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1 Inhibition of MMP synthesis by doxycycline and chemically modified tetracyclines (CMTs) in human endothelial cells
article 1998    
Author: Hanemaaijer, R. · Visser, H. · Koolwijk, P. · Sorsa, T. · Salo, T. · Golub, L.M. · Hinsbergh, V.W. van
Keywords: Health · Anti-Bacterial Agents · Cells, Cultured · Doxycycline · Endothelium · Humans · Metalloendopeptidases · Protease Inhibitors · Tetracyclines · Tetradecanoylphorbol Acetate · Tumor Necrosis Factor-alpha
[Abstract]

2 Genistein reduces tumor necrosis factor α-induced plasminogen activator inhibitor-1 transcription but not urokinase expression in human endothelial cells
article 1994    
Author: Hinsbergh, V.W.M. van · Vermeer, M. · Koolwijk, P. · Grimbergen, J. · Kooistra, T.
Keywords: Health · bacterium lipopolysaccharide · daidzein · genistein · herbimycin a · plasminogen activator · protein tyrosine phosphatase · transcription factor · tumor necrosis factor alpha · tyrphostin · urokinase · vanadic acid · cell migration · endothelium cell · enzyme activation · enzyme inhibition · fibrinolysis · genetic transcription · human cell · mitogenesis · plasminogen activation · priority journal · signal transduction · Cells, Cultured · Endothelium, Vascular · Fibroblast Growth Factor 2 · Genistein · Human · In Vitro · Isoflavones · Plasminogen Activator Inhibitor 1 · Protein-Tyrosine Kinase · Receptors, Tumor Necrosis Factor · Signal Transduction · Support, Non-U.S. Gov't · Tissue Plasminogen Activator · Tumor Necrosis Factor · Urinary Plasminogen Activator
[Abstract]

3 Tumor necrosis factor induces the production of urokinase-type plasminogen activator by human endothelial cells
article 1990    
Author: Hinsbergh, V.W.M. van · Berg, E.A. van den · Fiers, W. · Dooijewaard, G.
Keywords: Biological Factors · Cells, Cultured · Cytokines · Endothelium, Vascular · Fibrinolytic Agents · Gene Expression Regulation · Human · Plasmin · Plasminogen Activators · Plasminogen Inactivators · RNA, Messenger · Tumor Necrosis Factor · Urinary Plasminogen Activator
[Abstract]

4 Can hTNF-alpha be successfully produced and secreted in filamentous fungus Aspergillus niger?
article 2000    
Author: Krasevec, N. · Hondel, C.A.M.J.J. van den · Komel, R.
Keywords: Aspergillus niger · Heterologous protein secretion · hTNF-α · hTNF-α analogues · Glucan 1,4 alpha glucosidase · Tumor necrosis factor alpha · Amino acid sequence · Aspergillus niger · Biosynthesis · Gene expression · Gene fusion · Genetics · Human · Metabolism · Secretion · Amino Acid Sequence · Artificial Gene Fusion · Aspergillus niger · Gene Expression · Glucan 1,4-alpha-Glucosidase · Humans · Tumor Necrosis Factor-alpha
[Abstract]

5 Tumor necrosis factor increases the production of plasminogen activator inhibitor in human endothelial cells in vitro and in rats in vivo
article 1988    
Author: Hinsbergh, V.W.M. van · Kooistra, T. · Berg, E.A. van den · Princen, H.M.G. · Fiers, W. · Emeis, J.J.
Keywords: Interleukin 1 · Interleukin 6 · Lymphotoxin · Plasminogen activator inhibitor · Radioisotope · Tumor necrosis factor · Animal experiment · Animal model · Cell culture · Endothelium cell · Human · Human cell · Intravenous drug administration · Liver cell · Nonhuman · Animal · Blotting, Northern · Cells, Cultured · Endothelium, Vascular · Gene Expression Regulation · Glycoproteins · In Vitro · Lymphotoxin · Male · Plasminogen Inactivators · Rats · Rats, Inbred Strains · RNA, Messenger · Support, Non-U.S. Gov't · Tissue Plasminogen Activator · Tumor Necrosis Factor
[Abstract]

