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21 Fenofibrate increases HDL-cholesterol by reducing cholesteryl ester transfer protein expression
article 2007    
Author: Hoogt, C.C. van der · Haan, W. de · Westerterp, M. · Hoekstra, M. · Dallinga-Thie, G.M. · Romijn, J.A. · Princen, H.M.G. · Jukema, J.W. · Havekes, L.M. · Rensen, P.C.N.
Keywords: Health · Biomedical Research · Fibrate · High density lipoprotein · Peroxisome proliferator-activated receptor α · Transgenic mice · apolipoprotein E · cholesterol ester transfer protein · fenofibrate · high density lipoprotein cholesterol · very low density lipoprotein · animal experiment · cholesterol transport · controlled study · drug mechanism · food intake · gene expression · lipid metabolism · mouse · nonhuman · priority journal · protein expression · protein function · steady state · transgene · Animals · Antilipemic Agents · Apolipoproteins B · Cholesterol Ester Transfer Proteins · Cholesterol Esters · Cholesterol, HDL · Gene Expression · Humans · Liver · Male · Mice · Mice, Transgenic · Procetofen · RNA, Messenger
[PDF] [Abstract]

22 Predicting individual responses to pravastatin using a physiologically based kinetic model for plasma cholesterol concentrations
article 2014    
Author: Pas, N.C.A. van de · Rullmann, J.A.C. · Woutersen, R.A. · Ommen, B. van · Rietjens, I.M.C.M. · Graaf, A.A. de
Keywords: Biology · Cholesterol · LDL · PBK modeling · Personalized medicine · Statin response · Virtual subjects · cholesterol · High density lipoprotein cholesterol · Low density lipoprotein cholesterol · Low density lipoprotein receptor · Pravastatin · Very low density lipoprotein cholesterol · Cholesterol blood level · Cholesterol synthesis · Drug effect · Drug mechanism · Human · Kinetics · Major clinical study · Monte Carlo method · Physiologically based kinetic · Protein expression · Biomedical Innovation · Healthy Living · Life · MSB - Microbiology and Systems Biology · ELSS - Earth, Life and Social Sciences
[Abstract]

23 Carotenoid interactions
article 1999    
Author: Berg, H. van den
Keywords: Nutrition · Chemistry · Analyse · Alpha carotene · Beta carotene · Canthaxanthin · Carotenoid · Chylomicron · High density lipoprotein · Low density lipoprotein · Lycopene · Triacylglycerol · Very low density lipoprotein · Xanthophyll · Zeaxanthin · Area under the curve · Dietary intake · Dose response · Ferret · Fruit · Human · Intestine absorption · Liver · Metabolism · Mitosis inhibition · Nonhuman · Nutrition · Postprandial state · Prophylaxis · Review · Small intestine mucosa · Smoking · Tissue distribution · Transport kinetics · Vegetable · Vitamin blood level · Administration, Oral · Animals · Carotenoids · Chylomicrons · Drug Interactions · Humans · Intestinal Absorption
[Abstract]

24 Apolipoprotein C-I binds free fatty acids and reduces their intracellular esterification
article 2007    
Author: Westerterp, M. · Berbée, J.F.P. · Delsing, D.J.M. · Jong, M.C. · Gijbels, M.J.J. · Dahlmans, V.E.H. · Offerman, E.H. · Romijn, J.A. · Havekes, L.M. · Rensen, P.C.N.
Keywords: Biology · Biomedical Research · Lipoprotein · Lipoprotein lipase · Skin · Triglyceride · very low density lipoprotein · animal cell · animal experiment · animal tissue · controlled study · electricity · esterification · female · in vitro study · mouse · nonhuman · phenotype · skin transplantation · wild type · Animals · Apolipoprotein C-I · Cells, Cultured · Enzyme-Linked Immunosorbent Assay · Esterification · Fatty Acids, Nonesterified · Female · Humans · Lipoproteins, VLDL · Macrophages · Male · Mice · Mice, Inbred C57BL · Mice, Knockout · Mice, Transgenic · Oleic Acid · Phenotype · Protein Binding · Skin · Skin Abnormalities · Skin Transplantation
[PDF] [Abstract]

