Repository hosted by TU Delft Library

Home · Contact · About · Disclaimer ·
 

Search results also available in MS Excel format.

Showing 1 to 5 of 5 found. | Sort by date

1 Protective activity of adenosine receptor agonists in the treatment of organophosphate poisoning
article 1999    
Author: Helden, H.P.M. van · Bueters, T.J.H.
Keywords: Toxicology · 1 (4 carbamoylpyridinio) 1' (2 hydroxyiminomethylpyridinio)dimethyl ether · 6 n cyclopentyladenosine · Animals · Humans · Organophosphorus Compounds · Poisoning · Receptors, Purinergic P1

2 Increasing oxime efficacy by blood-brain barrier modulation
article 2011    
Author: Joosen, M.J.A. · Schans, M.J. van der · Dijk, C.G.M. van · Kuijpers, W.C. · Wortelboer, H.M. · Helden, H.P.M. van
Keywords: HI6 · Nerve agent · P-glycoprotein · Seizures · Tariquidar · 1 (4 carbamoylpyridinio) 1' (2 hydroxyiminomethylpyridinio)dimethyl ether · Acetylcholinesterase · Atropine · Tariquidar · Animal experiment · Animal model · Article · Blood brain barrier · Blood level · Brain blood volume · Controlled study · Convulsion · Drug effect · Drug efficacy · Drug intoxication · Drug penetration · Male · Microdialysis · Modulation · Nerve agent poisoning · Nonhuman · Priority journal · Quantitative analysis · Rat · Seizure · Rattus · 1 (4 carbamoylpyridinio) 1' (2 hydroxyiminomethylpyridinio)dimethyl ether, 34433-31-3 · Acetylcholinesterase, 9000-81-1 · Atropine, 51-55-8, 55-48-1 · Tariquidar, 206873-63-4 · Tradenames: hi 6, TNO; xr 9576, avaant · Manufacturers: TNO; avaant · Life · CBRN - CBRN Protection PHS - Pharmacokinetics & Human Studies · EELS - Earth, Environmental and Life Sciences
[Abstract]

3 Therapy of organophosphate poisoning in the rat by direct effects of oximes unrelated to ChE reactivation
article 1991    
Author: Helden, H.P.M. van · Lange, J. de · Busker, R.W. · Melchers, B.P.C.
Keywords: Biology · Acetylcholinesterase · Direct effect · HGG-12 · HI-6 · Obidoxime · Organophosphate poisoning · P2S · 1 (4 carbamoylpyridinio) 1' (2 hydroxyiminomethylpyridinio)dimethyl ether · [(3 benzoyl 1 pyridiniomethyl) (2 hydroxyiminomethyl 1 pyridiniomethyl)] ether · Obidoxime · Organophosphate · Oxime · Soman · Animal experiment · Animal tissue · Diaphragm · Enzyme inhibition · Enzyme reactivation · Intravenous drug administration · Male · Nonhuman · Priority journal · Rat · Animal · Antidotes · Blood-Brain Barrier · Cholinesterase Reactivators · Diaphragm · In Vitro · Male · Neuromuscular Junction · Obidoxime Chloride · Organophosphorus Compounds · Oximes · Pralidoxime Compounds · Pyridinium Compounds · Rats · Respiratory Insufficiency · Synaptic Transmission · Animalia
[Abstract]

4 Successful oxime therapy one hour after soman intoxication in the rat
article 1978    
Author: Wolthuis, O.L. · Kepner, L.A.
Keywords: Biology · 1 (3 carbamoylpyridinio) 1' (2 hydroxyiminomethylpyridinio)dimethyl ether · 1 (4 carbamoylpyridinio) 1' (2 hydroxyiminomethylpyridinio)dimethyl ether · Atropine · Cholinesterase · Oxime · Radioisotope · Soman · Acetylcholine h 3 · Aging · Animal experiment · Breathing · Cytology · Diaphragm · Drug comparison · Drug intoxication · In vitro study · Intoxication · Muscle · Neuromuscular transmission · Peripheral nervous system · Phrenic nerve · Rat · Respiratory failure · Respiratory system · Animal · Atropine · Cholinesterases · Diaphragm · Male · Muscle Contraction · Organophosphorus Compounds · Oximes · Phrenic Nerve · Rats · Soman · Time Factors
[Abstract]

5 The efficacy of some bis-pyridinium oximes as antidotes to soman in isolated muscles of several species including man
article 1981    
Author: Wolthuis, O. · Vanwersch, R.A.P. · Wiel, H.J. van der
Keywords: Biology · 1 (3 carbamoylpyridinio) 1' (2 hydroxyiminomethylpyridinio)dimethyl ether · 1 (4 carbamoylpyridinio) 1' (2 hydroxyiminomethylpyridinio)dimethyl ether · [(3 isobutyryl 1 pyridiniomethyl) (2 hydroxyiminomethyl 1 pyridiniomethyl)] ether · Sarin · Soman · Tubocurarine chloride · Unclassified drug · Animal experiment · Bispyridinium oxime · Diaphragm · Dog · Dose response · Drug comparison · Drug response · Guinea pig · Human cell · In vitro study · Intercostal muscle · Intravenous drug administration · Neuromuscular transmission · Rat · Adult · Aged · Animal · Antidotes · Chorionic Gonadotropin · Comparative Study · Dogs · Electric Stimulation · Female · Guinea Pigs · Human · In Vitro · Male · Middle Age · Neuromuscular Junction · Organophosphorus Compounds · Pralidoxime Compounds · Pyridinium Compounds · Rats · Sarin · Soman · Species Specificity · Synaptic Transmission
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 5 of 5 found. | Sort by date