6 Differential regulation of interleukin-10 (IL-10) and IL-12 by glucocorticoids in vitro
article 1998    
Author: Visser, J. · Boxel-Dezaire, A. van · Methorst, D. · Brunt, T. · Kloet, E.R. de · Nagelkerken, L.
Keywords: Health · Antigen-Presenting Cells · Cells, Cultured · Dexamethasone · Female · Glucocorticoids · Hormone Antagonists · Humans · Hydrocortisone · Interleukin-10 · Interleukin-12 · Lipopolysaccharides · Male · Mifepristone · Receptors, Glucocorticoid · RNA, Messenger · Th1 Cells · Th2 Cells · Tumor Necrosis Factor-alpha · Up-Regulation
[Abstract]

7 Characterization and fibrinolytic properties of human omental tissue mesothelial cells. Comparison with endothelial cells
article 1990    
Author: Hinsbergh, V.W.M. van · Kooistra, T. · Scheffer, M.A. · Bockel, J.H. van · Muijen, G.N.P. van
Keywords: Adipose Tissue · Biological Markers · Cells, Cultured · Endothelium, Vascular · Enzyme-Linked Immunosorbent Assay · Fibrinolysis · Human · Lipopolysaccharides · Omentum · Organ Specificity · Plasminogen Activators · Plasminogen Inactivators · Protein Precursors · Recombinant Proteins · Tissue Plasminogen Activator · Tumor Necrosis Factor
[Abstract]

8 Tumor necrosis factor α induces endothelial galactosyl transferase activity and verocytotoxin receptors. Role of specific tumor necrosis factor receptors and protein kinase C
article 1995    
Author: Kar, N.C.A.J. van de · Kooistra, T. · Vermeer, M. · Lesslauer, W. · Monnens, L.A.H. · Hinsbergh, V.W.M. van
Keywords: Toxicology · 1 (5 isoquinolinesulfonyl) 2 methylpiperazine · 2 [1 (3 amidinothiopropyl) 1h indol 3 yl] 3 (1 methyl 1h indol 3 yl)maleimide · endothelial leukocyte adhesion molecule 1 · galactosyltransferase · globotriaosylceramide · interleukin 1 · n (2 guanidinoethyl) 5 isoquinolinesulfonamide · phorbol 13 acetate 12 myristate · phorbol ester · plasminogen activator inhibitor 1 · protein kinase C · protein kinase C inhibitor · recombinant interleukin 1beta · recombinant tumor necrosis factor alpha · tumor necrosis factor receptor · verotoxin · article · autoradiography · controlled study · endothelium cell · endothelium injury · gene expression · hemolytic uremic syndrome · human · human cell · priority journal · protein synthesis inhibition · signal transduction · umbilical vein · Autoradiography · Bacterial Toxins · Carbon Radioisotopes · Cell Adhesion Molecules · Cells, Cultured · Cytotoxins · E-Selectin · Endothelium, Vascular · Enzyme Induction · Galactose · Galactosyltransferases · Glucose · Glycolipids · Human · Kinetics · Protein Kinase C · Receptors, Cell Surface · Receptors, Tumor Necrosis Factor · Shiga-Like Toxin I · Support, Non-U.S. Gov't · Tumor Necrosis Factor · Umbilical Veins
[Abstract]

9 Progress of fibrinolysis during tumor necrosis factor infusions in humans. Concomitant increase in tissue-type plasminogen activator, plasminogen activator inhibitor type-1, and fibrin(ogen) degradation products
article 1990    
Author: Hinsbergh, V.W.M. van · Bauer, K.A. · Kooistra, T. · Kluft, C. · Dooijewaard, G. · Sherman, M.L. · Nieuwenhuizen, W.
Keywords: Biology · Fibrin Fibrinogen Degradation Products · Fibrinolysis · Human · Kinetics · Neoplasms · Plasmin · Plasminogen Inactivators · Recombinant Proteins · Support, Non-U.S. Gov't · Support, U.S. Gov't, P.H.S. · Tissue Plasminogen Activator · Tumor Necrosis Factor · Urinary Plasminogen Activator
[Abstract]