25 Effect of apolipoprotein E and insulin resistance on VLDL particles in combined hyperlipidemic patients
article 1996    
Author: Sijbrands, E.J.G. · Westendorp, R.G.J. · Hoffer, M.J.V. · Frants, R.R. · Meinders, A.E. · Souverijn, J.H.M. · Leuven, J.A.G. · Laarse, A. van der · Havekes, L.M. · Smelt, A.H.M.
Keywords: Biology · ApoE · Combined hyperlipidemia · Hyperinsulinemia · Particle size · VLDL · apolipoprotein e · insulin · very low density lipoprotein · adult · aged · article · clinical trial · controlled clinical trial · controlled study · diet · female · genetic analysis · heterozygosity · human · human tissue · hyperlipidemia · hypertriglyceridemia · insulin resistance · lipid analysis · major clinical study · male · priority journal · Adult · Aged · Apolipoproteins E · Cholesterol, VLDL · Fasting · Female · Humans · Hyperlipidemia, Familial Combined · Insulin · Insulin Resistance · Lipoproteins, VLDL · Male · Middle Aged · Particle Size · Triglycerides
[Abstract]

26 Effects of fish oil on oxidation resistance of VLDL in hypertriglyceridemic patients
article 1996    
Author: Hau, M.-F. · Smelt, A.H.M. · Bindels, A.J.G.H. · Sijbrands, E.J.G. · Laarse, A. van der · Onkenhout, W. · Duyvenvoorde, W. van · Princen, H.M.G.
Keywords: Biology · fish oil · hypertriglyceridemia · LDL oxidation · omega-3 fatty acids · VLDL oxidation · alpha tocopherol · cholesterol · fish oil · high density lipoprotein cholesterol · low density lipoprotein cholesterol · omega 3 fatty acid · polyunsaturated fatty acid · triacylglycerol · very low density lipoprotein cholesterol · adult · article · clinical article · diet supplementation · fat intake · fatty acid blood level · human · hyperlipidemia · hypertriglyceridemia · lipid blood level · lipid oxidation · lipoprotein blood level · male · oral drug administration · priority journal · Adult · Diet · Fish Oils · Humans · Hypertriglyceridemia · Lipid Peroxidation · Lipoproteins, VLDL · Male · Middle Aged
[Abstract]

27 Sex steroids and lipoprotein metabolism
article 1994    
Author: Gevers Leuven, J.A.
Keywords: Health · Cardiovascular risk · Cholesterol · Estrogens · Lipoproteins · Progestogens · Sex steroids · chlormadinone acetate · cholesterol · conjugated estrogen · cyproterone acetate · desogestrel · dydrogesterone · gestodene · high density lipoprotein · hydroxytamoxifen · low density lipoprotein · lynestrenol · medrogestone · medroxyprogesterone acetate · mifepristone · norethisterone · noretynodrel · norgestimate · norgestrel · oral contraceptive agent · sex hormone · steroid receptor · very low density lipoprotein · atherogenesis · cardiovascular disease · drug structure · lipid metabolism · lipoprotein metabolism · Animal · Arteriosclerosis · Cardiovascular Diseases · Contraceptives, Oral, Hormonal · Female · Human · Lipoproteins · Male · Risk Factors · Sex Hormones
[Abstract]

28 Uptake by J774 macrophages of very-low-density lipoproteins isolated from apoE-deficient mice is mediated by a distinct receptor and stimulated by lipoprotein lipase
article 1997    
Author: Hendriks, W.L. · Sman van der - Beer, F. de · Vlijmen, B.J.M. van · Vark, L.C. van · Hofker, M.H. · Havekes, L.M.
Keywords: Biology · apoE-deficient mice · foam cells · lipoprotein lipase · macrophages · receptor-mediated uptake · apolipoprotein a1 · apolipoprotein a4 · apolipoprotein b100 · apolipoprotein c · cholesterol ester · lipoprotein receptor · receptor protein · triacylglycerol · very low density lipoprotein · animal cell · animal experiment · animal model · atherosclerotic plaque · cell line · controlled study · foam cell · hyperlipoproteinemia type 3 · intima · lipoprotein metabolism · macrophage · mouse · nonhuman · Animals · Apolipoproteins E · Biological Transport · Cell Line · Lipoprotein Lipase · Lipoproteins, VLDL · Macrophages · Mice · Radioligand Assay · Receptors, Lipoprotein
[Abstract]

