor of metalloproteinase 1 · tubulin · tyrosine · unindexed drug · amino acid metabolism · animal model · apoptosis · article · blood level · controlled study · DNA microarray · dose response · gene · gene expression · gene sequence · glycolysis · liver necrosis · liver toxicity · male · metabolomics · nonhuman · nuclear magnetic resonance spectroscopy · nucleotide sequence · priority journal · rat · transcriptomics · urine level · Amino Acids · Animals · Bromobenzenes · Dose-Response Relationship, Drug · Gene Expression Profiling · Hepatitis, Toxic · Liver · Male · Necrosis · Principal Component Analysis · Rats · Rats, Wistar · Transcription, Genetic
[Abstract]

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