10 Matrix metalloproteinase-8 is expressed in rheumatoid synovial fibroblasts and endothelial cells: Regulation by tumor necrosis factor-α and doxycycline
article 1997    
Author: Hanemaaijer, R. · Sorsa, T. · Konttinen, Y.T. · Ding, Y. · Sutinen, M. · Visser, H. · Hinsbergh, V.W.M. van · Helaakoski, T. · Kainulainen, T. · Rönkä, H. · Tschesche, H. · Salo, T.
Keywords: Arthritis, Rheumatoid · Catalysis · Cells, Cultured · Collagenases · Doxycycline · Endothelium · Endothelium, Vascular · Enzyme Inhibitors · Fibroblasts · Glycosylation · Humans · Matrix Metalloproteinase 8 · RNA, Messenger · Synovial Membrane · Tetradecanoylphorbol Acetate · Tumor Necrosis Factor-alpha · Up-Regulation
[PDF] [Abstract]

11 The influence of microbial metabolites on human intestinal epithelial cells and macrophages in vitro
article 2005    
Author: Nuenen, M.H.M.C. van · Ligt, R.A.F. de · Doornbos, R.P. · Woude, J.C.J. van der · Kuipers, E.J. · Venema, K.
Keywords: Nutrition · Physiological Sciences · Interleukin-10 · Intestinal epithelial cells · Macrophages · Microbial metabolites · Tumour necrosis factor-α · ammonia · butyric acid · cytokine · interleukin 10 · tumor necrosis factor alpha · valeric acid · article · cell strain CACO 2 · concentration (parameters) · cytokine release · electric resistance · enteritis · epithelium cell · human · human cell · immunity · macrophage · metabolism · metabolite · physiology · priority journal · Ammonium Chloride · Butyrates · Caco-2 Cells · Epithelial Cells · Humans · Immunity, Mucosal · Inflammatory Bowel Diseases · Interleukin-10 · Intestines · Macrophages · Pentanoic Acids · Tumor Necrosis Factor-alpha · U937 Cells
[Abstract]

12 Effects of verocytotoxin-1 on nonadherent human monocytes: Binding characteristics, protein synthesis, and induction of cytokine release
article 1996    
Author: Setten, P.A. van · Monnens, L.A.H. · Verstraten, R.G.G. · Heuvel, L.P.W.J. van den · Hinsbergh, V.W.M. van
Keywords: Biology · Cytokine · Globotriaosylceramide · Messenger rna · Tumor necrosis factor alpha · Verotoxin · Cell stimulation · Controlled study · Enterobacter infection · Escherichia coli · Glomerulus · Hemolytic uremic syndrome · Human cell · Inflammation · Protein synthesis · Reverse transcription polymerase chain reaction · Bacterial Toxins · Binding Sites · Cell Culture Techniques · Cell Survival · Cells, Cultured · Escherichia coli · Gene Expression Regulation · Hemolytic-Uremic Syndrome · Humans · Interleukin-1 · Interleukin-6 · Interleukin-8 · Interleukins · Ligands · Lipopolysaccharides · Male · Monocytes · Polytetrafluoroethylene · Protein Biosynthesis · Shiga-Like Toxin I · Trihexosylceramides · Tumor Necrosis Factor-alpha
[Abstract]

13 Participation of β-adrenergic receptors on macrophages in modulation of LPS-induced cytokine release
article 1999    
Author: Izeboud, C.A. · Mocking, J.A.J. · Monshouwer, M. · Miert, A.S.J.P.A.M. van · Witkamp, R.F.
Keywords: Nutrition · Beta 2 adrenergic receptor stimulating agent · Beta adrenergic receptor · Clenbuterol · Cytokine · Interleukin 10 · Interleukin 6 · Lipopolysaccharide · Radioligand · Tumor necrosis factor alpha · Antiinflammatory activity · Cell culture · Conference paper · Cytokine production · Drug receptor binding · Human · Human cell · Inflammation · Macrophage · Macrophage activation · Monocyte · Receptor binding · Receptor intrinsic activity · Adrenergic beta-Agonists · Adrenergic beta-Antagonists · Atenolol · Clenbuterol · Cytokines · Humans · Interleukin-10 · Interleukin-6 · Lipopolysaccharides · Macrophage Activation · Macrophages · Propanolamines · Receptors, Adrenergic, beta · Tumor Necrosis Factor-alpha · U937 Cells
[Abstract]