29 Genetic heterogeneity of apolipoprotein E and its influence on plasma lipid and lipoprotein levels
article 1994    
Author: Knijff, P. de · Maagdenberg, A.M.J.M. van den · Frants, R.R. · Havekes, L.M.
Keywords: Biology · Apolipoprotein (apo) E · Atherosclerosis · Familial Dysbetalipoproteinemia (FD) · Mutations · Polymorphisms · Type III Hyperlipoproteinemia · Cholesterol · Chylomicron · Low density lipoprotein receptor · Triacylglycerol · Very low density lipoprotein · Alzheimer disease · Atherosclerosis · Cholesterol blood level · Coronary artery disease · Creutzfeldt jakob disease · Gene mutation · Genetic heterogeneity · Genetic linkage · Genetic polymorphism · Ligand binding · Lipoprotein metabolism · Alleles · Amino Acid Sequence · Base Sequence · DNA · Female · Gene Frequency · Human · Hyperlipidemia · Hyperlipoproteinemia Type III · Lipids · Lipoproteins · Male · Molecular Sequence Data · Mutation · Variation (Genetics)
[Abstract]

30 Apolipoproteins modulate the inflammatory response to lipopolysaccharide
article 2005    
Author: Berbée, J.F.P. · Havekes, L.M. · Rensen, P.C.N.
Keywords: Biology · Biomedical Research · Apolipoprotein E · Hepatocyte · Lipid metabolism · Lipopolysaccharide · Lipoprotein · Apolipoprotein · Apolipoprotein A1 · Apolipoprotein E · Cholesterol · High density lipoprotein · Lipid transfer protein · Low density lipoprotein · Triacylglycerol · Very low density lipoprotein · Cholesterol blood level · Death · Enzyme blood level · In vitro study · Inflammation · Lipid analysis · Lipoprotein metabolism · Nonhuman · Protein binding · Rodent · Triacylglycerol blood level · Animals · Apolipoproteins · Apolipoproteins E · Humans · Inflammation · Lipids · Lipopolysaccharides · Lipoproteins · Sepsis · Bacteria (microorganisms) · Rodentia
[Abstract]

31 Differential effects of amlodipine and atorvastatin treatment and their combination on atherosclerosis in ApoE*3-Leiden transgenic mice
article 2003    
Author: Delsing, D.J.M. · Jukema, J.W. · Wiel, M.A. van de · Emeis, J.J. · Laarse, A. van der · Havekes, L.M. · Princen, H.M.G.
Keywords: Biology · Biomedical Research · Atherosclerosis · Calcification · Calcium antagonists · Inflammation · Statins · Amlodipine · Atorvastatin · Hydroxymethylglutaryl coenzyme A reductase inhibitor · Very low density lipoprotein cholesterol · Animal model · Animal tissue · Aorta root · Cholesterol blood level · Cholesterol diet · Controlled study · Drug effect · Inflammation · Mouse · Nonhuman · Amlodipine · Animals · Aorta, Thoracic · Apolipoprotein E3 · Apolipoproteins E · Arteriosclerosis · Blood Pressure · Calcium Channel Blockers · Cholesterol · Cholesterol, Dietary · Drug Therapy, Combination · Female · Heptanoic Acids · Hydroxymethylglutaryl-CoA Reductase Inhibitors · Mice · Mice, Transgenic · Pyrroles
[Abstract]

