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1 Pharmacokinetics of cisplatin with and without amifostine in tumour- bearing nude mice
article 1998    
Author: Korst, A.E.C. · Boven, E. · Sterre, M.L.T. van der · Fichtinger-Schepman, A.M.J. · Vijgh, W.J.F. van der
Keywords: Nutrition · Amifostine · Cisplatin · Ethyol · Pharmacokinetics · WR-2721 · Amifostine · Cisplatin · Dna · Animal cell · Animal experiment · Animal model · Animal tissue · Area under the curve · Article · Bone marrow · Controlled study · Dna adduct · Drug blood level · Drug tissue level · Female · Human · Human tissue · Intraperitoneal drug administration · Intravenous drug administration · Kidney · Liver · Mouse · Nonhuman · Nude mouse · Ovary cancer · Pharmacokinetics · Priority journal · Tumor xenograft · Amifostine · Animals · Antineoplastic Agents · Cisplatin · Drug Combinations · Drug Synergism · Female · Humans · Kidney · Liver · Mice · Neoplasm Transplantation · Ovarian Neoplasms · Platinum · Radiation-Protective Agents · Transplantation, Heterologous
[Abstract]

2 Pharmacodynamics of cisplatin in human head and neck cancer : correlation between platinum content, DNA adduct levels and drug sensitivity in vitro and in vivo
article 1999    
Author: Welters, M.J.P. · Fichtinger-Schepman, A.M.J. · Baan, R.A. · Jacobs-Bergmans, A.J. · Kegel, A. · Vijgh, W.J.F. van der · Braakhuis, B.J.M.
Keywords: Cisplatin · Cisplatin sensitivity · DNA adducts · Head and neck cancer · Platinum accumulation · DNA · phosphorus 32 · platinum · animal experiment · animal tissue · atomic absorption spectrometry · cancer cell culture · controlled study · DNA drug complex · drug sensitivity · human cell · intravenous drug administration · mouse · nonhuman · nude mouse · pharmacodynamics · radioassay · squamous cell carcinoma · tumor xenograft · Animals · Antineoplastic Agents · Carcinoma, Squamous Cell · Drug Screening Assays, Antitumor · Female · Head and Neck Neoplasms · Humans · Mice · Mice, Nude · Neoplasm Transplantation · Tumor Cells, Cultured
[PDF] [Abstract]

3 Tissue inhibitor of metalloproteinase-3 expression from an oncolytic adenovirus inhibits matrix metalloproteinase activity in vivo without affecting antitumor efficacy in malignant glioma
article 2005    
Author: Lamfers, M.L.M. · Gianni, D. · Tung, C.H. · Idema, S. · Schagen, F.H.E. · Carette, J.E. · Quax, P.H.A. · Beusechem, V.W. van · Top, W.P. van der · Dirven, C.M.F. · Chiocca, E.A. · Gerritsen, W.R.
Keywords: Biomedical Research · oncolytic adenovirus · oncolytic virus · tissue inhibitor of metalloproteinase 3 · Adenovirus · animal experiment · animal model · animal tissue · antineoplastic activity · article · cancer cell culture · cancer model · cancer survival · cell proliferation · cell strain HEK293 · controlled study · culture medium · drug efficacy · enzyme activity · enzyme inhibition · female · gene deletion · gene expression · gene insertion · gene transfer · glioblastoma · glioma cell · human · human cell · mouse · nonhuman · priority journal · protein expression · survival time · transgene · tumor xenograft · Adenoviridae · Animals · Cell Growth Processes · Cell Line, Tumor · Gene Transfer Techniques · Glioma · Humans · Matrix Metalloproteinase 2 · Mice · Mice, Nude · Tissue Inhibitor of Metalloproteinase-3 · Virus Replication · Xenograft Model Antitumor Assays
[Abstract]

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