14 The β-adrenoceptor agonist clenbuterol is a potent inhibitor of the LPS-induced production of TNF-α and IL-6 in vitro and in vivo
article 1999    
Author: Izeboud, C.A. · Monshouwer, M. · Miert, A.S.J.P.A.M. van · Witkamp, R.F.
Keywords: Nutrition · β-agonists · Clenbuterol · Cytokines · Lipopolysaccharide · Macrophages · Beta adrenergic receptor stimulating agent · Clenbuterol · Interleukin 6 · Lipopolysaccharide · Tumor necrosis factor alpha · Animal cell · Bioassay · Blood level · Controlled study · Culture medium · Cytokine production · Enzyme linked immunosorbent assay · Human · Human cell · Inflammation · Macrophage · Male · Monocyte · Nonhuman · Oral drug administration · Rat · Adrenergic beta-Agonists · Animals · Cell Line · Clenbuterol · Escherichia coli · Humans · Interleukin-6 · Lipopolysaccharides · Macrophages · Male · Rats · Rats, Wistar · Tumor Necrosis Factor-alpha
[Abstract]

15 Impact of apolipoprotein(a) on in vitro angiogenesis
article 2001    
Author: Schulter, V. · Koolwijk, P. · Peters, E. · Frank, S. · Hrzenjak, A. · Graier, W.F. · M. van Hinsbergh, V.W. · Kostner, G.M.
Keywords: Health · Endothelial cells · Kringle · Lp(a) · Urinary fragments · Angiostatin · Apolipoprotein A · Basic fibroblast growth factor · Fibrin · Plasminogen · Recombinant protein · Tumor necrosis factor alpha · Urokinase · Angiogenesis · Cell proliferation · Concentration (parameters) · Controlled study · Endothelium cell · Human cell · Kringle domain · Lipid analysis · Protein expression · Protein secretion · Angiogenesis Inhibitors · Apolipoproteins A · Cell Division · Cells, Cultured · Dose-Response Relationship, Drug · Endothelium, Vascular · Fibroblast Growth Factor 2 · Humans · Male · Peptide Fragments · Plasminogen Activator Inhibitor 1 · Tumor Necrosis Factor-alpha · Urinary Plasminogen Activator
[Abstract]

16 Inhibiting interleukin-1 and tumor necrosis factor-α does not reduce induction of plasminogen activator inhibitor type-1 by endotoxin in rats in vivo
article 1995    
Author: Emeis, J.E. · Hoekzema, R. · Vos, A.F. de
Keywords: Toxicology · corticosterone · dexamethasone · escherichia coli endotoxin · escherichia coli lipopolysaccharide · interleukin 1 · interleukin 1 receptor blocking agent · pentoxifylline · plasminogen activator inhibitor 1 · tissue plasminogen activator · tumor necrosis factor alpha · animal experiment · animal model · article · drug effect · drug screening · endotoxemia · intravenous drug administration · male · nonhuman · priority journal · rat · toxicity testing · toxin analysis · Animal · Dexamethasone · Drug Interactions · Endotoxins · Human · Immune Sera · Interleukin-1 · Male · Mice · Pentoxifylline · Plasminogen Activator Inhibitor 1 · Rats · Rats, Wistar · Receptors, Interleukin-1 · Tissue Plasminogen Activator · Tumor Necrosis Factor
[Abstract]

17 The fibrinolytic system in the hemolytic uremic syndrome: In vivo and in vitro studies
article 1994    
Author: Kar, N.C.A.J. van de · Hinsbergh, V.W.M. van · Brommer, E.J.P. · Monnens, L.A.H.
Keywords: Health · Argipressin[1 deamino] · Plasminogen activator inhibitor 1 · Tumor necrosis factor alpha · Verotoxin · Blood level · Child · Clinical article · Endothelium cell · Hemolytic uremic syndrome · Pathogenesis · Priority journal · Protein synthesis · Bacterial Toxins · Cells, Cultured · Child, Preschool · Desmopressin · Endothelium, Vascular · Female · Fibrin Fibrinogen Degradation Products · Fibrinolysis · Hemolytic-Uremic Syndrome · Human · In Vitro · Infant · Male · Plasminogen Activator Inhibitor 1 · Shiga-Like Toxin I · Support, Non-U.S. Gov't · Tissue Plasminogen Activator · Tumor Necrosis Factor · von Willebrand Factor
[Abstract]