32 Modulating effect of the A-278C promoter polymorphism in the cholesterol 7alpha-hydroxylase gene on serum lipid levels in normolipidaemic and hypertriglyceridaemic individuals
article 2004    
Author: Hofman, M.K. · Groenendijk, M. · Verkuijlen, P.J.J.H. · Jonkers, I.J.A.M. · Mohrschladt, M.F. · Smelt, A.H.M. · Princen, H.M.G.
Keywords: Biology · Biomedical Research · CYP7A1 · Hyperlipidaemia · Modifier gene · Polymorphism · Triglycerides · apolipoprotein E3 · cholesterol · cholesterol 7alpha monooxygenase · isoprotein · lipid · low density lipoprotein · triacylglycerol · very low density lipoprotein · controlled study · DNA polymorphism · familial hypercholesterolemia · gene control · homozygosity · hyperlipidemia · hyperlipoproteinemia type 3 · lipid blood level · major clinical study · promoter region · triacylglycerol blood level · Adult · Aged · Cholesterol 7-alpha-Hydroxylase · Female · Gene Frequency · Genotype · Humans · Hypertriglyceridemia · Male · Middle Aged · Polymorphism, Genetic · Promoter Regions (Genetics) · Triglycerides
[Abstract]

33 Hepatic glucose production is more sensitive to insulin-mediated inhibition than hepatic VLDL-triglyceride production
article 2006    
Author: Boer, M.A.M. den · Voshol, P.J. · Kuipers, F. · Romijn, J.A. · Havekes, L.M.
Keywords: Biology · Biomedical Research · Euglycemic hyperinsulinemic clamp · Fatty acid · Very-low-density lipoprotein · Insulin · Adipose tissue · Animal experiment · Aanimal model · Controlled study · Drug effect · Drug inhibition · Fatty acid blood level · Gluconeogenesis · Glucose infusion · Glucose transport · Hyperinsulinemia · Insulin blood level · Insulin resistance · Insulin sensitivity · Lipolysis · Liver function · Mouse · Nonhuman · Animals · Blood Glucose · Dose-Response Relationship, Drug · Fatty Acids, Nonesterified · Glucose · Glucose Clamp Technique · Hypoglycemic Agents · Insulin · Kinetics · Lipoproteins, VLDL · Liver · Male · Mice · Mice, Inbred C57BL · Triglycerides
[Abstract]

34 Apolipoprotein CI deficiency markedly augments plasma lipoprotein changes mediated by human cholesteryl ester transfer protein (CETP) in CETP transgenic/apoCI-knocked out mice
article 2002    
Author: Gautier, T. · Masson, D. · Jong, M.C. · Duverneuil, L. · Guern, N.L. · Deckert, V. · Barros, J.-P.P.de · Dumont, L. · Bataille, A. · Zak, Z. · Jiang, X.-C. · Tall, A.R. · Havekes, L.M. · Lagrost, L.
Keywords: Biology · Cholesterol · Chromatographic analysis · Esters · Proteins · Apolipoproteins · Biochemistry · High density lipoprotein · Very low density lipoprotein · Animal experiment · Concentration response · Controlled study · Gel permeation chromatography · Knockout mouse · Lipoprotein blood level · Mouse · Nonhuman · Protein deficiency · Protein expression · Transgenic mouse · Animals · Apolipoprotein C-I · Apolipoproteins C · Carrier Proteins · Cholesterol Ester Transfer Proteins · Glycoproteins · Humans · Kinetics · Lipoproteins · Mice · Mice, Inbred C57BL · Mice, Knockout · Mice, Transgenic · Animalia · Mus musculus
[PDF] [Abstract]

35 Inhibition of the central melanocortin system decreases brown adipose tissue activity
article 2014    
Author: Kooijman, S. · Boon, M.R. · Parlevliet, E.T. · Geerling, J.J. · Pol, V. van de · Romijn, J.A. · Havekes, L.M. · Meurs, I. · Rensen, P.C.N.
Keywords: Biology · Energy expenditure · Liver · Triglycerides · Very low density lipoprotein · White adipose tissue · Apolipoprotein E · Fat droplet · Melanocortin · Melanocortin 3 receptor · Melanocortin 4 receptor · N acetyl alpha intermedin[4-10]cyclo[4 norleucine 5 aspartic acid 7 [3 (2 naphthyl)alanine] 10 lysinamide] · Triacylglycerol · Uncoupling protein 1 · Animal experiment · Animal tissue · Body fat · Brown adipose tissue · Central melanocortin system · Controlled study · Dyslipidemia · Endocrine system · Fat mass · Fatty liver · Female · Food intake · Hormone inhibition · Lipid analysis · Lipid oxidation · Lipid storage · Mouse · Nonhuman · Obesity · Signal transduction · Weight gain · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · ELSS - Earth, Life and Social Sciences
[PDF] [Abstract]

36 A low-fat diet has a higher potential than energy restriction to improve high-fat diet-induced insulin resistance in mice
article 2002    
Author: Muurling, M. · Jong, M.C. · Mensink, R.P. · Hornstra, G. · Dahlmans, V.E.H. · Pijl, H. · Voshol, P.J. · Havekes, L.M.
Keywords: Biology Health · fat · fatty acid · glucose · high density lipoprotein · insulin · intermediate density lipoprotein · low density lipoprotein · triacylglycerol · very low density lipoprotein · animal experiment · animal model · article · body weight · caloric intake · controlled study · energy metabolism · feeding · glucose tolerance · insulin blood level · insulin dependent diabetes mellitus · insulin resistance · insulin sensitivity · lipid diet · lipid metabolism · low fat diet · male · mouse · non insulin dependent diabetes mellitus · nonhuman · obesity · priority journal · Animals · Blood Glucose · Body Weight · Cholesterol · Dietary Fats · Energy Intake · Fatty Acids, Nonesterified · Glucose Tolerance Test · Insulin · Insulin Resistance · Lipids · Lipoproteins · Lipoproteins, VLDL · Liver · Male · Mice · Mice, Inbred C57BL · Polyethylene Glycols · Triglycerides
[Abstract]

37 The dual PPARα/γ agonist tesaglitazar blocks progression of pre-existing atherosclerosis in APOE*3Leiden.CETP transgenic mice
article 2009    
Author: Hoorn, J.W.A. van der · Jukema, J.W. · Havekes, L.M. · Lundholm, E. · Camejo, G. · Rensen, P.C.N. · Princen, H.M.G.
Keywords: Biology · Biomedical Research · 3Leiden.CETP mice · APOE · Atherogenic triad · Atherosclerosis · PPARα/γ · Tesaglitazar · 2 ethoxy 3 (4 ((4 (methylsulfonyloxy)phenethyl)oxy)phenyl)propanoic acid · Alkanesulfonic acid · High density lipoprotein cholesterol · Peroxisome proliferator activated receptor alpha · Peroxisome proliferator activated receptor gamma · Phenylpropionic acid derivative · Very low density lipoprotein cholesterol · Biosynthesis · Blood · Drug potentiation · Genetics · Inflammation · Metabolism · Mouse · Mutation · Pathology · Transgenic mouse · Alkanesulfonates · Animals · Aortic Valve · Apolipoprotein E3 · Atherosclerosis · Cholesterol Ester Transfer Proteins · Cholesterol, HDL · Cholesterol, VLDL · Female · Humans · Inflammation · Mice · Mice, Transgenic · Mutation · Phenylpropionates · PPAR alpha · PPAR gamma
[Abstract]