18 Elevated formation of pyridinoline cross-links by profibrotic cytokines is associated with enhanced lysyl hydroxylase 2b levels
article 2005    
Author: Slot, A.J. van der · Dura, E.A. van · Wit, E.C. de · Groot, J. de · Huizinga, T.W.J. · Bank, R.A. · Zuurmond, A.M.
Keywords: Lysyl hydroxylase 2b · Pyridinoline · TGF-β · Activin A · Protein lysine 6 oxidase · Transforming growth factor beta · Tumor necrosis factor alpha · Controlled study · Cross linking · Human cell · Protein expression · Skin fibroblast · Skin fibrosis · Upregulation · Activins · Amino Acids · Cells, Cultured · Collagen Type I · Cross-Linking Reagents · Cytokines · Fibroblasts · Fibrosis · Gene Expression Regulation, Enzymologic · Humans · Inhibin-beta Subunits · Interleukin-4 · Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase · Protein Isoforms · RNA, Messenger · Skin · Time Factors · Transforming Growth Factor beta · Tumor Necrosis Factor-alpha · Up-Regulation
[Abstract]

19 Thalidomide inhibits UVB-induced mouse keratinocyte apoptosis by both TNF-α-dependent and TNF-α-independent pathways
article 2003    
Author: Lu, K.Q. · Brenneman, S. · Burns Jr., R. · Vink, A. · Gaines, E. · Haake, A. · Gaspari, A.
Keywords: Toxicology Biology · Toxicology and Applied Pharmacology · α-N-phthalimido-glutarimide · Mouse model · Photoprotection · Sunburn cell · Ultraviolet light · antiinflammatory agent · apoptosis inhibitor · cell DNA · cyclobutane derivative · cytokine · dimer · drug vehicle · messenger RNA · pyrimidine derivative · recombinant tumor necrosis factor alpha · thalidomide · tumor necrosis factor alpha · animal cell · animal experiment · animal model · animal tissue · antiinflammatory activity · apoptosis · article · biosynthesis · bolus injection · cell assay · cell death · controlled study · cytokine production · DNA damage · dose response · drug blood level · drug mechanism · drug megadose · female · histopathology · hypothesis · immunostimulation · in vitro study · keratinocyte · low drug dose · monocyte · mouse · newborn · nick end labeling · nonhuman · photosensitivity disorder · priority journal · radiation dose · radiation exposure · radiation injury · ribonuclease protection assay · skin · skin biopsy · skin lupus erythematosus · steady state · sunburn · ultraviolet B radiation · Animals · Anti-Inflammatory Agents, Non-Steroidal · Apoptosis · Disease Models, Animal · Dose-Response Relationship, Drug · Erythema · Female · Injections, Intravenous · Keratinocytes · Mice · Mice, Inbred BALB C · RNA, Messenger · Thalidomide · Tumor Necrosis Factor-alpha · Ultraviolet Rays
[Abstract]

20 Effect of the anti-tumor necrosis factor-α antibody infliximab on the ex vivo mucosal matrix metalloproteinase-proteolytic phenotype in inflammatory bowel disease
article 2007    
Author: Meijer, M.J. · Mieremet-Ooms, M.A.C. · Duijn, W. van · Zon, A.M. van der · Hanemaaijer, R. · Verheijen, J.H. · Hogezand, R.A. van · Lamers, C.B.H.W. · Verspaget, H.W.
Keywords: Biomedical Research · Inflammatory bowel disease · Infliximab · Matrix metalloproteinase · Tissue inhibitor of metalloproteinase · Tumor necrosis factor-alpha · azathioprine · cyclosporin · gelatinase A · gelatinase B · infliximab · interstitial collagenase · mesalazine · messenger RNA · pokeweed mitogen · steroid · stromelysin · tissue inhibitor of metalloproteinase 1 · tissue inhibitor of metalloproteinase 2 · tumor necrosis factor alpha antibody · adolescent · adult · aged · article · clinical article · controlled study · Crohn disease · drug effect · enteritis · explant · female · genotype · human · human tissue · intestine mucosa · male · priority journal · protein degradation · protein expression · single nucleotide polymorphism · ulcerative colitis · Adolescent · Adult · Aged · Antibodies, Monoclonal · Colitis, Ulcerative · Crohn Disease · Down-Regulation · Female · Humans · Intestinal Mucosa · Male · Matrix Metalloproteinases · Middle Aged · Phenotype · Polymorphism, Single Nucleotide · Reverse Transcriptase Polymerase Chain Reaction · Tissue Culture Techniques · Tissue Inhibitor of Metalloproteinases · Tumor Necrosis Factor-alpha
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 83 found. Next | Sort by date