38 Anacetrapib reduces (V)LDL-cholesterol by inhibition of CETP activity and reduction of plasma PCSK9
article 2015    
Author: Tuin, S.J. van der · Kühnast, S. · Berbée, J. · Verschuren, L. · Pieterman, E.J. · Havekes, L.M. · Hoorn, J.W. van der · Rensen, P.C. · Jukema, J.W. · Princen, H.M. · Willems van Dijk, K. · Wang, Y.
Keywords: Health · CETP · Cholesterol · Metabolism · Drug therapy · Hypolipidemic drugs · LDL · Metabolism · Lipids · Lipoproteins · PCSK9 · Anacetrapib · Apolipoprotein B · Cholesterol ester transfer protein · Low density lipoprotein receptor · Proprotein convertase subtilisin kexin type 9 · RNA · Serine proteinase · Sterol regulatory element binding protein 1 · Sterol regulatory element binding protein 2 · Triacylglycerol · Unclassified drug · Very low density lipoprotein cholesterol · Animal experiment · Animal tissue · Atherosclerosis · Cholesterol synthesis · Controlled study · Down regulation · Drug mechanism · Enzyme blood level · Female · Liver · Microarray analysis · Mouse · Nonhuman · Polymerase chain reaction · Protein expression · RNA isolation · Western diet · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research MSB - Microbiology and Systems Biology · ELSS - Earth, Life and Social Sciences
[PDF] [Abstract]

39 Effects of simvastatin on plasma lipids and apolipoproteins in familial hypercholesterolemic swine
article 1996    
Author: Hasler-Rapacz, J. · Kempen, H.J. · Princen, H.M.G. · Kudchodkar, B.J. · Lacko, A. · Rapacz, J.
Keywords: Biology · animal model · apolipoproteins · familial hypercholesterolemia · simvastatin · swine · apolipoprotein a · apolipoprotein b · apolipoprotein c3 · apolipoprotein e · high density lipoprotein cholesterol · hydroxymethylglutaryl coenzyme a reductase · lathosterol · lipid · low density lipoprotein cholesterol · phosphatidylcholine sterol acyltransferase · simvastatin · triacylglycerol · very low density lipoprotein cholesterol · animal experiment · animal model · animal tissue · article · calculation · cholesterol blood level · dose response · enzyme activity · hypercholesterolemia · hyperlipidemia · lipid analysis · lipid blood level · lipoprotein blood level · nonhuman · priority journal · statistical analysis · swine · Animals · Apolipoprotein A-I · Apolipoprotein C-III · Apolipoproteins · Apolipoproteins B · Apolipoproteins C · Apolipoproteins E · Cholesterol · Cholesterol, HDL · Cholesterol, LDL · Enzyme Inhibitors · Female · Hydroxymethylglutaryl-CoA Reductase Inhibitors · Hyperlipoproteinemia Type II · Lipids · Male · Swine · Swine Diseases · Triglycerides
[Abstract]

40 Hyperlipidaemia is associated with increased insulin-mediated glucose metabolism, reduced fatty acid metabolism and normal blood pressure in transgenic mice overexpressing human apolipoprotein C1
article 2001    
Author: Koopmans, S.J. · Jong, M.C. · Que, I. · Dahlmans, V.E.H. · Pijl, H. · Radder, J.K. · Frölich, M. · Havekes, L.M.
Keywords: Biology · APOC1 · Hypertension · Insulin resistance · Insulin resistance syndrome · Lipoprotein · NEFA · Fatty acid · Palmitic acid · Triacylglycerol · Tritium · Very low density lipoprotein · Adipose tissue · Animal model · Animal tissue · Blood pressure · Cholesterol blood level · Clearance · Controlled study · Fatty acid metabolism · Gene overexpression · Glucose blood level · Glucose clamp technique · Glucose metabolism · Glycogen synthesis · Glycolysis · Heart rate · Hyperinsulinemia · Hyperlipidemia · Hypertension · In vivo study · Infusion · Insulin resistance · Lipid transport · Lipogenesis · Mean arterial pressure · Mouse · Nonhuman · Skeletal muscle · Transgenic mouse · Animals · Apolipoprotein C-I · Apolipoproteins C · Blood Glucose · Blood Pressure · Cholesterol · Fatty Acids, Nonesterified · Gene Expression · Glucose · Glucose Clamp Technique · Glycogen · Humans · Hyperlipidemias · Insulin · Lipid Metabolism · Liver · Mice · Mice, Transgenic · Muscle, Skeletal · Palmitic Acid · Triglycerides · Tritium
[Abstract]

Search results also available in MS Excel format.

Prev Showing 21 to 40 of 54 found. Next | Sort by date